Amphotericin B Encapsulation in Polymeric Nanoparticles: Toxicity Insights via Cells and Zebrafish Embryo Testing by Magno Maciel-Magalhães, Renata Jurema Medeiros, Nayara Cecília do Couto Guedes, Thais Morais de Brito, Gabriele Fátima de Souza, Beatriz Rodrigues Canabarro, Fausto Klabund Ferraris, Fábio Coelho Amendoeira, Helvécio Vinicius Antunes Rocha, Beatriz Ferreira de Carvalho Patricio, Isabella Fernandes Delgado

“…Zebrafish (<i>Danio rerio</i>) embryos were used as a valuable model for toxicity testing, especially because of their genetic similarity to humans and standardized developmental assessments. …”
Get full text

Stereotypes and social representations associated with pediatric surgeons among medical students, residents and physicians: a cross-sectional study by Coline Ducrot, Max Piffoux, Mathilde Payen, Sebastien Raux, Franck Rolland, Evan Gouy, Linh Nam Truong, Ariel Frajerman, Florent Vinchon, Nawale Hadouiri

“…The specialty is considered as wide, intense, meticulous, and demanding surgical specialty but also as hyperspecialized and confined to academic centers with a unique parent–child–surgeon relationship, embodying traits such as “empathy”, “humanity”, “passion”, “beautiful[ness]” and “honorab[ility]”. …”
Get full text

FTO effects the proliferation, invasion, and glycolytic metabolism of colon cancer by regulating PKM2 by Kongyan Zhang, Fei Zhang, Jiahe Wang

“…In vitro experiments utilized five human colon cancer cell lines and a normal colon epithelial cell line, with Western blotting and RT-PCR for protein and mRNA quantification, respectively, and lentiviral transfection to modulate FTO expression. …”
Get full text

Automated Bitcoin Trading dApp Using Price Prediction from a Deep Learning Model by Zhi Zhan Lua, Chee Kiat Seow, Raymond Ching Bon Chan, Yiyu Cai, Qi Cao

“…The deployed cryptocurrency trading system performs these actions automatically without human intervention, which greatly reduces barriers to entry for ordinary users and investors. …”
Get full text

The Manufacture of GMP-Grade Bone Marrow Stromal Cells with Validated In Vivo Bone-Forming Potential in an Orthopedic Clinical Center in Brazil by Rhayra B. Dias, João A. M. Guimarães, Marco B. Cury, Leonardo R. Rocha, Elaine S. da Costa, Liebert P. Nogueira, Camila Hochman-Mendez, Anneliese Fortuna-Costa, Anna Karoline F. Silva, Karin S. Cunha, Sergio A. L. de Souza, Maria Eugênia L. Duarte, Rafaela C. Sartore, Danielle C. Bonfim

“…Here, we described standard procedures adopted in our facility for the manufacture of clinical-grade BMSC products with a preserved capacity to generate bone in vivo in compliance with the Brazilian regulatory guidelines for cells intended for use in humans. Bone marrow samples were obtained from trabecular bone. …”
Get full text

Long-term storage of C-141 reference strain of melioidosis agent (<i>Burkholderia pseudomallei</i>) by E. A. Artemeva, L. A. Melnikova, A. P. Rodionov

“…Melioidosis is a highly dangerous infectious disease caused by Hazard Group II bacteria Burkholderia pseudomallei, against which specific prevention and treatment tools have not been developed yet. Both humans and animals suffer from the disease. Previously the disease was prevalent in Southeast Asia regions, but currently is reported almost in all continents of the globe. …”
Get full text

Impacts of meteorology and emission reductions on haze pollution during the lockdown in the North China Plain by L. Liu, L. Liu, X. Long, Y. Li, Y. Li, Z. Zang, Z. Zang, F. Wang, Y. Han, Z. Bao, Y. Chen, T. Feng, J. Yang

“…<p>Haze events in the North China Plain (NCP) during the COVID-19 lockdown underscore the intricate challenges of air quality management amid reduced human activities. Utilizing the WRF-Chem model, we explored how sharp emission reductions and varying meteorological conditions influenced fine-particulate-matter (PM<span class="inline-formula">_2.5</span>) concentrations across the NCP. …”
Get full text

