Heterogeneous focal adhesion cytoskeleton nanoarchitectures from microengineered interfacial curvature to oversee nuclear remodeling and mechanotransduction of mesenchymal stem cel... by Huayu Fan, Hui Zhao, Yan Hou, Danni Meng, Jizong Jiang, Eon-Bee Lee, Yinzheng Fu, Xiangdong Zhang, Rui Chen, Yongtao Wang

“…Methods Polydimethylsiloxane (PDMS)-based stencils were micropatterned to prepare the micropores for cell culture. The colonies of human mesenchymal stem cells (hMSCs) were formed by controlling cell seeding density to investigate the influences of cell density, curvature and heterogeneity on mechanotransduction. …”
Get full text

Microbiological Safety of Leafy Vegetables Produced at Houeyiho and Sèmè-Kpodji Vegetable Farms in Southern Benin: Risk Factors for Campylobacter spp. by Sylvain Daton Kougblénou, Alidéhou Jerrold Agbankpé, Justin Gbèssohélé Béhanzin, Tamègnon Victorien Dougnon, Alidah Victonie Aniambossou, Lamine Baba-Moussa, Honoré Sourou Bankolé

“…Foodborne infections, mainly those attributable to Campylobacter, are one of the most common causes of intestinal diseases, of bacterial origin in humans. Although the vehicle of transmission is not always identified, the most common vehicles are poultry, poultry products, and contaminated water. …”
Get full text

Encoding of cerebellar dentate neuron activity during visual attention in rhesus macaques by Nico A Flierman, Sue Ann Koay, Willem S van Hoogstraten, Tom JH Ruigrok, Pieter Roelfsema, Aleksandra Badura, Chris I De Zeeuw

“…To study cerebellar activity during visual attention we recorded extracellular activity of dentate nucleus (DN) neurons in two non-human primates (NHPs). NHPs were trained to read the direction indicated by a peripheral visual stimulus while maintaining fixation at the center, and report the direction of the cue by performing a saccadic eye movement into the same direction following a delay. …”
Get full text

Level of fecal neopterin and calprotectin in asymptomatic and symptomatic norovirus-infected children with malnutrition in Indonesia by Anisa Lailatul Fitria, Zayyin Dinana, Aussie Tahta Maharani, Alinda Syifa Fumizuki, Faiz Nabila Mumtazya, Dominikus Raditya Atmaka, Laura Navika Yamani, Juniastuti, Maria Inge Lusida, Soetjipto, Septa Indra Puspikawati

“…We assessed the fecal neopterin and calprotectin from the stools samples collected during viral diarrhea surveillance in Surabaya, East Java, Indonesia, using commercially ELISA kit from BT Lab (Zhejiang, China) for human neopterin and calprotectin. The statistical differences were tested using Kruskal-Wallis nonparametric test. …”
Get full text

An assessment of breast cancer HER2, ER, and PR expressions based on mammography using deep learning with convolutional neural networks by Shun Zeng, Hongyu Chen, Rui Jing, Wenzhuo Yang, Ligong He, Tianle Zou, Peng Liu, Bo Liang, Dan Shi, Wenhao Wu, Qiusheng Lin, Zhenyu Ma, Jinhui Zha, Yonghao Zhong, Xianbin Zhang, Guangrui Shao, Peng Gong

“…Abstract Mammography is the recommended imaging modality for breast cancer screening. Expressions of human epidermal growth factor receptor 2 (HER2), estrogen receptor (ER), and progesterone receptor (PR) are critical to the development of therapeutic strategies for breast cancer. …”
Get full text

Damage symptoms, development, and reproductive performance of the fall armyworm, Spodoptera frugiperda (J.E. Smith) (Lepidoptera: Noctuidae) on fodder maize and cob by Hend O. Mohamed, Hassan F. Dahi, Azza A. Awad, Walaa E. Gamil, Bassam F. Fahmy

“…The results exhibited that the FAW larvae were able to feed on and infest both fodder maize and corn cobs, causing significant damage particularly to the cobs making them unsuitable for marketing and human consumption. Moreover, the larvae and pupae from the corn cobs had the greatest weight and were significantly affected by food items. …”
Get full text

