A Case of Mucosal Cancer of the Stomach Treated by Endoscopic Submucosal Dissection after Which Nodal Metastasis Became Evident by Takashi Obana, Naotaka Fujita, Yutaka Noda, Dai Hirasawa, Kei Ito, Toshiki Sugawara, Yoshihiro Harada, Tetsuya Oohira, Hiroshi Honda, Takashi Sawai

“…After discharge, he has been followed up at the outpatient department without any sign of recurrence for 5 years. Histological reexamination of the ESD specimen using immunohistochemistry showed lymphatic invasion of cancer cells in the lamina propria of the 0-I lesion 13 mm in size.…”
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Characterization and Etiopathogenic Approach of Pediatric Renal Biopsy Patients in a Colombian Medical Center from 2007-2017 by Mayerly Prada Rico, Carmen Inés Rodríguez Cuellar, Monica Fernandez Hernandez, Luz Stella González Chaparro, Olga Lucía Prado Agredo, Ricardo Gastelbondo Amaya

“…Immune complex glomerulonephritis was the most frequent histological finding, differing from previous reports. …”
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Immunocytochemical and Morphometric Studies of Gastrin-, Somatostatin- and Serotonin-Producing Cells in the Stomach and Duodenum of Patients with Acid Peptic Disorders by WR Yacoub, ABR Thomson, P Hooper, LD Jewell

“…Seven patients with minimal dyspeptic symptoms and an endoscopically and histologically normal stomach and duodenum served as controls. …”
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The Effect of Cyclooxygenase Inhibition on Tendon-Bone Healing in an In Vitro Coculture Model by Tim Schwarting, Sebastian Pretzsch, Florian Debus, Steffen Ruchholtz, Philipp Lechler

“…We measured the dose-dependent effects of ibuprofen and parecoxib on the viability of lipopolysaccharide- (LPS-) stimulated and unstimulated mouse MC3T3-E1 and 3T3 cells, the influence on gene expression at the osteoblast, interface, and fibroblast regions measured by quantitative PCR, and cellular outgrowth assessed on histological sections. Ibuprofen led to a dose-dependent suppression of MC3T3 cell viability, while parecoxib reduced the viability of 3T3 cultures. …”
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Therapeutic Angiogenesis Using Basic Fibroblast Growth Factor in Combination with a Collagen Matrix in Chronic Hindlimb Ischemia by Jianyin Zhou, Yilin Zhao, Jinling Wang, Sheng Zhang, Zhengjin Liu, Maochuan Zhen, Yun Liu, Pingguo Liu, Zhenyu Yin, Xiaomin Wang

“…Oxygen saturation parameters (OSP) of ischemic hindlimbs was measured to evaluate the extremity perfusion at intervals. Histological examination was performed to evaluate the level of angiogenesis. …”
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CTLA-4 and PD-1 Ligand Gene Expression in Epithelial Thyroid Cancers by Chiara Tuccilli, Enke Baldini, Salvatore Sorrenti, Antonio Catania, Alessandro Antonelli, Poupak Fallahi, Francesco Tartaglia, Susi Barollo, Caterina Mian, Andrea Palmieri, Giovanni Carbotta, Stefano Arcieri, Daniele Pironi, Massimo Vergine, Massimo Monti, Salvatore Ulisse

“…Higher expression of PD-L1 associated with the classical histological variant and with the presence of BRAFV600E mutation in PTC. …”
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Granulomatous Lung Disease Requiring Mechanical Ventilation Induced by a Single Application of Oxaliplatin-Based Chemotherapy for Colorectal Cancer: A Case Report by Dane Wildner, Frank Boxberger, Axel Wein, Kerstin Wolff, Heinz Albrecht, Gudrun Männlein, Rolf Janka, Kerstin Amann, Jürgen Siebler, Werner Hohenberger, Markus F. Neurath, Richard Strauß

