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1721
Variations in the Obesity Gene “LEPR” Contribute to Risk of Type 2 Diabetes Mellitus: Evidence from a Meta-Analysis
Published 2016-01-01“…Leptin is a hormone protein regulating food intake and energy expenditure. …”
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1722
Risk Factors of Upper Limb Lymphedema after Breast Cancer Surgery in Women
Published 2019-10-01“….), the tumor data (pathological type, stage, postoperative hormone receptor, the Her-2, number of lymph node dissection, number of positive lymph nodes, etc.) and the treatment data (surgery way, axillary lymph node processing way, whether to accept radiation therapy, whether to accept postoperative chemotherapy, chemotherapy program, chemotherapy cycles, whether to accept endocrine therapy, endocrine medication and medication time, etc.), establishing the clinical data bases of BCRL. …”
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1723
The mechanisms of melanogenesis inhibition by glabridin: molecular docking, PKA/MITF and MAPK/MITF pathways
Published 2023-01-01“…The treatment by glabridin significantly downregulated both transcriptional and/or protein expression of melanogenesis-related factors including melanocyte stimulating hormone receptor (MC1R), microphthalmia-associated transcription factor (MITF), tyrosinase (TYR), TYR-related protein-1 (TRP-1) and TRP-2 in B16 cells. …”
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1724
Molecular Mechanisms of Breast Cancer Drug Resistance and CRISPR/Cas9 Strategies to Overcome
Published 2024-12-01“…Recent research has effectively investigated and targeted particular genes linked to BC treatment resistance using CRISPR/Cas9 gene editing, including those linked to hormone receptor signaling, drug efflux transporters, and DNA repair pathways. …”
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1725
Transient sex-related changes in the mice hypothalamo–pituitary–adrenal (HPA) axis during the acute phase of the inflammatory process
Published 1993-01-01“…The potential role of endogenous sex hormones in regulating hypothalamo–pituitary–adrenal (HPA) axis function was investigated after a single injection of endotoxin in adult (8 week old) BALB/c mice of both sexes. …”
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1726
The preoperative neutrophil‐to‐lymphocyte ratio is not a marker of prostate cancer characteristics but is an independent predictor of biochemical recurrence in patients receiving r...
Published 2019-03-01“…When we analyzed the data of patients without postoperative adjuvant hormone therapy or radiotherapy, univariate and multivariate survival analysis indicated that a high NLR was a predictor of better BCR‐free survival (P < 0.05). …”
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1727
The impact of heterotopic ovarian tissue transplantation with varied volumes on reproductive endocrine function in oophorectomized rats
Published 2024-12-01“…The post-transplant oestrous cycle recovery was observed, and blood samples were collected every 2 weeks to measure serum hormone levels. Histological evaluation was performed at the end of the observation period.Results Rats in Group V exhibited disrupted oestrous cycles after transplantation, which were significantly longer than those in Group I. …”
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1728
Impact of Abdominal Obesity on Thyroid Auto-Antibody Positivity: Abdominal Obesity Can Enhance the Risk of Thyroid Autoimmunity in Men
Published 2020-01-01“…A total of 2253 residents who had lived in Xinjiang for more than 3 years were enrolled. Serum thyroid hormone concentration, thyroid autoantibodies, lipid parameters, Weight, height, and waist and hip circumference were measured. …”
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1729
Melatonin Enhances Maize Germination, Growth, and Salt Tolerance by Regulating Reactive Oxygen Species Accumulation and Antioxidant Systems
Published 2025-01-01“…Melatonin (MT) is a crucial hormone that controls and positively regulates plant growth under abiotic stress, but the biochemical and physiological processes of the combination of melatonin seed initiation and exogenous spray treatments and their effects on maize germination and seedling salt tolerance are not well understood. …”
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1730
A Case of Nonfunctioning Pituitary Carcinoma That Responded to Temozolomide Treatment
