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  1. 21881

    Effects of endocrine disrupting chemicals, blood metabolome, and epigenetics on breast cancer risk: A multi-dimensional mendelian randomization study by Ningning Song, Xinquan Xi, Kuan Yang, Chongzhe Pei, Lingzhou Zhao

    Published 2025-02-01
    “…This study uses MR to investigate the effects of three types of EDCs, including bisphenols, parabens, and phthalates, on the risk of overall breast cancer and its subtypes—Luminal A, Luminal B, triple negative, human epidermal growth factor receptor 2-enriched, and estrogen receptor-positive/negative. …”
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  2. 21882

    A sterol panel for rare lipid disorders: sitosterolemia, cerebrotendinous xanthomatosis and Smith-Lemli-Opitz syndrome by Alexander Bauer Westbye, Lili L. Dizdarevic, Sandra R. Dahl, Emil Andreas Asprusten, Yngve Thomas Bliksrud, Anita Lövgren Sandblom, Ulf Diczfalusy, Per M. Thorsby, Kjetil Retterstøl

    Published 2025-01-01
    “…A simple and rapid method to extract free sterols from human serum and quantitate their concentration using isotope-dilution liquid chromatography-tandem mass spectrometry (LC-MS/MS) without derivatization was developed. …”
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  3. 21883

    Removal of Antibiotics from Real Hospital Wastewater by Cold Plasma Technique by Phuong Thi Thanh Nguyen, Hieu Trung Nguyen, Uyen Nhat Phuoc Tran, Ha Manh Bui

    Published 2021-01-01
    “…Hospital wastewater contains a complex mixture of bioactive substances and microorganisms that are deleterious to humans and aquatic animals. In this study, four antibiotics, namely, ofloxacin, ciprofloxacin, cefuroxime, and amoxicillin, respectively, from the wastewater of seven hospitals in Ho Chi Minh City, Vietnam, were monitored. …”
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  4. 21884

    Susceptibility of Sardinella lemuru to emerging marine microplastic pollution by J.D.H. Palermo, K.L. Labrador, J.D. Follante, A.B. Agmata, M.J.R. Pante, R.N. Rollon, L.T. David

    Published 2020-07-01
    “…While results from Canonical Correspondence Analysis of ingested microplastic data had no relationship with the standard lengths of the sardine and the masses of ingested food materials at varying size classes, the total number of ingested microplastics from 2014 to 2016  were directly correlated (r<sup>2</sup>=0.91, <em>p</em>=0.003) with the human population at the landing sites  along the coastline of northern Mindanao.…”
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  5. 21885

    Intratumoral <i>Fusobacterium nucleatum</i> in Pancreatic Cancer: Current and Future Perspectives by Domenica Lucia D’Antonio, Anna Zenoniani, Samia Umme, Adriano Piattelli, Maria Cristina Curia

    Published 2024-12-01
    “…<i>Fusobacterium nucleatum (Fn)</i>, an anaerobic Gram-negative bacterium primarily residing in the oral cavity, has garnered significant attention for its emerging role in several extra-oral human diseases and, lately, in pancreatic cancer progression and prognosis. …”
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  6. 21886

    Modeling of magnetic vestibular stimulation experienced during high-field clinical MRI by Ismael Arán-Tapia, Vicente Pérez-Muñuzuri, Alberto P. Muñuzuri, Andrés Soto-Varela, Jorge Otero-Millan, Dale C. Roberts, Bryan K. Ward

    Published 2025-01-01
    “…Using high-resolution micro-CT data of the human membranous labyrinth, we ensured anatomical accuracy. …”
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  7. 21887

    Effects of Breast-Conserving Surgery Combined with Sentinel Lymph Node Biopsy on Breast Cosmetic Appearance and Systemic Stress of Patients with Breast Cancer by Jing Ji, Junfeng Shi, Xia Da, Guozhu Wang, Jin Xu

    Published 2025-01-01
    “…No significant difference was observed between the two groups regarding human epidermal growth factor receptor-2 (HER-2) expression (p > 0.05). …”
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  8. 21888

