Survival analysis of a 16-year cohort of follicular lymphoma patients receiving systemic treatment in Brazil by Pamela Santos Azevedo, Isabella Zuppo Laper, Deborah Marta do Santos Oliveira, Adriano de Paula Sabino, Marina Morgado Garcia, Isabela Cristina Menezes de Freitas, Isabela Cristina Menezes de Freitas, Wallace Mateus Prata, Wallace Mateus Prata, Mariângela Leal Cherchiglia, Juliana Álvares-Teodoro, Juliana Álvares-Teodoro, Francisco de Assis Acurcio, Francisco de Assis Acurcio, Augusto Afonso Guerra Júnior, Augusto Afonso Guerra Júnior

“…IntroductionFollicular lymphoma (FL) is a common type of non-Hodgkin lymphoma that is incurable but often follows an indolent course. …”
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Impact of circulating lymphoma cells at diagnosis on outcomes in patients with newly diagnosed de novo diffuse large B-cell lymphoma by Sayan Mullick Chowdhury, Subodh Bhatta, Timothy J. Voorhees, Kaitlin Annunzio, David A. Bond, Yazeed Sawalha, Audrey Sigmund, Walter Hanel, Lalit Sehgal, Lapo Alinari, Robert Baiocchi, Kami Maddocks, Beth Christian, Dan Jones, Narendranath Epperla

“…Abstract Diffuse large B-cell lymphoma (DLBCL), the most common B-cell non-Hodgkin lymphoma rarely presents with circulating lymphoma cells (CL) at diagnosis. …”
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Sporadic Burkitt Lymphoma First Presenting as Painful Gingival Swellings and Tooth Hypermobility: A Life-Saving Referral by Erofili Papadopoulou, Maria Kouri, Dimitrios Velonis, Anastasia Andreou, Maria Georgaki, Spyridon Damaskos, Evangelia Piperi, Konstantina Delli, Ioannis K. Karoussis, Antonia Vlachou, Georgia Avgerinou, Antonis Kattamis, Nikolaos G. Nikitakis

“…<b>Background:</b> Burkitt lymphoma (BL) is an aggressive non-Hodgkin lymphoma (NHL), subdivided into endemic, sporadic, and immunodeficiency-associated forms. …”
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Patient-derived follicular lymphoma spheroids recapitulate lymph node signaling and immune profile uncovering galectin-9 as a novel immunotherapeutic target by Cèlia Dobaño-López, Juan García Valero, Ferran Araujo-Ayala, Ferran Nadeu, Fabien Gava, Carla Faria, Marine Norlund, Renaud Morin, Pascale Bernes-Lasserre, Fabian Arenas, Marta Grau, Cristina López, Irene López-Oreja, Neus Serrat, Ares Martínez-Farran, Lluís Hernández, Heribert Playa-Albinyana, Rubén Giménez, Silvia Beà, Elías Campo, Jean-Michel Lagarde, Armando López-Guillermo, Laura Magnano, Dolors Colomer, Christine Bezombes, Patricia Pérez-Galán

“…Abstract Follicular lymphoma (FL), the most common indolent non-Hodgkin lymphoma, constitutes a paradigm of immune tumor microenvironment (TME) contribution to disease onset, progression, and heterogenous clinical outcome. …”
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Comparison of differences in transcriptional and genetic profiles between intra-central nervous system and extra-central nervous system large B-cell lymphoma by Shu Wang, Hong Chen, Bo Dai, Kang Zheng, Jiajun Zheng, Yuqi Zhu, Yan Yuan, Tianling Ding, Qian Wang, Liqian Xie, Rui Feng, Fengping Zhu, Jianbin Xiang, Weiqun Ding, Hong Ding, Yuan Li, Xiaodong Gu, Kunpeng Wu, Yifan Yuan, Jianping Song, Dongxiao Zhuang, Haoshu Zhong, Hanfeng Wu, Ying Mao, Tong Chen

“…Primary central nervous system diffused large B-cell lymphoma (PCNS-DLBCL) is a rare type of non-Hodgkin lymphoma restricted to the central nervous system (CNS). …”
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A Challenging Case of Kikuchi-Fujimoto Disease Associated with Systemic Lupus Erythematosus and Review of the Literature by Mihaela Găman, Ana-Maria Vlădăreanu, Camelia Dobrea, Minodora Onisâi, Cristina Marinescu, Irina Voican, Daniela Vasile, Horia Bumbea, Diana Cîşleanu

“…Kikuchi–Fujimoto disease (KFD) or histiocytic necrotizing lymphadenitis is a rare disease that is frequently underdiagnosed due to clinical features that are similar to those of non-Hodgkin lymphomas, systemic lupus erythematosus (SLE), or infectious reactive lymphadenopathy. …”
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Rituximab-Induced Coronary Vasospasm by Linda Lee, Vishal Kukreti

“…Rituximab has improved the treatment of B-cell non-Hodgkin lymphomas. While it is generally well tolerated, serious adverse effects including infusion reactions with hemodynamic compromise and cardiac arrhythmias or ischemia are possible. …”
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CAR-T therapy toxicities: the importance of macrophages in their development and possible targets for their management by Joseph Norton, Patrick Stiff

“…Abstract CAR-T cell therapies have risen to prominence over the last decade, and their indications are increasing with several products approved as early as second line in Large B Cell non-Hodgkin Lymphomas. Their major toxicities are the cytokine release syndrome (CRS) and the Immune-effector Cell Associated Neurotoxicity Syndrome (ICANS). …”
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Primary Cutaneous CD 30+ Anaplastic Large Cell Lymphoma. A Case Report and Literature Review by Miguel Ángel Serra Valdés, Julian Manzur Katrib, Yordanka Aleaga Hernández

