Second-line drug-resistant TB and associated risk factors in Karakalpakstan, Uzbekistan by S. Moe, I. Azamat, S. Allamuratova, M. Oluya, A. Khristusev, M.L. Rekart, K. Mamitova, G. Bidwell, C. Gomez-Restrepo, B. Kalmuratov, Z. Tigay, N. Parpieva, K. Safaev, N. Sitali, D. Gomez, A. Mikhail, A. Sinha

“…METHODS: A retrospective study was conducted using extensive programmatic data from 2019 to 2023 in Uzbekistan. We assessed second-line drug-resistant TB (SLDR-TB) rates using phenotypic drug susceptibility testing (pDST). …”
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Establishment and characterization of a new mouse gastric carcinoma cell line, MCC by Yushen Wang, Xianju Li, Yi Wang, Jun Qin

“…Genomic and proteomic analyses were conducted to characterize the molecular features of the cell lines. This cell line demonstrated a 100% success rate in forming subcutaneous tumors in BALB/c mice. …”
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An Optimized Liquid Chromatography–Mass Spectrometry Method for Ganglioside Analysis in Cell Lines by Akeem Sanni, Andrew I. Bennett, Yifan Huang, Isabella Gidi, Moyinoluwa Adeniyi, Judith Nwaiwu, Min H. Kang, Michelle E. Keyel, ChongFeng Gao, C. Patrick Reynolds, Brian Haab, Yehia Mechref

“…Ceramide, Hex1Cer, GM1, and GM3 were highly abundant in CRL-1620, PSN1, and MDA-MB-231BR, respectively. …”
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High-level mosaicism for 45,X in 45,X/46,XX at amniocentesis in a pregnancy with positive non-invasive prenatal testing for Turner syndrome, postnatal decrease of the 45,X cell line and a favorable fetal outcome by Chih-Ping Chen

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Establishment and characterization of three gemcitabine-resistant human intrahepatic cholangiocarcinoma cell lines by Jiandong Li, Yanxin Hu, Jiayao Zhang, Weiguang Zhang, Jianhua Yu, Baochun Lu

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Assessment of drought resistance in sorghum CMS lines based on various sterility sources by O. P. Kibalnik, T. V. Larina, O. B. Kameneva, D. S. Semin

“…Global climate changes have recently led to a more frequent occurrence of adverse factors and a decrease in the productivity of major crops. Sorghum is a highly drought-resistant crop that can tolerate long-term soil and air droughts with much lower harvest losses than wheat or barley. …”
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Case report: PD-L1-targeted high-affinity natural killer cells and IL-15 superagonist N-803-based therapy extend overall survival of advanced metastatic pancreatic cancer patients by Tara Seery, Lennie Sender, Omid Jafari, Frank Jones, Patricia Spilman, Sandeep B. Reddy, Patrick Soon-Shiong

“…BackgroundMetastatic pancreatic cancer (mPC) is an aggressive form of cancer with a poor prognosis and few therapeutic options after failure of the second-line treatment. Induction of immunogenic cell death (ICD) by use of relatively low-dose chemo- or radiation therapy, enhancement of immune responses by the IL-15 superagonist N-803 (Anktiva®), and targeting of programmed death receptor ligand 1 (PD-L1)-expressing cells may offer a therapeutic approach to refractory mPC with the potential to increase overall survival (OS).MethodsFrom late 2019 to 2021, single-patient Investigational New Drug (spIND) protocols for five mPC patients were designed and approved that generally comprised combined Abraxane (nab-paclitaxel) and gemcitabine therapy with experimental therapeutics N-803, PD-L1-targeted high-affinity natural killer (PD-L1 t-haNK) cells, and aldoxorubicin, a serum albumin-binding doxorubicin prodrug. …”
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Peering into the Black Box: Forward Modeling of the Uncertainty Budget of High-resolution Spectroscopy of Exoplanet Atmospheres by Arjun B. Savel, Megan Bedell, Eliza M.-R. Kempton, Peter C. B. Smith, Jacob L. Bean, Lily L. Zhao, Kaze W. K. Wong, Jorge A. Sanchez, Michael R. Line

“…Ground-based high-resolution cross-correlation spectroscopy (HRCCS; R  ≳ 15,000) is a powerful complement to space-based studies of exoplanet atmospheres. …”
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Search for Vector Charmonium(-Like) States in the e+e-→ηJ/ψ Line Shape by Jielei Zhang, Rumin Wang

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Date recognition based on multi feature extraction by Min WANG, Jia WU, Shuo SUN, Sheng LI, Kang WANG

“…Drug production date and expiration date are important indicators to measure the safety and effectiveness of drugs.The production date and validity period of liquid drugs in vertical bags are printed with numbers of 0～9.The recognition of the drug date of the hospital needs to meet the requirements of high speed and accuracy.The conventional template matching method and neural network recognition method have large amount of calculation and complex training.A drug date recognition method was proposed based on multi feature extraction.The combination of vertical line feature and three features for fine feature extraction of different digital characters has advantages of small amount of calculation and fast recognition speed.Compared with the recognition method of single extracted feature, it can effectively distinguish 10 different numbers, especially suitable for numbers of similar shape.It can provide patients with safe drug use guarantee, improve the management mode of the medical staff, improve the work efficiency, so as to improve the level of the pharmaceutical service of the hospital.…”
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Vertical Line Extension Decisions in a Competitive Market with Consumers’ Need for Product Uniqueness by Jie Wang, Qin Su, Canyou Wang

