Risk and protective factors associated with adolescent depression in Singapore: a systematic review by Wei Sheng Goh, Jun Hao Norman Tan, Yang Luo, Sok Hui Ng, Mohamed Sufyan Bin Mohamed Sulaiman, John Chee Meng Wong, Victor Weng Keong Loh

“…The four factors associated with adolescent depression identified were: (1) sociodemographic factors (gender, ethnicity); (2) psychological factors, including childhood maltreatment exposure and psychological constructs (hope, optimism); (3) coexisting chronic medical conditions (asthma); and (4) lifestyle factors (sleep inadequacy, excessive internet use and pathological gaming). …”
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The Noble Suicide: The Case of a Self-Contained Dagger in the Heart and a Literal Raw by Maricla Marrone, Benedetta Pia De Luca, Marco Papalino, Fortunato Pititto, Carlo Angeletti, Roberto Bellacicco, Michela Raino, Giuseppe Pulin, Francesca Tarantino

“…The man decided to commit suicide because he could no longer find meaning in his life after losing hope for a career as a pianist, having been diagnosed with a degenerative disease in his hands. …”
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Is a Consensus Case Definition for Viral Associated Lower Respiratory Tract Disease (LRTD) in Clinical Trials Possible? by S. Elizabeth Williams, Bradford Gessner, Elizabeth Begier, Negar Aliabadi, Kumar Ilangovan, Luis Jodar, Cassandra Hall-Murray, Giovanni Checcucci Lisi, Edward Walsh

“…Here we review the key differences in criteria for case definitions, highlight strategies to best approximate compatibility between definitions, and review vaccine efficacy results among currently US Food and Drug Administration (FDA)-approved vaccines using these strategies. We hope this overview will support the need to develop a consensus definition for LRTI/LRTD to improve future research related to viral respiratory disease.…”
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Digitalization of public administration: expert reflection on problems and challenges by E. I. Boev, V. V. Zotov, L. A. Vasilenko

“…Based on the analysis of the results of the expert survey, the authors conclude that the digitalization of the activities of the authorities gives a good increase not only in improving the quality of service provision to the country’s population, but also in improving the feedback mechanism, increasing the involvement of the population in the process of solving socially significant issues. This gives hope that the resolution of problems associated with the introduction of digital technologies into the work of government bodies with the population will contribute to the transition from informing and servicing citizens to interactive communication with them.…”
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What are biopharmaceuticals? by Abhay H. Pande, Yenisetti Rajendra Prasad, J. Anakha

“…Modern manufacturing processes and streamlined regulatory pathways have further expedited approval timelines, providing hope for previously untreatable conditions and significantly improving patients’ quality of life worldwide. …”
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FDA’s approval of resmetirom (Rezdiffra): a breakthrough in MASH management by Muhammad Mazhar Azam, Sameen Mukhtar, Muhammad Haris, Fatima Laique, Suhaina Amir, Mubashir Mohiuddin, Bibek Giri

“…As the first FDA-approved drug for MASH, resmetirom’s introduction fills a crucial treatment gap, providing new hope for millions of patients and representing a pivotal moment in hepatology.…”
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Exhausting the (Human) Problem by Annalaura Alifuoco

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Sepsis subphenotypes: bridging the gaps in sepsis treatment strategies by Xue Zhang, Wei Zhang, Huan Zhang, Xuelian Liao, Xuelian Liao

“…By investigating phenotypic variation in therapy responses, we hope to uncover new biomarkers and phenotype-driven therapeutic solutions, laying the groundwork for more effective therapies and, ultimately improving patient outcomes.…”
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Sustainability in higher education: Comparison of the Asia-Pacific region and Serbia by Đukić Gordana, Ilić Biljana

“…Regardless of environmental and humanitarian problems, there is hope that man will be able to react in the right way, with a greater understanding of the dynamics of natural and social processes. …”
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An Evaluation Of The Enjoyment Levels Of Participants Of LifeLab, A Health Literacy Intervention For Socially Disadvantaged Adolescents. by Lorna Burke, Dr. Hannah Goss, Craig Smith, Dr. Johann Issartel, Dr. Sarahjane Belton

“…Aim: LifeLab is co-designed by and for Junior Cycle students from social disadvantage in Ireland, with the hope to improve health literacy and subsequent health outcomes in this cohort. …”
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Metabolic engineering approaches for the biosynthesis of antibiotics by Geunsoo Yook, Jiwoo Nam, Yeonseo Jo, Hyunji Yoon, Dongsoo Yang

