Clinical, histopathological and immunohistochemical analysis of vulvar squamous cell carcinoma by Lorenza Bridi Todeschini, Rita de Cássia Sant’Anna Alves, Adriana Vial Roehe

“…Abstract Objective: The average age of patients with vulvar squamous cell carcinoma (SCC) has been reported to have declined. Human papilloma virus (HPV)-related lesions have been shown to be associated with the expression of the immunohistochemical (IHC) marker p16. …”
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Analysis of algorithms for detecting traffic incidents on highways using stationary vehicle detectors by D. V. Navoi, D. V. Kapski, N. A. Filippova, I. N. Pugachev

“…Manual algorithms or procedures rely on reports from human witnesses. Based on functional characteristics, incident detection algorithms are divided into algorithms for highways and algorithms for street networks. …”
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Myeloid cell-derived apCAFs promote HNSCC progression by regulating proportion of CD4+ and CD8+ T cells by Feilong Ren, Lin Meng, Shize Zheng, Jiasen Cui, Shaoyi Song, Xing Li, Dandan Wang, Xing Li, Qilin Liu, Wenhuan Bu, Hongchen Sun

“…Significance: ApCAFs derived from myeloid cells promote the progression of HNSCC by increasing the ratio of CD4+/CD8+ cells, indicating potential novel targets to be used to treat the human HNSCC. Graphical Abstract…”
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Odor-active aroma compounds in traditional fermented dairy products: The case of mabisi in supporting food and nutrition security in Zambia by Thelma W. Sikombe, Anita R. Linnemann, Himoonga B. Moonga, Stefanie Quilitz, Sijmen E. Schoustra, Eddy J. Smid, Anna Alekseeva

“…A unique combination of specific compounds detectable by human olfactory senses creates the distinct odor profile of fermented products. …”
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Ozone exposure and cardiovascular disease: A narrative review of epidemiology evidence and underlying mechanisms by Qiaoyi Hua, Xin Meng, Jicheng Gong, Xinghua Qiu, Jing Shang, Tao Xue, Tong Zhu

“…Ozone (O3) poses a significant global public health concern as it exerts adverse effects on human cardiovascular health. Nevertheless, there remains a lack of comprehensive understanding regarding the relationships between O3 exposure and the risk of cardiovascular diseases (CVD), as well as the underlying biological mechanisms. …”
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THE EFFECT OF QUERCETIN ON MORPHOLOGICAL AND BIOCHEMICAL CHANGES IN RAT LIVER UNDER 270TH DAY CENTRAL DEPRIVATION OF LUTEINIZING HORMONE SYNTHESIS by M.V. Rud, V.I. Shepitko, Ye.V. Stetsuk, O.Ye. Akimov

“…Therefore, identifying the characteristics of these populations of human macrophages is of undeniable value in studying their role in the development of liver pathology. …”
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Provider Preference, Logistical Challenges, or Vaccine Hesitancy? Analyzing Parental Decision-Making in School Vaccination Programs: A Qualitative Study in Sydney, Australia by Leigh McIndoe, Alexandra Young, Cristyn Davies, Cassandra Vujovich-Dunn, Stephanie Kean, Michelle Dives, Vicky Sheppeard

“…This study investigates patterns of vaccine decision-making within Australia’s school-based immunization program, specifically focusing on human papillomavirus (HPV) and diphtheria-tetanus-pertussis (dTpa) vaccines offered free to adolescents aged 12–13. …”
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The Early Results of the Laparoscopic Mini-Gastric Bypass/One Anastomosis Gastric Bypass on Patients with Different Body Mass Index by Mohsen Mahmoudieh, Behrouz Keleidari, Naser Afshin, Masoud Sayadi Shahraki, Shahab Shahabi Shahmiri, Erfan Sheikhbahaei, Hamid Melali

“…Obesity is among the newest health matters that human beings are struggling with. Length of bypassed intestine is important in achievement of most weight loss and least nutritional and absorptive disorders. …”
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Ecosystem collaboration for climate action: a case study of the ILCA Project by Ancuța Agheniței, Carmen Nastase, Carmen Chașovschi

“…In recent years, the number of initiatives dealing with climate change has increased significantly as human activity releases more and more greenhouse gases into the environment. …”
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Influence of breed and environment on leukocyte telomere length in cattle by N. S. Yudin, A. V. Igoshin, G. A. Romashov, A. A. Martynov, D. M. Larkin

“…Telomeres are elements found at the ends of chromosomes, consisting of repetitive DNA sequences, several thousand base pairs in length, coupled with nucleoprotein complexes. Eventually, in humans and most other animals, telomere length reduces with age. …”
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Protection of liver sinusoidal endothelial cells using different preservation solutions by Julia H E Houtzager, Anne-Marieke van Stalborch, Charlotte Hofstee, Thomas M van Gulik, Jaap D van Buul

