Tissue-specific effects of benzo[a]pyrene and DDT on microRNA expression profile in female rats by D. S. Ushakov, T. S. Kalinina, A. S. Dorozhkova, V. Y. Ovchinnikov, L. F. Gulyaeva

“…Many xenobiotics in the human environment, such as benzo[a]pyrene (B(a)P) and dichlorodiphenyltrichloroethane (DDT), may act as non-genotoxic carcinogens through epigenetic mechanisms, including changes in microRNA expression profile. …”
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The weight-adjusted-waist index predicts all-cause and cardiovascular mortality in hypertension by Yu Zheng, Zixing Nie, Yifan Zhang, Tao Sun

“…BackgroundWeight-adjusted-waist (WWI) is a novel indicator of obesity that reflects the degree of central obesity in the human body.ObjectivesThe study aimed to explore the relationship between WWI and mortality in hypertensive individuals.MethodsCross-sectional data from the 2001–2018 National Health and Nutrition Examination Survey (NHANES) dataset were used in this study. …”
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Positive association between chronic hepatitis B virus infection and anemia in pregnancy in Southern China by Renliang Huang, Zhe Lu, Xinze Li, Duo Zhou, Jing Xu, Dan Lin, Yunxue Fu, Yan Liang, Xuexia Li, Frank Petersen, Qiaomiao Zhou, Xinhua Yu

“…Comparison between women with and without anemia in pregnancy revealed significant differences between the two groups concerning age, gestational diabetes, hypothyroidism, hyperthyroidism, chronic hepatitis B virus infection, syphilis infection, and human immunodeficiency virus infection. Multivariable logistic regression analysis showed that chronic hepatitis B virus infection was significantly associated with anemia during pregnancy (AOR   2.97, 95% CI 2.57–3.44, p < 0.0001). …”
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The Perceptions and Attitudes of Residents Towards Urban Green Spaces in Emilia-Romagna (Italy)—A Case Study by Zhengyang Xu, Teodoro Georgiadis, Letizia Cremonini, Sofia Marini, Stefania Toselli

“…Rapid urbanisation has highlighted the importance of urban green spaces (UGS) in promoting environmental sustainability and human wellbeing, yet the gap between urban planning practices and community preferences remains a significant challenge. …”
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Outer retina micro-inflammation is driven by T cell responses prior to retinal degeneration in early age-related macular degeneration by Lucas Stürzbecher, Lucas Stürzbecher, Lucas Stürzbecher, Lucas Stürzbecher, Hendrik Bartolomaeus, Hendrik Bartolomaeus, Hendrik Bartolomaeus, Hendrik Bartolomaeus, Theda U. P. Bartolomaeus, Theda U. P. Bartolomaeus, Theda U. P. Bartolomaeus, Theda U. P. Bartolomaeus, Sylvia Bolz, Andjela Sekulic, Marius Ueffing, Marius Ueffing, Simon J. Clark, Simon J. Clark, Simon J. Clark, Nadine Reichhart, Sergio Crespo-Garcia, Nicola Wilck, Nicola Wilck, Nicola Wilck, Nicola Wilck, Olaf Strauß

“…Dysfunction of the retinal pigment epithelium (RPE) is a unifying salient feature of the pathology and a primary end-point damage leading to complications such as geographic atrophy (GA), which represents the most common end-stage of AMD.MethodsHuman and murine ocular tissues were used for histological examinations. …”
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Estimating the impact of the Mongol expansion upon the gene pool of Tuvans by L. D. Damba, Е. V. Balanovskaya, M. K. Zhabagin, Y. М. Yusupov, Y. V. Bogunov, Z. M. Sabitov, A. T. Agdzhoyan, N. A. Korotkova, M. B. Lavryashina, B. B. Mongush, U. N. Kavai-ool, O. P. Balanovsky

“…With a view to trace the Mongol expansion in Tuvinian gene pool we studied two largest Tuvinian clans – those in which, according to data of humanities, one could expect the highest Central Asian ancestry, connected with the Mongol expansion. …”
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Effectiveness of nurse-led volunteer support and technology-driven pain assessment in improving the outcomes of hospitalised older adults: protocol for a cluster randomised control... by Max K Bulsara, Christopher Etherton-Beer, Rosemary Saunders, Kate Crookes, Mustafa Atee, Caroline Bulsara, Beverley Ewens, Olivia Gallagher, Renee M Graham, Karen Gullick, Sue Haydon, Kim-Huong Nguyen, Bev O'Connell, Karla Seaman, Jeff Hughes, Seng Giap Marcus Ang, Debra Scaini

“…Stakeholder evaluation and an economic analysis of the interventions will also be conducted.Ethics and dissemination Ethical approval has been granted by Human Research Ethics Committees at Ramsay Health Care WA|SA (number: 2057) and Edith Cowan University (number: 2021-02210-SAUNDERS). …”
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Constitutive expression of Cas9 and rapamycin-inducible Cre recombinase facilitates conditional genome editing in Plasmodium berghei by Samhita Das, Tanaya Unhale, Carine Marinach, Belsy del Carmen Valeriano Alegria, Camille Roux, Hélène Madry, Badreddine Mohand Oumoussa, Rogerio Amino, Shiroh Iwanaga, Sylvie Briquet, Olivier Silvie

“…Among various such strategies, the rapamycin-inducible dimerisable Cre (DiCre) recombinase system emerged as a powerful approach for conditional editing of essential genes in human-infecting P. falciparum and in the rodent malaria model parasite P. berghei. …”
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Helminth diversity of nutria (Myocastor coypus) across the Morava basin in the Czech Republic by Michal Benovics, Eva Nosková, Anna Klimešová, Lucie Škorpíková, Ema Jaššová, Jakub Drimaj, Jan Slováček, Ondřej Mikulka

