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23541
Critical signals for grassland desertification prediction in the transition zone between desert and typical steppe in InnerMongolia, China
Published 2025-01-01“…Global climate change and intensifying human activities have driven an accelerated desertification of grasslands in arid and semi-arid regions. …”
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23542
Pollution Characteristics and Source Analysis of Carbonaceous Components in PM2.5 in a Typical Industrial City
Published 2024-03-01“…Abstract Carbonaceous components are important components of fine atmospheric particulate matter (PM2.5) and can affect the local environment, climate, and human health. In this study, online observation data from September 1, 2022, to August 31, 2023, were used to analyze the carbonaceous components, namely, organic carbon (OC) and elemental carbon (EC), in PM2.5 in Jincheng, which is a typical industrial city. …”
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23543
Development of Virus-Like Particles (VLPs) for Hepatitis C Virus genotype 4: a novel approach for vaccine development in Egypt
Published 2025-01-01“…Methods Lentiviral-based vectors were constructed and employed to integrate the full-length sequence of Core, E1, E2, and P7 genes of HCV genotype 4 into the genome of Human Embryonic Kidney cells (HEK293T). Upon the expression, HCV structural proteins can oligomerize and self-assemble into VLPs mimicking the structure of HCV native virus. …”
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23544
Research on the possibility of carrying out convoy driving missions using vehicles with varying degrees of autonomy
Published 2024-12-01“… The objective of this work is to assess the possibility of driving unmanned vehicles in a convoy, depending on the vehicle type (wheeled or tracked, level 0, according to SAE J3016), and the mutual coincidence with a human-controlled vehicle in accordance with the driving scenario adopted. …”
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23545
Current developments in robotic assistance technology for total knee arthroplasty: a comprehensive overview
Published 2025-01-01“…Total knee arthroplasty, also known as TKA, is one of the most effective treatments for osteoarthritis of the knee that has progressed to the end stage. The inevitable human factor in conventional total knee arthroplasty (TKA) frequently results in poor positioning of the prosthesis during the reconstruction of the lower limb's biomechanical axis. …”
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23546
Novel insights into immunopathogenesis and crucial biomarkers between primary open‐angle glaucoma and systemic lupus erythematosus
Published 2024-12-01“…Finally, reverse transcription quantitative real‐time polymerase chain reaction (RT‐qPCR) was performed in human trabecular meshwork stem cells to validate the five identified biomarkers. …”
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23547
Correlation between MDA Level and Chitotriosidase-1 Activity in Seminal Fluid of Iraqi Infertile Males
Published 2024-12-01“…The notable chitinase in humans plays a significant role in the body's immunological response and is linked to inflammation, infection, tissue damage, and remodeling processes. …”
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23548
<i>Ex Vivo</i> Regional Gene Therapy Compared to Recombinant BMP-2 for the Treatment of Critical-Size Bone Defects: An In Vivo Single-Cell RNA-Sequencing Study
Published 2025-01-01“…Compared to recombinant human BMP-2 (rhBMP-2), which is approved for clinical use, regional gene therapy may have unique benefits related to the addition of MSCs and the sustained release of BMP-2. …”
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23549
The Importance of Platelet-Derived Growth Factors as Markers of Survival and Severity of COVID-19 in Patients Undergoing Monthly Follow-Up
Published 2024-01-01“…Platelets are the first to reach the site of tissue damage and secrete substances like platelet growth factors (GFs), which perform many different functions in the human body. Many studies suggest that GFs such as transforming GF (TGF), platelet-derived GF (PDGF), or insulin-like GF-1 (IGF-1) may be markers of survival, disease severity, and post-coronavirus disease (COVID) complications. …”
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23550
A Systematic Review and Meta-analysis of Single-group Studies Assessing the Role of Calcium Hydroxylapatite in Aesthetic Enhancements and Satisfaction
Published 2024-12-01“…Single-group studies with at least 10 human adults were included. Summary measures of patients satisfaction and global aesthetic improvement scores were combined using the generalized linear mixed model. …”
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23551
The Australian and New Zealand Fontan Registry Quality of Life Study: Protocol for a population-based assessment of quality of life among people with a Fontan circulation, their pa...
