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Synaptic transistor implementing potentiation or depression via field distribution modulation of dual dielectric layers by single-polarity pulsed voltage stimuli
Published 2025-03-01“…Understanding and simulating the synaptic plasticity mechanisms of the human brain are crucial for advancing neuromorphic computers for artificial intelligence (AI) and humanoid applications. …”
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222
CD2AP deficiency aggravates Alzheimer’s disease phenotypes and pathology through p38 MAPK activation
Published 2024-12-01Get full text
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223
Analysis of argument structure constructions in the large language model BERT
Published 2025-01-01“…This research demonstrates the potential of both recurrent and transformer-based neural language models to mirror linguistic processing in the human brain, offering valuable insights into the computational and neural mechanisms underlying language understanding.…”
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224
Deep-learning-based extraction of circle of Willis topology with anatomical priors
Published 2024-12-01“…Abstract The circle of Willis (CoW) is a circular arrangement of arteries in the human brain, exhibiting significant anatomical variability. …”
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Left-Right Brain-Wide Asymmetry of Neuroanatomy in the Mouse Brain
Published 2025-02-01“…Left-right asymmetry of the human brain is widespread through its anatomy and function. …”
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227
Transformers for Neuroimage Segmentation: Scoping Review
Published 2025-01-01“…The inclusion criteria allow only for peer-reviewed journal papers and conference papers focused on transformer-based segmentation of human brain imaging data. Excluded are the studies dealing with nonneuroimaging data or raw brain signals and electroencephalogram data. …”
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228
Glaucoma progression during the COVID-19 pandemics
Published 2021-09-01“…Bekhtereva Institute of the Human Brain, St. Petersburg, Russian Federation</b> </p> <p> <b><sup>3</sup>P.V. …”
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229
NORDIC denoising on VASO data
Published 2025-01-01“…The use of submillimeter resolution functional magnetic resonance imaging (fMRI) is increasing in popularity due to the prospect of studying human brain activation non-invasively at the scale of cortical layers and columns. …”
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230
DeepCERES: A deep learning method for cerebellar lobule segmentation using ultra-high resolution multimodal MRI
Published 2025-03-01“…This paper introduces a novel multimodal and high-resolution human brain cerebellum lobule segmentation method. Unlike current tools that operate at standard resolution (1 mm3) or using mono-modal data, the proposed method improves cerebellum lobule segmentation through the use of a multimodal and ultra-high resolution (0.125 mm3) training dataset. …”
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231
Bullatine A suppresses glioma cell growth by targeting SIRT6
Published 2025-01-01“…In this study, we investigated the effects of BLA on human brain malignant glioblastoma cells. Our results showed that BLA inhibited the proliferation of U87MG and U251 cells in a dose-dependent manner and decreased their survival rate. …”
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232
Age-associated microglial transcriptome leads to diminished immunogenicity and dysregulation of MCT4 and P2RY12/P2RY13 related functions
Published 2025-01-01“…Remarkably, protein analysis in human brain tissue validated the observed upregulation of MCT4 and downregulation of P2RY12 in aged microglia. …”
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233
Plasma S100β is a predictor for pathology and cognitive decline in Alzheimer’s disease
Published 2025-01-01“…Brain slices were then imaged using confocal microscopy and analyzed for microvascular diameters and immunoreactivity coverage using Fiji/ImageJ. Isolated human brain microvessels were assayed for tight-junction protein expression using the JESS™ automated Western blot system. …”
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234
Repetitive antigen stimulation in the periphery dictates the composition and recall responses of brain-resident memory CD8+ T cells
Published 2025-02-01“…Summary: The human brain harbors virus-specific, tissue-resident memory (TRM) CD8+ T cells. …”
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235
The Genetic Landscape of Human Glioblastoma and Matched Primary Cancer Stem Cells Reveals Intratumour Similarity and Intertumour Heterogeneity
Published 2019-01-01“…Glioblastoma (GBM) is the most malignant human brain tumour, characterized by rapid progression, invasion, intense angiogenesis, high genomic instability, and resistance to therapies. …”
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236
Maternal phthalates exposure promotes neural stem cell differentiation into phagocytic astrocytes and synapse engulfment via IRE1α/XBP1s pathway
Published 2025-01-01“…This phenotype is further recapitulated in a human brain organoid model. Together, these findings unveil the molecular mechanism underlying the neurodevelopmental deficits caused by a widespread environmental pollutant.…”
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State-of-the-art of loading and unloading tests for glaucoma: potentialities and informative value
Published 2021-09-01“…Bekhtereva Institute of the Human Brain, St. Petersburg, Russian Federation</b> </p> <p> <i>Prevention of blindness and low vision resulting fr om the progression of glaucomatous optic neuropathy (GON) depends mainly on the early diagnosis of glaucoma. …”
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239
Brimonidine as an additional treatment for moderate glaucoma
Published 2021-05-01“…Bekhtereva Institute of the Human Brain, Saint Petersburg, Russian Federation</b> </p> <p> <b><sup>2</sup>LLC “American Medical Clinic”, Saint Petersburg, Russian Federation</b> </p> <p> <b><sup>3</sup>I.I. …”
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240
From non-human to human primates: a translational approach to enhancing resection, safety, and indications in glioma surgery while preserving sensorimotor abilities
Published 2025-02-01“…By using data acquired on non-human primates as a reference, important progress in knowledge of the human brain and its functions has been achieved. The translational impact allowed by this scientific effort must be recognized in the implementation of the current surgical techniques particularly in support of the neurosurgical approach to brain tumors. …”
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