Investigation of groundwater quality indices and health risk assessment of water resources of Jiroft city, Iran, by machine learning algorithms by Sobhan Maleky, Maryam Faraji, Majid Hashemi, Akbar Esfandyari

“…Abstract Assessing water quality is essential for acquiring a better understanding of the importance of water in human society. In this study, the quality of groundwater resources in Jiroft city, Iran, using artificial intelligence methods to estimate the groundwater quality index (GWQI) was evaluated. …”
Get full text

MGScoliosis: Multi-grained scoliosis detection with joint ordinal regression from natural image by Xiaojia Zhu, Rui Chen, Zhiwen Shao, Ming Zhang, Yuhu Dai, Wenzhi Zhang, Chuandong Lang

“…Extensive experiments demonstrate that our approach outperforms state-of-the-art methods as well as human performance, which provides a promising and economical solution to wide-range scoliosis screening. …”
Get full text

Current Status of Canine Umbilical Cord Blood-Derived Mesenchymal Stem Cells in Veterinary Medicine by Tania Sultana, Soojung Lee, Hun-Young Yoon, Jeong Ik Lee

“…Although MSCs have been isolated from UCB of diverse species such as human, equine, sheep, goat, and canine, there are inherent limitations of using UCB from these species for the expansion of MSCs. …”
Get full text

Meta-analysis on the entomological effects of differentially treated ITNs in a multi-site experimental hut study in sub-Saharan Africa by Natalie Lissenden, John Bradley, Benjamin Menze, Charles Wondji, Constant Edi, Benjamin Koudou, Raphael N’Guessan, Koama Bayili, Abdoulaye Diabaté, Njelembo Mbewe, Basiliana Emidi, Jacklin Mosha, Alphaxard Manjurano, Graham Small, Welbeck Oumbouke, Sarah Jane Moore, Derric Nimmo, Janneke Snetselaar

“…These trials were conducted on a range of net products with different AIs, across a range of geographies in Africa (East and West), vector species (Anopheles gambiae, Anopheles coluzzii, Anopheles arabiensis, and Anopheles funestus), hut designs (East and West African style) and hosts (cows and humans). The combined data from these trials were analysed in a meta-analysis, and odds ratios for the effect of the different net designs on mortality and blood-feeding were estimated using mixed effects logistic regression. …”
Get full text

EFFORTS IN CONTROLLING COAL DUST HAZARDS IN THE STOCKPILE AREA OF A STEAM POWER PLANT (PLTU) by Alifiah Rizky Rosydah, Y. Denny Ardyanto Wahyudiono, Ahmad Imaduddin, Dani Nasirul Haqi, Meirina Ernawati

“…The smaller the particle size, the more harmful effects it can have on human health, such as bronchitis, decreased lung function, Chronic Obstructive Pulmonary Disease (COPD), Coal Worker's Pneumoconiosis (CWP), and other respiratory diseases. …”
Get full text

Anti-Apoptosis Effects of Green Tea in Diagnostic and Therapeutic Doses of Ionizing Radiation by Najmeh Anbiaee, Mohammad Taghi Bahreyni Toossi, Hosein Azimian, Zoha Sahebnasagh, Sepideh Abdollahi Dehkordi, Majid Kianmehr, samaneh soudmand salarabadi, Maryam Najafi Amiri

“…The aim of the present study is assessing the protective effect of green tea on lymphocytes affected by radiation injury.Material and Methods: Blood samples was obtained from four adults healthy human and lymphocytes were extracted. Afterward, lymphocytes were exposed to X-radiation by OPG, CBCT, CT and radiotherapy instruments. …”
Get full text

Does welfare technology contribute to security, activity, participation and independence within municipal elder care? A qualitative study protocol by Ingrid Hellström, Johannes Österholm, Åsa Larsson Ranada, Katarina Baudin, Vedrana B Baric

“…As the ageing population continues to rise, the strain on welfare resources both, human and financial, intensifies. The adoption of WT holds promise for enhancing the well-being of older persons, their significant others, organisations and caregiving staff. …”
Get full text

Fibroblast Growth Factor 21 Deficiency Attenuates Experimental Colitis-Induced Adipose Tissue Lipolysis by Liming Liu, Cuiqing Zhao, Ying Yang, Xiaoxia Kong, Tuo Shao, Li Ren, Xinyu Zhuang, Baishuang Yin, Gerald Dryden, Craig McClain, Weimin Luan, Wenke Feng

“…In addition, 3T3-L1 cells were pretreated with IL-6, followed by recombinant human FGF21 (rhFGF21) treatment; lipolysis was assessed. …”
Get full text

Emerging Risk to Dengue in Asian Metropolitan Areas Under Global Warming by Cheng Jing, Guojie Wang, Kristie L. Ebi, Buda Su, Xiaoming Wang, Dong Chen, Tong Jiang, Zbigniew W. Kundzewicz

“…Changing weather patterns can also increase the numbers of Aedes mosquitoes, leading to greater human exposure and enhancing population health risks. …”
Get full text

Huntington’s disease modeling on HEK293 cell line by D. V. Sharipova, T. B. Malankhanova, A. A. Malakhova

“…Therefore, one of the important tasks is generation of an in vitro model system of Huntington’s disease based on human cell cultures. The new genome editing approaches, such as CRISPR/Cas9, allow us to generate isogenic cell lines that can be useful for drug screening and studying mechanisms of molecular and cellular events triggered by certain mutation on an equal genetic background. …”
Get full text

