Removal of ceftriaxone and ciprofloxacin antibiotics from aqueous solutions using graphene oxide derived from corn cob by . Rinawati, A. Rahmawati, D.R. Muthia, M.D. Imelda, F.H. Latief, S. Mohamad, A.A. Kiswandono

“…BACKGROUND AND OBJECTIVES: Preliminary studies on the exploration of carbonaceous materials from agricultural waste and their use as adsorbents for antibiotic removal have shown the potential to address a new threat to human health due to antibiotic residue. Therefore, this study developed and synthesized graphene oxide from corn cob for its efficiency in removing ceftriaxone and ciprofloxacin.METHODS: The Hummers methods were used to synthesize graphene oxide from corn cobs. …”
Get full text

TRIM25: A Global Player of Cell Death Pathways and Promising Target of Tumor-Sensitizing Therapies by Wolfgang Eberhardt, Usman Nasrullah, Josef Pfeilschifter

“…Therapy resistance still constitutes a common hurdle in the treatment of many human cancers and is a major reason for treatment failure and patient relapse, concomitantly with a dismal prognosis. …”
Get full text

Deep-Sea Ecosystems as an Unexpected Source of Antibiotic Resistance Genes by Wei Zhang, Yingdong Li, Yunmeng Chu, Hao Liu, Hongmei Jing, Qianfeng Xia

“…The ratio of nonsynonymous to synonymous substitutions (pN/pS) values of these genes suggest different evolutionary strategies in response to deep-sea conditions and possible human impacts. These resistome profiles provide valuable insights into their natural origins as well as the ecological and evolutionary implications of antibiotic resistance in deep-sea ecosystems. …”
Get full text

The Application of CA and PCA to the Evaluation of Lipophilicity and Physicochemical Properties of Tetracyclic Diazaphenothiazine Derivatives by Anna Nycz–Empel, Katarzyna Bober, Mirosław Wyszomirski, Ewa Kisiel, Andrzej Zięba

“…Using computer programs, based on different computational algorithms, theoretical values of lipophilicity (AClogP, ALOGP, ALOGPs, miLogP, MLOGP, XLOGP2, and XLOGP3) as well as molecular descriptors (molecular weight, volume of a molecule, dipole moment, polar surface, and energy of HOMO orbitals and LUMO orbitals) and parameters of biological activity: human intestinal absorption (HIA), plasma protein binding (PPB), and blood-brain barrier (BBB), were determined. …”
Get full text

Dual specific STAT3/5 degraders effectively block acute myeloid leukemia and natural killer/T cell lymphoma by Daniel Pölöske, Helena Sorger, Anna Schönbichler, Elvin D. deAraujo, Heidi A. Neubauer, Anna Orlova, Sanna H. Timonen, Diaaeldin I. Abdallah, Aleksandr Ianevski, Heikki Kuusanmäki, Marta Surbek, Elisabeth Heyes, Thomas Eder, Christina Wagner, Tobias Suske, Martin L. Metzelder, Michael Bergmann, Maik Dahlhoff, Florian Grebien, Roman Fleck, Christine Pirker, Walter Berger, Emir Hadzijusufovic, Wolfgang R. Sperr, Lukas Kenner, Peter Valent, Tero Aittokallio, Marco Herling, Satu Mustjoki, Patrick T. Gunning, Richard Moriggl

“…Both JPX‐0700/−0750 treatment reduced leukemic cell growth in human AML or NKCL xenograft mouse models significantly, being well tolerated by mice. …”
Get full text

Gastroprotective properties of flavonoid-rich extract of Pulicaria odora against ethanol-induced gastric ulcer in mice by Khadidja Boudebbaz, Manel Brouk, Roumaissa Laalem, Nada Zabaiou

“…In vitro anti-inflammatory activity was investigated through the human red blood cell membrane stabilization method and the bovine serum albumin denaturation method. …”
Get full text

Starch metabolism in potato <i>Solanum tuberosum</i> L. by E. M. Sergeeva, K. T. Larichev, E. A. Salina, A. V. Kochetov

“…It is an important source of calories in the human and animal diet. Also, it is widely used in various industries. …”
Get full text

Body mass index levels in students living in areas of military conflict by Iryna Kryventsova, Katarzyna Prusik, Victoriya Klymenchenko, Olha Sokoliuk

“…Background and Study Aim. At present, human health and related elements face ongoing risks from environmental conditions. …”
Get full text

Identificación de guanacos y llamas en el registro arqueológico de los Andes centro-sur con técnicas de morfometría geométrica by Anahí Hernández, Pablo Mercolli

“…The findings offer a more detailed view of the role these species played in the diets of human populations in Quebrada during the Late Holocene.…”
Get full text

Enhanced CO2 Capture Performance Using Methyl Diethanolamine-functionalized Silica Gels: Assessing CO2 Capture Capacity by Petpitcha Boonmatoon, Pacharapol Nokpho, Pornpote Piumsomboon, Benjapon Chalermsinsuwan

“…This causes harm to the environment and to humans. In 2023, atmospheric CO2 levels rose to 420 ppm, marking a new record high. …”
Get full text

