Instance maps as an organising concept for complex experimental workflows as demonstrated for (nano)material safety research by Benjamin Punz, Maja Brajnik, Joh Dokler, Jaleesia D. Amos, Litty Johnson, Katie Reilly, Anastasios G. Papadiamantis, Amaia Green Etxabe, Lee Walker, Diego S. T. Martinez, Steffi Friedrichs, Klaus M. Weltring, Nazende Günday-Türeli, Claus Svendsen, Christine Ogilvie Hendren, Mark R. Wiesner, Martin Himly, Iseult Lynch, Thomas E. Exner

“…Application of the InstanceMaps tool (described herein) to research workflows of increasing complexity is presented to demonstrate its utility, starting from (i) documentation of a nanomaterial’s synthesis, functionalisation, and characterisation, over (ii) assessment of a nanomaterial’s transformations in complex media, (iii) description of the culturing of ecotoxicity model organisms Daphnia magna and their use in standardised tests for nanomaterials ecotoxicity assessment, and (iv) visualisation of complex workflows in human immunotoxicity assessment using cell lines and primary cellular models, to (v) the use of the instance map approach for the coordination of materials and data flows in complex multipartner collaborative projects and for the demonstration of case studies. …”
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Cluster analysis of social determinants of health and HIV/AIDS knowledge among Peruvian youths using Kohonen’s self-organized maps: a data-exploration study based on a Demographic... by Alejandro Aybar-Flores, Alvaro Talavera, Elizabeth Espinoza-Portilla

“…Background Human immunodeficiency virus (HIV) and acquired immunodeficiency syndrome (AIDS) have evolved into a global development burden, with nearly 40 million infections and 25 million deaths. …”
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Experimental study of the effects of siestas on the nocturnal sleep quality and thermal comfort levels under thermoneutral environment in summer by Huili Yu, Xue Zhao, Liping Chen, Xiaohui Tian, Shimin Liang, Songtao Hu

“…It has been determined that siestas could potentially have both mental and physical influences on the human body. However, the effects of siestas on the nocturnal sleep quality and thermal comfort levels under thermoneutral environment had not yet been examined in detail. …”
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Hyalomma aegyptium: Observed global distribution, imported specimens, preferred hosts and vector competence by Franz Rubel

“…., 4.0% mammals (mainly hedgehogs and hares), 1.7% humans, 0.9% lizards and 0.5% birds. If only tortoise hosts are considered, these are 92.6% Testudo graeca, 3.8% Testudo hermanni, 2.8% Testudo horsfieldii and 0.8% Testudo marginata. …”
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Association between changes in genital immune markers and vaginal microbiome transitions in bacterial vaginosis by Philipp Foessleitner, Briah Cooley Demidkina, Wafae El-Arar, Miles Goldenberg, Meena Murthy, Agnes Bergerat, Ofri Bar, Douglas S. Kwon, Caroline M. Mitchell

“…Abstract Bacterial vaginosis (BV), characterized by an imbalance in the vaginal microbiota, is a prevalent condition among women of reproductive age and a risk factor for human immunodeficiency virus, sexually transmitted infections, and preterm birth. …”
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Investigation of the Pulmonary Artery Hypertension Using an Ad Hoc OpenFOAM CFD Solver by Francesco Duronio, Paola Marchetti

“…The outcomes of this work contribute to enlarging the knowledge of the blood flow characteristics in the human pulmonary artery, revealing substantial differences between the two clinical scenarios investigated and highlighting how arterial hypertension drastically changes the blood flow. …”
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Assessment of Hepatic Mineral Composition in Sheep, Cattle, Chicken, and Fish in Erbil City, Kurdistan Region-Iraq by Abdulqader Ahmed Hussein, Samad S. Omer, Iman S. Ali, Bnar F. Suleiman

“…Therefore, it can be concluded that there are problems on animal and human health (due to high concentration of Pb and Ni) would be raised at present from the consumption of ovine, bovine, checkin, and fish slaughtered from the city of Erbil. …”
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Mahogany seeds extract showed potential immunomodulator by in-silico and in vivo testing by Yati Sumiyati, Alessandro Gunady, Perwira Tua, Warni Warni, Heppy Novia, Emilda

“…Environmental disturbances such as climate change affect human health both infectious and non-communicable disease. …”
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Characterization of Chromatin Structure-associated Histone Modifications in Breast Cancer Cells by Chang Pyo Hong, Moon Kyung Choe, Tae-Young Roh

“…To understand the relationship between histone modifications and regulatory elements in breast cancer cells, we compared our chromatin immunoprecipitation sequencing (ChIP-Seq) histone modification patterns for histone H3K4me1, H3K4me3, H3K9/16ac, and H3K27me3 in MCF-7 cells with publicly available formaldehyde-assisted isolation of regulatory elements (FAIRE)-chip signals in human chromosomes 8, 11, and 12, identified by a method called FAIRE. …”
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PROLIFERATION AND APOPTOSIS IN RAT MODELS OF ORAL SQUAMOUS CELL CARCINOMA INDUCED BY CAPSAICIN EXTRACT NANOPARTICLE GEL by Pratiwi Nur Widyaningsih, Fitri Aniowati, Cantika Nadrotan Naim, Nova Dwi Anggraeni

