Magnetoelectric Extracellular Vesicle Latency-Targeting (MELT) Nanotherapeutic for the Block-Lock-and-Kill HIV Eradication Strategy by Mickensone Andre, Nagesh Kolishetti, Adriana Yndart, Arti Vashist, Madhavan Nair, Andrea D. Raymond

“…Background: Human immunodeficiency virus (HIV) establishes latent infections in cellular reservoirs, including microglia. …”
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An automated platform for simultaneous, longitudinal analysis of engineered neuromuscular tissues for applications in neurotoxin potency testing by Jacob W. Fleming, Molly C. McCloskey, Kevin Gray, David R. Nash, Vincent Leung, Christos Michas, Shawn M. Luttrell, Christopher Cavanaugh, Julie Mathieu, Shawn Mcquire, Mark Bothwell, David L. Mack, Nicholas A. Geisse, Alec S.T. Smith

“…Animal models of the neuromuscular junction (NMJ) have been widely studied but exhibit critical differences from human biology limiting utility in drug and disease modelling. …”
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Probiotic Amelioration of Azotemia in 5/6th Nephrectomized Sprague-Dawley Rats by Natarajan Ranganathan, Beena Patel, Pari Ranganathan, Joseph Marczely, Rahul Dheer, Tushar Chordia, Stephen R. Dunn, Eli A. Friedman

“…Derivative trials of probiotic treatment of larger animals and humans will further assess the potential role of probiotic formulations in delaying the onset and clinical severity of clinical illness at different stages of renal failure.…”
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Patients with colorectal cancer combined with HIV had a worse overall survival after surgery: a meta-analysis by Wen-Wen Yang, Wen-Wen Yang, Xiong Zhou, Gan He

“…PurposeThe purpose of this current study was to find out whether human immunodeficiency virus (HIV) affected overall survival (OS) of colorectal cancer (CRC) patients after surgery.MethodsPubMed, Embase, the Cochrane Library, and CNKI were searched from inception to March 27, 2023 to find eligible studies. …”
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An Interdisciplinary Analysis of the Late Islamic Cemeteries Within the Cathedral (15th–18th Century CE) and the Ruins of Adulis (Mid-19th–Early 20th Century CE), Massawa, Eritrea:... by Omar Larentis, Nelly Cattaneo, Paolo Lampugnani, Susanna Bortolotto, Emanuele Zappa, Andrea Gregorini, Yotam Gezae, Tsegai Medin, Ilaria Gorini, Serena Massa

“…These discoveries have enabled, for the first time in Eritrea, a detailed scientific study of the biological characteristics of the human remains, the funerary architecture, and the burial rites of Muslim communities from the 15th to the early 20th century. …”
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Impact of sex on the adaptation of adult mice to long consumption of sweet-fat diet by N. M. Bazhan, T. V. Iakovleva, A. D. Dubinina, E. N. Makarova

“…In rodents, the most adequate model of human diet-induced obesity is obesity caused by the consumption of a sweet-fat diet (SFD), which causes more pronounced adiposity in females than in males. …”
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An evaluation of osseous regeneration capability of novel autogenous tooth graft along with orthobiologics for long bone segmental defects by N. Hussain, M.A. Khan, A.K. Mahmood, M.Y. Tipu, S. Aslam

“…Though usage of aforementioned regimens in-vivo needs further trials but overall, we may suggest that autogenous tooth is not only a novel and viable graft in solo but its healing capacity, osteointegration and firm callus formation can be augmented with appropriate orthobiologic materials and in future may be useful for bone defect treatments, not only in animals but humans as well.…”
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Health and Educational Inequalities among the Third Gender Community in Lahore, Pakistan by Ayesha Humayun, Muhammad Hassan, Hira Ashfaq, Zulqarnain Haider, Nauman Naeem, Mubashar Munir

“…Conclusion: The third gender community faces significant barriers in accessing education and healthcare, depriving them of basic human rights. Urgent policy reforms promoting equity, inclusivity, and community sensitization are needed to end their social neglect. …”
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Spirituality of HIV-infected female patients treated in a secondary care hospital in Thailand: a preliminary investigation by Natawan Khumsaen, Panarat Chenchob, Supannee Peawnalaw

“…Introduction Globally, acquired immune deficiency syndrome (AIDS) and human immunodeficiency virus (HIV) infection are major public health concerns. …”
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Clinical profile and outcomes analysis of HIV infection by Ashwant Kumar, Yoganathan Chidambaram, Clement J. Dhas, Nekkanti Abilash, Murali Alagesan

“…Background India has the third largest number of human immunodeficiency virus (HIV) patients, but the national prevalence is continuously receding owing to dedicated health centers as well as highly active antiretroviral therapy (HAART), which is associated with newer manifestations and outcomes. …”
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Meta-Analysis of Integrated Therapeutic Methods in Noninvasive Lower Back Pain Therapy (LBP): The Role of Interdisciplinary Functional Diagnostics by Aleksandra Bitenc-Jasiejko, Krzysztof Konior, Danuta Lietz-Kijak