Anti-proliferative and photodynamic activities of Senna didymobotrya (Fresen.) leaf alkaloid-rich extracts against breast cancer cells by Kolawole A. Olofinsan, Heidi Abrahamse, Blassan P. George

“…Conclusion Although the in silico analysis suggests that the plant-identified alkaloid phytoconstituents inhibition of estrogen receptor-alpha, human epidermal growth factor receptor-2 and progesterone receptor proteins involved in breast cancer pathogenesis could explain a possible mechanism for the observed anticancer effect, more detailed in vitro molecular experiments are necessary to confirm these findings.…”
Get full text

Real-time rapid accident detection for optimizing road safety in Bangladesh by Md Shamsul Arefin, Md Ibrahim Shikder Mahin, Farzana Akter Mily

“…Road traffic accidents in Dhaka are among the worst in the world, along with huge human fatalities and vast economic losses. An advanced car accident detecting system using a YOLOv11 model is proposed for highly efficient real-time detection to further upgrade the emergency response systems. …”
Get full text

Parasite-Specific IL-17-Type Cytokine Responses and Soluble IL-17 Receptor Levels in Alveolar Echinococcosis Patients by Christian J. Lechner, Beate Grüner, Xiangsheng Huang, Wolfgang H. Hoffmann, Peter Kern, Peter T. Soboslay

“…These observations suggest immune-modulating properties of E. multitocularis on lL-17 cytokine-mediated pro-inflammatory immune responses; this may facilitate the tissue infiltrative growth of the parasite and its persistence in the human host.…”
Get full text

Efficacy and safety of Xiongzhitongluo granules in the treatment of acute ischemic stroke: study protocol for a randomized controlled trial by Yunmeng Chen, Jingjing Wei, Xiao Liang, Yue Liu, Lina Miao, Di Zhao, Yunfan Zhang, Hongxi Liu, Yunling Zhang

“…IntroductionAcute ischemic stroke (AIS) poses a significant risk to human health. Intravenous thrombolysis and mechanical thrombectomy are essential treatments for AIS, offering substantial benefits for neurological recovery and brain protection. …”
Get full text

Signaling, Constraining and Coercing in US sanctions policy towards Russia in the context of the Ukraine crisis by O. I. Rebro

“…Institutionally established within the scope of the executive branch, buttressed by the US dominance in the world economy and viewed as a “humane” way of influencing foreign elites, it does not demand significant political capital and, as a result, can be implemented without deep strategic thinking. …”
Get full text

DeepSeek vs. ChatGPT: Comparative Efficacy in Reasoning for Adults’ Second Language Acquisition Analysis by Mohammad Mahyoob Albuhairy, Jeehaan Algaraady

“…The advent of new generation language models has revolutionized the field of natural language processing (NLP) due to their exceptional understanding and human language generation capabilities. ChatGPT emerged as an essential model with remarkable strengths for various applications. …”
Get full text

Beyond Text Generation: Assessing Large Language Models’ Ability to Reason Logically and Follow Strict Rules by Zhiyong Han, Fortunato Battaglia, Kush Mansuria, Yoav Heyman, Stanley R. Terlecky

“…The growing interest in advanced large language models (LLMs) like ChatGPT has sparked debate about how best to use them in various human activities. However, a neglected issue in the debate concerning the applications of LLMs is whether they can reason logically and follow rules in novel contexts, which are critical for our understanding and applications of LLMs. …”
Get full text

Analysis on Flavor Quality of Brassica rapa L. from Different Varieties by MAERHABA·Paerhati, Zhanteng SONG, Ruina YANG, Jing LI, Jing AN, Min LIU, Zhenzhen XU, Jingrong ZHU

“…Results showed that the amino acids in 4 different varieties of Brassica rapa L. were all of various kinds, all containing 17 amino acids measured, including 7 essential amino acids for human body. The umami amino acids of SFB accounted for a relatively high proportion, and the sweet amino acids of KPZ accounted for a relatively high proportion. …”
Get full text

Gastric Intestinal Metaplasia: Demographic and Epidemiological Characterization in Puerto Rican Hispanics (2012-2014) by Jorge J. Cruz-Cruz, María González-Pons, Adrián Cora-Morges, Marievelisse Soto-Salgado, Giancarlo Colón, Kimberly Alicea, Kathia Rosado, Douglas R. Morgan, Marcia Cruz-Correa

“…Helicobacter pylori is the most common chronic bacterial infection in humans and the major predisposing factor for the development of gastric intestinal metaplasia (GIM), the principal preneoplastic lesion in the gastric carcinogenesis pathway. …”
Get full text

Inducing aggresome and stable tau aggregation in Neuro2a cells with an optogenetic tool by Shigeo Sakuragi, Tomoya Uchida, Naoki Kato, Boxiao Zhao, Toshiki Takahashi, Akito Hattori, Yoshihiro Sakata, Yoshiyuki Soeda, Akihiko Takashima, Hideaki Yoshimura, Gen Matsumoto, Hiroko Bannai

“…This study describes a novel optogenetic module, OptoTau, which is a human tau with the P301L mutation fused with a photosensitive protein CRY2olig, inducing various forms of tau according to the temporal pattern of blue light illumination pattern. …”
Get full text