Phase 1 study of safety, tolerability, and efficacy of intradermal DNA vaccine ASP2390 in adults allergic to house dust mites by Thomas Kayser, MD, BS, Ronald Smulders, MD, PhD, Tomohiro Kusawake, PhD, Erik Wambre, PhD, Gurunadh R. Chichili, PhD, Mary B. Blauwet, DrPH, Anna Spence, MS, Melanie Patton, BS, Rima Tabash, PhD, Hannah A. DeBerg, PhD, Sugandhika Khosa, MS, Philipp Badorrek, MD, Jens M. Hohlfeld, MD, Brian C. Ferslew, PharmD, PhD

“…Objective: We evaluated the safety, tolerability, and efficacy of first-in-human intradermal ASP2390 in adults with HDM allergy. …”
Get full text

Electricity Theft Detection Using Machine Learning in Traditional Meter Postpaid Residential Customers: A Case Study on State Electricity Company (PLN) Indonesia by Alief Pascal Taruna, Galih Arisona, Dwi Irwanto, Arif Bijak Bestari, Wildan Juniawan

“…These findings demonstrate the model’s effectiveness in delivering reliable TO recommendations, supporting PLN’s operational strategies, and offering practical benefits through a more objective, standardized TO process that minimizes human error and improves efficiency.…”
Get full text

Assessing Knowledge, Attitudes, and Practices of Healthcare Workers regarding Biomedical Waste Management at Biyem-Assi District Hospital, Yaounde: A Cross-Sectional Analytical Stu... by Sylvain Honoré Woromogo, Gwladys Guetsé Djeukang, Félicité Emma Yagata Moussa, Jesse Saint Saba Antaon, Kingsley Ngah Kort, Pierre Marie Tebeu

“…Healthcare workers are responsible for the proper management of this waste for human safety and for the protection of the environment. …”
Get full text

ANGPTL4 Attenuates Ang II-Induced Atrial Fibrillation and Fibrosis in Mice via PPAR Pathway by Xi Zhu, Xiaogang Zhang, Xinpeng Cong, Luoning Zhu, Zhongping Ning

“…Mice were infused with Ang II (2000 ng/kg/min) and were administrated with recombinant human ANGPTL4 (rhANGPTL4, 20 μg/kg/day) for 3 weeks. …”
Get full text

Health literacy and influencing factors in university students across diverse educational fields in Kazakhstan by Zhaniya Dauletkaliyeva, Zhanerke Bolatova, Nurbek Yerdessov, Karina Nukeshtayeva, Olzhas Zhamantayev, Aliya Takuadina, Gaukhar Kayupova

“…The highest HL score was in students of Health Sciences field (88.22 ± 17.53), whereas mean HL score in students of Engineering field of study was 83.27 ± 20.07, and it was 86.13 ± 18.11 for the Humanities and Social sciences field of study. The factors negatively associated with HL were region of origin, health information searching, lack of basic life support skills, smoking, self-assessment of health as bad, and missing study days. …”
Get full text

Chronic NaAsO2 exposure promotes migration and invasion of prostate cancer cells by Akt/GSK-3β/β-catenin/TCF4 axis-mediated epithelial-mesenchymal transition by Zhi-Hui Zhang, Hai-Xin Yan, Ming-Dong Liu, Feng-Wen Niu, Kai Yao, Shi-Yao Feng, Xi Li, Yuan-Hua Chen, Dong-Dong Xie

“…Inorganic arsenic is a Class I human Carcinogen. However, the role of chronic inorganic arsenic exposure on prostate cancer metastasis still unclear. …”
Get full text

Mechanistic insights into 125I seed implantation therapy for Cholangiocarcinoma: focus on ROS-Mediated apoptosis and the role of GPX2 by Jun Luo, Zheng Yao, Weiren Liang, Danjun Song, Hui Zeng, Yi Jiang, Zhehan Bao, Jiaping Zheng, Yinan Ding

“…Materials and methods Human cholangiocarcinoma cell lines QBC939 and RBE were purchased for in vitro studies. …”
Get full text

