Exploring the Anti-Osteoporotic Effects of <i>n</i>-Hexane Fraction from <i>Cotoneaster wilsonii</i> Nakai: Activation of Runx2 and Osteoblast Differentiation In Vivo by Soyeon Hong, Hee Ju Lee, Da Seul Jung, Saruul Erdenebileg, Hoseong Hwang, Hak Cheol Kwon, Jaeyoung Kwon, Gyhye Yoo

“…Biochemical assays and histological analyses focused on the signaling activation of osteoblast differentiation and osteogenic markers, such as ALP, collagen, and osterix. …”
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Alveolar Ridge Preservation Using a Novel Synthetic Grafting Material: A Case with Two-Year Follow-Up by Peter Fairbairn, Minas Leventis, Chas Mangham, Robert Horowitz

“…At reentry for placement of the implant, a bone core biopsy was obtained, and primary implant stability was measured by final seating torque and resonance frequency analysis. Histological analysis revealed pronounced bone regeneration while high levels of primary implant stability were recorded. …”
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Langerhans Cell Histiocytosis of the Cranial Base: Is Low-Dose Radiotherapy Effective? by Andreas Meyer, Michael Stark, Johann H. Karstens, Hans Christiansen, Frank Bruns

“…The diagnosis of LCH was confirmed histologically by biopsy. Diagnostic workup verified the cranial lesion as the sole manifestation of LCH. …”
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Preventive Effect of TU-100 on a Type-2 Model of Colitis in Mice: Possible Involvement of Enhancing Adrenomedullin in Intestinal Epithelial Cells by Atsushi Kaneko, Toru Kono, Naoko Miura, Naoko Tsuchiya, Masahiro Yamamoto

“…Our current aims were to examine whether TU-100 ameliorates a type-2 model colitis that histologically resembles UC and identify the active ingredients. …”
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Application of Metabolomics in Thyroid Cancer Research by Anna Wojakowska, Mykola Chekan, Piotr Widlak, Monika Pietrowska

“…However, in some cases, cytological and histological patterns are inconclusive; hence, classification based on histopathology could be supported by molecular biomarkers, including markers identified with the use of high-throughput “omics” techniques. …”
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Oral Lesions Induced by Chronic Khat Use Consist Essentially of Thickened Hyperkeratinized Epithelium by Ochiba Mohammed Lukandu, Lionel Sang Koech, Paul Ngugi Kiarie

“…This study aimed to describe histological changes induced by chronic khat chewing on the buccal mucosa. …”
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Endoscopic Mucosal Resection Performed Underwater for Nonampullary Duodenal Epithelial Tumor: Evaluation of Feasibility and Safety by Goro Shibukawa, Atsushi Irisawa, Ai Sato, Yoko Abe, Akane Yamabe, Noriyuki Arakawa, Yusuke Takasaki, Takumi Maki, Yoshitsugu Yoshida, Ryo Igarashi, Shogo Yamamoto, Tsunehiko Ikeda, Hiroshi Hojo

“…There were 14 participants, with a total of 16 lesions, who underwent UW-EMR between August 2015 and December 2017. Histological heteromorphism revealed that seven patients had low-grade adenoma, seven had high-grade adenoma, and two had adenocarcinoma. …”
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Large Pyoderma Gangrenosum-Like Ulcers: A Rare Presentation of Granulomatosis with Polyangiitis by Basheer Tashtoush, Roya Memarpour, Yasmin Johnston, Jose Ramirez

“…However, a wide range of clinical and histologic features may be seen. We herein report a case of a previously healthy 52-year-old Caucasian man who presented with multiple progressively enlarging painful ulcers on his face, upper extremities, back, and abdomen over a two-month period. …”
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Hydrogen-Rich Saline Inhibits NLRP3 Inflammasome Activation and Attenuates Experimental Acute Pancreatitis in Mice by Jian-Dong Ren, Jie Ma, Jun Hou, Wen-Jin Xiao, Wei-Hua Jin, Juan Wu, Kai-Hua Fan

“…Therefore, in this study, we evaluated the activation of NLRP3 inflammasome and meanwhile assessed the degree of oxidative stress and inflammatory cascades, as well as the histological alterations in mice suffering from cerulein-induced AP after the treatment of HRS. …”
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Establishment and characterization of a sigmoid colon cancer organoid with spinal metastasis by Jingyao Chen, Jingyao Chen, Shumin Cheng, Liang Gu, Liang Gu, Zhangsen Huang, Zhangsen Huang, Changhua Zhang, Changhua Zhang, Chunhui Sun, Chunhui Sun, Chunhui Sun, Songyao Chen, Songyao Chen