RIPK1 expression and inhibition in tauopathies: implications for neuroinflammation and neuroprotection by Ignacio Silva-Llanes, Ignacio Silva-Llanes, Ignacio Silva-Llanes, Enrique Madruga, Enrique Madruga, Ana Martínez, Ana Martínez, Isabel Lastres-Becker, Isabel Lastres-Becker, Isabel Lastres-Becker, Isabel Lastres-Becker

“…Our findings show elevated levels of RIPK1 mRNA levels across various forms of tauopathies, in both mouse models and human tissue samples associated with primary and secondary TAU-related disorders. …”
Get full text

Improving Sleep Disorder Diagnosis Through Optimized Machine Learning Approaches by Md. Atiqur Rahman, Israt Jahan, Maheen Islam, Taskeed Jabid, Md Sawkat Ali, Mohammad Rifat Ahmmad Rashid, Mohammad Manzurul Islam, Md. Hasanul Ferdaus, Md Mostofa Kamal Rasel, Mahmuda Rawnak Jahan, Shayla Sharmin, Tanzina Afroz Rimi, Atia Sanjida Talukder, Md. Mafiul Hasan Matin, M. Ameer Ali

“…Classifying sleep disorders, such as obstructive sleep apnea and insomnia, is crucial for improving human quality of life due to their significant impact on health. …”
Get full text

RUBY® – a tetravalent (2+2) bispecific antibody format with excellent functionality and IgG-like stability, pharmacology and developability properties by Barnabas Nyesiga, Mattias Levin, Anna Säll, Anna Rosén, Kim Jansson, Sara Fritzell, Karin Hägerbrand, Dietmar Weilguny, Laura von Schantz

“…Also, retained interaction with FcRn is demonstrated to translate into a pharmacokinetic profile in mice and non-human primates that is comparable to mAb controls. …”
Get full text

Impact of Climate Change on the Growth of Typical Crops in Karst Areas: A Case Study of Guizhou Province by Jun Ma, Baisha Weng, Wuxia Bi, Dan Xu, Ting Xu, Dengming Yan

“…The global rising temperature is supposed to alter climatic patterns like floods and droughts, thereby affecting human life supporting system and global food production. …”
Get full text

Larval Cytotoxic and Subacute Toxicity of Gardenia ternifolia, Rourea coccinea, and Cassytha filiformis Used in Traditional Medicine of Benin (West Africa) by E. Agbodjento, J. R. Klotoé, T. I. Sacramento, T. V. Dougnon, E. Déguenon, J. Agbankpé, K. Fabiyi, P. Assogba, M.-P. Hounkanrin, R. Akotegnon, T. J. Dougnon, J.-M. Atègbo

“…However, this unregulated or irrational use may pose a risk of toxicity to humans in the short and/or long term. Recent studies reported interesting ethnopharmacological, antioxidant, and phytochemical data on some medicinal plants used in the traditional treatment of male infertility in Benin. …”
Get full text

Effectiveness of three biomimetic remineralization procedures in artificial caries-affected dentin – an in-vitro pilot study by Rosário Costa, Sofia Arantes-Oliveira, Lisete Fernandes, Fábio G. Figueiras, João Cardoso Ferreira, Paulo Ribeiro de Melo

“…Methods: Seventy-two specimens of healthy human dentin were divided into twelve groups. Half of each group’s samples were analyzed using field-emission gun environmental scanning electron microscope/energy dispersive X-ray, while the other half were analyzed by X-ray diffraction and micro-Raman spectroscopy. …”
Get full text

Isolation and Characterisation of Mesenchymal Stem Cells from Rat Bone Marrow and the Endosteal Niche: A Comparative Study by Norhayati Yusop, Paul Battersby, Amr Alraies, Alastair J. Sloan, Ryan Moseley, Rachel J. Waddington

“…Such findings support further comparisons of human CB-MSCs and BM-MSCs, facilitating selection of optimal MSC populations for regenerative medicine purposes.…”
Get full text

Differentially Expressed MicroRNAs in the Development of Early Diabetic Retinopathy by Qiaoyun Gong, Jia’nan Xie, Yang Liu, Ying Li, Guanfang Su

“…Because microRNAs (miRNAs) represent effective DR therapeutic targets, we identified aberrantly expressed miRNAs associated with cellular dysfunction in early DR and detected their potential targets. We exposed human retinal endothelial cells (HRECs) and a cell line of retinal pigment epithelial (RPE) cells to high glucose (25 mmol/L, 1–7 days) to mimic DR progression and used streptozotocin-injected rats (4–8 weeks) for an in vivo diabetes model. …”
Get full text

Multimodal heterogeneous graph fusion for automated obstructive sleep apnea-hypopnea syndrome diagnosis by Haoyu Wang, Xihe Qiu, Bin Li, Xiaoyu Tan, Jingjing Huang

“…This framework constructs two types of graph representations: physical space graphs, which map the spatial layout of sensors on the human body, and process knowledge graphs which detail the physiological relationships among breathing patterns, oxygen saturation, and vital signals. …”
Get full text

Development of Collagen-Based 3D Matrix for Gastrointestinal Tract-Derived Organoid Culture by Joo Hyun Jee, Dong Hyeon Lee, Jisu Ko, Soojung Hahn, Sang Yun Jeong, Han Kyung Kim, Enoch Park, Seon Young Choi, Sukin Jeong, Joong Woon Lee, Han-Jun Cho, Min-Soo Kwon, Jongman Yoo

“…Mouse small intestine–derived organoids, stomach-derived organoids, and human colon–derived organoids were also cultured, all of which were successfully grown in the collagen-based matrix and had similar properties compared to those cultured in Matrigel. …”
Get full text