Uncovering the role of tumor cGAS expression in predicting response to PD-1/L1 inhibitors in non-small cell lung cancer by Yuichi Ozawa, Yasuhiro Koh, Ryota Shibaki, Yuhei Harutani, Hiroaki Akamatsu, Atsushi Hayata, Takeya Sugimoto, Yuka Kitamura, Junya Fukuoka, Masanori Nakanishi, Nobuyuki Yamamoto

“…Unexpectedly, patients with high cGAS (H-score ≥ 220) demonstrated significantly shorter progression-free survival (PFS) of PD-1/L1 inhibitors when the PD-L1 TPS was high (median PFS: 143 days vs. not reached; p = 0.028); PFS at 18 months was 7% and 53% in the high and low cGAS groups, respectively while STING expression did not impact PFS. …”
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Hubungan Kejadian Anemia dengan Penyakit Ginjal Kronik pada Pasien yang Dirawat di Bagian Ilmu Penyakit Dalam RSUP dr M Djamil Padang Tahun 2010. by Rahmat Hidayat, Syaiful Azmi, Dian Pertiwi3 Pertiwi

“…</p><p><strong>Kata kunci:</strong> anemia, penyakit ginjal kronik, laju filtrasi glomerulus</p><p> </p><p><strong><em>Abstract</em></strong></p><p><em>Anemia is one of the major problems in patients with chronic kidney disease. High and low glomerular filtration rate affect the incidence of anemia in chronic kidney disease. …”
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Carbon sequestration in different urban vegetation types in Southern Finland by L. Thölix, L. Backman, M. Havu, M. Havu, E. Karvinen, J. Soininen, J. Trémeau, O. Nevalainen, J. Ahongshangbam, L. Järvi, L. Järvi, L. Kulmala

“…All models indicated notable year-to-year differences in annual sequestration rates, but since the same factors, such as temperature and soil moisture, affect processes both assimilating and releasing carbon, connecting the years of high or low carbon sequestration to single meteorological means failed. …”
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An FPGA-Based SiNW-FET Biosensing System for Real-Time Viral Detection: Hardware Amplification and 1D CNN for Adaptive Noise Reduction by Ahmed Hadded, Mossaad Ben Ayed, Shaya A. Alshaya

“…The CNN model, implemented on an Altera DE2 FPGA, enables high-throughput, low-latency signal processing, making the system viable for real-time applications. …”
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Antibiotic knowledge and influencing factors among residents in China: a cross-sectional survey by Sixian DU, Yaqing LIU, Xiaoxu YIN, Haoran NIU, Feng JIANG, Liwen GONG

“…Respondents were divided into high and low scoring groups based on their average scores. …”
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Vitamin D binding protein genetic isoforms, serum vitamin D, and cancer risk in the Prostate, Lung, Colorectal, and Ovarian (PLCO) Cancer Screening Trial. by Stephanie J Weinstein, Dominick Parisi, Alison M Mondul, Tracy M Layne, Jiaqi Huang, Rachael Z Stolzenberg-Solomon, Regina G Ziegler, Mark P Purdue, Wen-Yi Huang, Christian C Abnet, Neal D Freedman, Kai Yu, Demetrius Albanes

“…For most cancers, the GC genotype did not modify the risk associations for 25(OH)D; e.g., the OR for high vs. low vitamin D quintile was 1.09 (0.89-1.33) for overall cancer risk among individuals with the Gc1-1 isoform and 1.04 (0.83-1.31) among those with either the Gc1-2 or Gc2-2 isoforms. …”
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Global prevalence, treatment and outcome of tuberculosis and COVID-19 coinfection: a systematic review and meta-analysis (from November 2019 to March 2021) by Qiang Sun, Hui Li, Jie Zhao, Xiaolin Wei, Quan Wang, Shasha Guo, Quanfang Dong, Ning Xu