“…Therefore, the present study aimed to determine optimal preservation of LSEC barrier function and integrity using different preservation solutions. Human umbilical vein endothelial cells (HUVECs) and LSECs were incubated in either University of Wisconsin machine perfusion solution (UW-MPS), histidine-tryptophan-ketoglutarate, or endothelial cell growth medium 2 (EGM2) (as a gold standard for cell culturing). …”
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Concentration and health risk assessment of toxic metals in giblets of free-range chickens in Lokoja, Nigeria by Jude Ehwevwerhere Emurotu, Tenimu Adogah Abubakar, Loveth Chukwu, Queen Ese Umudi, Victory Imokan Imumorin, Gloria D. Paul, Grace Unekwuojo Oboni

“…Background: Potentially toxic metals present in food and food products are a threat to humans. To monitor the quality of giblets consumed and to evaluate the risk to the public's health, this study aimed to determine the residual concentrations of heavy metals (Al, As, Cd, Cr, Mn, Ni, Pb and Zn) in the gizzard, kidney, and liver of free-range chickens. …”
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Postoperative Pulmonary Hemodynamics and Systemic Inflammatory Response in Pediatric Patients Undergoing Surgery for Congenital Heart Defects by Maria Francilene S. Souza, Juliano G. Penha, Nair Y. Maeda, Filomena R. B. G. Galas, Kelly C. O. Abud, Eloisa S. Carvalho, Ana Maria Thomaz, Claudia R. P. Castro, Juliana Pereira, Antonio Augusto Lopes

“…Compared with patients with PAP/SAPIPO≤0.40 (n=22), those above this level (n=18) had increased pre- and postoperative serum levels of granulocyte colony-stimulating factor (p=0.040), interleukin-1 receptor antagonist (p=0.020), interleukin-6 (p=0.003), and interleukin-21 (p=0.047) (panel for 36 human cytokines) and increased mean platelet volume (p=0.018). …”
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Identification of compounds against atherosclerosis induced by ox-LDL based on cell extraction/UPLC–MS/MS from mulberry twigs and their mechanistic analysis by Zhihui Jin, Wei Xiang, Xiaowen Shi, Fenglin Jiang, Yanan Jia, Yuansong Zhang, Lingshu Zeng, Xianzhi Huang, Li Xu

“…This study aims to identify and evaluate the effects of key compounds in mulberry twig extracts (MTEs) on oxidized low-density lipoprotein (ox-LDL)-induced human umbilical vein endothelial cells (HUVECs), with a focus on understanding how these compounds modulate oxidative stress and related signaling pathways. …”
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Molecular effects of clinically relevant chemotherapeutic agents on choline phospholipid metabolism in triple negative breast cancer cells by Caitlin M. Tressler, Kanchan Sonkar, Menglin Cheng, Vinay Ayyappan, Ruoqing Cai, Kristine Glunde

“…We sought to further investigate these clinical observations at the molecular level by combining metabolic and transcriptomic studies in two human TNBC cell lines treated with six different chemotherapeutic agents. …”
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First Molecular Identification of <i>Entamoeba</i> spp. in Sheep, Beef Cattle, and Dairy Cattle in Shanxi Province, North China by Ze-Xuan Wu, Han-Dan Xiao, Yuan-Hui He, Shi-Bo Huang, Jing Li, Yu Kang, Wen-Bin Zheng, Xing-Quan Zhu

“…<i>Entamoeba</i> spp. are common zoonotic intestinal protozoa, which can lead to serious intestinal diseases in both humans and animals through fecal–oral transmission, leading to significant economic losses and public health challenges. …”
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TARREAN: A Novel Transformer with a Gate Recurrent Unit for Stylized Music Generation by Yumei Zhang, Yulin Zhou, Xiaojiao Lv, Jinshan Li, Heng Lu, Yuping Su, Honghong Yang

“…The results show that our model produces music that is more aligned with human preferences, as indicated by subjective evaluation scores. …”
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Key regions aberrantly connected within cerebello-thalamo-cortical circuit and their genetic mechanism in schizophrenia: an fMRI meta-analysis and transcriptome study by Yarui Wei, Ziyu Wang, Kangkang Xue, Xiaoyu Niu, Longyao Ma, Shaoqiang Han, Baohong Wen, Yong Zhang, Huafu Chen, Jingliang Cheng

“…Gene annotation analysis was performed to identify genes over-expressed in these regions by using the Allen Human Brain Atlas, followed by a set of gene functional feature analyses. 19 studies (1333 patients and 1174 healthy controls) were included in this meta-analysis. …”
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Contaminant-degrading bacteria are super carriers of antibiotic resistance genes in municipal landfills: A metagenomics-based study by Fang-Zhou Gao, Wei-Li Jia, Bing Li, Min Zhang, Liang-Ying He, Hong Bai, You-Sheng Liu, Guang-Guo Ying

“…Results showed that the antibiotic resistome in landfills contained 1,403 ARG subtypes, with the total abundance over the levels in natural environments and reaching the levels in human feces and sewage. Therein, 49 subtypes were listed as top priority ARGs for future surveillance based on the criteria of enrichment in landfills, mobilizable and present in pathogens. …”
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Risk Evaluation of Pyrolyzed Biochar from Multiple Wastes by Shem M. Ndirangu, Yanyan Liu, Kai Xu, Shaoxian Song

“…These toxic compounds formed pose a threat to human health through the food chain. Determination of toxicity levels is a first step in the risk management of toxic biochar. …”
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