Realist evaluation of the impact of the research translation process on health system sustainability: a study protocol by Yvonne Zurynski, Delia Hendrie, Suzanne Robinson, Elizabeth Geelhoed, Abby Mosedale

“…This approach to evaluation of a research translation funding programme may be adapted to similar programmes operating in other settings.Ethics and dissemination Curtin University Human Research Ethics Committee, Western Australia, approved this study (approval number: HRE2020-0464). …”
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Construction and Investigation of MicroRNA-mRNA Regulatory Network of Gastric Cancer with Helicobacter pylori Infection by Ping Yang, Junjie Liu, Tianci Yang, Lei Zhang, Peiyou Gong, Boqing Li, Xiuzhi Zhou

“…Helicobacter pylori (H. pylori) is a common human pathogen, which is closely correlated with gastric cancer (GC). …”
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Identifying the function of novel cross-species microRNAs from the excretory-secretory products of Angiostrongylus cantonensis fifth-stage larvae by Kuang-Yao Chen, Yi-Hsuan Lin, Chien-Ju Cheng, Yi-Hao Huang, Sheng-Yu Lin, Chyi-Liang Chen, Cheng-Hsun Chiu

“…Background: Angiostrongylus cantonensis is a significant foodborne zoonotic parasite that causes severe neuropathological damage and symptoms in humans. Excretory-secretory products (ESPs) play a pivotal role in elucidating host-parasite interactions and can aid in penetrating host defensive barriers in helminths. …”
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Analysis of differentially expressed genes in hypertension and hypertensive cerebral hemorrhage via RNA-sequencing by Hongwu Qi, Min Qiao, Yansong Liu, Weijun Zeng, Lizhao Zhang, Hongjun Guo

“…The RT-qPCR validation results in human subjects and cell models were generally consistent with the sequencing results. …”
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Research on power plant security issues monitoring and fault detection using attention based LSTM model by Shengda Wang, Zeng Dou, Danni Liu, Han Xu, Ji Du

“…Wind power is well distributed around the world, making it suitable to be exploited in human activities for the general welfare of society. …”
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Effects of fiber engraving laser on metallurgical, surface topography, and corrosion properties of AZ80 magnesium-based alloy by Narges Ahmadi, Homam Naffakh-Moosavy, Seyed Mohammad Mahdi Hadavi, Fatemeh Bagheri

“…Magnesium, a lightweight metal similar to natural bone, shows no toxicity and can aid in hard tissue recovery when implanted in the human body. However, its main drawback is its fast degradation rate in medical applications. …”
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Study protocol: an observational study of distress, immune function and persistent pain in HIV by John A Joska, Mark R Hutchinson, Maia Lesosky, Victoria J Madden, Ncumisa Msolo, Luyanduthando Mqadi, Gillian J Bedwell, Jonathan Grant Peter, Romy Parker, Andrew Schrepf, Robert R Edwards

“…The study has been approved by the Human Research Ethics Committee of the University of Cape Town (approval number: 764/2019) and the City of Cape Town (ref: 24699).Trial registration number NCT04757987.…”
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Exploring the causal paths and longitudinal impact of telework on health: the TeleHealth survey–data linkage study protocol by Barbara Cagnie, Bas de Geus, Robby De Pauw, Eduardo Antonio Bracho Montes de Oca, Laura Int Panis, Mathieu Verbrugghe, Els De Waegeneer

“…To mitigate biases associated with non-probabilistic samples and attrition, standardised probability weights scoring will be derived from the data.Ethics and dissemination This study involves human participants and has been approved by the Ethics Committee of Universitair Ziekenhuis Gent (Nr°. …”
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Economic Spectrofluorometric Bioanalysis of Empagliflozin in Rats’ Plasma by Bassam Ayoub, Noha El Zahar, Haidy Michel, Mariam Tadros

“…Moreover, with the suitable modifications, the described novel extraction of empagliflozin could be adopted to human plasma samples and future clinical studies. …”
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Probe – Integrated electrochemical sensing platform for detection of trace levels of Dapoxetine hydrochloride drug residue in water and drug formulations by H. Alwael, N.A. Asiri, B.G. Alhogbi, A.S. Alharthi, E.A. Bahaidarah, T.N. Abduljabbar, D.F. Baamer, M. Madkour, F.A. Zainy, M.S. El-Shahawi

“…The extensive use and misuse of selective serotonin reuptake inhibitors (SSRIs) in drug formulations has resulted in their accumulation in food sources and environment, posing noteworthy threats to human health and the global economy. Dapoxetine hydrochloride (DPH) is one of the recent oral drugs frequently misused for the treatment of male sexual dysfunction of premature ejaculation and has lately international attention. …”
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Metal-free production of natural blue colorants through anthocyanin–protein interactions by Wenxin Wang, Peiqing Yang, Fuqing Gao, Yongtao Wang, Zhenzhen Xu, Xiaojun Liao

“…Objectives: Our study aims to introduce a metal-free approach to achieve blue coloration in commonly distributed non-acylated 3-glucoside ACNs by exploring their interactions with proteins and unveiling the underlying mechanisms. Methods: Using human serum albumin (HSA) as a model protein, we investigated the structural influences of ACNs on their blue color generation using visible absorption spectroscopy, fluorescence quenching, and molecular simulations. …”
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Jidoka-DT simulator programmed by hybridize XGboost-LSTM to evaluate helmets quality produced by Rice-Straw-alumina plastic dough to resist shocks and impenetrable by Ahmed M. Abed, Ahmed Fathy, Radwa A. El Behairy, Tamer S Gaafar