“…It accounts for a very small proportion of non-Hodgkins lymphomas. The case of an 80-year-old female patient whose diagnosis was established in 2006 because of lesions on the face and neck is presented. …”
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Characterization of Follicular Lymphoma in the Small Intestine Using Double-Balloon Endoscopy by Manzurul Chowdhury, Masaki Endo, Toshimi Chiba, Norihiko Kudara, Shuhei Oana, Kunihiko Sato, Risaburo Akasaka, Kazumitsu Tomita, Saori Fujiwara, Tomomi Mizutani, Tamotsu Sugai, Yasuhiro Takikawa, Kazuyuki Suzuki

“…Follicular lymphomas occur rarely in the gastrointestinal tract, representing only 1–3% of all gastrointestinal tract B-cell non-Hodgkin lymphomas. We describe endoscopic analysis of 3 cases of follicular lymphoma in the small intestine using double-balloon endoscopy. …”
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CAR-T Therapy Beyond B-Cell Hematological Malignancies by Martina Canichella, Paolo de Fabritiis

“…Despite the advances of CAR-T cells in certain hematological malignancies, mostly from B-cell derivations such as non-Hodgkin lymphomas, acute lymphoblastic leukemia and multiple myeloma, a significant portion of other hematological and non-hematological pathologies can benefit from this innovative treatment, as the results of clinical studies are demonstrating. …”
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A Rare Case of Primary Bilateral Adrenal Lymphoma by Veeraraghavan Meyyur Aravamudan, Phang Kee Fong, Yang Shiyao Sam, Pavel Singh, Siok-Bian Ng, Gollamudi Satya Pavan Kumar

“…Primary adrenal lymphoma is extremely rare, accounting for <1% of non-Hodgkin lymphomas. We here present a case of a middle-aged female who presented with persistent fever for three weeks. …”
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Molecular Pathogenesis of MALT Lymphoma by Katharina Troppan, Kerstin Wenzl, Peter Neumeister, Alexander Deutsch

“…Approximately 8% of all non-Hodgkin lymphomas are extranodal marginal zone B cell lymphoma of mucosa associated lymphoid tissue (MALT), also known as MALT lymphoma, which was first described in 1983 by Isaacson and Wright. …”
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Long-Term Treatment with Romidepsin in Patients with Peripheral T-Cell Lymphoma by Claudius Irlé, Jonathan Weintraub

“…Peripheral T-cell lymphomas (PTCLs) are a heterogeneous group of aggressive non-Hodgkin lymphomas. Angioimmunoblastic T-cell lymphoma (AITL) is a common subtype of PTCL, and patients with AITL typically have a poor prognosis with limited treatment options. …”
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Morphologic Features of Extrahepatic Manifestations of Hepatitis C Virus Infection by Huaibin M. Ko, Juan C. Hernandez-Prera, Hongfa Zhu, Steven H. Dikman, Harleen K. Sidhu, Stephen C. Ward, Swan N. Thung

“…Other HCV-associated entities include porphyria cutanea tarda, lichen planus, necrolytic acral erythema, membranous glomerulonephritis, diabetic nephropathy, B-cell non-Hodgkin lymphomas, insulin resistance, sialadenitis, sicca syndrome, and autoimmune thyroiditis. …”
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Prognostic Assessment in Patients with Indolent B-Cell Lymphomas by Luca Arcaini, Sara Rattotti, Manuel Gotti, Stefano Luminari

“…In 2004, an international consortium coordinated by the International Follicular Lymphoma Prognostic Factor project was established and a new prognostic study was launched (FLIPI2) using progression-free survival (PFS) as main endpoint and integrating all the modern parameters prospectively collected. Low-grade non-Hodgkin lymphomas were once considered as a heterogenous group of lymphomas characterized by an indolent clinical course. …”
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CAR-T CELLS IN CHRONIC LYMPHOCYTIC LEUKEMIA by Ugo Testa, Elvira Pelosi, Germana Castelli, Alberto Fresa, Luca Laurenti

“…Among these new treatments, a potentially curative approach consists of the use of chimeric antigen receptor T (CAR-T) cell therapy, which achieved remarkable success in various B-cell malignancies, including B-cell Non-Hodgkin Lymphomas (NHLs) and B-acute lymphoblastic Leukemia (ALL). …”
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Ewing’s Sarcoma of the Lung as a Second Malignancy in Long-Term Survivor of Childhood Hodgkin’s Lymphoma: A Rare Case Report and Literature Review by Sumit Bharti, Deepak Bhasin, Gautam Goyal, Priya Sharma

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Unusual Case of Anaplastic Large Cell Lymphoma Presenting as a Breast Mass in a Patient with no History of Breast Implants by Yana Ivashkevich, Yaroslav Chernov, Denis Chinenov, Evgeniy Shpot, Alexander A. Bessonov, Arthy Yoga, Kirill A. Lyapichev, Sergej Konoplev

“…Traditionally, non-Hodgkin lymphomas (NHL) involving the breast are divided into primary lymphoma of the breast and systemic lymphoma, although the distinction could be challenging. …”
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Incidence and Evaluation of Incidental Abnormal Bone Marrow Signal on Magnetic Resonance Imaging by Gunjan L. Shah, Aaron S. Rosenberg, Jamie Jarboe, Andreas Klein, Furha Cossor

“…With median follow-up of 41 months, 6% of patients were diagnosed with malignancies including multiple myeloma, non-Hodgkins lymphoma, metastatic non-small cell lung cancer, and metastatic adenocarcinoma. …”
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