Ticks and Tick-Borne Pathogens in Wild Animals and Birds from Two Rehabilitation Facilities in Greece by Dimitrios Vourvidis, Georgia Tzouganatou, Sokratis Perdikaris, Evangelia Kofidou, Beatriz Martinez-Gonzalez, Mary Emmanouil, Emmanouil Papadogiannakis, Anastasia Komnenou, Emmanouil Angelakis

“…Ticks are temporary ectoparasites that serve as vectors for a wide range of pathogens affecting both wildlife and humans. In Greece, research on the prevalence of tick-borne pathogens in wildlife is limited. …”
Get full text

Antitumor activity of edible fishes (Channa striata and Anabas testudineus) and gastropods (Helix aspersa and Pila virens) rudimentary mucus against HT-29 cell line and its biochem... by Elumalai Devan, Hemavathi Maduraiveeran, Kavitha Raja, Arulvasu Chinnasamy, Govindan Sivalingam, Sathya Balaji, Vinoth Neelakandan, Sharon Agnita, Murugan Rajaram

“…Using the MTT assay, the mucus crude extract was evaluated for its anticancer properties against the human colon cancer cell line (HT 29). The inhibitory concentration (IC50) was determined at 100 µg/ml after 24 h. …”
Get full text

Socialization of younger students: updated priorities and content characteristics by Zarina I. Cherginskaya

“…Updated priorities have been identified (moral dignity, subjectivity, facilitation, social partnership, online and offline information-centralization) and the relevant content characteristics of the socialization of younger students: a) value and normative orientation in the system of public relations (active and conscious introduction of students to the norms and attitudes of society, as well as to traditional Russian spiritual and moral values); b) activating the subject position of students in the context of expanding the field of their self-realization, self-affirmation and social success (teaching new models of constructive interaction with other people, forming tolerance and the ability to live in a multinational and multicultural environment); c) socio-psychological protection of students in terms of priority of humane pedagogical influence, competent and safe in relation to all participants in educational relations; d) social integration of the possibilities of the education system and the family in the social formation of students (fruitful organization of cooperation between all participants in educational relations as allies and like-minded people in order to achieve a high level of socialization of younger students); e) information awareness and realistic assessment by online students of risks and ways of their timely minimization in the modern world (expanding the range of knowledge about the risk situations that students face in the digital world, forming skills to competently counter destructive online influences).…”
Get full text

Isolation and Characterization of Colistin-Resistant <i>Enterobacteriaceae</i> from Foods in Two Italian Regions in the South of Italy by Rosa Fraccalvieri, Angelica Bianco, Laura Maria Difato, Loredana Capozzi, Laura Del Sambro, Stefano Castellana, Adelia Donatiello, Luigina Serrecchia, Lorenzo Pace, Donatella Farina, Domenico Galante, Marta Caruso, Maria Tempesta, Antonio Parisi

“…The emergence of colistin-resistant <i>Enterobacteriaceae</i> in food products is a growing concern due to the potential transfer of resistance to human pathogens. This study aimed to assess the prevalence of colistin-resistant <i>Enterobacteriaceae</i> in raw and ready-to-eat food samples collected from two regions of Italy (Apulia and Basilicata) and to evaluate their resistance phenotypes and genetic characteristics. …”
Get full text

Bacterial diversity impacts as a result of combined sewer overflow in a polluted waterway by O. Calderon, H. Porter-Morgan, J. Jacob, W. Elkins

“…Species found in Newtown Creek include pelagic, marine, human and animal pathogens, hydrocarbonoclastic, and other environmental microbes.…”
Get full text

Exploring indigenous wisdom: Ethnobotanical documentation and conservation of medicinal plants in Goba District, Southwest Ethiopia by Ginjo Gitima, Ashenafi Gebre, Yericho Berhanu, Tamirat Wato