Published 2012-01-01“…Pituitary carcinomas commonly produce either PRL or ACTH, but some do not produce pituitary hormones. The alkylating reagent temozolomide (TMZ) was recently shown to be effective as a treatment for pituitary carcinoma. …”
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1731
Identification of selective SWI/SNF dependencies in enzalutamide-resistant prostate cancer
Published 2025-02-01“…Abstract Enzalutamide is a potent second-generation antiandrogen commonly used to treat hormone-sensitive and castration-resistant prostate cancer (CRPC) patients. …”
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1732
The Effects of 5-Hydroxytryptophan in Combination with Different Fatty Acids on Gastrointestinal Functions: A Pilot Experiment
Published 2014-01-01“…Diverse FAs have different effects on GE and secretion of orexigenic and anorexigenic hormones. Supplementation of 5-HTP had no effect on plasma serotonin and central functions. …”
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1733
Integrated analysis of transcriptome, sRNAome, and degradome involved in the drought-response of maize Zhengdan958
Published 2025-01-01“…These target genes were mainly involved in the plant hormone signal transduction and phenylpropanoid biosynthesis pathways. …”
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1734
Parathyroid Adenoma - The Leading Cause of Primary Hyperparathyroidism: Case Report
Published 2025-01-01“… Primary hyperparathyroidism is an endocrine disorder characterized by excessive secretion of parathyroid hormone (PTH) by the parathyroid glands, disproportionate to the physiological requirement for calcium concentration. …”
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1735
Protocol of a randomised trial of teriparatide followed by zoledronic acid to reduce fracture risk in adults with osteogenesis imperfecta
Published 2023-11-01“…The Treatment of Osteogenesis Imperfecta with Parathyroid Hormone and Zoledronic Acid trial will determine if therapy with teriparatide (TPTD) followed by zoledronic acid (ZA) can reduce the risk of clinical fractures in OI.Methods and analysis Individuals aged ≥18 years with a clinical diagnosis of OI are eligible to take part. …”
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1736
Melatonin supplementation for the treatment of infantile spasms: protocol for a randomised placebo-controlled triple-blind trial
Published 2022-07-01“…Patients will be randomly divided into two equal groups and treated with a combination of adrenocorticotropic hormone, magnesium sulfate and either melatonin or placebo. …”
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1737
The Impact of Thyme and Rosemary on Prevention of Osteoporosis in Rats
Published 2019-01-01“…Blood samples were collected for different biochemical analyses in plasma (calcium (Ca), phosphorus (P), magnesium (Mg), tumor necrosis factor-alpha (TNF-α), C-reactive protein (CRP), malondialdehyde (MDA), parathyroid hormone (PTH), C-terminal telopeptide (CTX), and 1,25-(OH)2-vitamin D3). …”
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1738
Genome-Wide Identification of the CIPK Gene Family in Jasmine and Expression Analysis Under Salt Stress
Published 2025-01-01“…Collinearity analysis demonstrated that 13 gene pairs in Arabidopsis were collinear with the jasmine sequences. Various hormone-related response- and stress-induced elements were observed in the promoter region of <i>JsCIPK</i> genes, such as TC-rich repeats, CARE, etc. …”
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1739
Efficacy of uterine flushing with human chorionic gonadotropin (hCG) on pregnancy rates in primary unexplained infertility: a randomized controlled trial
Published 2024-12-01“…Both groups received initial treatment with letrozole and Recombinant follicle-stimulating hormone (r-FSH). After confirmation of at least one follicle measuring 18 mm or larger through ultrasonography, in the control group, two ampoules of 5000 units of hCG were administered intramuscularly. …”
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1740
Maternal Vitamin D Status and Its Effect on Vitamin D Levels in Early Infancy in a Tertiary Care Centre in Sri Lanka
Published 2019-01-01“…Blood was collected for 25(OH)D and parathyroid hormone (PTH). Sun exposure and feeding patterns of the infants were recorded based on maternal reporting. …”
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