“…Diagnostic thoracoscopic wedge resections were performed for further diagnosis. The histological workup revealed distinct granulomatous inflammation, but no microbial pathogens were to be found. …”
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Flavonoid-Rich Extract of Dissotis rotundifolia Whole Plant Protects against Ethanol-Induced Gastric Mucosal Damage by Michael Buenor Adinortey, Charles Ansah, Benjamin Aboagye, Justice Kwabena Sarfo, Orleans Martey, Alexander Kwadwo Nyarko

“…Gross examinations of the stomach lining and histological analysis of gastric lesions were carried out coupled with an assessment of the antioxidant activity of gastric mucosa using MDA, GSH, CAT, and SOD as indicators. …”
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Spinal CRH facilitates the micturition reflex via the CRH2 receptor in rats with normal bladder and bladder outlet obstruction by Risa Shinoki, Ryosuke Jikuya, Takuma Nirei, Takeshi Fukazawa, Hiroki Takizawa, Mari Hioki, Sachi Kawaura, Tomoyuki Tatenuma, Go Noguchi, Daiki Ueno, Yusuke Ito, Mitsuru Komeya, Kentaro Muraoka, Hisashi Hasumi, Kazuki Kobayashi, Masahito Takiguchi, Kengo Funakoshi, Kazuhide Makiyama, Naoki Aizawa, Hiroki Ito

“…Herein, we investigated the role of spinal CRH in regulating micturition in sham and BOO rats, and evaluated CRH as a therapeutic target for bladder dysfunction in BOO model Sprague–Dawley rats. Histological analysis, cystometry with intrathecal administration of CRH agonists/antagonists, western blotting, and real-time PCR assessed the role of CRH and its receptors (CRHR1 and CRHR2) in micturition in sham and BOO rats. …”
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Negative Influence of a Long-Term High-Fat Diet on Murine Bone Architecture by Hinrich Fehrendt, Thomas Linn, Sonja Hartmann, Gabor Szalay, Christian Heiss, Reinhard Schnettler, Katrin Susanne Lips

“…Four-week-old male C57BL/6J mice received a high-fat diet (HFD, 60% kcal from fat) and were analyzed by means of dual X-ray absorptiometry, histological methods, real-time RT-PCR, and transmission electron microscopy in comparison to control animals (10% kcal from fat). …”
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Early Invasive Cancer and Partial Intraoperative Electron Radiation Therapy of the Breast: Experience of the Jules Bordet Institute by C. Philippson, S. Simon, C. Vandekerkhove, D. Hertens, I. Veys, D. Noterman, F. De Neubourg, D. Larsimont, P. Bourgeois, P. Van Houtte, J. M. Nogaret

“…Inclusion criteria were unifocal invasive ductal carcinoma, age ≥40 years, histological tumour size ≤20 mm, and no lymph node involvement. …”
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Magnetic field-induced synergistic therapy of cancer using magnetoplasmonic nanoplatform by Siqi Gao, Iuliia Golovynska, Jiantao Liu, Zhenlong Huang, Hao Xu, Jinghan Qu, Fangrui Lin, Galyna Ostrovska, Junle Qu, Tymish Y. Ohulchanskyy

“…A combination of the MF induced NIR photothermal therapy (PTT) with DOX chemotherapeutic action resulted in an efficient killing of NPs treated cancer cells in vitro and tumor growth restriction in 4T1-tumor-bearing mice in vivo. Histological studies showed striking differences in development and malignancy between tumors treated with the combination of NPs, MF and an 808 nm laser, and the control treatments, revealing a synergy of the MF-induced NIR PTT and chemotherapy and suggesting a promising strategy for cancer therapy.…”
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The Involvement of Notch1-RBP-Jk/Msx2 Signaling Pathway in Aortic Calcification of Diabetic Nephropathy Rats by Caipan Gong, Li Li, Chunmei Qin, Weihua Wu, Qi Liu, Ying Li, Linwang Gan, Santao Ou