“…Although the nutria is a relatively new species in local fauna, its synanthropic behaviour raises concerns about potential threats to human health, underscoring the importance of exercising caution when handling these animals.…”
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Risk Assessment of Non-Point Source Pollution Based on the Minimum Cumulative Resistance Model: A Case Study of Shenyang, China by Yongxin Wang, Jianmin Qiao, Yuanman Hu, Qian Zhang, Xiulin Han, Chunlin Li

“…Urban non-point source (NPS) pollution is an important risk factor that leads to the deterioration of urban water quality, affects human health, and destroys the ecological balance of the water environment. …”
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Comprehensive three-dimensional microCT and signaling analysis reveal the teratogenic effect of 2,3,7,8-tetrachlorodibenzo-p-dioxin on craniofacial bone development in mice by Xiao-ming Wang, Cai-ming Qin, Dou Li, Xin-ran Xu, Xiao-jing Pan, Hui Xue

“…Further in vitro determination of the underlying mechanisms using human fetal palatal mesenchymal cells (hFPMCs) revealed that TCDD suppressed a wide variety of osteogenic genes responsible for osteoblast commitment and bone matrix synthesis and mineralization, through activating aryl hydrocarbon receptor (AhR) signaling and subsequently inhibiting estrogen signaling. …”
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Future Changes in Winter‐Time Extratropical Cyclones Over South Africa From CORDEX‐CORE Simulations by Sandeep Chinta, C. Adam Schlosser, Xiang Gao, Kevin Hodges

“…We utilized three regional climate models, each driven by three different global climate models that simulate both the current climate and a future climate experiencing strong human‐induced warming. From these, we assess changes in ETC frequency, track density, intensity, storm severity, and associated rainfall. …”
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The combined effectiveness of acoustic indices in measuring bird species richness in biodiverse sites in Cyprus, China, and Australia by Christos Mammides, Pan Wuyuan, Guohualing Huang, Rachakonda Sreekar, Christina Ieronymidou, Aiwu Jiang, Eben Goodale, Harris Papadopoulos

“…Human activities are accelerating biodiversity loss, necessitating tools capable of monitoring biodiversity patterns over large spatial and temporal scales. …”
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Object Placement Across Robotics, Image Composition, and XR: A Mixed Reality Framework Proposal by Jalal Safari Bazargani, Abolghasem Sadeghi-Niaraki, Soo-Mi Choi

“…A framework for object placement in MR environments is proposed, which integrates geometric and semantic representations, a human-in-the-loop approach, and real-time interaction features. …”
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Development and Validation of LAMP Assays for Distinguishing MPXV Clades with Fluorescent and Colorimetric Readouts by Nazente Atceken, Sara Asghari Dilmani, Ahmed Choukri Abdullah, Mutlu Sarıkaya, Defne Yigci, Gozde Korkmaz, Savas Tasoglu

“…Human monkeypox (Mpox) is a zoonotic disease caused by the Monkeypox virus (MPXV). …”
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Increased Expression of the Pro-Protein Convertase Furin Predicts Decreased Survival in Ovarian Cancer by Robert E. Page, Andrés J. P. Klein-Szanto, Samuel Litwin, Emmanuelle Nicolas, Raid Al-Jumaily, Peter Alexander, Andrew K. Godwin, Eric A. Ross, Russell J. Schilder, Daniel E. Bassi

“…Methods: We assessed their expression by RT-PCR, Real-time PCR, Western blot, and immunohistochemistry using cells derived from normal human ovarian surface epithelium (HOSE) and cancer cell lines as well as ovarian epithelial cancer specimens (45 RT-PCR/Real-time PCR, and 120 archival specimens for Immunohistochemistry). …”
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Archaeological Site Detection: Latest Results from a Deep Learning Based Europe Wide Hillfort Search by Jürgen Landauer, Simon Maddison, Giacomo Fontana, Axel G. Posluschny

“…While automation significantly reduces manual workload, human verification remains critical for refining AI predictions and addressing false positives. …”
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Endogenous IL-33 Deficiency Exacerbates Liver Injury and Increases Hepatic Influx of Neutrophils in Acute Murine Viral Hepatitis by Virginie Carrière, Muhammad Imran Arshad, Jacques Le Seyec, Benjamin Lefevre, Muhammad Farooq, Aurélien Jan, Christelle Manuel, Laurence Touami-Bernard, Catherine Lucas-Clerc, Valentine Genet, Hugues Gascan, Jean-Philippe Girard, Frédéric Chalmel, Lucie Lamontagne, Claire Piquet-Pellorce, Michel Samson

“…The alarmin IL-33 has been described to be upregulated in human and murine viral hepatitis. However, the role of endogenous IL-33 in viral hepatitis remains obscure. …”
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Nonylphenol exposure increases the risk of Hirschsprung’s disease by inducing macrophage M1 polarization by Xuefeng Yang, Chengyan Tang, Daiwei Zhu, Xingrong Xia, Qing Du, Lu Huang, Jianguo Liu, Yuanmei Liu

“…Our results showed that NP concentration and LINC00294 were significantly associated with HSCR occurrence and macrophage polarization in human HSCR specimens. Moreover, NP promoted macrophage M1 polarization. …”
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Electroencephalography Correlation of Ketamine-induced Clinical Excitatory Movements: A Systematic Review by Emine M. Tunc, Neil Uspal, Lindsey Morgan, Sue L. Groshong, Julie C. Brown

“…Two independent reviewers assessed papers based on eligibility criteria, which included human studies where EEG recordings were obtained during ketamine administration. …”
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