Published 2022-09-01“…Descriptive analyses and multilevel models will be used to examine QOL across groups and to investigate potential explanatory variables.Ethics and Dissemination Approval has been obtained from all relevant Human Research Ethics Committees (HRECs), including the Sydney Children’s Hospitals Network and the Royal Children’s Hospital Melbourne HRECs. …”
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23552
Genetic determinants of COVID-19 severity and mortality: ACE1 Alu 287 bp polymorphism and ACE1, ACE2, TMPRSS2 expression in hospitalized patients
Published 2025-01-01“…Background The angiotensin-converting enzyme 2 (ACE2) and the transmembrane serine protease 2 (TMPRSS2) are central human molecules in the SARS-CoV-2 virus-host interaction. …”
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23553
Performance of HPV16/18 in Triage of Cytological Atypical Squamous Cells of Undetermined Significance
Published 2019-01-01“…Context. Human papillomavirus (HPV) testing is widely used in cervical cancer screening in women; however, its efficiency in triaging women with atypical squamous cells of undetermined significance (ASC-US) needs to be validated. …”
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23554
The record-breaking precipitation event of December 2022 in Portugal
Published 2025-02-01“…<p>Extreme precipitation events (EPEs) potentially present an enormous societal risk and often lead to major human and economic impacts. In the mid-latitudes, such EPEs are often triggered by intense extratropical cyclones and their associated frontal systems. …”
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23555
Modeling optimal combination of breast and cervical cancer screening strategies in China
Published 2025-02-01“…Results The optimal combination strategy was biennial breast ultrasonography (BUS) and mammography (MAM) in parallel screening and quinquennial human papillomavirus (HPV) for breast and cervical cancer screening under the threshold of the annual per capita social cost investment (PCSCI) (18.80 USD) in China. …”
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23556
Operativity of the Taunsa Barrage, Pakistan: Experimental Investigation on the Subsidiary Weir
Published 2024-12-01“…River barrages ensure water availability for enhanced irrigation and human consumption. Of course, effective and sustainable management of existing barrages requires controlling riverbed erosion through appropriately designed stilling basins with their appurtenances. …”
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23557
CircSPG21 ameliorates oxidative stress-induced senescence in nucleus pulposus-derived mesenchymal stem cells and mitigates intervertebral disc degeneration through the miR-217/SIRT...
Published 2025-02-01“…Results CircSPG21 expression was significantly decreased in both human and rat IVDD tissues, whereas miR-217 was upregulated and SIRT1 was downregulated. …”
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23558
Basal Cell Carcinoma Diagnosed by Dermoscopy in Dermatology Clinic of the Miguel Enríquez University Hospital
Published 2023-08-01“…<strong>Foundation:</strong> basal cell carcinoma is a very common malignant tumor in humans. It is considered locally invasive, also aggressive and destructive. …”
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23559
Bioactive phytochemical compounds characterization, anti-oxidant and anti-microbial activity of the methanol and acetonitrile leaf extracts of Pithecellobium dulce
Published 2025-05-01“…Therefore, P. dulce leaf extracts may play a significant role in inhibiting human infections.…”
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23560
In Vitro Antibacterial, Antioxidant, Cytotoxicity Activity, and In Silico Molecular Modelling of Compounds Isolated from Roots of Hydnora johannis
Published 2024-01-01“…The cytotoxicity of extracts from roots of H. johannis was conducted against MCF-7 cell lines (human breast cancer) by MTT assay. According to the cytotoxicity study, n-hexane extract exhibited a high level of toxicity with 28.9 ± 5.6% cell viability. …”
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