A Short History of the Genome-Wide Association Study: Where We Were and Where We Are Going by Shiro Ikegawa

Subjects: Get full text

I’ll Show You Mine, If You Show Me Yours

“…Both Science and Nature lead this week with articles about the simultaneous publication of the human genome sequence by the private company Celera Genomics and the publicly funded Human Genome Project (HGP).…”
Get full text

Human microbiome, applied to clinical practice by V. T. Ivashkin, K. V. Ivashkin

“…The Human Microbiome Project became the sequel of The Human Genome Project. Summary. The human microbiome represents a variety of microbial species with the differing metabolic activity. …”
Get full text

ENCODE: A Sourcebook of Epigenomes and Chromatin Language by Maryam Yavartanoo, Jung Kyoon Choi

“…Until recently, since the Human Genome Project, the general view has been that the majority of the human genome is composed of junk DNA and has little or no selective advantage to the organism. …”
Get full text

The Impact of Transposable Elements in Genome Evolution and Genetic Instability and Their Implications in Various Diseases by Selvam Ayarpadikannan, Heui-Soo Kim

“…Results from the Human Genome Project have emphasized the biological importance of TEs. …”
Get full text

Next-Generation Sequencing and Epigenomics Research: A Hammer in Search of Nails by Shrutii Sarda, Sridhar Hannenhalli

“…After the initial enthusiasm of the human genome project, it became clear that without additional data pertaining to the epigenome, i.e., how the genome is marked at specific developmental periods, in different tissues, as well as across individuals and species-the promise of the genome sequencing project in understanding biology cannot be fulfilled. …”
Get full text

Nutrigenomics: Definitions and Advances of This New Science by N. M. R. Sales, P. B. Pelegrini, M. C. Goersch

“…With the advance of science, especially after the conclusion of the Human Genome Project (HGP), scientists started questioning if the interaction between genes and food bioactive compounds could positively or negatively influence an individual’s health. …”
Get full text

Perspectives on Clinical Informatics: Integrating Large-Scale Clinical, Genomic, and Health Information for Clinical Care by In Young Choi, Tae-Min Kim, Myung Shin Kim, Seong K. Mun, Yeun-Jun Chung

“…The widespread adoption of EMR systems and the completion of the Human Genome Project developed the technologies for data acquisition, analysis, and visualization in two different domains. …”
Get full text

Genetic ancestry and the colonial legacies of race in genomics: a cross-disciplinary dialogue by Ernesto Schwartz-Marin, Tayyaba Jiwani, Sarah Abel, Yulia Egorova, Amade M’charek, Diogo Meyer, Andrés Moreno Estrada, Katharina Schramm, Peter Wade, Michel Naslavsky, Michel Naslavsky

“…This is despite the fact that geneticists broadly dismissed racial categories as obsolete and unfounded after the Human Genome Project was completed in 2003. In fact, contemporary genomics initiatives have often ended up reinforcing ethnocentric and nativist conceptions of difference, drawing intense criticism from activists and critical social scientists. …”
Get full text