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1581
Systematic review of the association between thyroid disorders and hyperprolactinemia
Published 2025-01-01“…Patients with pituitary enlargement on imaging had a higher TSH level compared to those without any pituitary enlargement (Median of 263 (61–602) vs. 50 (24.3–128) mU/L; p-value = 0.01). Conclusion Thyroid hormone replacement can lead to resolution of HPRL and pituitary enlargement in the majority of patients with HPRL due to overt or subclinical hypothyroidism without the need for dopamine agonist treatment.…”
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1582
The Role of Prolactin as a Disease Activity Indicator in Some Rheumatic Diseases
Published 2025-07-01“…Background: Autoimmune rheumatic diseases, including rheumatoid arthritis (RA), systemic lupus erythematosus (SLE), and scleroderma, predominantly affect women and are characterized by systemic inflammation, leading to organ failure. Prolactin (PRL), a hormone produced by the pituitary gland and lymphocytes, significantly affects immune regulation and is implicated in the pathophysiology of these diseases. …”
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1583
Study of Postprandial Lipaemia in Type 2 Diabetes Mellitus: Exenatide versus Liraglutide
Published 2014-01-01“…Therapeutic approaches based on the actions of the incretin hormone GLP-1 have been widely established in the management of T2DM. …”
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1584
Impact of the COVID-19 pandemic on cerebral venous sinus thrombosis in China: a comparative study
Published 2025-01-01“…Poor outcomes were associated with central nervous system (CNS) infection, oral contraceptive use or hormone replacement therapy (HRT), hematologic disorders, anemia, and prothrombotic conditions. …”
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1585
Identifying MTHFD1 and LGALS4 as Potential Therapeutic Targets in Prostate Cancer Through Multi-Omics Mendelian Randomization Analysis
Published 2025-01-01“…The treatment of it is currently based on surgical removal, radiotherapy, and hormone therapy. It is crucial to improve therapeutic prospects for the diagnosis and treatment of prostate cancer via drug target screening. …”
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1586
A Nonfunctioning Pituitary Macroadenoma Presenting as Cyclical Vomiting and Severe Hyponatremia in a Young Female
Published 2021-01-01“…Nonfunctioning pituitary macroadenomas generally present with visual disturbances, headache, and symptoms due to anterior pituitary hormone deficiencies. This case report is about an atypical presentation of a nonfunctioning pituitary macroadenoma in which the patient presented with cyclical vomiting with severe hyponatremia. …”
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1587
Combined extracts of Syzygium aromaticum (Clove) and Xylopia aethiopica (Negro pepper) seeds inhibit testosterone propionate-induced benign prostatic hyperplasia in Wistar rats
Published 2024-12-01“…Conclusion: The mechanisms of BPH inhibition involve the regulation of sex hormone levels and the amelioration of conditions caused by oxidative damage. …”
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1588
Correlation Between Vitamin D3 Levels, Autoantibodies, and Antibody-Related Diseases in Patients with Hashimoto's Thyroiditis
Published 2024-12-01“…Various biomarkers to thyroid gland were measured, including thyroid -stimulating hormone (TSH), free thyroxine (T4), free triiodothyronine (T3). …”
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1589
GnRH Agonist versus hCG Trigger in Ovulation Induction with Intrauterine Insemination: A Randomized Controlled Trial
Published 2019-01-01“…This study is aimed at comparing clinical pregnancy rates (CPRs) in patients who are administered either gonadotropin-releasing hormone agonist (GnRHa) or human chorionic gonadotropin (hCG) for ovulation trigger in intrauterine insemination (IUI) cycles. …”
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1590
Immune checkpoint inhibitors-related thyroid dysfunction: influencing factor analysis, prediction model development, and management strategy proposal
Published 2024-11-01“…Results The systematic review encompassed 21 observational studies involving 4,145 patients, revealing associations between ICI-TD and factors such as female gender, age, receipt of Pembrolizumab (versus other ICIs), and baseline levels of thyroid-stimulating hormone, free thyroxine, and antithyroid antibodies. …”
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1591
Pruritus Features in Children with End-Stage Renal Disease Underwent Dialysis: A Cross-Sectional Study
