Image Analysis Based Grading of Bladder Carcinoma. Comparison of Object, Texture and Graph Based Methods and Their Reproducibility by Heung‐Kook Choi, Torsten Jarkrans, Ewert Bengtsson, Janos Vasko, Kenneth Wester, Per-Uno Malmström, Christer Busch

“…Object, texture and graph based analysis were carried out from Feulgen stained histological tissue sections. The object based features were extracted from gray scale images, binary images obtained by thresholding the nuclei and several other images derived through image processing operations. …”
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Intestinal permeability and contractility in murine colitis by M. E. van Meeteren, J. D. van Bergeijk, A. P. M. van Dijk, C. J. A. M. Tak, M. A. C. Meijssen, F. J. Zijlstra

“…Intestinal permeability in control vs. 10% DSS mice was not altered, although histologic inflammation score and IFN-γ pro-inflammatory cytokine levels were significantly increased in proximal and distal colon. …”
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Mast Cell Interaction with Neutrophils in Human Gastric Carcinomas: Ultrastructural Observations by Antonio Ieni, Valeria Barresi, Giovanni Branca, Rosario Alberto Caruso, Giovanni Tuccari

“…In addition, we found normal-appearing or early apoptosis showing neutrophils. Conclusion. Our histological findings showed the likely interaction between mast cells and neutrophils in GC. …”
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Adipose Derived Mesenchymal Stem Cells Efficiently Rescue Carbon Tetrachloride-Induced Acute Liver Failure in Mouse by Lisi Deng, Guangze Liu, Xin Wu, Yaping Wang, Minghua Tong, Bing Liu, Kuidong Wang, Yuting Peng, Xiangping Kong

“…The restoration of biological functions of the livers receiving transplantation was assessed via a variety of approaches such as survival rates, live function parameters, histological localization of EGFP-ADMSCs, and Immunofluorescence analysis. …”
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Local Gene Transfer of OPG Prevents Joint Damage and Disease Progression in Collagen-Induced Arthritis by Qingguo Zhang, Weiming Gong, Bin Ning, Lin Nie, Paul H. Wooley, Shang-You Yang

“…Clinical disease scores were significantly improved in OPG treated mice starting at 28-day post-treatment (P<0.05). Histological assessment demonstrated that OPG gene transfer dramatically protected mice from erosive joint changes compared with LacZ controls (P<0.05), although treatment appeared less effective on the local inflammatory progress. …”
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High Doses of Caffeine during the Peripubertal Period in the Rat Impair the Growth and Function of the Testis by Minji Park, Yuri Choi, Hyeonhae Choi, Ju-Yearn Yim, Jaesook Roh

“…The caffeine-fed animals had smaller and lighter testes than those of the control that were accompanied by negative influences on the histologic parameters of the testes. In addition, stimulated-testosterone ex vivo production was reduced in Leydig cells retrieved from the caffeine-fed animals. …”
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Developing a Novel and Convenient Model for Investigating Sweat Gland Morphogenesis from Epidermal Stem Cells by Tian Hu, Yongde Xu, Bin Yao, Xiaobing Fu, Sha Huang

“…Using this coculture system, morphological alteration, histological features, and specific markers were observed. …”
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FBXO31-mediated ubiquitination of OGT maintains O-GlcNAcylation homeostasis to restrain endometrial malignancy by Na Zhang, Yang Meng, Song Mao, Huiling Ni, Canhua Huang, Licong Shen, Kun Fu, Lu Lv, Chunhong Yu, Piyanat Meekrathok, Chunmei Kuang, Fang Chen, Yu Zhang, Kai Yuan

“…Here we report that O-GlcNAcylation level is positively correlated with EC histologic grade in a Chinese cohort containing 219 tumors, validated in The Cancer Genome Atlas dataset. …”
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Pathogenic KIAA0586/TALPID3 variants are associated with defects in primary and motile cilia by Jacqueline E. Taudien, Diana Bracht, Heike Olbrich, Sebastian Swirski, Fulvio D’Abrusco, Bert Van der Zwaag, Maike Möller, Thomas Lücke, Norbert Teig, Ulrika Lindberg, Kai Wohlgemuth, Julia Wallmeier, Anja Blanque, Christos Gatsogiannis, Sebastian George, Christoph Jüschke, Marta Owczarek-Lipska, Dorothee Veer, Hester Y. Kroes, Enza Maria Valente, G. Christoph Korenke, Heymut Omran, John Neidhardt

“…In two unrelated families, a deep-intronic variant (KIAA0586/TALPID3:c.3990 + 3186G>A) activated a cryptic exon. We performed histological and functional analyses in native and air-liquid interface (ALI) cultured respiratory cells. …”
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Transplanted Endothelial Progenitor Cells Improve Ischemia Muscle Regeneration in Mice by Diffusion Tensor MR Imaging by Xin-Gui Peng, Yingying Bai, Judy R. James, Darya P. Shlapak, Shenghong Ju

