Prevalence of Coronary Endothelial and Microvascular Dysfunction in Women with Symptoms of Ischemia and No Obstructive Coronary Artery Disease Is Confirmed by a New Cohort: The NHL... by R. David Anderson, John W. Petersen, Puja K. Mehta, Janet Wei, B. Delia Johnson, Eileen M. Handberg, Saibal Kar, Bruce Samuels, Babak Azarbal, Kamlesh Kothawade, Sheryl F. Kelsey, Barry Sharaf, Leslee J. Shaw, George Sopko, C. Noel Bairey Merz, Carl J. Pepine

“…In WISE (n=181) and WISE-CVD (n=235) women, mean age in both was 54 years, and 83% were white (WISE) vs 74% (WISE-CVD, p=0.04). Use of hormone replacement therapy was less frequent in WISE-CVD vs WISE (46% vs 57%, p=0.026) as was presence of hypertension (40% vs 52%, p=0.013), hyperlipidemia (20% vs 46%, p<0.0001), and smoking (46% vs 56%, p=0.036). …”
Get full text

The Rapid Effect of Bisphenol-A on Long-Term Potentiation in Hippocampus Involves Estrogen Receptors and ERK Activation by Xiaowei Chen, Yu Wang, Fang Xu, Xiaofei Wei, Junfang Zhang, Chuang Wang, Hua Wei, Shujun Xu, Peiyun Yan, Wenhua Zhou, Istvan Mody, Xiaohong Xu, Qinwen Wang

“…Bisphenol-A (BPA), a widely used synthetic compound in plastics, disrupts endocrine function and interferes with physiological actions of endogenous gonadal hormones. Chronic effects of BPA on reproductive function, learning and memory, brain structure, and social behavior have been intensively investigated. …”
Get full text

Impact of post-breeding administration of hCG and flunixin meglumine on luteal function and pregnancy rates in anestrous Nili-Ravi buffaloes by Ejaz Ahmad, Muhammad Muzammal Niaz, Muhammad Saleem Akhtar, Muhammad Rizwan Yousuf, Muhammad Zahid Tahir, Tanveer Ahmad

“… This study was conducted to determine the impact of post-breeding administration of human chorionic gonadotropin hormone (hCG) and flunixin meglumine on luteal function and pregnancy rates in postpartum anoestrous Nili-Ravi buffaloes synchronized through a CIDR-GnRH based protocol during low breeding season. …”
Get full text

Hypercalcemia Following Adrenalectomy for Cushing Syndrome in a Patient with Post-Surgical Hypoparathyroidism by Pietro Locantore, Alessandro Oliva, Gianluca Cera, Rosa Maria Paragliola, Roberto Novizio, Caterina Policola, Andrea Corsello, Alfredo Pontecorvi

“…On each occasion, parathyroid hormone levels were confirmed to be undetectable, with low vitamin D levels. …”
Get full text

Clinical and biochemical characteristics of patients with acromegaly and normal or increased prolactin levels by Yuliya A. Kukushkina, Irena A. Ilovayskaya

“…Conclusion: The results of our study emphasize the importance to exclude acromegaly in patients with prolactinomas and in those with suspected pituitary stalk compression (which is characterized by moderate hyperprolactinemia and suprasellar growth of the pituitary adenoma), even in the absence of pathognomic signs of increased secretion of growth hormone. Hyperprolactinemia does not affect the treatment outcomes in acromegaly, and more frequent administration of dopamine receptor agonists does not result in an increased proportion of patients with biochemical control of the main disease.…”
Get full text

Comparison of different GnRH compounds on fertility outcomes in ovulation synchronized and presynchronized beef cows by Nicola Oosthuizen, Lucas M. Goncalves, Samir Burato, Molly S. Smith, Kelsey M. Harvey, Graham Cliff Lamb, Graham Cliff Lamb, Pedro L. P. Fontes

“…This study evaluated the use of two different gonadotropin-releasing hormone (GnRH) compounds in estrus synchronization protocols with or without presynchronization. …”
Get full text

Machine learning models for dementia screening to classify brain amyloid positivity on positron emission tomography using blood markers and demographic characteristics: a retrospec... by Noriyuki Kimura, Kotaro Sasaki, Teruaki Masuda, Takuya Ataka, Mariko Matsumoto, Mika Kitamura, Yosuke Nakamura, Etsuro Matsubara

“…In models using blood test results, thyroid-stimulating hormone and mean corpuscular volume tended to be the largest contributors to classification. …”
Get full text

Estradiol-dependent and independent effects of FGF21 in obese female mice by T. V. Jakovleva, A. Yu. Kazantseva, A. D. Dubinina, N. Yu. Balybina, K. O. Baranov, E. N. Makarova, N. M. Bazhan

