Effectiveness of three biomimetic remineralization procedures in artificial caries-affected dentin – an in-vitro pilot study by Rosário Costa, Sofia Arantes-Oliveira, Lisete Fernandes, Fábio G. Figueiras, João Cardoso Ferreira, Paulo Ribeiro de Melo

“…Methods: Seventy-two specimens of healthy human dentin were divided into twelve groups. Half of each group’s samples were analyzed using field-emission gun environmental scanning electron microscope/energy dispersive X-ray, while the other half were analyzed by X-ray diffraction and micro-Raman spectroscopy. …”
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Isolation and Characterisation of Mesenchymal Stem Cells from Rat Bone Marrow and the Endosteal Niche: A Comparative Study by Norhayati Yusop, Paul Battersby, Amr Alraies, Alastair J. Sloan, Ryan Moseley, Rachel J. Waddington

“…Such findings support further comparisons of human CB-MSCs and BM-MSCs, facilitating selection of optimal MSC populations for regenerative medicine purposes.…”
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Modern possibilities of sodium hyaluronate in tear substitutive therapy of patients with “dry eye” syndrome by V.V. Brzheskiy, V.Yu. Popov

“…In a number of experimental studies, the efficacy and safety of the Vismed line is proved: in vitro — on the culture of epithelial cells of the human conjunctiva, in vivo — on the model of traumatic corneal erosion in rabbits. …”
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Differentially Expressed MicroRNAs in the Development of Early Diabetic Retinopathy by Qiaoyun Gong, Jia’nan Xie, Yang Liu, Ying Li, Guanfang Su

“…Because microRNAs (miRNAs) represent effective DR therapeutic targets, we identified aberrantly expressed miRNAs associated with cellular dysfunction in early DR and detected their potential targets. We exposed human retinal endothelial cells (HRECs) and a cell line of retinal pigment epithelial (RPE) cells to high glucose (25 mmol/L, 1–7 days) to mimic DR progression and used streptozotocin-injected rats (4–8 weeks) for an in vivo diabetes model. …”
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Molecular Detection of <i>Rickettsia</i> spp. and Other Tick-Borne Pathogens in Ticks from a Nature Reserve: Implications for Zoonotic Transmission by Santina Di Bella, Valeria Blanda, Silvia Scibetta, Ilenia Giacchino, Antonino Gentile, Giuseppina Chiarenza, Vincenza Cannella, Giovanni Provinzano, Francesca Grippi, Annalisa Guercio

“…Ticks are a major concern for both animal and human health, as they are primary vectors of infectious pathogens. …”
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Multimodal heterogeneous graph fusion for automated obstructive sleep apnea-hypopnea syndrome diagnosis by Haoyu Wang, Xihe Qiu, Bin Li, Xiaoyu Tan, Jingjing Huang

“…This framework constructs two types of graph representations: physical space graphs, which map the spatial layout of sensors on the human body, and process knowledge graphs which detail the physiological relationships among breathing patterns, oxygen saturation, and vital signals. …”
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CFP-AL: Combining Model Features and Prediction for Active Learning in Sentence Classification by Keuntae Kim, Yong Suk Choi

“…Particularly, obtaining high-quality labeled datasets for supervised learning requires human annotation, and an effective active learning strategy can greatly reduce annotation costs. …”
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Development of Collagen-Based 3D Matrix for Gastrointestinal Tract-Derived Organoid Culture by Joo Hyun Jee, Dong Hyeon Lee, Jisu Ko, Soojung Hahn, Sang Yun Jeong, Han Kyung Kim, Enoch Park, Seon Young Choi, Sukin Jeong, Joong Woon Lee, Han-Jun Cho, Min-Soo Kwon, Jongman Yoo

“…Mouse small intestine–derived organoids, stomach-derived organoids, and human colon–derived organoids were also cultured, all of which were successfully grown in the collagen-based matrix and had similar properties compared to those cultured in Matrigel. …”
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Understanding Indigenous knowledge of conservation and stewardship before implementing co-production with Western methodologies in resource management by Stafford Maracle, Jennifer Maracle, Stephen Lougheed

“… In the face of an increasing global human popula­tion and multiple anthropogenic environmental stressors including climate change, the limitations of relying solely on Western science and ap­proaches to mitigating impacts, conserving bio­diversity, and managing resources sustainably is apparent. …”
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IFN Regulatory Factor 1 Mediates Macrophage Pyroptosis Induced by Oxidized Low-Density Lipoprotein in Patients with Acute Coronary Syndrome by Min Guo, Rui Yan, Hongmei Yao, Liqin Duan, Meng Sun, Zheng Xue, Yongping Jia

“…The expression of IRF-1 in human PBMC-derived macrophages was analyzed. Then, overexpression and inhibition of IRF-1 was performed in macrophages from patients with ACS to explore the possible role and mechanism of IRF-1 involvement in macrophage pyroptosis. …”
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Mesenchymal stem cell-derived extracellular vesicles enriched with miR-124 exhibit anti-inflammatory effects in collagen-induced arthritis by Guo Zhonghua, He Mengyuan, Shi Dongliang, Zhang Zhongbo, Wang Lisha, Ren Bowen, Wang Yunfei, Wang Junjie, Yang Shaoxiang, Yu Hongchao