“…Conclusion These metabolic engineering and synthetic biology strategies offer promising potential to revitalize the discovery and development of new antibiotics, providing renewed hope in humanity’s fight against MDR pathogenic bacteria.…”
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The Expanding Role for Retinoid Signaling in Heart Development by Loretta L. Hoover, Elizabeth G. Burton, Bonnie A. Brooks, Steven W. Kubalak

“…This review summarizes many of the significant milestones in this field and particular attention is given to recently uncovered cross-talk between retinoid signaling and other developmentally significant pathways. It is our hope that this review of the role of retinoid signaling during formation, remodeling, and maturation of the developing heart will serve as a tool for future discoveries.…”
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Role of heat shock protein in radiation-induced effect and related potential clinical application by Ying Xu, Wentao Hu, Guangming Zhou

“…This paper reviews the biological effects of HSP under radiation and the latest research progress of combined radiation and HSP inhibitors or hyperthermia, in the hope of having a more comprehensive understanding of its mechanism in physiological processes such as cell survival, apoptosis, inflammation, immune response, as well as radiation response, which will help to enhance the therapeutic effect and to provide more effective and safer radiotherapy for cancer patients in the future.…”
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Microseismic Monitoring, Positioning Principle, and Sensor Layout Strategy of Rock Mass Engineering by Tianhui Ma, Daoyuan Lin, Chun’an Tang, Kedar Prasad Yadav, Zhiqiang Feng, Ke Ma

“…In this paper, the fracture and instability of rock can be analyzed by analyzing the microseismic signals produced by rock failure; The location of microseismic source can be determined by multipoint synchronous data acquisition to determine the time when each sensor (at least 5) receives microseismic signals; Combined with practical engineering experience for underground engineering in growth, heading tunnel, put forward only sensor arrangement to take mobile, follow the semienclosed layout network. We hope to give some reference to the researchers who are concerned with microseismic monitoring technology.…”
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Are Believers Happier than Atheists? Well-being Measures in a Sample of Atheists and Believers in Puerto Rico by Juan Aníbal González-Rivera, Adam Rosario-Rodríguez, Eduardo L. Rodríguez-Ramos, Idania Hernández-Gato, Lourdes M. Torres-Báez

“…This study provides empirical evidence to demystify certain traditional assumptions about the supremacy of religious beliefs over secular convictions or vice versa. We hope that these findings create social awareness and could be used as a basis for future research concerning the population of non-believers…”
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Marked Rebound of Platelet Count in the Early Postpartum Period in a Patient with Essential Thrombocythemia by Yoshinori Hashimoto, Rina Hosoda, Hiromi Omura, Takayuki Tanaka

“…It remains unknown whether the platelet count will decrease after some time without treatment if it rebounds. We hope management guidelines will be established by collecting detailed data on the postpartum course as well as during pregnancy.…”
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Quality of public services in the field of population administration in malang public administrative mall by Didik Supriyanto

“…If we are honest, there is hope that people's satisfaction is a measure of the success of public services provided by the government as a public service provider. …”
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Gamisoyo-San Ameliorates Neuroinflammation in the Spinal Cord of hSOD1G93A Transgenic Mice by MuDan Cai, Eun Jin Yang

“…Therefore, patients with ALS often turn to complementary and alternative medicine, such as acupuncture, homeopathy, and herbal medicine, with the hope and belief of recovery, despite the lack of definite evidence on the efficacy of these methods. …”
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Fungal Infection following Total Elbow Arthroplasty by Samuel S. Ornell, Khang H. Dang, Aaron J. Bois, Anil K. Dutta

“…With our case report, we hope to contribute to the overall knowledge of fungal infections associated with TEA and describe our successful treatment of this complex case.…”
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Neoantigen immunotherapy: a novel treatment for bladder cancer by Ruiyang Lv, Zhenzhu Liu, Maoxin Lv, Yuze Song, Junlin Wang, Huizhi Mu, Yu Zhang, Xuejian Wang

“…Over recent years, the rapid development of tumor immunotherapy has become a significant alternative to traditional treatment, and provides new hope to patients. This review aims to introduce neoantigens and their possible role in the treatment of bladder cancer, and to explore the current limitations of neoantigens for the treatment of bladder cancer.…”
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