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  1. 28281

    Analysis of Salivary Cytokines in Retinopathy of Prematurity by Hwa-Shiu Wu, Hsin-Chun Huang, I-Lun Chen

    Published 2025-01-01
    “…Salivary samples were collected on their first (D1) and seventh (D7) days of life, and cytokine levels were measured using the MILLPLEXMAP Human multiplex assay. Results: A total of 125 neonates were included in the study, categorized into two groups based on the severity of ROP: None to Mild and Moderate to Severe. …”
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  2. 28282

    Technical and cost efficiency analysis of irrigated onion production insight from smallholders irrigated onion farmers in north East Amhara National Regional State, Ethiopia by Kindye Ayen, Tariku Kidane, Adane Wubet

    Published 2025-01-01
    “…Onions are a popular crop in Ethiopia for human consumption and export.MethodsFor this study, 150 smallholder producers were surveyed to collect cross-sectional data. …”
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  3. 28283

    Evaluation of spatio-temporal water quality status of Jeera river, Odisha, India by Aiswarya Pati, Showkat Ahmad Mir, Archana Padhiary, Iswar Baitharu, Binata Nayak

    Published 2025-01-01
    “…Abstract Jeera River of Bargarh District, Odisha faces serious deterioration due to massive human intervention. It is particularly susceptible to degradation because it receives industrial and waste water emissions from surrounding organizations and municipal bodies. …”
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  4. 28284

    Preparation and in vitro biological evaluation of strontium doped β-tricalcium phosphate scaffolds for alveolar bone tissue regeneration by Congrui Liu, Guiyong Xiao, Zichen Wang, Mengchen Xu, Yinchuan Wang, Nan Wang, Zhenlong Sun, Xiaoyan Li, Yixin Yin

    Published 2025-01-01
    “…A range of strategies have been devised to boost the osteogenic differentiation capacity of various biomaterials. As a human trace element, strontium (Sr) plays a vital role in bone remodeling. …”
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  5. 28285

    Metabolomics and Lipidomics Reveal the Metabolic Disorders Induced by Single and Combined Exposure of Fusarium Mycotoxins in IEC-6 Cells by Xinlu Wang, Yanyang Xu, Haiqi Yu, Yushun Lu, Yongzhong Qian, Meng Wang

    Published 2025-01-01
    “…Deoxynivalenol (DON), fumonisin B<sub>1</sub> (FB<sub>1</sub>), and zearalenone (ZEN) are typical fusarium mycotoxins that occur worldwide in foodstuffs, posing significant health hazards to humans and animals. Single and combined exposure of DON, FB<sub>1</sub>, and ZEN leads to intestinal toxicity but the toxicology mechanism research is still limited. …”
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  6. 28286

    A Roadmap Draft for the Development of Marine Regenerative Medicine in I.R. Iran by Mahdi Mahmoudpour, Iraj Nabipour

    Published 2025-01-01
    “…Educating and training the next generation of human resources to provide a critical national mass of workforce for MRM; 5. …”
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  7. 28287

    Deep learning-based prediction of HER2 status and trastuzumab treatment efficacy of gastric adenocarcinoma based on morphological features by Zhida Wu, Tao Wang, Junlin Lan, Jianchao Wang, Gang Chen, Tong Tong, Hejun Zhang

    Published 2025-01-01
    “…Abstract Background First-line treatment for advanced gastric adenocarcinoma (GAC) with human epidermal growth factor receptor 2 (HER2) is trastuzumab combined with chemotherapy. …”
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  8. 28288

    Long-Term Stability and Osteogenic Activity of Recycled Polysulfone-Calcium Silicate Bone Implants In Vitro by Chi-Nan Chang, Yun-Ru Huang, Shinn-Jyh Ding

    Published 2025-01-01
    “…We evaluated the phase, morphology, weight loss, and three-point bending strength of the PSF-based composites after they were soaked in dynamic simulated body fluid (SBF) at pH levels of 7.4 and 5.0 for up to 12 months. Human mesenchymal stem cells (hMSCs) were utilized to assess the osteogenic activity of these composites. …”
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  9. 28289

    The Role of ChatGPT and AI Chatbots in Optimizing Antibiotic Therapy: A Comprehensive Narrative Review by Ninel Iacobus Antonie, Gina Gheorghe, Vlad Alexandru Ionescu, Loredana-Crista Tiucă, Camelia Cristina Diaconu

    Published 2025-01-01
    “…However, challenges such as inconsistent handling of clinical nuances, susceptibility to unsafe advice, algorithmic biases, data privacy concerns, and limited clinical validation underscore the importance of human oversight and refinement. <b>Conclusions:</b> AI chatbots have the potential to complement antibiotic stewardship efforts by promoting appropriate antibiotic use and improving patient outcomes. …”
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  10. 28290

    Modeling TB and HIV co-infections by Lih-Ing W. Roeger, Z. Feng, Carlos Castillo-Chávez

    Published 2009-08-01
    “…Tuberculosis (TB) is the leading cause of death among individuals infected with the human immunodeficiency virus (HIV). The study of the joint dynamics of HIV and TB present formidable mathematical challenges due to the fact that the models of transmission are quite distinct. …”
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  11. 28291

    Mining functional gene modules by multi-view NMF of phenome-genome association by Xu Jin, WenQian He, MingMing Liu, Lin Wang, YaoGong Zhang, YingJie Xu, Ling Ma, YaLou Huang, MaoQiang Xie

    Published 2025-01-01
    “…In the experiments on mining functionally related genes from mouse phenotype ontology and human phenotype ontology, CMNMF effectively improves clustering performance over the baseline methods. …”
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  12. 28292

