Rare variant associations with birth weight identify genes involved in adipose tissue regulation, placental function and insulin-like growth factor signalling by Katherine A. Kentistou, Brandon E. M. Lim, Lena R. Kaisinger, Valgerdur Steinthorsdottir, Luke N. Sharp, Kashyap A. Patel, Vinicius Tragante, Gareth Hawkes, Eugene J. Gardner, Thorhildur Olafsdottir, Andrew R. Wood, Yajie Zhao, Gudmar Thorleifsson, Felix R. Day, Susan E. Ozanne, Andrew T. Hattersley, Stephen O’Rahilly, Kari Stefansson, Ken K. Ong, Robin N. Beaumont, John R. B. Perry, Rachel M. Freathy

“…Abstract Investigating the genetic factors influencing human birth weight may lead to biological insights into fetal growth and long-term health. …”
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Microenvironment Influence of a Novel Bioengineered Wound Product, APIS®: A Preliminary In Vitro Analysis of Inflammatory Marker and Growth Factor Secretion by Isaac Rodriguez, Tricia Conti, Nina Bionda

“…The biological activity the bioengineered wound product (BWP) elicits on human cells in vitro was assessed by evaluating matrix metalloproteinase- (MMP-) related proteins expressed by macrophages and secretion of growth factors in fibroblasts. …”
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Comparative analysis of Proximate and Anti-fungal Activities on Palm Oil Treated Ash Extracts of Musa sapientum and Musa paradisiaca Peels collected from Local Market in Akwa Ibom... by I. D. Uffia, O. E. Udofia, M. E. Bassey, R. O. Esen, E. J. Egong, O. D. Akan

“… Extracts from banana and plantain parts (flowers, bracts, ripe, unripe fruits, leaves, and stems) have bioactive constituents used as therapies for different human ailments. Although similar in growing on large herbs, elongated leaves, and producing edible fruits, they differ in taste and need for processing. …”
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Functional Change in the Caudal Pontine Reticular Nucleus Induced by Age-Related Hearing Loss by Ning Zhao, Ana’am Alkharabsheh, Fei Xu, Wei Sun

“…Increased acoustic startle responses (ASR), which represent reduced uncomfortable loudness level in humans, have been reported in middle-aged C57BL/6J mice with sensorineural hearing loss. …”
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Research on Density Peak Clustering Color-Separation Algorithm Based on SOM Neural Network by Xin Ru, Yanhao Wang, Ran Chen, Zhifa Zeng, Laihu Peng, Wei Tang, Weimin Shi, Hui Wang

“…To solve these problems, In this paper, we propose a density peak clustering color-separation algorithm based on self-organizing mapping (SOM) neural network, which firstly uses enhanced super-resolution generative adversarial network (Real-ESRGAN) blind super-resolution reconstruction network to clarify the degraded image and obtain a high-resolution image with clear boundaries; secondly, we carry out the initial clustering through the SOM neural network to simplify the image information; and then we use an improved density peak clustering (DPC) algorithm to calculate clustering centers under the conditions of conforming to the perception of human eyes, and carry out secondary clustering on the image; finally, carry out image post-processing through the variegated spots merging algorithm based on the connected component analysis. …”
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PPARα Activation Protects against Anti-Thy1 Nephritis by Suppressing Glomerular NF-κB Signaling by Koji Hashimoto, Yuji Kamijo, Takero Nakajima, Makoto Harada, Makoto Higuchi, Takashi Ehara, Hidekazu Shigematsu, Toshifumi Aoyama

“…To investigate whether PPARα activation improves the disease activity of MsPGN, we examined the protective effects of a PPARα agonist, clofibrate, in a well-established model of human MsPGN, anti-Thy1 nephritis, for the first time. …”
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Sentiment Analysis from Face Expressions Based on Image Processing Using Deep Learning Methods by Orhan Emre Aksoy, Selda Güney

“…In this study, the classification study of human facial expressions in real-time images is discussed. …”
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AM966, an Antagonist of Lysophosphatidic Acid Receptor 1, Increases Lung Microvascular Endothelial Permeability through Activation of Rho Signaling Pathway and Phosphorylation of V... by Junting Cai, Jianxin Wei, Shuang Li, Tomeka Suber, Jing Zhao

“…An electric cell-substrate sensing (ECIS) system was used to measure permeability in human lung microvascular endothelial cells (HLMVECs). …”
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The Effects of Microseconds Electroporation on Pore Size, Viability and Mitochondrial Membrane Potential of Cervical Cancer Cells by Güney GÜRSOY, Meriç Arda ESMEKAYA, Zehra ÇİÇEK

“…Therefore, we sought clarification regarding the phenomenon of pore formation on the membrane of the electroporated human cervical cancer cell line (HeLa) cells. Methods: The pores created on the cell membrane due to EP was observed using a scanning electron microscope. …”
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Genetic coupling of enhancer activity and connectivity in gene expression control by Helen Ray-Jones, Chak Kei Sung, Lai Ting Chan, Alexander Haglund, Pavel Artemov, Monica Della Rosa, Luminita Ruje, Frances Burden, Roman Kreuzhuber, Anna Litovskikh, Eline Weyenbergh, Zoï Brusselaers, Vanessa Xue Hui Tan, Mattia Frontini, Chris Wallace, Valeriya Malysheva, Leonardo Bottolo, Elena Vigorito, Mikhail Spivakov