“…Nineteen countries reported coinfected patients, including high and low TB prevalence countries. The only study revealing prevalence rate came from West Cape Province, South Africa (people aged above 20 years, 0.04% until 1 June 2020 and 0.06% until 9 June 2020). …”
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Identification of cancer cell-intrinsic biomarkers associated with tumor progression and characterization of SFTA3 as a tumor suppressor in lung adenocarcinomas by Yu Zhao, Chengcheng Zhou, Ling Zuo, Haoming Yan, Yuhan Gu, Hong Liu, Guiping Yu, Xiaorong Zhou

“…The model effectively stratified patients into high- and low-risk categories, revealing that low-risk patients experienced superior clinical outcomes, exhibited an immunologically hot tumor microenvironment (TME), and had a greater probability of responding to immunotherapy. …”
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Correlation between immune signature and high‐density lipoprotein cholesterol level in stage II/III colorectal cancer by Yun Wang, Xiao‐qiang Sun, Hao‐cheng Lin, De‐shen Wang, Zhi‐qiang Wang, Qiong Shao, Feng‐hua Wang, Shu‐mei Yan, Jie‐ying Liang, Zhao‐lei Zeng, Huai‐qiang Ju, Rui‐hua Xu, Yu‐hong Li

“…Fifty‐five pairs of tumor tissues were selected according to the variation in HDL‐C levels (high or low) and the matched characterizes (ages, T stage, and N stage). …”
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Integrative analysis of cuproptosis-related lncRNAs: Unveiling prognostic significance, immune microenvironment, and copper-induced mechanisms in prostate cancer by Haitao Zhong, Yiming Lai, Wenhao Ouyang, Yunfang Yu, Yongxin Wu, Xinxin He, Lexiang Zeng, Xueen Qiu, Peixian Chen, Lingfeng Li, Jie Zhou, Tianlong Luo, Hai Huang

“…Survival analysis suggested that patients could be divided into high- and low-risk groups according to model scores and that there was a significant difference in disease-free survival (DFS) (P < 0.01). …”
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Soil phosphorus mobilization as affected by long-term organic fertilization in a tropical Regosol by Kalline De Almeida Alves Carneiro, Tancredo Augusto Feitosa De Souza, Gislaine Dos Santos Nascimento, Vânia Da Silva Fraga, Bruno de Oliveira Dias

“…We estimated the contents of Fe and Al oxides with high and low crystallinity. The miscible displacement technique was used to simulate P leaching in soil columns, and the leached P was quantified by colorimetry. …”
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Laser Applications in Metal Orthodontic Bracket Debonding: A Systematic Review by Patryk Woś, Sylwia Kiryk, Tomasz Dyl, Jan Kiryk, Tomasz Horodniczy, Magdalena Szablińska, Magdalena Aleksandra Dubowik, Wojciech Dobrzyński, Marcin Mikulewicz, Jacek Matys, Maciej Dobrzyński

“…Four publications were assessed as high quality (low risk of bias), and another four as moderate quality (average risk of bias). …”
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High anti-Müllerian hormone level as a predictor of poor pregnancy outcomes in women with polycystic ovary syndrome undergoing in vitro fertilization/intracytoplasmic sperm injecti... by Fei Zhao, Duo Wen, Lin Zeng, Ruiqi Wang, Dingran Wang, Huiyu Xu, Rong Li, Hongbin Chi

“…Anti-Müllerian hormone was associated with increased miscarriage rate in the average and high anti-Müllerian hormone groups compared with that in the low anti-Müllerian hormone group (average vs. low: odds ratio: 1.592, 95% confidence interval: 1.017–2.490); high vs. low: odds ratio: 2.045, 95% confidence interval: 1.152–3.633). …”
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Effects of two kinds of vestibular function training on reducing motion sickness in college students by Linyao Shi, Jing Zhao, Jiamei Lu, Chuanxia Cao, Qikun Zhang, Chuanjing Qiu, Zhanguo Jin, Shengguang Yan, Shengguang Yan, Shengguang Yan

