Molecular techniques for cancer diagnostics by Vimal Kishor Singh, Ramesh Chandra

“…Recent advancements in describing genetic alterations in human cancers are a tempting reason for scientists to develop more effective, personalized therapies as the next level of cancer treatment. …”
Get full text

Factors Affecting Vulnerability of Urban Space with Crisis Management Approach Case Study: Robat Karim City by Parisa Hamedani, Azita Rajabi

“…In the new age and in the third millennium, natural crises have become an inseparable reality of human life and have become one of the most important issues facing most of the world's metropolises. …”
Get full text

Isoleucine at position 137 of haemagglutinin acts as a mammalian adaptation marker of H9N2 avian influenza virus by Weiwei Ma, Chenyang Ren, Lin Shi, Bo Meng, Yali Feng, Ying Zhang

“…The H9N2 subtype of avian influenza virus (AIV) is widely distributed among poultry and wild birds and is also a threat to humans. During AIV active surveillance in Liaoning province from 2015 to 2016, we identified 10 H9N2 strains exhibiting different lethality to chick embryos. …”
Get full text

Profiling bacterial communities of irrigation water and leafy green vegetables produced by small-scale farms and sold in informal settlements in South Africa by D. M. Kgoale, J. K. Gokul, S. Duvenage, E. M. Du Plessis, L. Korsten

“…These findings suggest that the edible plant microbiome can play an important role as transient contributor to the human gut and has the potential to affect overall health.…”
Get full text

Candida albicans Fungaemia following Traumatic Urethral Catheterisation in a Paraplegic Patient with Diabetes Mellitus and Candiduria Treated by Caspofungin by Subramanian Vaidyanathan, Bakul Soni, Peter Hughes, Gordon Ramage, Leighann Sherry, Gurpreet Singh, Paul Mansour

“…This patient was prescribed human soluble insulin and caspofungin 70 mg followed by 50 mg daily intravenously. …”
Get full text

Increased birth rank of homosexual males: disentangling the older brother effect and sexual antagonism hypothesis by Raymond, Michel, Turek, Daniel, Durand, Valérie, Nila, Sarah, Suryobroto, Bambang, Vadez, Julien, Barthes, Julien, Apostolou, Menelaos, Crochet, Pierre-André

“…However, there is no consensus on whether both FBOE and AE are present in human populations, or if only one of these mechanisms is at play with its effect mimicking the signature of the other mechanism. …”
Get full text

Anthelmintic activity of 1,10-phenanthroline-5,6-dione-based metallodrugs by Maria E. Cirino, Thainá R. Teixeira, Alessandro M. H. Silva, Ana C. C. Borges, Lucas Fukui-Silva, Luis G. Wagner, Christiane Fernandes, Malachy McCann, André L. S. Santos, Josué de Moraes

“…This study investigates the potential antiparasitic activity of 1,10-phenanthroline-5,6-dione (phendione) and its metal complexes, [Cu(phendione)3](ClO4)2.8H2O and [Ag(phendione)2](ClO4), against Schistosoma mansoni, the causative agent of intestinal schistosomiasis, and Angiostrongylus cantonensis, responsible for eosinophilic meningitis in humans. Additionally, the compounds were tested on Caenorhabditis elegans, a model organism for drug discovery. …”
Get full text

Pleural Mesothelial Cells-Induced Monocytes to the Pleural Cavity through the Effect of C3 Lytic Products in Tuberculous Pleural Effusion by Lisha Luo, Juntao Feng, Shuanglinzi Deng, Xinyue Hu, Bingrong Zhao, Wei Tang, Xiaozhao Li

“…Tuberculous protein Mpt64 and anaphylatoxin C3a could significantly promote CXCL12 production in human PMCs isolated from TPE. C3b-CR1, C3d-CR3, and CXCL12-CXCR4 were colocalized in PMCs and monocytes from TPE. …”
Get full text

Generative AI in Higher Education: Balancing Innovation and Integrity by Nigel J. Francis, Sue Jones, David P. Smith

“…Our analysis is framed within pedagogical theories, including social constructivism and competency-based learning, highlighting the importance of balancing human expertise and AI capabilities. We also address broader ethical concerns associated with GenAI, such as the risks of bias, the digital divide, and the environmental impact of AI technologies. …”
Get full text

Establishment of a Novel Model for Anticancer Drug Resistance in Three-Dimensional Primary Culture of Tumor Microenvironment by Tatsuya Usui, Masashi Sakurai, Shuhei Enjoji, Hideyoshi Kawasaki, Koji Umata, Takashi Ohama, Nobuyuki Fujiwara, Ryotaro Yabe, Shunya Tsuji, Hideyuki Yamawaki, Shoichi Hazama, Hiroko Takenouchi, Masao Nakajima, Ryouichi Tsunedomi, Nobuaki Suzuki, Hiroaki Nagano, Koichi Sato

“…Here, we developed an ALI organoid model from normal and tumor colorectal tissues of human patients. Both organoids were successfully generated and showed cystic structures containing an epithelial layer and surrounding mesenchymal stromal cells. …”
Get full text