“…Quite often, it is a consequence of many years of disturbed distribution of tension within the human body caused by local conditions (injuries, hernias, stenoses, spondylolisthesis, cancer, etc.), global factors (postural defects, structural integration disorders, lifestyle, type of activity, etc.), or systemic diseases (connective tissue, inflammation, tumours, abdominal aneurysm, and kidney diseases, including urolithiasis, endometriosis, and prostatitis). …”
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Spatial and temporal characteristics and driving mechanisms of recreational ecosystem services supply-demand mismatch in rapidly urbanizing areas: Evidence from the Yangtze River D... by Ruien Tang, Guolin Hou, Yueyi Chen, Xiao Liu, Shaoying Chu, Li Li

“…Understanding the spatial and temporal processes of Recreational Ecosystem Services (RES) supply–demand matching and their driving mechanisms is essential for the enhancement of human well-being and the sustainable management of socio-ecological systems in the region. …”
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Assessing the factors affecting the formation of entrepreneurial opportunities in rural areas; Case study: Behbahan County by sara ferdosi, hasanali faraji sabokbar, alireza darbaneh astaneh, fazileh khani

“…The development of sustainable entrepreneurship plays a critical role in promoting human well-being and environmental preservation. …”
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Mediterranean diet improves liver health but does not protect against azoxymethane-induced colon tumorigenesis compared to Western diet in A/J mice by Weimin Guo, Nicholas Crossland, Jimmy W. Crott

“…Conclusion: In this study male mice displayed elevated sensitivity to AOM-induced hepatotoxicity and mortality than females. In agreement with human and preclinical data, livers of MED-diet-fed mice were healthier than those fed WRN diets. …”
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Tear metabolomics reveals novel potential biomarkers in epithelial herpes simplex keratitis by Jinyu Zhang, Zhenning Wu, Yangqi Zhang, Kaili Wu, Xiaoyi Li, Shiyou Zhou

“…Metabolites were quantified and matched against entries in the human metabolome database (HMDB) and small molecule pathway database (SMPDB) to identify metabolites and metabolic pathways, respectively. …”
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Isolation, Characterization, and Quantification of Bacteria from African Sausages Sold in Nairobi County, Kenya by W. H. Karoki, D. N. Karanja, L. C. Bebora, L. W. Njagi

“…This study has demonstrated presence of bacteria in African sausages which are potentially zoonotic to humans. Comprehensive study is needed to sample more eatery meat points in Nairobi and other areas in order to demonstrate pathogenic attributes of these isolates and establish the respective total aerobic bacterial count. …”
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Functional Skin Grafts: Where Biomaterials Meet Stem Cells by Amtoj Kaur, Swati Midha, Shibashish Giri, Sujata Mohanty

“…However, there is still a long way before an artificial skin substitute can fully mimic the functions and anatomical hierarchy of native human skin. The current focus of skin tissue engineers is primarily to develop a 3D construct that maintains the functionality of cultured cells in a guided manner over a period of time. …”
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A global Corynebacterium diphtheriae genomic framework sheds light on current diphtheria reemergence by Hennart, Mélanie, Crestani, Chiara, Bridel, Sébastien, Armatys, Nathalie, Brémont, Sylvie, Carmi-Leroy, Annick, Landier, Annie, Passet, Virginie, Fonteneau, Laure, Vaux, Sophie, Toubiana, Julie, Badell, Edgar, Brisse, Sylvain

“…Methods: We developed the bioinformatics pipeline diphtOscan (available at https://gitlab.pasteur.fr/BEBP/diphtoscan) to extract from genomes of Corynebacteria of the diphtheriae species complex, medically relevant features including tox gene presence and disruption. We analyzed 101 human C. diphtheriae isolates collected in 2022 in metropolitan and overseas France (France-2022). …”
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Intrahepatic levels of microbiome-derived hippurate associates with improved metabolic dysfunction-associated steatotic liver disease by Maxime Deslande, Francesc Puig-Castellvi, Inés Castro-Dionicio, Romina Pacheco-Tapia, Violeta Raverdy, Robert Caiazzo, Guillaume Lassailly, Audrey Leloire, Petros Andrikopoulos, Yasmina Kahoul, Nawel Zaïbi, Bénédicte Toussaint, Frédérik Oger, Nicolas Gambardella, Philippe Lefebvre, Mehdi Derhourhi, Souhila Amanzougarene, Bart Staels, François Pattou, Philippe Froguel, Amélie Bonnefond, Marc-Emmanuel Dumas

“…Hippurate, a host-microbial co-metabolite has been associated with human gut microbial gene richness and with metabolic health. …”
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Biological effectiveness of combined exposure to neutrons and gamma radiation applied in two orders of sequence: Relevance for biological dosimetry after nuclear emergencies by Tomas Palmqvist, Milagrosa Lopez-Riego, Martin Bucher, Ursula Oestreicher, Stefan Pojtinger, Ulrich Giesen, Iuliana Toma-Dasu, Andrzej Wojcik

“…Methods: Whole blood from 3 human donors was exposed to neutrons with an energy spectrum similar to that of the Hiroshima uranium bomb, to gamma radiation from a 60Co source and to a 50:50 combination of both radiations, given in two orders of sequence. …”
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