“…There was a significant correlation between fiber counts calculated by DTI and survival fibers evaluated by histological section (r=0.873, P<0.01). Our study demonstrated that the time frame for muscle fiber regeneration after EPCs transplantation was significantly shortened in vivo. …”
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Domestication may affect spawning performance of F1 pikeperch (Sander lucioperca) during consecutive captive reproduction by Bahram Falahatkar, Iraj Efatpanah, Eshagh Rasouli Kargar, Mehdi Rahmati, Pascal Fontaine

“…Fingerlings of pikeperch, produced in controlled reproduction from wild fish, were grown in captive conditions to sexual maturity for 2 years in concrete tanks. Histological observations revealed that the fish were in the peripheral nucleoli stage at 20-month old and ready to spawn at 2-year-old (129.3 ± 12.9 g) with an increase in water temperature. …”
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Sequential release of cytokines, lipid mediators and nitric oxide in experimental colitis by A. P. M. van Dijk, Z. J. Keuskamp, J. H. P. Wilson, F. J. Zijlstra

“…The degree of inflammation was scored by a standardized macroscopic and histological examination. Initially, a 60% maximum inflammation score was observed at day 4. …”
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Cancer Stem Cell Marker Endoglin (CD105) Induces Epithelial Mesenchymal Transition (EMT) but Not Metastasis in Clear Cell Renal Cell Carcinoma by Junhui Hu, Wei Guan, Libin Yan, Zhangqun Ye, Lily Wu, Hua Xu

“…Clear cell renal cell carcinoma (ccRCC) is the most common histological subtype of kidney cancer. We previously reported that CD105(+) subpopulation in human ccRCC tumors possesses tumor cell self-renewal and chemoresistance capability. …”
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Benign Multicystic Peritoneal Mesothelioma in a Male Patient with Previous Wilms’ Tumor: A Case Report and Review of the Literature by Gian Luigi Canu, Fabio Medas, Giulio Columbano, Luca Gordini, Luca Saba, Enrico Erdas, Pietro Giorgio Calò

“…The postoperative period was complicated by a peritonitis due to dehiscence of the intestinal anastomosis, which required another operation, and a delayed return of normal bowel function, which was resolved through prokinetic therapy. Through histological examination, a BMPM was diagnosed. At 8 months of follow-up, the patient is free of symptoms. …”
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Galectin-3 Inhibitors Suppress Anoikis Resistance and Invasive Capacity in Thyroid Cancer Cells by Jie-Jen Lee, Yi-Chiung Hsu, Ying-Syuan Li, Shih-Ping Cheng

“…Accumulating evidence suggests that galectin-3 is a histologic marker of thyroid cancer. However, the pharmacological lectin-based approach has not been well studied. …”
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Generational Expression of Muir-Torre Syndrome in a Canadian Family by Kaitlin Alexandra Vanderbeck, R. Gary Sibbald, Nirosha Murugan

“…Recently she presented with two nodular lesions. Histologic examination confirmed these lesions to be sebaceous neoplasms. …”
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Optimum Combination of Insulin-Transferrin-Selenium and Fetal Bovine Serum for Culture of Rabbit Articular Chondrocytes in Three-Dimensional Alginate Scaffolds by Lanlan Zhang, Hong Song, Xiaojun Zhao

“…At designed time point, the Chondrocyte-seeded alginate hydrogels were harvested and evaluated with histological staining, immunohistochemistry, and quantitative gene expression analysis. …”
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Effects of Splenectomy on Spontaneously Chronic Pancreatitis in aly/aly Mice by Heng-Xiao Wang, Shuang-Qin Yi, Jun Li, Hayato Terayama, Munekazu Naito, Shuichi Hirai, Ning Qu, Nozomi Yi, Masahiro Itoh

“…Forty-eight 10-week-old aly/aly mice were divided into two groups for splenectomy and sham operation. Histological and immunohistochemical analyses of the pancreas were performed at the ages of 20, 30, and 40 weeks old after operation, respectively. …”
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Utilization of Cardiac Magnetic Resonance Imaging for Assessing Myocardial Fibrosis in Prognosis Evaluation and Risk Stratification of Patients with Dilated Cardiomyopathy by Xin-Yi Feng, Yu-Cong Zheng, Ying-Xia Yang, Wen-Feng He, Fan Yang, Ling-Li Wang, Han-Feng Yang, Chun-Ping Li, Xiao-Xue Xu, Rui Li

“…Late gadolinium enhancement (LGE) derived from cardiovascular magnetic resonance is the clinical gold standard for evaluating replacement myocardial fibrosis and exhibits high concordance with histological replacement fibrosis. However, because of the absence of normal tissue as a control, the LGE technique often fails to effectively visualize diffuse interstitial fibrosis. …”
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Long-Lasting Follow-Up with Low-Dose Steroid in an 18-Year-Old Male with Rosai–Dorfman Disease by Volkan Karakuş, Yelda Morgül Dere, Dilek Ersil Soysal

“…Lymphadenopathy is the predominant clinical manifestation, but diverse organs can also be affected. Histological features involve S-100+ histiocytes with characteristic nuclear features within the enlarged sinusoids of the lymph nodes. …”
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