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26481
Pandemic-Induced changes in Travel Behaviour: Insights of Pandemic’s Lasting impacts on Lahore’s Urban Mobility
Published 2025-01-01“… The COVID-19 epidemic, which began to spread globally in early 2020, created an abrupt change that has brought with it unimaginable challenges and profound adjustments to many elements and areas of human existence. This research delves into how the COVID-19 pandemic transformed travel patterns in Lahore, Pakistan. …”
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26482
An In Vitro Study of the Effects of Methotrexate Loaded Biocomposite Beads on MG63 Osteoblast Cells
Published 2025-01-01“…A cytotoxicity study of the methotrexate was performed by a human osteosarcoma (MG-63) cell line. Results indicated that the formation of a hydroxyapatite layer on the bead’s surface confirmed its biological activity. …”
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26483
Prevalence of gastrointestinal nematode parasites of dogs and associated risk factors in Gondar town, Northwest Ethiopia
Published 2025-01-01“…Intestinal parasites commonly infect dogs and can potentially spread to humans globally. Regrettably, numerous dog owners do not give priority to managing their pets' health, often ignoring treatment unless the animal is already ill. …”
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26484
Attitudes towards Donor Breast Milk in an Inner City Population
Published 2019-01-01“…Education on the benefits of mother’s own milk as well as donor breast milk and milk banks is an important public health initiative needed to increase acceptance of human milk as the optimal form of nutrition in infants.…”
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26485
Genomic changes during the evolution of the Coxiella genus along the parasitism-mutualism continuum
Published 2023-05-01“…Among them, Coxiella burnetii is a well-known pathogen causing Q fever in humans. This bacterium presents both intracellular (parasitic) and environmental (resistant) forms. …”
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26486
Effects of Hsa-miR-4741/LILRB2 on Senescence of Nucleus Pulposus Cells and Their Prognostic Values in Lumbar Disc Herniation
Published 2025-12-01“…Surgery is a common treatment strategy for LDH, but it can recur, resulting in recurrent disk herniation (RDH).Purpose To explore the predictive value of hsa-miR-4741 and LILRB2 in the prognosis of LDH surgery and the mechanism of nucleus pulposus senescence.Method The ROC curves of RDH based on hsa-miR-4741 and LILRB2 were constructed to evaluate their predictive values in the prognosis of LDH surgery. Human nucleus pulposus cells (NPC) was treated by TNF-α to construct a cell senescence model, studying the senescence mechanism. …”
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26487
Clothianidin and Thiacloprid Mixture Administration Induces Degenerative Damage in the Dentate Gyrus and Alteration in Short-Term Memory in Rats
Published 2021-01-01“…Chronic exposure to neonicotinoids in humans is related to autism, memory loss, and finger tremor. …”
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26488
Stability of Encapsulated Lactobacillus reuteri during Harsh Conditions, Storage Period, and Simulated In Vitro Conditions
Published 2021-01-01“…Viability of probiotics in the foods and human bodies is important, because a certain minimum count of bacteria is necessary to impose health promoting effects. …”
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26489
Chitosan’s Ability to Remove the Smear Layer—A Systematic Review of Ex Vivo Studies
Published 2025-01-01“…Ex vivo studies performed in non-endodontically treated extracted human permanent teeth with a fully formed apex, in which sodium hypochlorite was the main irrigant and chitosan was used as final irrigation to observe its capacity to remove the smear layer using a Scanning Electron Microscope (SEM), were included. …”
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26490
<i>AcOTApks</i> Gene-Based Molecular Tools to Improve Quantitative Detection of the Mycotoxigenic Fungus <i>Aspergillus carbonarius</i>
Published 2024-12-01“…Ochratoxin A (OTA) is a mycotoxin, a common contaminant of grapes and their derivatives, such as wine, and classified as possible human carcinogen (group 2B) by the International Agency for Research on Cancer (IARC). …”
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26491
miR-149 Alleviates Ox-LDL-Induced Endothelial Cell Injury by Promoting Autophagy through Akt/mTOR Pathway
Published 2021-01-01“…Here, we explored the protective effect and related mechanism of miR-149 in endothelial cells induced with oxidized low-density lipoprotein (ox-LDL). Methods. Human endothelial cell lines (HUVECs) were exposed to ox-LDL to induce endothelial injury. …”
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26492
Pharmacokinetic Evaluation of [C]CEP-32496 in Nude Mice Bearing BRAF Mutation-Induced Melanomas
Published 2018-09-01“…CEP-32496, also known as RXDX-105 or Agerafenib, is a new orally active inhibitor for the mutated v-raf murine sarcoma viral oncogene homolog B1 (BRAF V600E ), which has attracted considerable attention in clinical trials for the treatment of human cancers. Here, we used carbon-11-labeled CEP-32496 ([ 11 C]CEP-32496) as a positron emission tomography (PET) radiotracer to evaluate its pharmacokinetic properties and explore its potential for in vivo imaging. …”
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26493
11 Key Strategies in Using AI Chat GPT to Develop HOTS-Based Entrepreneurship Questionnaires
Published 2025-01-01“…This finding can be utilized by teachers as the latest generative model to increase the bank of diverse multiple-choice questions without replacing human expertise. …”
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26494
Modern approaches to the therapy of computer visual syndrome
Published 2018-07-01“…However, doctors noted the growth of pathological changes in the organs and systems of the human body, induced by work at the computer. It is computer syndrome, which includes changes in the skeleto-muscular system, carpal tunnel syndrome and computer vision syndrome (CVS). …”
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26495
Double-blind, randomised, placebo-controlled trial to evaluate the effectiveness of late gestation oral melatonin supplementation in reducing induction of labour rates in nulliparo...
Published 2025-01-01“…All data will be analysed by intention to treat.Ethics and dissemination The study is approved by the Western Australia Health Central Human Research Ethics Committee (RGS0000006283). …”
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26496
Evaluation of a PCR-based lateral flow device for detecting Aspergillus and Candida species from clinical specimens
Published 2025-02-01“…Results: The limits of detection of the multiplexed PCR were in the range of 5–100 CFU/mL for fungal spiked human blood samples. Against the clinical diagnosis of proven or probable IFDs, the findings show that the LFA system produced a high specificity of 99.4 % while the sensitivity was only moderate at 47.8 % due to the difficulty of extracting fungal DNA from blood samples. …”
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26497
The combination of rAAV pseudo-lipid nanoparticle and triamcinolone acetonide enables multi-administration to liver
Published 2025-03-01“…We showed successful but low efficient triple trafficking by LNP-rAAV2 carrying EGFP, human factor IX (hFIX), and luciferase (luc), due to its encapsulation characteristic. …”
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26498
Biotechnological bases of the development of cloned pig embryos
Published 2019-08-01“…Somatic cell nuclear transfer in pigs has a wide range of potential applications in various fields of human scientific and economic activities. However, the efficiency of producing cloned embryos in swine is still lower than that of other livestock species, in particular horses and cattle. …”
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26499
CircWDR78 inhibits the development of colorectal cancer by regulating the miR-653-3p/RGS4 axis
Published 2025-02-01“…Abstract Background Colorectal cancer (CRC) stands as one of the most serious threats to human health, with its mortality rate increase during the past years. …”
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26500
Factors Influencing Hospitalization Expenses Among Patients with Lung Cancer in China
Published 2025-01-01“…Lung cancer poses a serious threat to human health. The direct medical expense and indirect social economic burden caused by high morbidity and poor prognosis rate of malignant tumor are higher than other diseases around the world, especially in some developing countries such as China. …”
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