Effectiveness of Clinical Training in Influencing the Outcome of Visual Inspection with Acetic Acid in Selected Facilities at a County in Kenya by Evah Maina, Abednego Ongeso, Nancy Maingi

“…Background: Cervical cancer remains a major health concern in developing countries, primarily due to the presence of human papillomavirus (HPV) types 16 and 18. Visual Inspection with Acetic Acid (VIA) is a common and affordable screening method, yet its effectiveness is closely tied to the skills and competency of healthcare providers. …”
Get full text

Adopting Sustainability: The Role of Motivation and Intention to Forming Green Behavior by Khrisna Vembri Yudanto, Fanny Martdianty

“…Conclusion: This research has deep implications in enriching the perspective of implementing environmentally friendly behavior in the business environment and strengthening managerial management by providing comprehensive considerations for management in realizing environmentally friendly business processes as a whole, especially in the field of human resource management. Originality/value (State of the art): This research fills the empirical gap by providing research in the energy sector and increasing the number of samples used from previous research. …”
Get full text

Adaptation of the sulfophosphovanillin method of analysis of total lipids for various biological objects as exemplified by <i>Drosophila melanogaster</i> by M. A. Eremina, N. E. Gruntenko

“…In recent decades the model object Drosophila melanogaster has been actively used in the study of the fundamental issues of lipid metabolism and its disorders, including obesity, as well as in the search for therapeutic goals for the treatment of metabolic disorders in humans. Quick and accurate quantification of lipid content is an important step in solving these problems. …”
Get full text

Peripheral T-Cell Lymphoma with Aberrant Expression of CD19, CD20, and CD79a: Case Report and Literature Review by Rahul G. Matnani, Rachel L. Stewart, Joseph Pulliam, Chester D. Jennings, Melissa Kesler

“…The neoplastic cells were negative for Epstein-Barr virus (EBV) or Human Herpes Virus 8 (HHV-8). At the time of diagnosis, the PET scan demonstrated hypermetabolic neoplastic cells involving the left axilla, bilateral internal jugular areas, mediastinum, right hilum, bilateral lungs, and spleen. …”
Get full text

Challenges in safe environmental applications of biochar: identifying risks and unintended consequence by Mingying Dong, Mengyuan Jiang, Lizhi He, Zirun Zhang, Williamson Gustave, Meththika Vithanage, Nabeel Khan Niazi, Bo Chen, Xiaokai Zhang, Hailong Wang, Feng He

“…Furthermore, it provides a thorough overview of the adverse effects on animals, plants, microorganisms, and human health, elucidating the mechanisms of pollutant release, aging, and nano-effects from environmental geochemical processes involving biochar. …”
Get full text

Unraveling the degradation mechanism of multiple pyrethroid insecticides by Pseudomonas aeruginosa and its environmental bioremediation potential by Hui Liu, Wen-Juan Chen, Zeling Xu, Shao-Fang Chen, Haoran Song, Yaohua Huang, Kalpana Bhatt, Sandhya Mishra, Mohamed A. Ghorab, Lian-Hui Zhang, Shaohua Chen

“…Extensive use of pyrethroid insecticides poses significant risks to both ecological ecosystems and human beings. Herein, Pseudomonas aeruginosa PAO1 exhibited exceptional degradation capabilities towards a range of pyrethroid family insecticides including etofenprox, bifenthrin, tetramethrin, D-cypermethrin, allethrin, and permethrin, with a degradation efficiency reaching over 84 % within 36 h (50 mg·L-1). …”
Get full text

Efficacy and Interindividual Variability in Motor-Cortex Plasticity following Anodal tDCS and Paired-Associative Stimulation by Wolfgang Strube, Tilmann Bunse, Berend Malchow, Alkomiet Hasan

“…We aimed to compare the efficacy and response variability of two LTP-inducing stimulation protocols in the human motor cortex: anodal transcranial direct current stimulation (a-tDCS) and paired-associative stimulation (PAS25). …”
Get full text

Pancasila in the Context of Indonesian Legal Reform: A Critical Evaluation and International Debate by Elfrida Herawati Siregar, Cahyo Budi Utomo, Muh Sholeh

“…Through a doctrinal and socio-legal analysis, the study examines the compatibility of Pancasila with contemporary global legal norms, including human rights, environmental law, and economic governance. …”
Get full text

Navigating challenges, solutions and requirements in the provision of trauma care in conflict settings by humanitarian actors: a scoping literature review by Nikolaos Markou-Pappas, Luca Ragazzoni, Claudia Truppa, Flavio Salio, Francesco Barone-Adesi, Hamdi Lamine

“…Abstract Background The evolving nature of irregular warfare and the increasingly frequent violations of human rights law and international humanitarian law pose unique challenges for humanitarian actors delivering trauma care in conflict settings. …”
Get full text

Identification of fatty acid anabolism patterns to predict prognosis and immunotherapy response in gastric cancer by Weijie Sun, Yanhong Xia, Feifan Jin, Jinghao Cao, Gaoping Wu, Keyi Li, Yanhua Yu, Yunyi Wu, Gaoqi Ye, Ke Xu, Dengpan Liu, Weidong Jin

“…Fatty acid is one of the main nutrients of human beings, which is closely related to diabetes, hypertension and other diseases. …”
Get full text