High FGF18 expression levels predict poor prognosis in endometrial carcinoma patients and promote tumor growth and metastasis by Zheng-Yao Lei, Jian Wu, Bao-Hua Zhang, Wei Xiang, Min Wang, Bin-bin Li, Ming-Cheng Dai

“…Results High FGF18 expression levels were closely correlated with EC clinicopathological features, such as histological subtype, FIGO stage, depth of myometrial invasion, and tumor size. …”
Get full text

Acute Toxicity and Antioxidant and Antibacterial Activities of Kyllinga polyphylla Willd. ex Kunth, Cyperaceae Family by Van-Ay Nguyen, Thi-Hang Phung, Thi-Diem-Trang Kieu, Trong-Hong-Phuc Nguyen

“…KP extracts did not cause death at a dose of 5000 mg/kg body weight and did not significantly change the biochemical, hematological, as well as histological structures of internal organs in toxicity-tested mice in comparison with the control. …”
Get full text

Recent Advances in Drug-Induced Hypersensitivity Syndrome/Drug Reaction with Eosinophilia and Systemic Symptoms by Hideaki Watanabe

“…Published data has demonstrated that among patients with DIHS/DRESS, 75–95% have leukocytosis, 18.2–90% show atypical lymphocytes, 52–95% have eosinophilia, and 75–100% have hepatic abnormalities. Histologically, eosinophils were observed less frequently than we expected (20%). …”
Get full text

Results of non-interventional observational study of ursodeoxycholic acid in primary biliary cirrhosis by Yelena N. Shirokova, Anna F. Sheptulina

“…The majority (43,2%) of patients had PBC of the histological grade II according to the Ludwig system. …”
Get full text

Carvacrol attenuates N-nitrosodiethylamine induced liver injury in experimental Wistar rats by Balan Rajan, Rajendran Ravikumar, Thandavamoorthy Premkumar, Thiruvengadam Devaki

“…The hoisted activities of Phase I enzymes and inferior activities of Phase II enzymes were observed in DEN-administered animals, whereas Carvacrol treated animals showed improved near normal activity. Histological observations also support the protective role of Carvacrol against DEN induced liver damage. …”
Get full text

Verrucous Papillary Lesions: Dilemmas in Diagnosis and Terminology by Thomas George Kallarakkal, Anand Ramanathan, Rosnah Binti Zain

“…Current understanding of potentially malignant VPLs is perplexing and is primarily attributed to the use of confusing and unsatisfactory terminology. Clinically and histologically oral verrucous hyperplasia, a potentially malignant disorder, resembles oral verrucous carcinoma and may be indistinguishable from one another. …”
Get full text

Integrated Network Pharmacology and Experimental Validation Approach to Investigate the Therapeutic Effects of Capsaicin on Lipopolysaccharide-Induced Acute Lung Injury by Peihui Liu, Jindou Hao, Jie Zhao, Rong Zou, Juan Han, Jia Tian, Wanqu Liu, Hao Wang

“…Additionally, the histological assessment, ELISA, and RT-qPCR were performed to confirm the therapeutic effect and the potential mechanism action involved. …”
Get full text

Premalignant Lesions of the Colon by Rodger C Haggitt

“…Such lesions must be removed in their entirety and examined histologically to exclude the presence of carcinoma. Approximately 51 % of patients with colonic adenomas removed by endoscopic polypectomy will be found to have a carcinoma within the polyp. …”
Get full text

Penile Rehabilitation after Pelvic Cancer Surgery by Fouad Aoun, Alexandre Peltier, Roland van Velthoven

“…The principle of early penile rehabilitation stems from animal studies showing early histological and molecular changes associated with penile corporal hypoxia after cavernous nerve injury. …”
Get full text

A New Case of Spontaneous Regression of Inflammatory Hepatic Pseudotumor by Hichem Jerraya, Slim Jarboui, Hassen Daghmoura, Abdeljelil Zaouche

“…In our cae report here, the analysis of previous history, of clinical, biological and radiological presentation, had permittes us to pose the diagnosis of PTI of the liver and this despite the absence of histological confirmation by percutaneous biopsy.…”
Get full text

A Comparison of Two Anastomotic Techniques in the Jejunum of the Goat by H. A. Al-Timmemi, Karim Al-Jashamy, Mohammed S. Dauod

