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22501
Mucosal Epithelial Jak Kinases in Health and Diseases
Published 2021-01-01“…Among Jaks, Jak3 is widely expressed in both immune cells and in intestinal epithelial cells (IECs) of both humans and mice. Mutations that abrogate Jak3 functions cause an autosomal severe combined immunodeficiency disease (SCID) while activating Jak3 mutations lead to the development of hematologic and epithelial cancers. …”
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22502
Assessment of Knowledge and Practice of Various Eye Diseases in Sulaimani: A Descriptive Study
Published 2018-07-01“…Knowledge and practice of public, especially patients about eye diseases are important to reduce magnitude of human blindness. Vision and sight are very essential because they allow us to connect to each other’s. …”
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22503
Investigating the Effectiveness of Coal-Fired Power Plant Operations: Management, Technical and Air Pollution Aspects
Published 2025-02-01“…The model indicates that verifying the standard operating procedure (SOP) is crucial for improving power generation efficiency and reducing human error (R²=0.914). This study pinpoints issues reducing power plant efficiency, particularly regarding emissions, and shows that the regression model is strong (R² = 0.916–0.647). …”
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22504
Cell-Free miR-27a, a Potential Diagnostic and Prognostic Biomarker for Gastric Cancer
Published 2015-09-01“…Previous studies revealed that miRNAs are present in human plasma in a remarkably stable form that is protected from endogenous RNase activity. …”
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22505
Integrated strategies for effective remediation of chromium-contaminated soils: Advancements, challenges, and sustainability implications
Published 2025-04-01“…Soil chromium contamination represents a significant global environmental challenge, posing serious risks to human health and ecosystems. The toxicity of hexavalent chromium, in particular, underscores the need for effective remediation strategies to mitigate its harmful effects. …”
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22506
Monocytes serve as Shiga toxin carriers during the development of hemolytic uremic syndrome
Published 2025-01-01“…Remarkably, Stx-laden monocytes demonstrate their ability to transport Stx2 to human renal glomerular endothelial cells (HRGEC), subsequently inducing apoptosis in HRGEC. …”
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22507
Characteristic Fe and Cu Compounds in Particulate Matter from Subway Premises in Japan and their Potential Biological Effects
Published 2024-12-01“…The potential biological effects of these chemical states on humans were also investigated in vitro by assessing cell damage and its pathways in cells after exposure to several compounds. …”
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22508
Designing a Model of Effective Factors on Creative Cultural Industries in Iran
Published 2022-11-01“…These factors were ranked, and the criteria' importance from the first to the third were structural and human capital, required infrastructure, and government support.Originality/Value: By generating new needs, creative cultural industries can produce new cultural consumers and increase cultural accumulation, which requires promoting cultural capital in society by intensifying cultural uses. …”
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22509
Effects of meteorological factors on the retention of particulate matter in lawn grass blades
Published 2025-01-01“…Plant leaves can reduce the concentration of atmospheric particulate matter (PM) by absorbing it in the air, and this mitigates the deleterious human health effects of PM. However, the ability of plant leaves to retain dust is limited and varies continually due to various meteorological factors such as rainfall, extreme wind speed, and PM10 concentrations. …”
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22510
The role of Akkermansia muciniphila in maintaining health: a bibliometric study
Published 2025-02-01“…The most cited articles deepened the understanding of the bacterium’s impact on human health, spanning from basic research to translational medicine. …”
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22511
Screening of the Dichloromethane: Methanolic Extract of Centella asiatica for Antibacterial Activities against Salmonella typhi, Escherichia coli, Shigella sonnei, Bacillus subtili...
Published 2020-01-01“…They included preliminary screening of dichloromethane: methanolic extract of Centella asiatica against human pathogenic bacteria including Salmonella typhi ATCC 19430, Escherichia coli ATCC 25922, Shigella sonnei ATCC 25931, Bacillus subtilis ATCC 21332, and Staphylococcus aureus ATCC 25923 using agar disc diffusion, broth microdilution method, and time-kill kinetics with tetracycline as a positive control. …”
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22512
RNAI-MEDIATED SILENCING OF MATRIX METALLOPROTEINASE 1 IN EPIDERMAL KERATINOCYTES INFLUENCES THE BIOLOGICAL EFFECTS OF INTERLEUKIN 17A
Published 2018-07-01“…The aim of this study was to explore how MMP1 silencing might influence the biological effects of IL-17A on migration and proliferation of human epidermal keratinocytes and the expression of genes involved in their division and differentiation. …”
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22513
Effect of epigallocatechin-3-gallate (EGCG) on cognitive functioning and the expression of APP and BDNF in the hippocampus of rats with streptozotocin -induced Alzheimer-like disea...
Published 2025-03-01“…These findings could provide a beneficial insight for developing novel, safe, and efficient natural compounds for preventing or alleviation AD symptoms in humans.…”
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22514
Characterization of a chemically induced osteoarthritis model in zebrafish
Published 2025-01-01“…Consequently, this offers a fresh avenue for investigating the pathogenesis, prevention, and potential therapeutic approaches for human OA.…”
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22515
mtSTAT3 suppresses rheumatoid arthritis by regulating Th17 and synovial fibroblast inflammatory cell death with IL-17-mediated autophagy dysfunction
Published 2025-01-01“…The abnormal accumulation of autophagosomes and the expression of inflammatory cell death factors were also decreased in these mice. In mouse and human immune cells, ZnSO4, an inducer of mitochondrial STAT3, decreases the production of reactive oxygen species, the IL-17 concentration, and differentiation into Th17 cells. …”
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22516
Seroprevalence and Potential Risk Factors of Toxocariasis among General Population in Southwest Iran: Implications on the One Health Approach
Published 2024-01-01“…Further comprehensive studies with a focus on humans and animals should be designed in different areas of the Province. …”
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22517
Computational Study of the Phytochemical Constituents from Uncaria tomentosa Stem Bark against SARS-CoV-2 Omicron Spike Protein
Published 2022-01-01“…On the other hand, medicinal plants have been used as alternatives therapies to ameliorate some signs and symptoms in COVID-19, and in our previous work, the cat’s claw (Uncaria tomentosa) stem bark has been studied in vitro and showed antiviral activity on SARS-CoV-2 as well as in silico studies on the 3CLpro protein and as disruptor between the ACE-2 human receptor and the spike protein. The aim in this computational study was to determine the main phytochemical constituents from U. tomentosa stem bark against the SARS-CoV-2 Omicron spike protein based on molecular modeling. …”
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22518
Photocatalytic Degradation of Trifluralin in Aqueous Solutions by UV/S2O82− and UV/ZnO Processes: A Comparison of Removal Efficiency and Cost Estimation
Published 2021-01-01“…Trifluralin is one of the most widely used herbicides, being accounted as the cause of cancer in human. In the present research, the UV/S2O82− and ZnO/UV processes’ efficiency in the removal of trifluralin was investigated. …”
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22519
Impact of sleep quality on academic achievements of undergraduate medical students: a cross-sectional study from Saudi Arabia
Published 2025-01-01“…Abstract Background Sleep is an active process that affects human health and quality of life. Sleep is essential for learning and memory consolidation. …”
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22520
The effectiveness of rural community health workers in improving health outcomes during the COVID-19 pandemic: a systematic review
Published 2024-12-01“…There is a need to focus on rural CHWs and rural health systems as they have limited material and human resources rendering them more vulnerable than urban health systems to severe disruptions during pandemics. …”
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