Rectal mucosal inflammation, microbiome, and wound healing in men who have sex with men who engage in receptive anal intercourse by Vanessa E. Van Doren, Cassie G. Ackerley, Robert A. Arthur, Phillip M. Murray, S. Abigail Smith, Yi-Juan Hu, Colleen F. Kelley

“…This work is the first experimental study of rectal mucosal injury and the immune environment in healthy humans and provides a more nuanced understanding of rectal mucosal inflammation after injury, which can inform our understanding of HIV transmission.…”
Get full text

Adsorption and Desorption Characteristics and Purification of Isoflavones from Crude Soybean Extract Using Macroporous Resins by Thi Ngoc Thu Tran, Xuan Vung Bui, Nguyen Thi Truc Loan, Nguyen Huu Thuan Anh, Truong Dang Le, Thi Minh Hanh Truong

“…Isoflavones in soybean have been well-known with many health-promoting effects on humans. This study aimed to purify isoflavones from the crude soybean extract by the static adsorption/desorption process on macroporous resins. …”
Get full text

Internet of things enabled smart agriculture: Current status, latest advancements, challenges and countermeasures by Navod Neranjan Thilakarathne, Muhammad Saifullah Abu Bakar, Pg Emeroylariffion Abas, Hayati Yassin

“…It is no wonder that agriculture plays a vital role in the development of some countries when their economies rely on agricultural activities and the production of food for human survival. Owing to the ever-increasing world population, estimated at 7.9 billion in 2022, feeding this number of people has become a concern due to the current rate of agricultural food production subjected to various reasons. …”
Get full text

Detention of a person committed a criminal offence: criminal procedural and forensic characteristics by V. G. Drozd

“…The practice of using administrative detention for the purposes of criminal proceedings is unacceptable, as the European Court of Human Rights has repeatedly pointed out. Prospect for the further research is the need to analyse the measures of restraint used during the pre-trial investigation of criminal offences, as well as to clarify the existential content and essence of the relevant institution, and its importance for the criminal justice system in general.…”
Get full text

Differential Effects of Angelicin Analogues on NF-κB Activity and IL-8 Gene Expression in Cystic Fibrosis IB3-1 Cells by Ilaria Lampronti, Maria Giulia Manzione, Gianni Sacchetti, Davide Ferrari, Susanna Spisani, Valentino Bezzerri, Alessia Finotti, Monica Borgatti, Maria Cristina Dechecchi, Giorgia Miolo, Giovanni Marzaro, Giulio Cabrini, Roberto Gambari, Adriana Chilin

“…These findings encouraged us to analyze new synthetic analogues of TMA in order to evaluate their biological activities on human bronchial epithelial CF IB3-1 cells and to find more potent anti-NF-κB agents exhibiting only minor antiproliferative effects. …”
Get full text

Extreme Environment Streptomyces: Potential Sources for New Antibacterial and Anticancer Drug Leads? by Periyasamy Sivalingam, Kui Hong, John Pote, Kandasamy Prabakar

“…Conversely, cancer is a growing complex human disease that demands new drugs with no or fewer side effects. …”
Get full text

HTLV-1 bZIP factor induces T-cell lymphoma and systemic inflammation in vivo. by Yorifumi Satou, Jun-Ichirou Yasunaga, Tiejun Zhao, Mika Yoshida, Paola Miyazato, Ken Takai, Kei Shimizu, Koichi Ohshima, Patrick L Green, Naganari Ohkura, Tomoyuki Yamaguchi, Masahiro Ono, Shimon Sakaguchi, Masao Matsuoka

“…Human T-cell leukemia virus type 1 (HTLV-1) is the causal agent of a neoplastic disease of CD4+ T cells, adult T-cell leukemia (ATL), and inflammatory diseases including HTLV-1 associated myelopathy/tropical spastic paraparesis, dermatitis, and inflammatory lung diseases. …”
Get full text

The Studies of Chlorogenic Acid Antitumor Mechanism by Gene Chip Detection: The Immune Pathway Gene Expression by Tian Yi Kang, Hua Rong Yang, Jie Zhang, Dan Li, Jie Lin, Li Wang, XiaoPing Xu

“…Persistently increasing incident of cancer in human beings has served to emphasize the importance of studies on mechanism of antitumor substances. …”
Get full text

Natural antifibrosis potential of anthocyanin in Ipomoea batatas against Transforming Growth Factor beta Type II receptor by in silico ADMET and molecular docking study by Evi Lusiana, Ernawati Sinaga, Zen Hafy, Debby Handayati Harahap, Ramzi Amin, Irsan Saleh

“…Purple sweet potato (Ipomoea batatas) are known to have bioactive anthocyanin compounds with numerous human therapeutic benefits. Anthocyanins derived from I. batatas can suppress the action of Transforming Growth Factor beta Type II Receptor (TGFβRII) to prevent fibrosis progression. …”
Get full text

Navigating a Climate in Crisis through a Biomimetic Epistemology by Elizabeth McCormick, David Thaddeus