“…The f ibroblast growth factor 21 (FGF21) synthesized in the liver, acting as a hormone, increases insulin sensitivity and energy expenditure. …”
Get full text

MicroRNA Expression in Cutaneous Lupus: A New Window to Understand Its Pathogenesis by Silvia Méndez-Flores, Janette Furuzawa-Carballeda, Gabriela Hernández-Molina, Gustavo Ramírez-Martinez, Nora E. Regino-Zamarripa, Blanca Ortiz-Quintero, Luis Jiménez-Alvarez, Alfredo Cruz-Lagunas, Joaquín Zúñiga

“…The KEGG pathway enrichment analysis revealed that cell cycle regulation pathways, p53, TGF-β, thyroid hormone, and cancer signaling pathways were shared between miR-21, miR-31, miR-23b, miR-146a, miR-1246, and miR-150. …”
Get full text

Does coenzyme Q10 improve semen quality and circulating testosterone level? a systematic review and meta-analysis of randomized controlled trials by Tunmise M. Akhigbe, Tunmise M. Akhigbe, Fabrael B. Fidelis, Fabrael B. Fidelis, Adebayo O. Adekunle, Adebayo O. Adekunle, Victory J. Ashonibare, Victory J. Ashonibare, Bolaji A. Akorede, Bolaji A. Akorede, Mansur S. Shuaibu, Mansur S. Shuaibu, Suliat A. Hassan, Cecilia A. Adegbola, Cecilia A. Adegbola, Precious J. Ashonibare, Precious J. Ashonibare, Opeyemi M. Oladapo, Opeyemi M. Oladapo, Adetomiwa E. Adeogun, Adetomiwa E. Adeogun, Adetomiwa E. Adeogun, Seun G. Bamidele, Seun G. Bamidele, Precious A. Oyedokun, Precious A. Oyedokun, Mungala Mukolokota, Mungala Mukolokota, Omotolani S. Kukoyi, Omotolani S. Kukoyi, Ayoola A. Oladipo, Ayoola A. Oladipo, Olayinka E. Adelowo, Olayinka E. Adelowo, Marvelous D. Akangbe, Marvelous D. Akangbe, Jennifer R. Hughes, Albert M. Ricken, Martine Culty, Maria C. W. Avellar, Roland E. Akhigbe, Roland E. Akhigbe

“…In addition, the effects of CoQ10 supplementation on circulating testosterone, luteinizing hormone (LH), follicle-stimulating hormone (FSH), and inhibin B levels were evaluated.DesignA systematic review and a meta-analysis of randomized controlled trials (RCTs) were performed to assess the effects of CoQ10 supplementation on semen quality and serum levels of male reproductive hormones.MethodsWe conducted a strategic literature search in the Cochrane, EMBASE, PubMed/MEDLINE, Scopus, and Web of Science databases and collected only RCTs. …”
Get full text

Potential use of beet-pulp concentrate supplementation in athletic horse by Luzilene Araujo de Souza, Monica Miranda Hunka, Sigismundo Fassbender de Rezende Júnior, Carolina Jones Ferreira Lima da Silva, Helena Emília Cavalcanti da Costa Cordeiro Manso, Joana Simões, Clarisse Simões Coelho, Francesco Fazio, Francesca Aragona, Hélio Cordeiro Manso Filho

“…Blood samples were collected before and at 30, 60 and 90 days of training and results demonstrated the highest level of [NEFA] and [triglycerides] at end of experimental period (p < 0.05) and increased of growth hormone after exercise sections after 60 days (p < 0.05). …”
Get full text

Extracellular vesicles-derived miR-21 as a biomarker for early diagnosis and tumor activity in breast cancer subtypes by Claudia Omarini, Virginia Catani, Ilenia Mastrolia, Angela Toss, Federico Banchelli, Chrystel Isca, Daniele Medici, Ornella Ponzoni, Marco Brucale, Francesco Valle, Maria Cristina Baschieri, Roberto D’Amico, Valentina Masciale, Chiara Chiavelli, Federica Caggia, Carlo Augusto Bortolotti, Federico Piacentini, Massimo Dominici

“…The levels of miR-21 were higher in the MBC group than in the HD group (p = 0.029), mainly in those who were human epidermal growth factor receptor 2 (HER2)+ (p = 0.0005) and hormone receptor-positive (p = 0.036). In particular, in the HER2 + subgroup, the miR-21 levels were significantly higher in those with active BC (both EBC and MBC) than in HDs (p = 0.002). …”
Get full text

