Quantum chemical study of molecular properties of small branched-chain amino acids in water by Roman Boča, Žofia Rádiková, Juraj Štofko, Beata Vranovičová, Cyril Rajnák

“…A mutual comparison of these structural isomers including γ-aminobutyric acid (GABA) shows high degree of similarity in molecular descriptors. …”
Get full text

Synthesis, In vitro antimicrobial activity, and In silico bioinformatical approach of xanthone-fatty acid esters against Staphylococcus aureus, Escherichia coli, and Candida albica... by Yehezkiel Steven Kurniawan, Ervan Yudha, Jumina, Harno Dwi Pranowo, Eti Nurwening Sholikhah

“…Microbial infection is gaining attention nowadays due to a high number of active cases and mortality rate. Because of that, research in finding new antimicrobial agents is urgently needed. …”
Get full text

A proposal to measure the resilience of the Andalusian Commnunity Social Services by Elena Ferri-Fuentevilla, Ana Vallejo-Andrada, Aleix Morilla-Luchena, Rocío Muñoz Moreno

“…Critical indicators to assess social service resilience were put forward, in line with the research conducted by Kruk et al. who propose a resilience index for healthcare. …”
Get full text

Loss of Myh14 Increases Susceptibility to Noise-Induced Hearing Loss in CBA/CaJ Mice by Xiaolong Fu, Linqing Zhang, Yecheng Jin, Xiaoyang Sun, Aizhen Zhang, Zongzhuang Wen, Yichen Zhou, Ming Xia, Jiangang Gao

“…In the present study, we used CRISPR/Cas9 technology to establish a Myh14 knockout mice line in CBA/CaJ background (now referred to as Myh14−/− mice) and clarify the role of MYH14 in the cochlea and NIHL. …”
Get full text

Millimetre-Wave Metamaterial-Based Sensor for Characterisation of Cooking Oils by Suhail Asghar Qureshi, Zuhairiah Zainal Abidin, Adel Yahya Isa Ashyap, Huda A. Majid, Muhammad Ramlee Kamarudin, Ma Yue, Mohd Syis Zulkipli, Jamel Nebhen

“…The sensor’s novelty is the operation at millimetre-wave frequencies that offers a high shift in the transmission coefficient while operating at 30 GHz. …”
Get full text

Delta-opioid receptor signaling alleviates neuropathology and cognitive impairment in the mouse model of Alzheimer’s disease by regulating microglia homeostasis and inhibiting HMGB... by Yuan Xu, Naiyuan Shao, Feng Zhi, Ronghua Chen, Yilin Yang, Jiahui Li, Ying Xia, Ya Peng

“…Methods We compared the delta-opioid receptor (DOR)- and mu-opioid receptor (MOR)-mediated effects on AD-associated cognitive deficits, pathologies, neuroinflammations, cell death using transgenic APP/PS1 mouse model and BV2 cell line at behavioral, molecular, and cellular levels. …”
Get full text

Cancer stem cell populations are resistant to 5-aminolevulinic acid-photodynamic therapy (5-ALA-PDT) by Chantel P. J. Rice, Vipin Shankar Chelakkot, Noah T. Conohan, Kensuke Hirasawa

“…Moreover, we found that the CSC population was enriched in 5-ALA-PDT-resistant cell lines compared to the parental cell line. Our results indicate that CSCs are not sensitive to 5-ALA-PDT, which may contribute to establishment of 5-ALA-PDT resistance.…”
Get full text

Exposure of Mesenchymal Stem Cells to an Alzheimer’s Disease Environment Enhances Therapeutic Effects by Sang Eon Park, Hyeong Seop Kim, Soo Jin Kwon, Min-Jeong Kim, Suk-joo Choi, Soo-young Oh, Gyu Ha Ryu, Hong Bae Jeon, Duk L. Na, Jong Wook Chang

“…We focused on the role of primed MSCs (human Wharton’s jelly-derived mesenchymal stem cells (WJ-MSCs) exposed to an AD cell line via a coculture system) in reducing the levels of Aβ and inhibiting cell death. …”
Get full text

Potentials of transanal endoscopic surgery at early rectal cancer by Yu. A. Shelygin, S. V. Chernyshov, L. P. Orlova, E. G. Rybakov

“…The average distance from the lower pole of tumor to outer edge of anal canal and to dentate line was 7,1±1,7 cm (4,0–9,0 cm) and 4,8±1,9 cm (1,5–7,0 cm) respectively. …”
Get full text

Diagnosis and Treatment of Elderly and Senile Chronic Constipation: an Expert Consensus by V. T. Ivashkin, M. G. Mnatsakanyan, V. S. Ostapenko, А. P. Pogromov, V. M. Nekoval, E. A. Poluectova, Yu. V. Kotovskaya, N. K. Runikhina, N. V. Sharashkina, P. V. Tsarkov, N. O. Tkacheva, Yu. N. Belenkov

“…The treatment tactics in chronic constipation is cause-conditioned and should account for the patient’s history and therapy line, overall clinical condition, cognitive status and functional activity level. …”
Get full text

Comparative analysis of the efficacy and safety of fixed-dose combinations versus their individual components for open-angle glaucoma by Z.M. Nagornova, A.V. Kuroyedov, A.V. Seleznev

“…Among them, fixed-dose combinations are of special importance which are considered as first-line agents for some patients (i.e., with advanced glaucoma or high intraocular pressure). …”
Get full text