“…In this paper, we take consumers’ unique preferences into account to examine how firms make decisions on vertical line extensions with introducing a customized product. …”
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A cost-effective and miniaturized SPN deployment strategy for group customer dedicated lines by Cheng CHEN, Han WANG, Shuchong NAN

“…With the change of networking mode in the evolution of 5G network, SPN is faced with the limitations of ubiquitous coverage, which leads to the long access distance of the passenger dedicated line customers.Based on the operator's benefit-oriented construction idea, in order to solve the network benefit problem in the process of further deepening SPN coverage.Three sink deployment strategies were proposed for different scenarios, taking the empirical value cost of typical configurations as an example.By building a simulation environment, Gaussian mixture model was used to simulate the distribution characteristics of group customers, and the relationship between the total number of customers, the number of sinking SPN devices and customer coverage in sparse, common and dense scenarios were analyzed, and the network benefits of different sinking strategies were tested.The simulation results show that strategy 3 only faces the area coverage with high sinking efficiency when the total number of customers is 600, and the maximum coverage rate can only reach 55.27%.However, with the increase of customer points, the maximum coverage rate of strategy 3 can reach 82.71%, which has obvious coverage advantages.At the same time, the average number of sunk equipment can cover the highest number of customers, realizing the high coverage ability under the condition of ensuring high efficiency.…”
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Dynamic response of aerodynamic flutter of blooie line during gas drilling in mountain areas by Dianchen Liu, Peng Yang, Ke Deng, Shijie Tian, Hai Yan, Hongtao Li

“…As a result, aerodynamic flutter will occur when high-speed gas flow enters the blooie line, which threatens drilling safety. …”
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Preparation and Protective Performance of High-Reflection and High-Thermal Insulation Laser Protection Coatings by LI Shuwen, WU Lingfeng, YANG Guanjun, CHEN Lin

“…Laser weapons have entered the actual combat application stage， and the research on anti-laser protection for air and space weapons is becoming increasingly urgent.Prolonged high-energy laser irradiation leads to problems such as reduced metal reflectance，mass loss of ablated layer of the ablative layer and insufficient heat insulation toughness.Based on this，a composite laser protection strategy based on the principles of reflection and heat insulation was proposed.In this study， by adjusting spraying power， spraying distance and other parameters， supersonic flame spraying technology and plasma spraying technology were used to prepare NiCoCrAlTaY bond coating and yttria-stabilized zirconia(YSZ) top coating double-layer coatings， to explore the influence of surface roughness and porosity on reflectivity， and to investigate the laser protection performance of the coatings.Results showed that the larger the spraying power or spraying distance， the more obvious the layer effect， and the more cross-sectional pores were observed in the coating.The surface roughness of the coating decreased first and then increased with the increase in spraying distance.When the secondary reflection structure was removed， the coating surface had Ra＝1.8 μm.When Ra＝0.5 μm， the wedge-shaped structure of the coating increased the reflectivity by about 2.4%compared to that of the coating when Ra＝1.8 μm.It was pointed out that the layered pores were key to the high-reflection wedge structure， the spherical voids were the laser absorption points，and the process parameter of 14.7%porosity (39 kW，100 mm) was the best.In the laser ablation experiment，with the increase in laser power density， the cracks in the coating gradually increased until holes were ablated.The line ablation rate increased approximately in a parabolic manner.With low laser power density (<3 800 W/cm2)， the surface structure changed slightly； as the power increased， the surface cracks increased and deepened， and the petal-like structure in the recondensing zone increased.With high laser power density (>8 050 W/cm2)， partial peeling and ablation of the coating surface caused the coating to fail.…”
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Experimental analysis of flashover characteristics for overhead power lines based on the lightning fractal model by ZHAN Jintao, YANG Tianyi, GUO Jun

“…Both the simulation experiments and the simulation results indicate that the points with high flashover probability are concentrated near the transmission line, and the overall flashover space presents a parabolic shape, conforming to the flashover law. …”
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Assessment of Groundnut Elite Lines under Drought Conditions and Selection of Tolerance Associated Traits by Achirou Bacharou Falke, Falalou Hamidou, Oumarou Halilou, Abdou Harou

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Research of On-line Detection System of End-face Run-out of Synchronizer Gear Set by Shen Kai, Liu Feifei, Meng Dejiao

“…The measuring instrument has high precision and fast speed,and can be applied to the on-line detection of the synchronizer tooth set,which provides a new detection method and idea.…”
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UHF Metamaterial Absorber with Small-Size Unit Cell by Combining Fractal and Coupling Lines by Shicheng Fan, Yaoliang Song

“…We present a perfect UHF metamaterial absorber by combining coupling lines and fractal lines with a very small unit cell. …”
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Study on Seismic Response and Damping Measures of Surrounding Rock and Secondary Lining of Deep Tunnel by Baoli Tang, Yongqiang Ren

“…Tunnel construction is gradually developing to areas with high in situ stress; the deeper the tunnel construction, the more intense the earthquake disturbance. …”
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Evaluation of an in situ QAM‐based Power Line Communication system for lithium‐ion batteries by Mahyar J. Koshkouei, Erik Kampert, Andrew D. Moore, Matthew D. Higgins

“…Abstract Power Line Communication (PLC) is used to transmit high‐fidelity data on internal cell characteristics from within instrumented cells to an external Battery Management System (BMS). …”
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