“…The dough has been tested via a Digital Twin (DT) simulator that relies on human dexterity in mapping the helmet surface as a finite element (FEM) that is called Jidoka-DT. …”
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Prognostic implications of immune classification based on PD-L1 expression and tumor-infiltrating lymphocytes in endocervical adenocarcinoma by Li-Jun Wei, Zi-Yun Wu, Li-Yan Wu, Ying-Wen Wu, Hao-Yu Liang, Rong-Zhen Luo, Li-Li Liu

“…ECA can be histologically classified into human papillomavirus-associated (HPVA) and non-HPVA (NHPVA) types. …”
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Hybrid peptides inspired by the RWQWRWQWR sequence inhibit cervical cancer cells growth in vitro by Natalia Ardila-Chantré, Claudia Marcela Parra-Giraldo, Yerly Vargas-Casanova, Andrea Carolina Barragán-Cardenas, Ricardo Fierro-Medina, Zuly Jenny Rivera-Monroy, Jhon Erick Rivera-Monroy, Javier Eduardo García-Castañeda

“…In vitro cytotoxicity of hybrid peptides in human cervical cancer cells lines HeLa and Ca Ski was determined by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay. …”
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Cs+ Adsorption and Pyrolytic Volume Reduction Performance of KR-01 Mixed Ion Exchange Resin by Weilei GUO, Hongyi GAO, Jinchi MAO, Renliang YUE, Haidi LIU

“…Cesium-137 (137Cs) is one of the most common radioactive substances in nuclear reactor wastewater, developing efficient Cs+ adsorbing materials is of paramount importance for sustainable development of nuclear energy, human health protection, and environmental conservation. …”
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Umbilical Cord Mesenchymal Stem Cell-Derived Small Extracellular Vesicles Deliver miR-21 to Promote Corneal Epithelial Wound Healing through PTEN/PI3K/Akt Pathway by Xiaolong Liu, Xuran Li, Guangyuan Wu, Pengfei Qi, Yanyan Zhang, Zhiyu Liu, Xinyue Li, Yu Yu, Xiangmei Ye, Yang Li, Dongguang Yang, Yueqiu Teng, Ce Shi, Xin Jin, Sen Qi, Yuting Liu, Shudan Wang, Ying Liu, Fenglin Cao, Qingran Kong, Zhenkun Wang, Hong Zhang

“…This study investigated the mechanism of human umbilical cord MSC-derived small extracellular vesicles (HUMSC-sEVs) on corneal epithelial wound healing. …”
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Bone Marrow Stromal Cells Generate a Pro-Healing Inflammasome When Cultured on Titanium–Aluminum–Vanadium Surfaces with Microscale/Nanoscale Structural Features by David J. Cohen, Christine M. Van Duyn, Jingyao Deng, Musaddiq K. Lodi, Michelle B. Gallagher, James T. Sugar, Jeremy J. Rawlinson, Preetam Ghosh, Barbara D. Boyan, Zvi Schwartz

“…The surface topography and chemistry of titanium–aluminum–vanadium (Ti6Al4V) implants play critical roles in the osteoblast differentiation of human bone marrow stromal cells (MSCs) and the creation of an osteogenic microenvironment. …”
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Generation and characterization of two induced pluripotent stem cell lines (ICGi052-A and ICGi052-B) from a patient with frontotemporal dementia with parkinsonism-17 associated wit... by E. V. Grigor’eva, A. A. Malakhova, E. S. Yarkova, J. M. Minina, Y. V. Vyatkin, J. A. Nadtochy, E. A. Khabarova, J. A. Rzaev, S. P. Medvedev, S. M. Zakian

“…The iPSC lines ICGi052-A and ICGi052-B proliferate stably, form colonies with a morphology characteristic of human pluripotent cells, have a normal diploid karyotype (46,XX), express endogenous alkaline phosphatase and pluripotency markers (OCT4, NANOG, SSEA-4 and TRA-1-60) and are able to differentiate into derivatives of three germ layers: ento-, ecto- and mesoderm. …”
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Antimicrobial Resistance Profile of E. coli Isolated from Raw Cow Milk and Fresh Fruit Juice in Mekelle, Tigray, Ethiopia by Haftay Abraha Tadesse, Netsenet Berhe Gidey, Kidane Workelule, Hagos Hailu, Seyfe Gidey, Abrha Bsrat, Habtamu Taddele

“…They cause great suffering and are transmitted directly or indirectly between animals and humans and circulate in the global environment. E. coli are among them, causing a major public health problem. …”
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KLF5 silencing restrains proliferation, invasion, migration and angiogenesis of gallbladder carcinoma cells by transcriptional regulation of PDGFA by Xiaowei Lu, Kui Hu, Dandan Zhang, Xuefeng Yin, Jifeng Nie, Kai Zhao

“…Conclusion Collectively, our results suggest that KLF5 regulates GBC cell proliferation, invasion, migration, angiogenesis, as well as apoptosis, via mediating PDGFA transcriptionally, which might provide a novel therapeutic strategy for treatment of human GBC.…”
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