“…Jointly, our findings suggest an inherent genetic coupling of enhancer activity and connectivity in gene expression control relevant to human disease and highlight the regulatory role of genetically determined chromatin boundaries.…”
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Estimation of soil erosion and risk assessment in Somalia by Abdiaziz Hassan Nur, Abdullahi Ali Ibrahim, Abas Abdi Warsame, Abdikarim Hurre Farah

“…The findings show that many regions in Somalia are highly susceptible to erosion, particularly where unsustainable human activities such as overgrazing, deforestation, and improper farming methods are prevalent. …”
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Implementasi kebijakan pelayanan angkutan laut perintis di pelabuhan kelas II teluk palu propinsi Sulawesi Tengah by Fahrudin Fahrudin, Syahruddin Hattab, Sitti Chaeriah Ahsan

“…The results of the research showed that: (1) communication to socialize the maritime transportation services of pioneer ships in hammer bay ports is still not maximized; (2) resources in terms of human resources and means are optimum, but budget (financial) and Prasarana resources are not sufficient; (3) dispositions on implementation are well running in connection with the appointment of the Commitment Maker Office (PPK) including incentives; (4) bureaucratic structures are still ineffective in relation to the mechanisms of implementation of the marine transportation service of the pioneers that have not been followed up by creating a Standard Operation Procedures (SOPs) and on the execution of the established shipping route is not appropriate and the time of sail in 1 (one) voyage is too long. …”
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Structural studies of the IFNλ4 receptor complex using cryoEM enabled by protein engineering by William S. Grubbe, Bixia Zhang, Aileen Kauffman, Fabian Byléhn, Kasia Padoł, Hae-Gwang Jung, Seung Bum Park, Jessica M. Priest, Engin Özkan, Juan J. de Pablo, T. Jake Liang, Minglei Zhao, Juan L. Mendoza

“…Abstract IFNλ4 has posed a conundrum in human immunology since its discovery in 2013, with its expression linked to complications with viral clearance. …”
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Pronerve Growth Factor Induces Angiogenesis via Activation of TrkA: Possible Role in Proliferative Diabetic Retinopathy by Sally L. Elshaer, Mohammed A. Abdelsaid, Ahmad Al-Azayzih, Parag Kumar, Suraporn Matragoon, Julian J. Nussbaum, Azza B. El-Remessy

“…The angiogenic response of aqueous humor samples from PDR patients was examined in human retinal endothelial cells in the presence or absence of anti-proNGF antibody. …”
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Karakteristik Karsinoma Serviks di RS. Dr. M. Djamil Padang Periode Januari 2010 – Desember 2013 by Panji Hadi Permana, Pelsi Sulaini, Noza Hilbertina

“…Peningkatan kasus karsinoma serviks dari tahun ke tahun disebabkan oleh berbagai faktor tetapi lebih dari 90% kasus karsinoma serviks disebabkan oleh Human Papillomavirus (HPV) onkogenik tipe 16 dan 18. …”
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Comparative Analysis of Different Drying Methods on Strawberry Aroma Compounds via Multi-Criteria Decision-Making Techniques by Nurten Cengiz, Aslı Abdulvahitoğlu, Adnan Abdulvahitoğlu

“…Food and food safety, as one of the basic issues of human life, has made it necessary to store foods for a long time with the increasing population. …”
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Hypoxia Associated Proteolytic Processing of OS-9 by the Metalloproteinase Meprin β by Barry Lee Martin, Sabena Michelle Conley, Regine Simone Harris, Corshe Devon Stanley, Jean-Marie Vianney Niyitegeka, Elimelda Moige Ongeri

“…To determine if OS-9 is a meprin substrate, kidney proteins from meprin αβ knockout mice (αβKO) (which lack endogenous meprins) and purified human OS-9 were incubated with activated forms of meprin A and meprin B, and Western blot analysis was used to evaluate proteolytic processing of OS-9. …”
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Queue Formation and Obstacle Avoidance Navigation Strategy for Multi-Robot Systems Based on Deep Reinforcement Learning by Tianyi Gao, Zhanlan Li, Zhixin Xiong, Ling Wen, Kai Tian, Kewei Cai

“…In contemporary society, the widespread application of robotics across various domains emphasizes the critical role of robotic systems in performing tasks that are too dangerous or complex for humans. However, individual robots often struggle with these intricate tasks, necessitating the collaboration of multi-robot systems. …”
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The impact of obstetric violence on postpartum quality of life through psychological pathways by Shahnaz Kohan, Desirée Mena-Tudela, Samaneh Youseflu

“…Abstract Pregnancy and childbirth as important events in women’s lives should be guided based on quality and humanized principles. This study aimed to test a conceptual model considering the interrelated role of obstetric violence, mental health, self-esteem, and PTSD on the postpartum quality of life (PQOL) using path analysis. …”
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An Aptamer Sensor Based on Alendronic Acid-Modified Upconversion Nanoparticles Combined with Magnetic Separation for Rapid and Sensitive Detection of Thiamethoxam by Qian Huang, Lu Han, Hui Ma, Weijie Lan, Kang Tu, Jing Peng, Jing Su, Leiqing Pan

“…The widespread use of thiamethoxam has led to pesticide residues that have sparked global concerns regarding ecological and human health risks. A pressing requirement exists for a detection method that is both swift and sensitive. …”
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