Preoperative and Postoperative Bone Mineral Density Change and Risk Factor Analysis in Patients with a GH-Secreting Pituitary Adenoma by Li’nan Qin, Xiaopeng Guo, Lu Gao, Zihao Wang, Chenzhe Feng, Kan Deng, Wei Lian, Bing Xing

“…Clinical data of 39 patients with growth hormone- (GH-) secreting pituitary adenomas and 29 patients with nonfunctioning pituitary adenomas who were newly diagnosed in neurosurgery from January 2016 to December 2018 were retrospectively analysed, including measurements of preoperative and postoperative BMD, serum GH glucose inhibition, random GH and IGF-1, and other anterior pituitary hormones. …”
Get full text

Effects of non-pharmacological interventions on biochemical hyperandrogenism in women with polycystic ovary syndrome: a systematic review and network meta-analysis by Qi Jin, Ge Xu, Yuchen Ying, Lumin Liu, Huimin Zheng, Shifen Xu, Ping Yin, Yuelai Chen

“…No significant effects were observed on Free Androgen Index (FAI), Sex Hormone-Binding Globulin (SHBG), Dehydroepiandrosterone (DHEA), DHEA Sulfate (DHEAS), Free Testosterone (FT), or Dihydrotestosterone (DHT) levels (all p > 0.05). …”
Get full text

Research progress and application status of organoid in breast cancer subtypes by Qiuxia Zhang, Min Wang, Li You, Chen Chen, Jia Feng, Miao Song, Kui Yang, Xuexue Liu, Guangrong Li, Jinbo Liu

“…The complexity of basic BC research and clinical treatment is influenced by multiple factors, including age, fertility, hormone metabolism, molecular subtypes, and tumor grading and staging. …”
Get full text

Metabolic Profiling by UPLC–Orbitrap–MS/MS of Liver from C57BL/6 Mice with DSS-Induced Inflammatory Bowel Disease by Zhongquan Xin, Zhenya Zhai, Hongrong Long, Fan Zhang, Xiaojun Ni, Jinping Deng, Lunzhao Yi, Baichuan Deng

“…Metabolism network and pathway analyses demonstrated that the metabolic disturbance of the liver in IBD mice was mainly enriched in bile acid metabolism, arachidonic acid metabolism, amino acid metabolism, and steroid hormone biosynthesis, while those disturbances were regulated or reversed through cecropin A and antibiotic treatment. …”
Get full text

Whole-genome resequencing landscape of adaptive evolution in Relict gull (Larus relictus) by Chao Yang, Qingxiong Wang, Kuo Sun, Lei Luo, Hao Yuan, Xuejuan Li, Yuan Huang, Hong Xiao

“…In addition, MED1, CNOT9, NR5A1, and PATZ1 were involved in enhanced male hormone secretion and a high density of candidate genes associated with embryonic development were identified. …”
Get full text

Hubungan Kebiasaan Merokok dengan Waist to Hip Ratio (WHR) pada Nelayan di Kecamatan Koto Tangah Kota Padang by Fathiyyatul Khaira, Delmi Sulastri, Rima Semiarty

“…<div class="WordSection1"><p><strong>Abstrak</strong></p><p>Nikotin pada rokok mempunyai efek anti estrogenik dan meningkatkan hormon kortisol yang mengakibatkan deposisi lemak ke abdomen maupun pengurangan massa otot panggul yang menyebabkan peningkatan <em>Waist to Hip</em> <em>Ratio </em>(WHR). …”
Get full text

Assessment of Body Composition, Bone Density, and Biochemical Markers of a Natural Bodybuilder During Contest Preparation by Konstantinos Michailidis, Nikolaos Zaras, Dimitrios Balampanos, Alexandra Avloniti, Theodoros Stampoulis, Maria Protopapa, Dimitrios Pantazis, Nikolaos-Orestis Retzepis, Ilias Smilios, Athanasios Chatzinikolaou

“…At the beginning (W31), in the middle (W18), and one week before the contest (W1), measurements included body composition via DEXA, testosterone and cortisol hormonal concentrations, and lipid, blood, and liver biochemical markers via an automated hematology analyzer. …”
Get full text

Genome-Wide Comprehensive Identification and In Silico Characterization of Lectin Receptor-Like Kinase Gene Family in Barley (Hordeum vulgare L.) by Fee Faysal Ahmed, Farah Sumaiya Dola, Md Shohel Ul Islam, Fatema Tuz Zohra, Nasrin Akter, Shaikh Mizanur Rahman, Md. Abdur Rauf Sarkar

“…The promoter cis-acting regulatory element (CARE) analysis of barley identified a total of 75 CARE motifs responsive to light responsiveness (LR), tissue-specific (TS), hormone responsiveness (HR), and stress responsiveness (SR). …”
Get full text