“…This study emphasizes the crucial role of traditional medicinal plants in the healthcare practices of communities and the urgent need for sustainable conservation measures to conserve these invaluable resources and indigenous knowledge for the long-term benefit of both human health and biodiversity conservation.…”
Get full text

Global, regional, and national lifetime risk of developing and dying from lung cancer in 2022: A population-based study in 185 countries by Meng Li, Xin Wen, Xin Liang, Mengwen Liu, Li Zhang, Rongshou Zheng, Jing Ni

“…The lung cancer risks in countries or regions worldwide were compared by region and the Human Development Index (HDI). Results:. The global lifetime risk of developing and dying from lung cancer in 2022 was 3.49% and 2.69%, respectively. …”
Get full text

A Virtual Reality Platform for Safety Training in Coal Mines with AI and Cloud Computing by Mei Li, Zhenming Sun, Zhan Jiang, Zheng Tan, Jinchuan Chen

“…However, it still has some drawbacks, such as expensive and unsuitable hardware, lack of satisfactory user experience, without direct browser access, and lack of humanized and intelligent design. To solve these problems, a cloud-based VR system is designed for the training of coal miners in this paper. …”
Get full text

Towards targeted cancer therapy: Synthesis, characterization, and biological activity of a new Cu(II)-ibuprofen-2,2′-dipyridylamine metal complex by Luís P.G. Monteiro, A. Gomes, C. Silva, Ricardo F. Mendes, Filipe A. Almeida Paz, Dmitry Chernyshov, J. Rocha, F. Martel, T.M. Santos, B.J.M. Leite Ferreira

“…Finally, the copper compound exhibited promising in vitro antitumoral activities against human breast cancer cell lines (MCF-7 and MDA-MB-231), as evaluated by MTT (3-[4,5-dimethylthiazol-2-yl]-2,5 diphenyl tetrazolium bromide) assay (although a similar cytotoxic effect against a non-tumoral epithelial cancer cell line, MCF-12A, was found), and increased oxidative stress levels as assessed by the TBARS (thiobarbituric acid reactive substances) assay and by evaluating glutathione levels. …”
Get full text

Repetitive Control of Robotic Joint With Variable Impedance Utilizing Agonist-Antagonist Muscle Pair Structure Based on Virtual Trajectories by Kaho Umeda, Yinlai Jiang, Hiroshi Yokoi, Shunta Togo

“…In this study, the repetitive control based on virtual trajectory, which is a model-free control method proposed for flexible human multi-joints, is extended and applied to a real robotic joint with a variable mechanical impedance mechanism. …”
Get full text

A Dynamic Discretization Algorithm for Learning BN Model: Predicting Causation Probability of Ship Collision in the Sunda Strait, Indonesia by Iis Dewi Ratih, Ketut Buda Artana, Heri Kuswanto, Dhimas Widhi Handani, Renata Zahabiya

“…The contributing factors to ship collisions include weather conditions, technical failure, insufficient resources, navigation errors, human error, and the failure of other vessels. The Bayesian Network (BN) machine learning method is capable of predicting ship collisions. …”
Get full text

Advancing biomonitoring of eDNA studies with the Anaconda R package: Integrating soil and One Health perspectives in the face of evolving traditional agriculture practices. by Pierre-Louis Stenger, Audrey Léopold, Kelly Dinh, Pierre Mournet, Nadia Robert, Julien Drouin, Jacques Wamejonengo, Sylvie Russet, Thomas Ibanez, Laurent Maggia, Fabian Carriconde

“…Over-represented microbial ASVs associated with both plant and animal pathogens, including those of potential concern for human health, were identified. This underscores the importance of maintaining intrinsic balance for effective disease suppression. …”
Get full text

Prevalence of Vitamin A Deficiency (VAD) with Some Associated Risk Factors among Children Aged 1 to 5 Years in Rural Maharashtra – A Community Based Cross-Sectional Study by Raghavendra NR. Swamy, Priyanka N Akahade, P Abhinaya, Arvindkumar Waghmare, Satish V Gujalwar

“…Background: Nutrition is an indispensable part of human life. Vitamin A deficiency(VAD) is the most important cause of preventable blindness in young children. …”
Get full text