    Micro-Characterization of Indoor Deposited Particles Using FTIR, SEM-EDS, and XRD Techniques: A Case Study of a University Campus, Bangladesh by Mamun Mahmud, Kazi ABM Mohiuddin

    Published 2024-03-01
    “…Abstract Micro-characterization of indoor atmospheric particles is essential for understanding atmospheric particle consequences on human health. In this study, the atmospheric particles were collected from inside the different buildings of KUET campus. …”
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  13. 28293

    Protocol for the development of a global core outcome set for the surgical treatment of differentiated thyroid cancer: a literature review and international Delphi survey by Anton F Engelsman, Romana T Netea-Maier, Christiaan F Mooij, Robin P Peeters, Menno R Vriens, A S Paul van Trotsenburg, Schelto Kruijff, Joep P M Derikx, Faridi S Jamaludin, Daniël J van de Berg, Hanneke M van Santen, Sarah C Clement, Eveline Bruinstroop, Frederik A Verburg, Angelique Seur, Els J M Nieveen van Dijkum

    Published 2025-01-01
    “…The final COS will be reported in accordance with the COS-Standards for Reporting statement.Ethics and dissemination The medical research ethics committee of the Amsterdam UMC confirmed that the Dutch Medical Research Involving Human Subjects Act (WMO) does not apply to this study and that full approval by the committee is not required. …”
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  14. 28294

    Prognostic significance of mast cell and microvascular densities in malignant peripheral nerve sheath tumor with and without neurofibromatosis type 1 by Roberto André Torres de Vasconcelos, Pedro Guimarães Coscarelli, Thyago Marsicano Vieira, Washington Silva Noguera, Davy Carlos Mendes Rapozo, Marcus André Acioly

    Published 2019-03-01
    “…Recently, the essential role of mast cells in the tumor onset of neurofibromatosis type 1 (NF1)‐associated neurofibromas and MPNSTs was confirmed in both experimental and human studies. In this study, we investigate mast cell density (MCD), microvascular density (MVD), and proliferation index (Ki‐67) in MPNST. …”
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  15. 28295

    AIM2 Mediates Inflammation-Associated Renal Damage in Hepatitis B Virus-Associated Glomerulonephritis by Regulating Caspase-1, IL-1β, and IL-18 by Junhui Zhen, Le Zhang, Jiachao Pan, Shumin Ma, Xiaojian Yu, Xiaobo Li, Shijun Chen, Wenjun Du

    Published 2014-01-01
    “…Following siRNA-mediated knockdown of AIM2 in HBV-infected and HBV-uninfected human glomerular mesangial (HGM) cells, expression of caspase-1, IL-1β, and IL-18 was detected by qRT-PCR and Western blot. …”
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  16. 28296

    Interleukin-1 Receptor-Associated Kinase 4 Deficiency in a Greek Teenager by Panagiota Karananou, Anastasia Alataki, Efimia Papadopoulou-Alataki

    Published 2020-01-01
    “…Background. Human interleukin- (IL-) 1 receptor-associated kinase 4 (IRAK-4) deficiency is a recently described primary immunodeficiency. …”
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  17. 28297

    Epigenetic age acceleration and methylation differences in IgG4-related cholangitis and primary sclerosing cholangitis by Alexandra Noble, Rodrigo Motta, Silvia Cabras, Belen Moron Flores, Jan Nowak, Aleksandra Glapa-Nowak, Alessandra Geremia, Jack Satsangi, Emma Culver

    Published 2025-01-01
    “…Epigenetic age acceleration was observed in patients with IgG4-SC, but not in those with PSC or UC. meQTL analyses to identify genetic determinants of methylation revealed a strong human leucocyte antigen (HLA) signal in both PSC and IgG4-SC (HLA-DQB2, HLA-DPA1, HLA-F and HLA-DRA). …”
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  18. 28298

    Intensification of Natural Disasters in the State of Pará and the Triggering Mechanisms Across the Eastern Amazon by Everaldo B. de Souza, Douglas B. S. Ferreira, Luciano J. S. Anjos, Alan C. Cunha, João Athaydes Silva, Eliane C. Coutinho, Adriano M. L. Sousa, Paulo J. O. P. Souza, Waleria P. Monteiro Correa, Thaiane S. Silva Dias, Alexandre M. C. do Carmo, Carlos B. B. Gutierrez, Giordani R. C. Sodré, Aline M. M. Lima, Edson J. P. Rocha, Bergson C. Moraes, Luciano P. Pezzi, Tercio Ambrizzi

    Published 2024-12-01
    “…The detailed characterization of disasters on a municipal scale is relevant in terms of the scientific contribution applied to the strategic decision-making, planning, and implementation of public policies aimed at early risk management (rather than post-disaster response), which is critical for safeguarding human well-being and strengthening the resilience of Amazonian communities vulnerable to climate change.…”
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  19. 28299

    EEG-based functional and effective connectivity patterns during emotional episodes using graph theoretical analysis by Majid Roshanaei, Hamzeh Norouzi, Julie Onton, Scott Makeig, Alireza Mohammadi

    Published 2025-01-01
    “…These findings enhance our understanding of emotional processing and have practical applications in mental health, biomarker identification, and human-computer interaction.…”
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  20. 28300

    Lipidomics-based association study reveals genomic signatures of anti-cancer qualities of pigmented rice sprouts by Rhowell Navarro Tiozon, Rhowell Navarro Tiozon, Erstelle Pasion-Uy, Saleh Alseekh, Saleh Alseekh, Kristel June D. Sartagoda, Shem Gempesaw, Joel H. G. Tolentino, Alisdair R. Fernie, Alisdair R. Fernie, Nese Sreenivasulu

    Published 2025-01-01
    “…This study offers valuable insights into the health-promoting potential of germinated rice sprouts as a rich dietary source of antioxidants beneficial to human health.…”
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