“…When the two groups were stratified into high and low-susceptibility subgroups, the low-susceptibility subgroup of the electric rotating chair group had lower Graybiel scores and diastolic blood pressures than the low-susceptibility visual-motion cage rotating chair subgroup, whereas in the high susceptibility subgroup, LF, rMSSD, and pNN50 were significantly higher in the visual-motion cage rotating chair group than in the electric rotating chair group.DiscussionThis study compared the effects of two types of vestibular function training on Graybiel scores and heart rate variability (HRV). we found that seven days of training with both the electric rotating chair and the visual-motion cage rotating chair relieved MS symptoms and enhanced sympathetic regulation. …”
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Unveiling and validating biomarkers related to the IL-10 family in chronic sinusitis with nasal polyps: insights from transcriptomics and single-cell RNA sequencing analysis by Xinghong Liu, Yi Peng, Ling Guo, Weilan Xiong, Weijiang Liao, Jiangang Fan

“…Candidate genes were identified by intersecting differentially expressed genes (DEGs) between the CRSwNP and control groups (DEGsall) with those between the high- and low-score groups within the CRSwNP cohort (DEGsNP). …”
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A satellite-based analysis of semi-direct effects of biomass burning aerosols on fog and low-cloud dissipation in the Namib Desert by A. Mass, A. Mass, H. Andersen, H. Andersen, J. Cermak, J. Cermak, P. Formenti, E. Pauli, E. Pauli, J. Quinting

“…The statistical model is able to reproduce the observed differences in FLC dissipation time between high- and low-BBA days and attributes these differences mainly to differences in circulation, boundary layer moisture and near-surface air temperature along the coastline. …”
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Microplastic contamination in different tissues of commercial fish in estuary area by N.D. Takarina, O.M. Chuan, A. Adiwibowo, F.N.A. Jeffery, N.Z.A.B.N.M. Zamri, M.A. Adidharma

“…In contrast, in the tissues of Mugil cephalus and Scatophagus argus, microplastics were found in the following order of abundance from high to low: muscle, gastrointestinal tract, gill. The muscle of Mugil cephalus contained the highest microplastic concentration (28.71 particles per gram wet weight), while the lowest was recorded in the muscle of Eleutheronema tetradactylum (3.42 particles per gram wet weight). …”
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Positive end-expiratory pressure and risk of postoperative pulmonary complications in patients living at high altitudes and undergoing surgery at low altitudes: a single-centre, re... by Zhuoning Li, Kaixi Shang, Zongjing Xia, Xiaoli Ye, Chongcong Gong

“…There were no differences in the incidence of PPCs between the high and low PEEP groups (relative risk (RR) 0.913; 95% CI 0.716 to 1.165; p=0.465). …”
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Long-Term Analysis of Recurrence Beyond Milan Criteria Following Ablation of Solitary Early-Stage Hepatocellular Carcinoma &le;3 cm in Potentially Transplantable Patients: A Over 1... by Chen S, Qi H, Tan H, Cao F, Xie L, Huang T, Wu Y, Wen C, Wang Y, Shen L, Fan W

“…Notably, RBM was a superior predictive indicator for OS compared to recurrence (P< 0.05).Conclusion: When using ablation as a bridge to liver transplantation for solitary HBV-related early HCC (≤ 3 cm), it is crucial first to identify key preoperative features, including high CRP, low PLT, cirrhosis, and older age. Keywords: hepatocellular carcinoma, hepatitis B virus, ablation techniques, transplantable liver transplantation, recurrence beyond the Milan criteria…”
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Determinants of fertility in timed artificial insemination programs in beef cattle: predictive ability and risk factors from almost 2 million data points by R.E.F. Assis, F. Baldi, L.B. Temp, R. Ungerfeld, M.F. de Sá Filho

“…(P/AI) was affected by Order of service (1st TAI > resynchronizations), body condition class (BCS) (high > medium > low), female genetic group [Bos taurus and crossbreds > Bos indicus], breeding season (reduction of the P/AI every year), female category [Non-lactating multiparous > Suckled multiparous > Suckled primiparous > Nulliparous heifers], period of year (July-September, October-December and January-March > April-June) and climatic region as well as the interactions between Order of service and female category, BCS class and female genetic group (impact of BCS: Bos taurus or crossbreed animals > Bos indicus), BCS and female category (impact of BC:S Suckling > non-Suckling categories), female category and time of female availability, female category and female genetic group, female category and climatic region, and climatic region and period of the year. …”
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