“…Macroscopic evaluation indicated that the anastomotic line mucosa was abridged better with less local edema in the SSIS group. Histological evaluation in the SSIS group showed almost all parameters such as epithelial recovery and repair of submucosal-mucosal layer demonstrated better healing compared to the HMIS group.…”
Get full text

Atractylenolide III Improves Mitochondrial Function and Protects Against Ulcerative Colitis by Activating AMPK/SIRT1/PGC-1α by Jieru Han, Wenhao Li, Guangyu Shi, Yunlei Huang, Xutao Sun, Na Sun, Deyou Jiang

“…The results showed that in DSS-induced mice, AT III significantly reversed the body weight loss, colon length reduction, disease activity index (DAI) increase, and histological damage. The production of proinflammatory factors and reduction of antioxidants in colitis were suppressed by AT III. …”
Get full text

Evaluation of Acute and Sub-Chronic Toxicity of Lactobacillus rhamnosus GG in Sprague-Dawley Rats by Vedam Venkata Kanthi Vaishnavi, Urmila Banik, Gokul Shankar Sabesan, Arun K. Adhikary, Subramani Parasuraman

“…The animals administered with L. rhamnosus showed no histological changes in the organs such as heart, liver and kidney. …”
Get full text

Antiinflammatory Efficacy of Extracts of Latex of Calotropis procera Against Different Mediators of Inflammation by Soneera Arya, Vijay L. Kumar

“…Both extracts produced about 80%, 40%, and 30% inhibition of inflammation induced by BK, compound 48/80, and serotonin. The histological analysis revealed that the extracts were more potent than PBZ in inhibiting cellular infiltration and subcutaneous oedema induced by carrageenin. …”
Get full text

Clinical and Diagnostic Considerations for Atypical, Adult Onset Presentation of Chronic Recurrent Multifocal Osteomyelitis (CRMO) by Stacey Mahady, Amit Ladani

“…Imaging findings included multiple bony lesions on x-rays, increased uptake in the left side of the pelvis, ileum, proximal sternum, and bilateral medial clavicles on nuclear bone scan. Bone biopsy histologic results of marrow fibrosis and plasma cell infiltrate indicative of chronic inflammation lead to the diagnosis of CRMO. …”
Get full text

Mesenchymal Stem Cells Ameliorate Hyperglycemia in Type I Diabetic Developing Male Rats by Hany N. Yousef, Samia M. Sakr, Sahar A. Sabry

“…MSC therapy in an early stage reversed most of the biochemical, histological, and ultrastructural alterations in the STZ-induced diabetic model and restored the normal cellular population of most acinar cells and islet of Langerhans. …”
Get full text

The Role of the Pathoanatomical Diagnosis «Chronic Gastritis» in the System of Personified Cancer Prevention by A. V. Kononov

“…Molecular classification of gastric cancer is considered from the standpoint of carcinogenesis cascade and WHO 2010 histological classification. New molecular and cellular targets for the preparation of bismuth tripotassium dicitrate and practical steps of its use in the prevention of gastric cancer in chronic inflammation of the mucosa of various etiologies are conceptually described.Conclusion.  …”
Get full text

Comparison of One-Drill Protocol to Sequential Drilling In Vitro and In Vivo by Sihana Rugova, Marcus Abboud

“…In the animal model, a histological analysis revealed a trend favoring shorter drilling protocols, with reduced drilling times and a potential advantage for osseointegration, though the BIC differences were not statistically significant. …”
Get full text

Diagnosis and Treatment of Esophageal Candidiasis: Current Updates by Abdimajid Ahmed Mohamed, Xin-liang Lu, Faycal Awaleh Mounmin

“…This disease is confirmed histologically by taking the biopsy or brushings of yeast and pseudohyphae invading mucosal cells. …”
Get full text

Adult Granulosa Cell Tumor of the Testis: A Case Report with a Review of the Literature by Klaus-Peter Dieckmann, Julia Bertolini, Christian Wülfing

“…Scrotal sonography disclosed a 6 mm hypoechoic intratesticular lesion. Histological examination after orchiectomy revealed a homogeneous and well demarcated neoplasm with monomorphic cells with nuclear grooving and microfollicular formation of the so-called Call-Exner bodies. …”
Get full text