Genomics Analysis of Metabolic Pathways of Human Stem Cell-Derived Microglia-Like Cells and the Integrated Cortical Spheroids by Julie Bejoy, Xuegang Yuan, Liqing Song, Thien Hua, Richard Jeske, Sébastien Sart, Qing-Xiang Amy Sang, Yan Li

“…Brain spheroids or organoids derived from human pluripotent stem cells (hiPSCs) are still not capable of completely recapitulating in vivo human brain tissue, and one of the limitations is lack of microglia. …”
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Multitask Learning-Based Pipeline-Parallel Computation Offloading Architecture for Deep Face Analysis by Faris S. Alghareb, Balqees Talal Hasan

“…Deep Neural Networks (DNNs) have been widely adopted in several advanced artificial intelligence applications due to their competitive accuracy to the human brain. Nevertheless, the superior accuracy of a DNN is achieved at the expense of intensive computations and storage complexity, requiring custom expandable hardware, i.e., graphics processing units (GPUs). …”
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Development and in vitro evaluation of biomimetic injectable hydrogels from decellularized human nerves for central nervous system regeneration by Gopal Agarwal, Kennedy Moes, Christine E. Schmidt

“…Human SH-SY5Y neuroblastoma cells exhibited higher viability and improved neuronal differentiation in iHPN compared to TCP. Human brain neurons had higher neuronal differentiation within iHPN compared to TCP or collagen hydrogels. …”
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Brief exposure to (-) THC affects zebrafish embryonic locomotion with effects that persist into the next generation by Md Ruhul Amin, Lakhan Khara, Joshua Szaszkiewicz, Andrew M. Kim, Trevor J. Hamilton, Declan W. Ali

“…Abstract Cannabis is one of the most widely used drugs, and yet an understanding of its impact on the human brain and body is inconclusive. Medicinal and recreational use of cannabis has increased in the last decade with a concomitant increase in use by pregnant women. …”
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Key regions aberrantly connected within cerebello-thalamo-cortical circuit and their genetic mechanism in schizophrenia: an fMRI meta-analysis and transcriptome study by Yarui Wei, Ziyu Wang, Kangkang Xue, Xiaoyu Niu, Longyao Ma, Shaoqiang Han, Baohong Wen, Yong Zhang, Huafu Chen, Jingliang Cheng

“…Gene annotation analysis was performed to identify genes over-expressed in these regions by using the Allen Human Brain Atlas, followed by a set of gene functional feature analyses. 19 studies (1333 patients and 1174 healthy controls) were included in this meta-analysis. …”
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Protocols for the application of human embryonic stem cell-derived neurons for aging modeling and gene manipulation by Hui Zhang, Shuhui Sun, Juan Carlos Izpisua Belmonte, Guang-Hui Liu, Si Wang, Weiqi Zhang, Jing Qu

“…Summary: In vitro models of neuronal aging and gene manipulation in human neurons (hNeurons) are valuable tools for investigating human brain aging and diseases. Here, we present a protocol for applying human embryonic stem cell (hESC)-derived neurons to model aging and the further application of small interfering RNA (siRNA)-mediated gene silencing for functional investigations. …”
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Book phenomenon in library philosophy and library research by Baiba Sporane

“…The book is the mirror of those who look into it (and who create this mirror too), and its idea can be found in the human brain. Therefore, the book is very closely connected with humans and society as a tool of human inter-subjective action. …”
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Structure and dynamics analysis of brain functional hypernetworks based on the null models by Chen Cheng, Yao Li, Chunyan Wang, Yanli Yang, Hao Guo

“…Such studies can help to explore how the important functional features of brain functional hypernetworks characterize the working and pathological mechanisms of the human brain. Therefore, this article introduces the hypernetwork null model to analyze the dependencies between the features of interest. …”
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Quality of Life Philosophy IV. The Brain and Consciousness by Søren Ventegodt, Niels Jørgen Andersen, Joav Merrick

“…The connectivity seems to imply that the patterns of the human brain are 1000-dimensional. It is our vision that these complicated patterns arise from basic patterns in the quantum matter of which everything is created. …”
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Functional connectome gradient of prefrontal cortex as biomarkers of high risk for internet gaming disorder by Xinwen Wen, Lirong Yue, Zhe Du, Jiahao Zhao, Mengjiao Ge, Cunfeng Yuan, Hongmei Wang, Qinghua He, Kai Yuan

“…We used functional connectome gradient (FCG) to capture the macroscopic hierarchical organization of human brain. Canonical correlation analysis was employed to identify components mapping relationships between FCG and behavioral scores. …”
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Distinct neural computations scale the violation of expected reward and emotion in social transgressions by Ting Xu, Lei Zhang, Feng Zhou, Kun Fu, Xianyang Gan, Zhiyi Chen, Ran Zhang, Chunmei Lan, Lan Wang, Keith M. Kendrick, Dezhong Yao, Benjamin Becker

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Assessment of maternal health and behavior during pregnancy in the HEALthy Brain and Child Development Study: Rationale and approach by Kelly K. Gurka, Heather H. Burris, Lucia Ciciolla, Claire D. Coles, Suena H. Massey, Sharlene Newman, Vidya Rajagopalan, Lynne M. Smith, Anna Zilverstand, Gretchen Bandoli