Rh and Kell phenotyping in voluntary blood donors: A study from a tertiary care blood center of western India by Sangita D. Shah, Nidhi M. Bhatnagar, Mamta C. Shah, Garima H. Thakkar, Ujjwal Ahuja, Anu Patel, Drashti Gajera, Priya G. Kalavadiya

“…INTRODUCTION: In human beings, there are 45 blood group systems and 360 antigens currently recognized by ISBT (July 2023). …”
Get full text

Signal Processing-Free Intelligent Model for Power Quality Disturbances Identification by Mohammed F. Al-Mashdali, Asif Islam, Abdulbasit Hassan, Md Shafiullah, Mujahed Al-Dhaifallah, Khalid Al Fuwail

“…By directly examining PQD images generated from signal data, these models reduce the requirement for human-crafted features. The study analyzes alternative CNN setups, training datasets, and disturbance types to measure model performance. …”
Get full text

RAB3GAP2 dysregulation in adult T-cell leukemia/lymphoma (ATLL) compared to acute lymphoblastic leukemia (ALL): a molecular perspective by Samira Pourrezaei, Arash Letafati, Ghazale Molaverdi, Mehdi Norouzi, Sayed-Hamidreza Mozhgani

“…Abstract Adult T-cell leukemia/lymphoma (ATLL) is a type of blood cancer related to human T-cell lymphotropic virus type 1 (HTLV-1). …”
Get full text

The impact of glucocorticoid receptor transactivation on context-dependent cell migration dynamics by Szonja Polett Pósa, Éva Saskői, Lili Bársony, Lőrinc Pongor, Fanni Fekete, János Papp, Anikó Bozsik, Attila Patócs, Henriett Butz

“…Based on data from 1085 human breast cancer specimens, GR pathway expression correlated with migratory, extracellular matrix, and angiogenesis gene signatures. …”
Get full text

Photothermal performance of nanofluids: An experimental study on direct absorption solar energy conversion using graphene oxide and its binary composites for water purification by Abdul Sattar, Bai Bofeng, M. Adeel Munir, Muhammad Farooq, S. Bilal, M. Imran Khan, Noreen Sher Akbar, Mohammed Ilyas Khan, Mohammad Rehan, Fahid Riaz

“…Water scarcity affects two-thirds of the world’s population and is one of the most important challenges to human development. Nanotechnology led by solar evaporation is emerging to solve water resource problems by absorbing solar energy to vaporize nanofluid samples, especially in areas where seawater resources are abundant and economical. …”
Get full text

Assessment of Nitrogen Ceilings for Dutch Agricultural Soils to Avoid Adverse Environmental Impacts by Wim de Vries, Hans Kros, Oene Oenema, Jan Willem Erisman

“…This leads to a series of environmental impacts, including: (1) nitrate (NO3) contamination of drinking water, (2) eutrophication of freshwater lakes, (3) acidification and biodiversity impacts on terrestrial ecosystems, (4) ozone and particle formation affecting human health, and (5) global climate change induced by emissions of N2O. …”
Get full text

Study on Change of Landscape Pattern Characteristics of Comprehensive Land Improvement Based on Optimal Spatial Scale by Baoping Feng, Hui Yang, Yarong Ren, Shanshan Zheng, Genxiang Feng, Yuwei Huang

“…This scale can reflect the spatial variability of the landscape pattern in the study area and is the most suitable analysis range. (3) The fragmentation degree of paddy fields as landscape matrix decreased and the landscape dominance degree increased in the comprehensive land improvement; the degree of fragmentation of irrigated land and agricultural land for facilities increased, the aggregation of land for construction increased, the dominance degree of the pond surface decreased, and the overall landscape diversity of each mosaic decreased; the landscape heterogeneity of ditches, rural roads, forest and grassland corridors was weakened, and the ecosystem service function was weakened. (4) The trend of increased fragmentation, simplification of landscape types, and decreased diversity presented by the landscape pattern clearly indicates that the landscape pattern of the study area has been seriously damaged to some extent under the influence of human activities. This damage not only has a direct negative impact on the local ecological environment, but also poses a potential threat to the sustainable development of the region.…”
Get full text