“… We have entered a geological epoch where environmental change is driven primarily by human activity. The technology-centric approach to sustainable development as the dominant model of innovation in industrialized countries has led to expansive ecological degradation. …”
Get full text

Single-Cell RNA Sequencing Reveals Macrophage Dynamics During MASH in <i>Leptin</i>-Deficient Rats by Xiaoming Xin, Yaohua Ni, Jing Wang, Fenglin Wu, Meichen Liu, Lingjuan Wu, Jiaxing Dai, Chenglin Wu, Xiaolei Song, Wang Zhang, Guangrui Yang, Ruling Shen, Xianmin Zhu

“…Macrophages play important roles in metabolic dysfunction-associated steatohepatitis (MASH), an advanced and inflammatory stage of metabolic dysfunction-associated steatotic liver disease (MASLD). In humans and mice, the cellular heterogeneity and diverse function of hepatic macrophages in MASH have been investigated by single cell RNA sequencing (scRNA-seq). …”
Get full text

Temporal drivers of abundance and community structure of scyphozoan jellyfish in tropical coastal waters by Wan Mohd Syazwan, Amy Yee-Hui Then, Ving Ching Chong, Mohammed Rizman-Idid

“…Population blooms of scyphozoan jellyfish in tropical shallow water regions can fuel localized fisheries but also negatively impact human welfare. However, there is a lack of baseline ecological data regarding the scyphozoans in the region, which could be used to manage a fast-growing fishery and mitigate potential impacts. …”
Get full text

Probiotic Characterization of Lactic Acid Bacteria from Donkey Feces in China by Yanqiu Wu, Shousong Yue, Jinhui Yu, Fei Bian, Gao Chen, Yan Zhang

“…Probiotics are beneficial to humans and animals and often used for regulating immunity, intestinal microbiota balance, and animal growth performance. …”
Get full text

Inhibition of Horseradish Peroxidase Activity by Boroxine Derivative, Dipotassium-trioxohydroxytetrafluorotriborate K2[B3O3F4OH] by Jelena Ostojic, Safija Herenda, Semira Galijasevic, Borivoj Galic, Mladen Milos

“…Recently research shows that horseradish peroxidase, HRP, when combined with other compounds, is highly reactive toward different human tumour cells and that better understanding of catalytic mechanism and inhibition HPR could lead to a new targeted cancer therapy. …”
Get full text

The Effect of a Training Program (Retention) on the Clinical Competence, Self-Efficacy, and Occupational Stress of Undergraduate Students of Anesthesia: The Transition from Student... by Ali Khalafi, Shahla Assadi Hovyzian, Nooshin Sarvi-Sarmeydani

“… Background: Transferring students from university to the workplace due to facing many challenging and stressful factors is one of the important stages that, if the educational authorities do not pay attention, it leads to low efficiency and an increase in the number of resignations from the workplace, which leads to financial and human losses for the system. Purpose: Investigating the effect of a training program on the clinical competence, self-efficacy, and occupational stress of Anesthesiology undergraduate students, in their transition from the studenthood to the clinical workforce. …”
Get full text

Assessment of foot type and comparison of anthropometric foot dimension between foot types of Indian population: A pilot study by Rajib Jana, Ayan Maity, Sugata Das Kumar, Madhusudan Pal

“…Background: Human foot morphology is essential for enhancing the fit and comfort of foot-related products in fields like orthopedics, orthotic design, and sports sciences. …”
Get full text

From fitness trackers to medical devices: wearable technologies by Zhi Zhou

“…The multiple possibilities they offer have spread towards previously hard-to-imagine fields, like e-health or human physiological monitoring. An application has been developed for its usage in scenarios where data collection is applied to smart spaces, aiming at its usage in firefighting and sports. …”
Get full text

Image-guided Control of Transgene Expression Based on Local Hyperthermia by E. Guilhon, B. Quesson, F. Moraud-Gaudry, H. de Verneuil, P. Canioni, R. Salomir, P. Voisin, C. T. W. Moonen

“…A stable modified C6 glioma cell line was used carrying a fused gene coding for thymidine kinase (TK) and green fluorescent protein (GFP) under control of the human heat-shock protein 70 (HSP70) promoter. In vitro studies showed strong induction of the TK-GFP gene expression upon heat shock under various conditions and localization of the protein product in the nucleus. …”
Get full text

Multiband Planar Inverted-F Antenna with Independent Operating Bands Control for Mobile Handset Applications by Mustapha El Halaoui, Abdelmoumen Kaabal, Hassan Asselman, Saida Ahyoud, Adel Asselman

“…The distribution of specific absorption rate for both European and American standards for each operating band and at various distances between the antenna and the human head is also studied.…”
Get full text

The Efficiency of Direct Maturation: the Comparison of Two hiPSC Differentiation Approaches into Motor Neurons by Catherine Schaefers, Simone Rothmiller, Horst Thiermann, Theo Rein, Annette Schmidt

“…Motor neurons (MNs) derived from human-induced pluripotent stem cells (hiPSC) hold great potential for the treatment of various motor neurodegenerative diseases as transplantations with a low-risk of rejection are made possible. …”
Get full text