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22921
The PTP1B Inhibitor Trodusquemine (MSI-1436) Improves Glucose Uptake in Equine Metabolic Syndrome Affected Liver through Anti-Inflammatory and Antifibrotic Activity
Published 2023-01-01“…Taken together, the presented data suggest that the PTP1B inhibition strategy and the use of its specific inhibitor MSI-1436 represents a promising option for the improvement of liver tissue integrity and homeostasis in the course of EMS and adds more insights for ongoing clinical trials for human MetS management.…”
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22922
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22923
A new perspective on cardiovascular function and dysfunction during endurance exercise: identifying the primary cause of cardiovascular risk
Published 2024-04-01“…Therefore, the rise in core temperature during endurance exercise in humans is proportional to generated work. Cutaneous vasodilation occurs when the core temperature threshold is reached. …”
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22924
Evaluation of the Transition-to-Practice Arrangements for Novice Perioperative Nurses: Protocol for a Mixed Methods Study
Published 2025-01-01“…ResultsThis project received approval in June 2023. Following this, Human Research Ethics Committee approval was sought for phases 1 and 2, and recruitment began. …”
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22925
The EU Sanctions Policy: A Thorny Path of Transformation
Published 2025-02-01“…It shows that it was as early as the 2010s that the EU countries started to switch from using sanctions primarily as a means of conveying an addressee a certain ‘political message’ designed to ensure human rights and democratic values, to harnessing them as an economic leverage. …”
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22926
Р. DESCARTES: PRINCIPLES OF RATIONALISTIC METHOD AND MORALITY (TO THE QUESTION ON THE METHODS OF SCIENTIFIC RESEARCH IN THE FIELD OF PHILOSOPHY AND SOCIAL WORK)
Published 2024-12-01“…The achievement of this goal will contribute to the formation of critical thinking in novice scientists, which, based on doubt, should ultimately be directed not at denial and removal, which is irrational destruction, but at achieving and comprehending the truth, which should be the basis for finding constructive solutions in such meaningful areas of human activity as philosophy and practical social work. …”
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22927
Interacting Large Language Model Agents Bayesian Social Learning Based Interpretable Models
Published 2025-01-01“…Traditionally, such models are used in economics to study interacting human decision-makers.…”
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22928
Information War in Syria
Published 2015-02-01“…Analyzing numerous publications, photos and videos, largely specially rigged to achieve the desired result, it is difficult to say about the objective picture of what is happening, but it is an indisputable fact of enormous human sacrifices, millions of people who have fled their country and the destroyed country in the heart of the Middle East.…”
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22929
Immediate-Early Genes and Delayed Primary Response Genes Regulated by NmU in SKBR3 HER-2 Positive Breast Cancer Cell Line
Published 2019-09-01“…EGR1 and NR4A1 act as tumour suppressors in certain human cancers, suggesting that NmU may drive cancer progression by inhibiting important tumour suppressors. …”
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22930
Clinical Factors of Blood Transfusion-Related Acute Lung Injury and Changes in Levels of Treg-Related Cytokines
Published 2022-01-01“…The differences in smoking history, human leukocyte antigen (HLA) antibody II, pretransfusion shock, and CD4 + CD25 + Treg between the TRALI group and non-TRALI group were statistically significant (P<0.05). …”
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22931
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22932
Crimean-Ottoman Factor in the Socio-Cultural System of Russia in Early Modern Times
Published 2020-11-01“…At the same time, it not only did not share the fate of many eastern powers with a traditional way, which turned into the 17th-19th centuries in the colony and semi-colony, but also, on the contrary, it led a successful colonial expansion and demonstrated externally the almost synchronous trends in state building that were inherent in the Western European countries.The author believes that the patrimonial structure of the sociocultural system of the Russian state in the 15-17 centuries contributed to the mobilization of internal material and human resources, coupled with an early superficial “Europeanization” (regular borrowing the military, technical, and cultural experience of modernizing Western Europe), ensured Russia's competitiveness in the world. …”
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22933
La Mélancolie et l’aspect spatio-temporel de l’identité dans Le pion sur l’échiquier d’Irène Némirovsky
Published 2024-12-01“…After the age of doubt enshrouding human subjectivity during the postmodern period, the question of the subject is back on the table. …”
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22934
Development of Binocular Vision
Published 2014-01-01“…Normal binocular vision requires a clear visual axis, sensory fusion, and motoric fusion. In human, the sensitive period of binocular vision development began at around 3 months of age, reaching its peak at the age of 1 to 3 years, had developed completely at the age of 4 years and gradually declined until it stops at the age of 9 years. …”
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22936
Design of an Integrated Model for Video Summarization Using Multimodal Fusion and YOLO for Crime Scene Analysis
Published 2025-01-01“…Finally, a feedback-driven reinforcement learning framework named RL-HITL allows continuous improvement based on human input, which enhances the adaptability of the system over temporal instance sets. …”
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22937
circRNA_101277 Influences Cisplatin Resistance of Colorectal Cancer Cells by Modulating the miR-370/IL-6 Axis
Published 2022-01-01“…IL-6 levels were measured with a human IL-6 ELISA kit based on the provided protocols. …”
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22938
Dental problems and oral microbiome alterations in ulcerative colitis
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22939
Search for differentially methylated regions in ancient and modern genomes
Published 2023-12-01“…In this study, we attempted to develop an algorithm for identifying differentially methylated regions associated with metabolic syndrome, which have undergone methylation changes in humans during the transition from a huntergatherer to a sedentary lifestyle. …”
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22940
Predicting nighttime black ice using atmospheric data for efficient winter road maintenance patrols
Published 2025-01-01“…However, patrolling the entire road network on a daily basis requires substantial human and equipment resources. To address this issue, an approach to identify high-risk road sections and prioritize patrolling efforts on these selected sections needs to be established. …”
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