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1041
An unusual mediastinal giant parathyroid adenoma: A rare case report
Published 2025-04-01“…We present a case of 68-year-old asymptomatic male patient who had hypercalcemia and markedly high parathyroid hormone level on routine blood testing. Radiological investigations demonstrated a large mediastinal mass that showed peripheral high uptake on sestamibi scan. …”
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1042
Therapeutic Potential of Retinoid X Receptor Modulators for the Treatment of the Metabolic Syndrome
Published 2007-01-01“…However, undesirable side effects such as hypertriglyceridemia and suppression of the thyroid hormone axis also occur. This review examines and compares the effects of four RXR-selective ligands: LGD1069, LG100268, AGN194204, and LG101506, a selective RXR modulator. …”
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1043
The Role of Peroxisome Proliferator-Activated Receptors in Colorectal Cancer
Published 2012-01-01“…Dietary fat intake is a major risk factor for colorectal cancer. Some nuclear hormone receptors play an important role in regulating nutrient metabolism and energy homeostasis. …”
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1044
Relationship between Fibroblast Growth Factor-23 and Mineral Metabolism in Chronic Kidney Disease
Published 2010-01-01“…Both Klotho and FGF-23, linked by a receptor mechanism, affect vitamin D synthesis and parathyroid hormone (PTH) secretion. Previous studies have shown a close association between reduced FGF-23 or Klotho activities and vascular calcification. …”
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1045
Management of Zinner’s Syndrome Associated with Contralateral Seminal Vesicle Hypoplasia: A Case Report
Published 2013-01-01“…Physical examination, transrectal ultrasonography, and pelvic magnetic resonance imaging (MRI) demonstrated left seminal vesicle cyst, left renal agenesia, and contralateral seminal vesicle hypoplasia. Hormone workup (LH, FSH, prolactin, and testosterone) was normal. …”
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1046
The Role of Peroxisome Proliferator-Activated Receptors in Pulmonary Vascular Disease
Published 2007-01-01“…Peroxisome proliferator-activated receptors (PPARs) are ligand-activated transcription factors belonging to the nuclear hormone receptor superfamily that regulate diverse physiological processes ranging from lipogenesis to inflammation. …”
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1047
聚乙二醇修饰羊生长激素的初步研究
Published 1992-01-01“…使用非抗原性聚乙二醇(PEG)修饰羊生长激素(OVine growth hormone,oGH),分别获得氨基修饰率为35%和86%的PEG-oGH。氨基修饰率为35%的PEG-oGH仍保留了与天然oGH抗血清的反应性,但修饰率为86%的PEG-oGH则丧失了。…”
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1048
Severe Hypoglycemia due to Isolated ACTH Deficiency in Children: A New Case Report and Review of the Literature
Published 2011-01-01“…There was no evidence of other pituitary hormone deficiency. Glucocorticoid replacement therapy resulted in resolution of all symptoms and normalization of blood glucose. …”
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1049
Clinical and Biochemical Manifestations of Depression: Relation to the Neurobiology of Stress
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1050
The Role of PPARγ in the Transcriptional Control by Agonists and Antagonists
Published 2012-01-01“…We recently observed that cPA negatively regulates PPARγ function by stabilizing the binding of the corepressor protein, silencing mediator of retinoic acid and thyroid hormone receptor. We also showed that cPA prevents neointima formation, adipocyte differentiation, lipid accumulation, and upregulation of PPARγ target gene transcription. …”
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1051
Leptin Promotes Glioblastoma
Published 2012-01-01“…The hormone leptin has a variety of functions. Originally known for its role in satiety and weight loss, leptin more recently has been shown to augment tumor growth in a variety of cancers. …”
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1052
Complete Androgen Insensitivity Syndrome: A Rare Case of Disorder of Sex Development
Published 2013-01-01“…Androgen Insensitivity Syndrome (AIS) could be considered as a disease that causes resistance to androgens actions, influencing both the morphogenesis and differentiation of the body structures, and systems in which this hormone exerts its effects. It depends on an X-linked mutations in the Androgen Receptor (AR) gene that express a variety of phenotypes ranging from male infertility to completely normal female external genitalia. …”
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1053
An Optimized Protocol for Simultaneous Propagation of Patient-derived Organoids and Matching CAFs
Published 2025-01-01“…Recurrent hormone receptor-positive (HR+) breast cancer is a leading cause of cancer mortality in women. …”
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1054
Pulmonary Embolism as a Rare Complication of Clomiphene Therapy: A Case Report and Literature Review
Published 2021-01-01“…Certain medications like oral contraceptives and hormone replacement therapies have been associated with PE. …”
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1055
Osteoporosis Syndrome in Thalassaemia Major: An Overview
Published 2010-01-01“…Peak bone mass is achieved shortly after completion of puberty and normally remains stable until the third decade of life when age-related bone mass begins. Growth hormone (GH) and sex steroids play a crucial role in bone remodeling and in the maintenance of skeletal architecture during adult life. …”
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1056
A Case of Acute Psychosis in an Adolescent Male
Published 2014-01-01“…We report the case of a 17-year-old adolescent male, who presented with an acute psychosis coinciding with severe hypercalcemia and markedly elevated intact parathyroid hormone (iPTH) level and low vitamin D level. A Sestamibi scan showed a positive signal inferior to the left lobe of the thyroid gland. …”
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1057
Exploring the Role of Estrogens in Lizard Spermatogenesis through the Study of Clomiphene and FSH Effects
Published 2017-01-01“…Increasing evidence suggests that the primary female sex hormone estrogen plays an active role in this process. …”
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1058
Gland New Psychosis: New Onset Adult Psychosis with Suicidal Ideation and Attempt in the Setting of Thyroid Storm
Published 2017-01-01“…Treatment of the thyroid hormone overload resulted in a rapid resolution of her symptoms; she was discharged in excellent condition, and she has had no repeat hallucinations or self-injury ideation or attempts since. …”
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1059
Ectopic Lingual Thyroid
Published 2015-01-01“…Evolution has been favourable and the patient showed significant improvement with reduction of the dyspnea and the dysphagia and normalization of thyroid hormone tests.…”
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1060
Growth Retardation in Children with Kidney Disease
Published 2013-01-01“…This review covers updated management of growth failure in these children including adequate nutrition, treatment of metabolic alterations, and early administration of recombinant human growth hormone (GH).…”
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