“…Capsaicin, a pungent phytochemical in red peppers, exhibits both anti-proliferative and potential pro-cancer effects on human cancer cell lines. Purpose: Determine the proliferation and apoptosis between five groups of rats induced OSCC. …”
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Reinforcement Learning-Based Sequential Control Policy for Multiple Peg-in-Hole Assembly by Xinyu Liu, Chao Zeng, Chenguang Yang, Jianwei Zhang

“…This approach introduces human knowledge to manage intermediate states, such as lifting height and aligning direction, thereby enabling flexible deployment across various scenarios. …”
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Retrieval of NO2 Columns by Exploiting MAX-DOAS Observations and Comparison with OMI and TROPOMI Data during the Time Period of 2015–2019 by Ahmad Iqbal, Naveed Ahmad, Hassan Mohy ud Din, Michel Van Roozendael, Muhammad Shehzaib Anjum, Muhammad Zeeshan Ali Khan, Muhammad Fahim Khokhar

“…Exposure to high concentrations of NO2 has been reported to cause various health issues in humans. This study presents an intercomparison of NO2 retrieval settings using the Differential Optical Absorption Spectroscopy (DOAS) and based on the literature published over the last 20 years. …”
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The effect of light-emitting diode-mediated photobiomodulation therapy on orthodontic tooth movement: A literature review by Rashin Bahrami, Nariman Nikparto, Fateme Gharibpour, Maryam Pourhajibagher, Abbas Bahador

“…Five studies were included in the review, comprising two animal studies (ages 10 and 12 weeks) and three human studies (ages ranging from 15 to 17 years). …”
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Effects of endocrine disrupting chemicals, blood metabolome, and epigenetics on breast cancer risk: A multi-dimensional mendelian randomization study by Ningning Song, Xinquan Xi, Kuan Yang, Chongzhe Pei, Lingzhou Zhao

“…This study uses MR to investigate the effects of three types of EDCs, including bisphenols, parabens, and phthalates, on the risk of overall breast cancer and its subtypes—Luminal A, Luminal B, triple negative, human epidermal growth factor receptor 2-enriched, and estrogen receptor-positive/negative. …”
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Zika, a Mosquito-Transmitted Virus by L. Phil Lounibos, Barry W. Alto, Nathan D. Burkett-Cadena, Cynthia C. Lord, Chelsea T. Smartt, C. Roxanne Rutledge Connelly, Jorge R. Rey

“…In its native range in West Africa and Uganda, the Zika virus stays in the forest for the most part, and human infections are considered incidental and medically inconsequential. …”
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A sterol panel for rare lipid disorders: sitosterolemia, cerebrotendinous xanthomatosis and Smith-Lemli-Opitz syndrome by Alexander Bauer Westbye, Lili L. Dizdarevic, Sandra R. Dahl, Emil Andreas Asprusten, Yngve Thomas Bliksrud, Anita Lövgren Sandblom, Ulf Diczfalusy, Per M. Thorsby, Kjetil Retterstøl

“…A simple and rapid method to extract free sterols from human serum and quantitate their concentration using isotope-dilution liquid chromatography-tandem mass spectrometry (LC-MS/MS) without derivatization was developed. …”
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Comparing acute versus AIDS ART initiation on HIV-1 integration sites and clonal expansion by Jun Wang, Nan Xiao, Zhengnong Zhu, Haiyan Qiao, Fang Zhao, Lukun Zhang, Jizhou Gou, Mengji Lu, Yun He, Hongzhou Lu, Qian Li

“…Overall, we introduced a sequencing method to assess provirus size in human peripheral blood and identified the widespread presence of monoclonal distribution of UIS in AIDS-ART group after long-term treatment. …”
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The Ne Bis In Idem Principle in Tax Law: European and Italian Frameworks by Stefania Lotito Fedele

“…Moreover, it has become a fundamental right enshrined in the European Convention on Human Rights and the Charter of Fundamental Rights of the EU. …”
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Removal of Antibiotics from Real Hospital Wastewater by Cold Plasma Technique by Phuong Thi Thanh Nguyen, Hieu Trung Nguyen, Uyen Nhat Phuoc Tran, Ha Manh Bui

“…Hospital wastewater contains a complex mixture of bioactive substances and microorganisms that are deleterious to humans and aquatic animals. In this study, four antibiotics, namely, ofloxacin, ciprofloxacin, cefuroxime, and amoxicillin, respectively, from the wastewater of seven hospitals in Ho Chi Minh City, Vietnam, were monitored. …”
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Susceptibility of Sardinella lemuru to emerging marine microplastic pollution by J.D.H. Palermo, K.L. Labrador, J.D. Follante, A.B. Agmata, M.J.R. Pante, R.N. Rollon, L.T. David

“…While results from Canonical Correspondence Analysis of ingested microplastic data had no relationship with the standard lengths of the sardine and the masses of ingested food materials at varying size classes, the total number of ingested microplastics from 2014 to 2016  were directly correlated (r²=0.91, <em>p</em>=0.003) with the human population at the landing sites  along the coastline of northern Mindanao.…”
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