“…The organoid culture maintained the morphological features, histological features, and genomic landscape of the corresponding sigmoid colon cancer cells. …”
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Role of New Functional MRI Techniques in the Diagnosis, Staging, and Followup of Gynecological Cancer: Comparison with PET-CT by Elena Alvarez Moreno, Mar Jimenez de la Peña, Raquel Cano Alonso

“…Both techniques can be used as biomarkers of tumor response and present high accuracy in diagnosis of local recurrence and peritoneal dissemination, with complementary roles depending on histological type, anatomic location and tumoral volume.…”
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Fibrous dysplasia in the alveolar crest of edentulous site and the curettage for future implant placement: a case report by Hao Chen, Yuting Wen, Xueqi Guo, Shiyong Zhao

“…This intervention was followed by histologically confirmed healing and successfully integrated implant placement. …”
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Histopathological Study of Bee Venom with Different Concentrations in Laboratory Mice by Zeyad G. Al-Rikabi, Montaha Abdulkareem Al-Saffar, Huda S. Nassir, Inam B. Falih

“…In conclusion, bee venom administered to groups in different concentrations revealed hepatic and renal complications at histological investigations of hematoxylin and eosin-stained sections of liver and kidney section. …”
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A Review of the Aetiopathogenesis and Clinical and Histopathological Features of Oral Mucosal Melanoma by Liviu Feller, Razia A. G. Khammissa, Johan Lemmer

“…Microscopical examination is essential for diagnosis, and routine histological staining must be supplemented by immunohistochemical studies. …”
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Exposure to nano-polystyrene during pregnancy leads to Alzheimer's disease-related pathological changes in adult offspring by Fengxu Wang, Jin Wang, Na Luo, Yonghua Luo, Zhengnan Gao, Ye Cui, Mengna Jiang, Zhaoping Shen, Jing Xiao, Peng Xue, Xiaoke Wang, Shali Yu, Qiyun Wu, Xinyuan Zhao

“…In contrast with the control group, prenatal PS-NPs exposure obviously decreased brain tissue weight and the organ coefficient (brain weight/body weight) in adult male mice, but it only led to changes in the low-dose group of female mice. Histological examination of the adult offspring brains revealed alterations following exposure to PS-NPs during gestation. …”
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The Angiogenic Potential of DPSCs and SCAPs in an In Vivo Model of Dental Pulp Regeneration by Petra Hilkens, Annelies Bronckaers, Jessica Ratajczak, Pascal Gervois, Esther Wolfs, Ivo Lambrichts

“…After twelve weeks, histological and ultrastructural analysis demonstrated the regeneration of vascularized pulp-like tissue as well as mineralized tissue formation in all stem cell constructs. …”
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The effect of ozone exposure on the release of eicosanoids in guinea-pig BAL fluid in relation to cellular damage and inflammation by H. J. M. Van Hoof, F. J. Zijlstra, H-P. Voss, I. M. Garrelds, J. A. M. A. Dormans, L. Van Bree, A. Bast

“…After the acute exposure an increase in LDH activity was measured and after exposure to 1 ppm ozone for 12 h the exudation of protein and albumin was also enhanced. The histological examinations showed a neutrophilic inflammatory response only after exposure to 1 ppm ozone for 12 h. …”
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Severe Necrotizing Adenovirus Tubulointerstitial Nephritis in a Kidney Transplant Recipient by Ravi Parasuraman, Ping L. Zhang, Dilip Samarapungavan, Leslie Rocher, Alan Koffron

“…We report a case of severe ADVIN with characteristic histological features that includes severe necrotizing granulomatous lesion with widespread tubular basement membrane rupture and hyperchromatic smudgy intranuclear inclusions in the tubular epithelial cells. …”
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Prostate Cancer Incidence and Mortality in Barbados, West Indies by Anselm J. M. Hennis, Ian R. Hambleton, Suh-Yuh Wu, Desiree H.-A. Skeete, Barbara Nemesure, M. Cristina Leske

“…We ascertained all histologically confirmed cases of prostate cancer during the period July 2002 to December 2008 and reviewed each death registration citing prostate cancer over a 14-year period commencing January 1995. …”
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Nociceptive and Neuronal Evaluation of the Sciatic Nerve of Wistar Rats Subjected to Compression Injury and Treated with Resistive Exercise by Juliana Sobral Antunes, Keli Lovison, Jhenifer Karvat, Ana Luiza Peretti, Lizyana Vieira, Guilherme Hideaki Higuchi, Rose Meire Costa Brancalhão, Lucinéia de Fátima Chasko Ribeiro, Gladson Ricardo Flor Bertolini

“…Regarding allodynia, CG obtained values less than EG (p=0.012) and larger than LG and LEG (p<0.001). Histological results showed that CG and EG had normal appearance, as LG and LEG showed up with large amounts of inflammatory infiltration, degeneration and disruption of nerve fibers, and reduction of the myelin sheath; however LEG presented some regenerated fibers. …”
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