“…This study investigated the anti-inflammatory effects of human umbilical cord-derived MSC (hUCSC)-EVs overexpressing miR-124 in collagen-induced arthritis (CIA). hUCSCs were transfected with miR-124, and hUCSC-EVs were isolated and characterized. …”
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AutoMEX: Streamlining material extrusion with AI agents powered by large language models and knowledge graphs by Haolin Fan, Junlin Huang, Jilong Xu, Yifei Zhou, Jerry Ying Hsi Fuh, Wen Feng Lu, Bingbing Li

“…AutoMEX utilizes a knowledge graph (KG) derived from the scientific literature to enable LLMs to provide expert recommendations on material selection, process parameters, and design considerations, thereby improving accessibility and efficiency. With minimal human intervention, the framework encompasses a complete workflow, including CAD model generation, printing parameter recommendation, slicing, and machine operation. …”
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A novel Complex q-rung orthopair fuzzy Yager aggregation operators and their applications in environmental engineering by Jabbar Ahmmad, Tahir Mahmood, Dragan Pamucar, Hafiz Muhammad Waqas

“…Improving human health and comfort in buildings requires efficient temperature regulation. …”
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Adiabatic Fixed-Bed Gasification of Colombian Coffee Husk Using Air-Steam Blends for Partial Oxidation by Javier Bonilla, Gerardo Gordillo

“…The increasing energy consumption, mostly supplied by fossil fuels, has motivated the research and development of alternative fuel technologies to decrease the humanity’s dependence on fossil fuels, which leads to pollution of natural sources. …”
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Ameliorative effect of liprotide-encapsulated vitamin D3 on blood glucose, calcium homeostasis, and vitamin D level in a vitamin D and calcium deficient rat model by Gemala Anjani, Reza Achmad Maulana, Sylvia Rahmi Putri, Faizah Fulyani, Ahmad Syauqy, Diana Nur Afifah, Fitriyono Ayustaningwarno, Refani Alycia Kusuma, Zulfatul Masruroh

“…Vitamin D3, recognized for its higher bioavailability and direct cell utilization, plays a vital role in the human body. Applying β-lactoglobulin with oleic acid (β-Lg-AO) as an encapsulating agent is anticipated to protect and enhance the transport of vitamin D3 to the gastrointestinal system. …”
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Widely Targeted Metabolomics Analysis Reveals Key Quality-Related Metabolites in Kernels of Sweet Corn by Ruichun Yang, Yunfeng Li, Yuanyuan Zhang, Jun Huang, Junjie Liu, Zimei Lin, Qinqin Yu, Aimin Wu, Bo Wang

“…And the essential amino acids for the human body, methionine and threonine, were highly accumulated in the high-quality cultivar. …”
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Evaluation of the Drug-Resistant Tuberculosis (DR-TB) management component under the National Tuberculosis Elimination Program (NTEP) in Kerala, India, 2021-22 by Raman Swathy Vaman, Madhanraj Kalyanasundaram, Malu Mohan, Narayana Pradeepa, Manoj V. Murhekar

“…The favorable treatment outcome was 80% Interviews revealed poor readiness and motivation from the private sector for screening, contextual barriers in human resource availability, transportation, and financial barriers to the beneficiary despite providing financial benefits. …”
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Magnolol induces cell death through PI3K/Akt‐mediated epigenetic modifications boosting treatment of BRAF‐ and NRAS‐mutant melanoma by Abdullah Al Emran, Brinda Reddy Chinna Chowdary, Farzana Ahmed, Heinz Hammerlindl, Antje Huefner, Nikolas K. Haass, Wolfgang Schuehly, Helmut Schaider

“…Here, we show that magnolol, a constituent of Magnolia officinalis, induced G1 arrest, apoptosis and cell death in BRAF‐ and NRAS‐mutant melanoma cells at low concentration, with no effect in BRAF‐ and NRAS wild‐type melanoma cells and human keratinocytes. This was confirmed in a 3D spheroid model. …”
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United Nations - African Union Cooperation In Conflict Prevention, Peacekeeping and Peacebuildin by L. I. Romadan, V. A. Shagalov

“…Through its agencies of ensuring peace and security the African Union is making significant contribution to strengthening stability and promotion of democracy and human rights in Africa. In the beginning of the article authors make a review of the level of security on the African continent and stress the sharpest conflict zones. …”
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Development and Implementation of an IoT-Based Early Flood Detection and Monitoring System Utilizing Time Series Forecasting for Real-Time Alerts in Resource-Constrained Environmen... by Nik Nor Muhammad Saifudin Nik Mohd Kamal, Ahmad Anwar Zainuddin, Abu Ubaidah Shamsudin, Muhamad Syariff Sapuan, Muhammad Hazim Amin Samsudin, Mohammad Adam Haikal Zulkfli

“…Traditional flood monitoring systems have severe limitations, including reliance on human data gathering, a lack of real-time capabilities, expensive prices, and slow response times, particularly in developing countries. …”
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