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23421
A novel machine learning methodology for the systematic extraction of chronic kidney disease comorbidities from abstracts
Published 2025-02-01“…Abstracts about a disease affecting CKD development and/or progression were selected by multiple ML classifiers trained on a human-labelled sample. The best classifier was further trained with active learning. …”
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23422
Resident action in smart waste management during landfill disclosure transition: Insights from Yogyakarta's smart city initiatives
Published 2025-06-01“…Key elements of the methodological framework include sensing, learning, understanding, and acting, enabling a comprehensive exploration of the technological and human dimensions of waste management. Advanced predictive models analyze patterns in waste generation, optimizing system responsiveness and efficiency, while qualitative data reveal the critical role of education and tailored communication strategies in fostering resident participation. …”
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23423
Nutritional Properties, Antioxidant and Antihaemolytic Activities of the Dry Fruiting Bodies of Wild Edible Mushrooms Consumed by Ethnic Communities of Northeast India
Published 2021-12-01“…This study established the nutritional and health-promoting benefits of wild edible mushrooms of Northeast India region for consumption as functional foods in the human diet.…”
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23424
Newly identified single-nucleotide polymorphism associated with the transition from nonalcoholic fatty liver disease to liver fibrosis: results from a nested case-control study in...
Published 2025-12-01“…For our in vitro investigations, we employed the LX-2 human hepatic stellate cell line. Our procedures included cultivating these cells, employing SAMM50-rs2073080 plasmid techniques to enhance the expression of recently discovered SNPs, and conducting biochemical assays. …”
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23425
Caries affected Dentin biomodification using Bromelain, Riboflavin photosensitizer via UVA, and Chitosan Nanoparticles on shear bond strength and microleakage scores: A SEM evaluat...
Published 2025-02-01“…Materials and methods: Sixty-four human molars in which carious lesions extend till the middle third of the dentin were included. …”
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23426
Celastrol boosts fluconazole efficacy against vaginal candidiasis: in vitro and in vivo evidence
Published 2025-01-01“…A negligible hemolytic effect of celastrol against human erythrocytes was observed. In the in vivo model of VVC, the combination of FLZ and celastrol in vaginal gel revealed a drastic reduction in the fungal burden with apparently normal vaginal tissue. …”
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23427
Forecasting CO2 emissions in the Persian Gulf States
Published 2017-12-01“…CO2 accounts for 58.8 percent of all greenhouse gases released via human activities, consequently, presenting a malign impact on the environment through climate change, global warming, biodiversity, acid rain and desertification among others. …”
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23428
ONLINE PROJECTS AS A FORM OF SPREADING PEDAGOGICAL BIOGRAPHICAL KNOWLEDGE IN THE CONTEXT OF OPEN SCIENCE
Published 2023-10-01“…The article reveals thetrend of an increase in the number of biographical online projects in the Ukrainian segment of the Facebook social network during 2020–2022, caused by the decolonization of the Ukrainian humanities. 4 proven models for implementing biographical online projects have been proposed for a widespread use: "Online project on Facebook", "Online project on Facebook and Instagram", Online project on Facebook using a web portal/website", Online project on Facebook as a source ofvirtual exhibition on the website". …”
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23429
Wait Times for Gastroenterology Consultation in Canada: The Patients’ Perspective
Published 2010-01-01“…As part of the Canadian Association of Gastroenterology’s Human Resource initiative, a questionnaire was developed to survey patients regarding wait times for initial gastroenterology consultation and its impact. …”
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23430
Favorable Nonclinical Safety Profile of RSVpreF Bivalent Vaccine in Rats and Rabbits
Published 2024-12-01“…RSVpreF bivalent vaccine, with or without Al(OH)<sub>3</sub>, was administered intramuscularly (IM) at 2× the human dose to animals in both studies. <b>Results</b>: Locally tolerated, reversible, inflammatory responses at the injection sites and the draining lymph nodes were observed as typical findings following vaccination. …”