Identification of a Novel Anticancer Oligopeptide from Perilla frutescens (L.) Britt. and Its Enhanced Anticancer Effect by Targeted Nanoparticles In Vitro by Dong-Liang He, Ri-Ya Jin, Hui-Zhen Li, Qing-Ye Liu, Zhi-Jun Zhang

“…The oligopeptides were isolated from enzymatic hydrolysates of Perilla seed crude protein by using ultrafiltration, gel filtration chromatography, and reversed-phase high-performance liquid chromatography (RP-HPLC). …”
Get full text

Efficiency of <i>in vitro</i> culture techniques applied to soybean (<i>Glycine max (L.) Merr.</i>) accessions from the VIR collection by E. S. Korshikova, K. M. Ershova, Yu. A. Moksheninova, Yu. V. Ukhatova

“…This research trend is in line with Presidential Decree No. 680 “Concerning the development of genetic technologies in the Russian Federation”. …”
Get full text

The Effect of Poverty on Rural Livelihoods in Uganda: A Case Study of Katooke Sub-County Kyenjojo District. by Mukabazaire, Mary

“…The study findings were presented and analyzed in line with specific objectives. The respondents who accounted for 17(18%) of the respondents who participated in the study reported that the high population growth rate has been one of the main causes of poverty in the Katoke Sub-county. …”
Get full text

Local Anesthesia Versus Saddle Block for Open Hemorrhoidectomy: Cost-Analysis From a Randomized, Double Blind Controlled Trial. by Sikakulya, Franck Katembo, Ssebuufu, Robinson, Okedi, Xaviour Francis, Baluku, Moris, Lule, Herman, Kiyaka, Sonye Magugu, Muhumuza, Joshua, Selamo, Fabrice Molen, Bassara, Godefroy Nyenke, Waziri, Musa Abbas, Kithinji, Stephen Mbae, Mugisho, Munyerenkana Leocadie, Byamungu, Pahari Kagenderezo, Munihire, Jeannot Baanitse, Vahwere, Bienfait Mumbere, Kiswezi, Ahmed, Kyamanywa, Patrick

“…Background Despite the benefits attributed to the use of local anesthesia (LA) for open hemorrhoidectomy (OH) in developed countries, this technique is still not considered as the first-line technique in low-income countries such as Uganda; therefore, we aimed to compare the cost of OH under LA versus Saddle block among patients with 3rd or 4th-degree hemorrhoids. …”
Get full text

2009 Canadian Association of Gastroenterology Educational Needs Assessment Report by Alaa Rostom, Sandra Daniels

“…The two most popular educational formats were ‘Lectures/presentations streamed to computer/podcasts’ and ‘A CAG educational portal to on-line presentations, self-assessments and maintenance of certification (MainCert) point tracking’.…”
Get full text

Refractory human cytomegalovirus infection without evidence of genetic resistance in the UL-54 and UL-97 genes in a pediatric hematopoietic stem cell transplant recipient: a case r... by Alejandra Pando-Caciano, Ketty Adid Escudero-Ramirez, Jackeline Carol Rodríguez-Torres, Holger Maita-Malpartida, Holger Maita-Malpartida

“…Furthermore, this case highlights the importance of using highly sensitive genetic tools to detect mutations associated with virus resistance in a broader range of the viral genome.…”
Get full text

Anti-influenza effects of Aloe vera gel on MDCK cells: protective efficacy against ultraviolet-C exposure and analysis of biochemical characteristics and microbial activities by Rasha A. Al-Eisa, Rokayya Sami, Ruqaiah I. Bedaiwi, Roqayah H. Kadi, Suzan A. Abushal, Doaa Mahmoud Johari, Afnan M. Alnajeebi, Reham M. Algheshairy, Abeer A. Abu-Zaid, Sami A. Al-Dhumri

“…The main objective of the current study was to examine the anti-influenza effects of Aloe vera gel on the Madin–Darby Canine Kidney (MDCK) cell line, as well as its protective efficacy against ultraviolet-C exposure, by studying its biochemical characterization and microbial activities. …”
Get full text

New dimension in vortex electro-magnetic wave transmission with orbital angular momentum by Chao ZHANG, Yuanhe WANG

“…Consequence:In order to illustrate the application scope and the outstanding advantages utilized by quantum OAM electromagnetic waves and statistical OAM Beams, this paper classifies the typical OAM transmission systems into four regions based on channel capacity.From the high channel capacity to the low channel capacity, Region A belongs to the quantum OAM transmission system with the new dimension of OAM, using vortex microwave photon to convey information, and the corresponding capacity bound can be enhanced to surpass the traditional multi-antenna MIMO capacity bound;Regions B,C and D belong to the statistical OAM vortex beams,which do not own new dimensions in MIMO transmission but have outstanding performance in the Line-of-Sight (LoS) channel. …”
Get full text

Metabolic Phenotyping of Adipose-Derived Stem Cells Reveals a Unique Signature and Intrinsic Differences between Fat Pads by Camille Lefevre, Baptiste Panthu, Danielle Naville, Sylvie Guibert, Claudie Pinteur, Bénédicte Elena-Herrmann, Hubert Vidal, Gilles J. P. Rautureau, Anne Mey

“…Metabolism is central to stem cell fate decision in line with environmental changes. In this study, we performed high-resolution nuclear magnetic resonance (NMR) metabolomic analyses of ASC culture supernatants in order to characterize their metabolic phenotype in culture. …”
Get full text