    Status of seawater intrusion in Mexico: A review by Xiaoxiao Zha, Jesús Horacio Hernández Anguiano, Francisco Padilla Benítez, Arturo Cruz-Falcón, Raul Miranda-Avilés, Manuel E. Mendoza Cantú, Jorge Adrian Perera-Burgos, Xu Liao, Juan Manuel Navarro-Céspedes, Miguel Angel Acosta-Reyes, Yanmei Li

    Published 2025-02-01
    “…This synthesis of seawater intrusion highlights the role of climate change, which directly links to human-induced pressures. The findings offer insights into coastal regions worldwide grappling with similar challenges from climate change and increasing water demand.…”
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  9. 21889

    G Protein-Coupled Receptor 17 Inhibits Glucagon-like Peptide-1 Secretion via a Gi/o-Dependent Mechanism in Enteroendocrine Cells by Jason M. Conley, Alexander Jochim, Carmella Evans-Molina, Val J. Watts, Hongxia Ren

    Published 2024-12-01
    “…Here, we expressed the human GPR17 long isoform (hGPR17L) in GLUTag cells, a murine EEC line, and we used the GPR17 synthetic agonist MDL29,951 together with pharmacological probes and genetic approaches to quantitatively assess the contribution of GPR17 signaling to GLP-1 secretion. …”
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  10. 21890

    Preparation and in vitro biological evaluation of strontium doped β-tricalcium phosphate scaffolds for alveolar bone tissue regeneration by Congrui Liu, Guiyong Xiao, Zichen Wang, Mengchen Xu, Yinchuan Wang, Nan Wang, Zhenlong Sun, Xiaoyan Li, Yixin Yin

    Published 2025-01-01
    “…A range of strategies have been devised to boost the osteogenic differentiation capacity of various biomaterials. As a human trace element, strontium (Sr) plays a vital role in bone remodeling. …”
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  11. 21891

    Metabolomics and Lipidomics Reveal the Metabolic Disorders Induced by Single and Combined Exposure of Fusarium Mycotoxins in IEC-6 Cells by Xinlu Wang, Yanyang Xu, Haiqi Yu, Yushun Lu, Yongzhong Qian, Meng Wang

    Published 2025-01-01
    “…Deoxynivalenol (DON), fumonisin B<sub>1</sub> (FB<sub>1</sub>), and zearalenone (ZEN) are typical fusarium mycotoxins that occur worldwide in foodstuffs, posing significant health hazards to humans and animals. Single and combined exposure of DON, FB<sub>1</sub>, and ZEN leads to intestinal toxicity but the toxicology mechanism research is still limited. …”
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  12. 21892

    The Role of ChatGPT and AI Chatbots in Optimizing Antibiotic Therapy: A Comprehensive Narrative Review by Ninel Iacobus Antonie, Gina Gheorghe, Vlad Alexandru Ionescu, Loredana-Crista Tiucă, Camelia Cristina Diaconu

    Published 2025-01-01
    “…However, challenges such as inconsistent handling of clinical nuances, susceptibility to unsafe advice, algorithmic biases, data privacy concerns, and limited clinical validation underscore the importance of human oversight and refinement. <b>Conclusions:</b> AI chatbots have the potential to complement antibiotic stewardship efforts by promoting appropriate antibiotic use and improving patient outcomes. …”
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  13. 21893

    Prognostic significance of mast cell and microvascular densities in malignant peripheral nerve sheath tumor with and without neurofibromatosis type 1 by Roberto André Torres de Vasconcelos, Pedro Guimarães Coscarelli, Thyago Marsicano Vieira, Washington Silva Noguera, Davy Carlos Mendes Rapozo, Marcus André Acioly

    Published 2019-03-01
    “…Recently, the essential role of mast cells in the tumor onset of neurofibromatosis type 1 (NF1)‐associated neurofibromas and MPNSTs was confirmed in both experimental and human studies. In this study, we investigate mast cell density (MCD), microvascular density (MVD), and proliferation index (Ki‐67) in MPNST. …”
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  14. 21894