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23431
MicroRNA-28-5p Regulates Liver Cancer Stem Cell Expansion via IGF-1 Pathway
Published 2019-01-01“…The correlation between miR-28-5p and IGF-1 was confirmed in human HCC tissues. Furthermore, the miR-28-5p knockdown HCC cells were more sensitive to sorafenib treatment. …”
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23432
Coupled CRC 2D and ALI 3D Cultures Express Receptors of Emerging Viruses and Are More Suitable for the Study of Viral Infections Compared to Conventional Cell Lines
Published 2020-01-01“…Infections of emerging and reemerging viruses (SARS-CoVs, influenza H1N1, etc.) largely and globally affect human health. Animal models often fail to reflect a physiological status because of species tropism of virus infection. …”
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23433
Beta oscillations predict the envelope sharpness in a rhythmic beat sequence
Published 2025-01-01“…Most environmental rhythms and patterns in human behavior, such as walking, dancing, and speech do not, however, display strict isochrony but are instead quasi-periodic. …”
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23434
A perspective on the current state of smartphone-based mobile applications for scar assessment
Published 2025-01-01“…Nine devices were tested on human skin, and only two on scarred skin. Seven tools were evaluated for both validity and reliability, while four were only tested for validity. …”
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23435
Association between ethylene oxide exposure and cognitive function in older adults from NHANES data
Published 2025-01-01“…Abstract Ethylene Oxide (EO), a volatile organic compound, has garnered considerable attention for its potential impact on human health. Yet, the ramifications of EO exposure on the cognitive functionality of the elderly remain unclear. …”
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23436
Viral Transcript and Tumor Immune Microenvironment-Based Transcriptomic Profiling of HPV-Associated Head and Neck Squamous Cell Carcinoma Identifies Subtypes Associated with Progno...
Published 2024-12-01“…Human papillomavirus (HPV)-associated head and neck squamous cell carcinoma (HPV-positive HNSCC) has distinct biological characteristics from HPV-negative HNSCC. …”
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23437
Hydrogels of Poly(2-hydroxyethyl methacrylate) and Poly(N,N-dimethylacrylamide) Interpenetrating Polymer Networks as Dermal Delivery Systems for Dexamethasone
Published 2025-01-01“…<b>Conclusions</b>: The study reveals that the IPNs of PHEMA and PDMAM appear to be suitable platforms for dermal delivery of dexamethasone as they have appropriate mechanical properties, providing tools to control drug loading and release, and they are biocompatible with human skin cells.…”
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23438
dyphAI dynamic pharmacophore modeling with AI: a tool for efficient screening of new acetylcholinesterase inhibitors
Published 2025-02-01“…To further validate the predictions, nine molecules were acquired and tested for their inhibitory activity against human AChE. Experimental results revealed that molecules, 4 (P-1894047), with its complex multi-ring structure and numerous hydrogen bond acceptors, and 7 (P-2652815), characterized by a flexible, polar framework with ten hydrogen bond donors and acceptors, exhibited IC₅₀ values lower than or equal to that of the control (galantamine), indicating potent inhibitory activity. …”
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23439
Impact of primary care benefits on healthcare utilisation and estimated out-of-pocket expenses in urban, rural and remote settings in the Philippines
Published 2025-01-01“…Background This study aimed to determine the effects of primary care interventions on healthcare utilisation and estimated out-of-pocket (OOP) expenses in selected urban, rural and remote settings in the Philippines.Methodology Context-specific measures relating to expanding healthcare provider networks, augmenting the health human workforce and subsidising transportation costs were implemented to strengthen primary care systems. …”
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23440
Effect of Skin Protectants on the Total Inward Leakage of N95 Respirators: Testing with an Advanced Static Headform
Published 2022-05-01“…Recent pilot studies involving human subjects have examined the effect of skin protectants on the performance of respirators/masks through fit testing, but their findings are heavily impacted by between-subject variability. …”
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