“…The Healthy Brain and Child Development (HBCD) Study, a multi-site, prospective, longitudinal cohort study, will examine human brain, cognitive, behavioral, social, and emotional development beginning prenatally and planned through early childhood. …”
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A novel pulse-current waveform circuit for low-energy consumption and low-noise transcranial magnetic stimulation by Xinhua Tan, Ao Guo, Jiasheng Tian, Yingwei Li, Yingwei Li, Jian Shi

“…IntroductionTranscranial magnetic stimulation (TMS) is widely used for the noninvasive activation of neurons in the human brain. It utilizes a pulsed magnetic field to induce electric pulses that act on the central nervous system, altering the membrane potential of nerve cells in the cerebral cortex to treat certain mental diseases. …”
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Brain network alterations in anorexia Nervosa: A Multi-Center structural connectivity study by Jun Kanzawa, Ryo Kurokawa, Tsunehiko Takamura, Nobuhiro Nohara, Kouhei Kamiya, Yoshiya Moriguchi, Yasuhiro Sato, Yumi Hamamoto, Tomotaka Shoji, Tomohiko Muratsubaki, Motoaki Sugiura, Shin Fukudo, Yoshiyuki Hirano, Yusuke Sudo, Rio Kamashita, Sayo Hamatani, Noriko Numata, Koji Matsumoto, Eiji Shimizu, Naoki Kodama, Shingo Kakeda, Masatoshi Takahashi, Satoru Ide, Kazumasa Okada, Shu Takakura, Motoharu Gondo, Kazufumi Yoshihara, Masanori Isobe, Keima Tose, Tomomi Noda, Ryo Mishima, Michiko Kawabata, Shun’ichi Noma, Toshiya Murai, Kazuhiro Yoshiuchi, Atsushi Sekiguchi, Osamu Abe

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Effective Facial Expression Recognition System Using Artificial Intelligence Technique by Imad S. Yousif, Tarik A. Rashid, Ahmed S. Shamsaldin, Sabat A. Abdulhameed, Abdulhady Abas Abdullah

“…ANNS are inspired by the neural architecture of human brain capable of learning and recognizing patterns in unchartered data after trained examples, on the other hand GAs come from fundamental principles underlying natural selection perform optimization process based-on evolutionary methods which includes fitness evaluation, comparison, selection, crossover, and mutation. …”
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Role of neuroinflammation in the pathogenesis of glaucomatous optic neuropathy by E.A. Egorov, V.E. Korelina, D.V. Cherednichenko, I.R. Gazizova

“…Bekhtereva Institute of the Human Brain, St. Petersburg, Russian Federation</b> </p> <p> <i>This article reviews recent studies on the etiology and pathogenesis of primary open-angle glaucoma (POAG). …”
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Endothelial-Ercc1 DNA repair deficiency provokes blood-brain barrier dysfunction by Cathrin E. Hansen, Davide Vacondio, Lennart van der Molen, Annika A. Jüttner, Wing Ka Fung, Manon Karsten, Bert van het Hof, Ruud D. Fontijn, Gijs Kooij, Maarten E. Witte, Anton J. M. Roks, Helga E. de Vries, Inge Mulder, Nienke M. de Wit

“…We here investigated how endothelial aging impacts blood-brain barrier (BBB) function by using excision repair cross complementation group 1 (ERCC1)-deficient human brain ECs and an EC-specific Ercc1 knock out (EC-KO) mouse model. …”
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Lack of intracranial atherosclerosis in various atherosclerotic mouse models by Diewertje I Bink, Katja Ritz, Claire Mackaaij, Olga Stam, Sanny Scheffer, Mark R Mizee, Hanneke J Ploegmakers, Bert J van het Hof, Onno J de Boer, Judith C Sluimer, Guido R Y De Meyer, Louise van der Weerd, Helga E de Vries, Mat J A P Daemen

“…Higher HO-1 expression was also shown in human intracranial arteries. Human brain endothelial cell stimulation with oxidized LDL induced endogenous protective antioxidant HO-1 levels through NRF2 translocation. …”
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Genetic and neurochemical profiles underlying cortical morphometric vulnerability to Parkinson’s disease by Su Yan, Jun Lu, Bingfang Duan, Hongquan Zhu, Tian Tian, Yuanyuan Qin, Yuanhao Li, Wenzhen Zhu

“…Then we performed gene-category enrichment and spatial correlation analyses to evaluate the specific correspondence between cortical alteration in PD and genetic expression from the Allen Human Brain Atlas and normative neurotransmitter atlases from Neuromaps. …”
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Mind wandering enhances statistical learning by Teodóra Vékony, Bence C. Farkas, Bianka Brezóczki, Matthias Mittner, Gábor Csifcsák, Péter Simor, Dezső Németh

“…Summary: The human brain spends 30–50% of its waking hours engaged in mind-wandering (MW), a common phenomenon in which individuals either spontaneously or deliberately shift their attention away from external tasks to task-unrelated internal thoughts. …”
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