Published 2021-01-01“…The distribution score of pruritus was directly correlated with the age (Spearman’s rho=0.42, P=0.02) and serum level of parathyroid hormone (PTH) (Spearman’s rho=0.42, P=0.04). In the reduced multiple logistic regression model, the increasing level of serum calcium was associated with increased odds of having total pruritus score≥5 (OR (odds ratio): 4.5; 95% CI 1.12 to 18.05). …”
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1592
Salvage Brachytherapy for Castration-Resistant and External Beam Radiotherapy-Resistant Local Recurrence 17 Years after Radical Prostatectomy
Published 2015-01-01“…The prescribed dose of the salvage brachytherapy was 145 Gy to control the tumor considering the hormone resistant prostatic cancer and high-risk feature. …”
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1593
Glucagon-Like Peptide-1 Triggers Protective Pathways in Pancreatic Beta-Cells Exposed to Glycated Serum
Published 2013-01-01“…Glucagon-like peptide-1 (GLP-1), an incretin hormone that regulates glucose homeostasis, might counteract the harmful effects of AGEs on the beta cells in culture. …”
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1594
Identification and characterization of soybean phytochrome-interacting factors and their potential roles in abiotic stress
Published 2024-12-01“…Abstract Phytochrome-interacting factors (PIFs) belong to a subfamily of the bHLH transcription factor family and play a pivotal role in plant light signal transduction, hormone signal pathways, and the modulation of plant responses to various abiotic stresses. …”
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1595
Urine metabolic profile in rats with arterial hypertension of different genesis
Published 2024-05-01“…To identify metabolomic markers for hypertensive conditions of different origins, three forms of arterial hypertension (AH) were studied: rats with hereditary AH (ISIAH rat strain); rats with AH induced by L-NAME administration (a model of endothelial dysfunction with impaired NO production); rats with AH caused by the administration of deoxycorticosterone in combination with salt loading (hormone-dependent form – DOCAsalt AH). WAG rats were used as normotensive controls. 24-hour urine samples were collected from all animals and analyzed by quantitative NMR spectroscopy for metabolic profiling. …”
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1596
Genetic basis of depressive disorders
Published 2019-07-01“…In addition, there is evidence of the involvement of HPA-axis genes (OXTR, AVPR1A, and AVPR1B), sex hormone receptors genes (ESR1, ESR2, and AR), neurotrophin (BDNF) and methylenetetrahydrofolate reductase (MTHFR) genes, neuronal apoptosis (CASP3, BCL-XL, BAX, NPY, APP, and GRIN1) and inflammatory system (TNF, CRP, IL6, IL1B, PSMB4, PSMD9, and STAT3) genes in DD development. …”
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1597
Risk Factors Associated with Breast Cancer in Women in a Health Area
Published 2023-11-01“…Breast cancer was considered as the dependent variable; the following were used as independent variables: age, personal and family pathological history, early menarche, late menopause, nulliparity, age of the first child, exclusive breastfeeding, replacement or replacement hormone therapy, use of contraceptive methods, obesity, sedentary lifestyle, smoking, alcoholism. …”
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1598
The correlation between the expression of androgen receptor splice variant-7 (AR-V7) protein with the time of occurrence of castration-resistant prostate cancer and overall surviva...
Published 2025-02-01“…Abstract Introduction Prostate cancer follows a natural trajectory characterized by genetic alterations that transform initially hormone-sensitive cancer cells into castration-resistant prostate cancer (CRPC), which is associated with high mortality. …”
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1599
Reveal the pharmacodynamic substances and mechanism of an edible medicinal plant Rhodiola crenulate in DSS-induced colitis through plasma pharmacochemistry and metabolomics
Published 2024-07-01“…The metabolomics study revealed that colitis caused the alternation of fatty acid metabolism, steroid hormone biosynthesis and bile acid metabolism. Correspondingly, RCE could prevent colitis by improving fatty acid metabolism and secondary bile acid metabolism.…”
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1600
False Positive Radioiodinated Metaiodobenzylguanidine (123I-MIBG) Uptake in Undifferentiated Adrenal Malignant Tumor
Published 2015-01-01“…Abdominal computed tomography (CT) revealed a heterogeneous left adrenal mass 6 cm in diameter; following hormone testing, 123I-MIBG scintigraphy was performed to determine the presence of pheochromocytoma, which confirmed eccentric uptake by a large left adrenal gland mass. …”
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