“…Biochemical analysis and histological examination of aortic tissue were performed. …”
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An Immunocompetent HIV-Negative Elderly Patient with Low-Grade Fever, Generalized Lymphadenopathy, Splenomegaly, and Acute Phase Response: Do Not Forget Castleman Disease by Kalliopi Azariadis, Maria Ioannou, Kalliopi Zachou, George N. Dalekos

“…Infectious causes including HIV were ruled out. Histological examination of a cervical lymph-node revealed lesions supportive of MCD diagnosis. …”
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In Vitro and In Ovo Evaluation of <i>Oenothera biennis</i> L. Oil as an Alternative Preservative for Oil-Based Products by Ramona Fecker, Ștefana Avram, Ileana Cocan, Ersilia Alexa, Larisa Bora, Daliana Minda, Ioana Zinuca Magyari-Pavel, Cristina Adriana Dehelean, Corina Danciu

“…Various methods were applied to assess oxidative stability by calculating the peroxide value, the <i>p</i>-anisidine value, and the total oxidation value, while biological safety was evaluated using the chick embryo’s chorioallantoic membrane and histological analysis. The findings highlight that evening primrose oil, with its balanced effects on epithelial tissues and vascularization, as well as its strong anti-lipid peroxidation properties, is a suitable alternative to synthetic preservatives when used in combination with cold-pressed oils. …”
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Ontogeny and function of the intestinal epithelial and innate immune cells during early development of chicks: to explore in ovo immunomodulatory nutrition by Habtamu Ayalew, Changchun Xu, Assefa Adane, Astrid Lissette Barreto Sanchez, Siman Li, Jing Wang, Shugeng Wu, Kai Qiu, Guanghai Qi, Haijun Zhang

“…The maturation and functionality of IECs are histologically evident starting embryonic day (ED) 14. …”
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Minimal differences observed when comparing the morphological profiling of microglia obtained by confocal laser scanning and optical sectioning microscopy by Sânziana Godeanu, Sânziana Godeanu, Mădălina Iuliana Mușat, Anja Scheller, Anja Scheller, Eugen Osiac, Bogdan Cătălin, Bogdan Cătălin

“…As such, OSM systems seem a valid option if one just wants basic histological evaluation, and cLSM should be considered for groups that demand higher resolution or volumetric images.…”
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Untypical Amlodipine-Induced Gingival Hyperplasia by Verica Pavlic, Nina Zubovic, Sanja Ilic, Tijana Adamovic

“…The clinical and the histological evidences were consistent with AIGO. The first line treatment consisted of the amlodipine substitution (amlodipine was replaced with enalapril, 5 mg/day) and the scaling and root planning/SRP. …”
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Increased Anti-Proliferation Performance of NanoChitosan-Moringa Seeds Extract and Co-Treatment with Doxorubicin in Liver Cancer Cells by Hendra Susanto, Moch Sholeh, Agustina Tri Endharti, Nik Ahmad Nizam Nik Malek, Sa’diyatul Rizqie Amaliyah Firdaus, Adeodatus Yuda Handaya, Ahmad Taufiq

“…Hep G2 showed a decrease in the expression level of each parameter measured with increasing single dose and combination treatment (p < 0.050). Histologically, cells shrank, betatrophin expression was inhibited, and luminescence was seen, which decreased with increasing dose. …”
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Single-nucleus transcriptomes reveal the underlying mechanisms of dynamic whitening in thermogenic adipose tissue in goats by Manman Li, Nange Ma, Shujie Luo, Yuyi Lu, Xixi Yan, Yang Li, Xinmei Li, Zhuohui Li, Zhipei Wu, Zhenyu Wei, Wei Wang, Huimei Fan, Yu Jiang, Yan Xiong, Yu Wang

“…In this study, we employed single-nucleus RNA-seq to construct a cell atlas during whitening progression and identified the characteristics of thermogenic adipocytes. Results Our histological studies and bulk transcriptome gene expression analysis confirmed that both perirenal and omental adipose tissues (pAT and oAT) exhibited progressive whitening in goats. …”
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