    AIM2 Mediates Inflammation-Associated Renal Damage in Hepatitis B Virus-Associated Glomerulonephritis by Regulating Caspase-1, IL-1β, and IL-18 by Junhui Zhen, Le Zhang, Jiachao Pan, Shumin Ma, Xiaojian Yu, Xiaobo Li, Shijun Chen, Wenjun Du

    Published 2014-01-01
    “…Following siRNA-mediated knockdown of AIM2 in HBV-infected and HBV-uninfected human glomerular mesangial (HGM) cells, expression of caspase-1, IL-1β, and IL-18 was detected by qRT-PCR and Western blot. …”
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  15. 21895

    Epigenetic age acceleration and methylation differences in IgG4-related cholangitis and primary sclerosing cholangitis by Alexandra Noble, Rodrigo Motta, Silvia Cabras, Belen Moron Flores, Jan Nowak, Aleksandra Glapa-Nowak, Alessandra Geremia, Jack Satsangi, Emma Culver

    Published 2025-01-01
    “…Epigenetic age acceleration was observed in patients with IgG4-SC, but not in those with PSC or UC. meQTL analyses to identify genetic determinants of methylation revealed a strong human leucocyte antigen (HLA) signal in both PSC and IgG4-SC (HLA-DQB2, HLA-DPA1, HLA-F and HLA-DRA). …”
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  16. 21896

    Intensification of Natural Disasters in the State of Pará and the Triggering Mechanisms Across the Eastern Amazon by Everaldo B. de Souza, Douglas B. S. Ferreira, Luciano J. S. Anjos, Alan C. Cunha, João Athaydes Silva, Eliane C. Coutinho, Adriano M. L. Sousa, Paulo J. O. P. Souza, Waleria P. Monteiro Correa, Thaiane S. Silva Dias, Alexandre M. C. do Carmo, Carlos B. B. Gutierrez, Giordani R. C. Sodré, Aline M. M. Lima, Edson J. P. Rocha, Bergson C. Moraes, Luciano P. Pezzi, Tercio Ambrizzi

    Published 2024-12-01
    “…The detailed characterization of disasters on a municipal scale is relevant in terms of the scientific contribution applied to the strategic decision-making, planning, and implementation of public policies aimed at early risk management (rather than post-disaster response), which is critical for safeguarding human well-being and strengthening the resilience of Amazonian communities vulnerable to climate change.…”
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  17. 21897

    EEG-based functional and effective connectivity patterns during emotional episodes using graph theoretical analysis by Majid Roshanaei, Hamzeh Norouzi, Julie Onton, Scott Makeig, Alireza Mohammadi

    Published 2025-01-01
    “…These findings enhance our understanding of emotional processing and have practical applications in mental health, biomarker identification, and human-computer interaction.…”
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  18. 21898

    Lipidomics-based association study reveals genomic signatures of anti-cancer qualities of pigmented rice sprouts by Rhowell Navarro Tiozon, Rhowell Navarro Tiozon, Erstelle Pasion-Uy, Saleh Alseekh, Saleh Alseekh, Kristel June D. Sartagoda, Shem Gempesaw, Joel H. G. Tolentino, Alisdair R. Fernie, Alisdair R. Fernie, Nese Sreenivasulu

    Published 2025-01-01
    “…This study offers valuable insights into the health-promoting potential of germinated rice sprouts as a rich dietary source of antioxidants beneficial to human health.…”
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  19. 21899

    Use of digital data from open sources during the investigation of criminal offenses: certain aspects by Basysta I., Havrylyuk L., Hutnyk A., Khytra A.

    Published 2024-06-01
    “…An analysis of national legislation, national judicial practice, the Berkeley protocol for conducting an investigation using open digital data (hereinafter referred to as the Berkeley Protocol), the practice of the European Court of Human Rights, the International Criminal Court and scientific research, based on which, by means of a synthesis, the basis of the problem was identified. …”
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  20. 21900

    Science-based communication and education needed to improve forest carbon science, policy, and management outcomes by Chad C Papa, Kylie Clay, Lauren T Cooper, Scott C Stark

    Published 2025-01-01
    “…Climate change is one of the most pressing issues facing humanity and forests are increasingly seen as a key pathway to mitigating and adapting to the climate crisis. …”
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