Development and model test of dynamic loading system in mine goaf site for high-speed railway subgrade by Lianwei REN, Liang LI, Ziqiang WANG, Youfeng ZOU, Zhilin DUN, Shuren WANG

“…With the rapid advancement of the high-speed railway network, it is inevitable that some key lines will cross the mininggoaf site. …”
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In vitro high-content screening reveals miR-429 as a protective molecule in photoreceptor degeneration by Georgios Petrogiannakis, Irene Guadagnino, Santiago Negueruela, Martina Di Guida, Elena Marrocco, Mariateresa Pizzo, Annalaura Torella, Mariateresa Zanobio, Marianthi Karali, Diego Luis Medina, Sabrina Carrella, Sandro Banfi

“…Given their ability to simultaneously modulate multiple molecular pathways, miRNAs represent promising therapeutic tools for disorders with high genetic heterogeneity, such as IRDs. In the present study, we performed high-content imaging (HCI) screening to assess the impact of miRNA overexpression on a photoreceptor cell line undergoing light-induced degeneration. …”
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Improving panicle blast resistance and fragrance in a high-quality japonica rice variety through breeding by Junhua Ye, Junhua Ye, Kai Wang, Yi Wang, Zhipeng Zhao, Ying Yan, Hang Yang, Lixia Zhang, Lixia Zhang, Zejun Hu, Zejun Hu, Zhenying Shi, Dapeng Sun, Jianjiang Bai, Liming Cao, Liming Cao, Shujun Wu, Shujun Wu

“…IntroductionHuruan1212 (HR1212) is well-regarded for its superior eating and cooking quality in the lower reaches of the Yangtze River in China. Still, its high susceptibility to rice panicle blast and lack of fragrance have limited its further spread and utilization. …”
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Hormonal-Receptors-Positive and HER2-Negative Patients with Metastatic Breast Cancer Treated with First-Line Palbociclib and Hormonal Therapy: Impact of First-Cycle Neutropenia and... by Khaled Abd Elaziz Ahmed Elnaghi, Hosam Ali Alghanmi, Shereef Ahmed Elsamany, Fathia Almarzoki, Mohamed Elsafty, Mohammad Jaffal

“…We recruited 150 patients who received first-line palbociclib with hormonal therapy. 86% of patients developed 1st cycle neutropenia which was more common in patients with high Ki67. …”
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Evaluation of the merit of ethanolic extract of Annona reticulata as an anti-cancer agent in human colon cancer cell lines (HCT-116) [version 2; peer review: 2 approved, 1 not appr... by Sri Pragnya Cheruku, Krishnananda Prabhu, Akshatha G Nayak, Vijetha Shenoy Belle, Vanishree Rao, Pooja Prakash Rao, Nitesh Kumar

“…This study was aimed to explore the anti-proliferative and anti-migratory activity of various fractions of Annona reticulata ethanolic leaf extract on human colon cancer cell lines (HCT-116) and to explore the potential molecular targets from the most potent plant extract fraction. …”
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High-Fat Mouse Model to Explore the Relationship between Abnormal Lipid Metabolism and Enolase in Pancreatic Cancer by Lin Qin, Kai Sun, Li Shi, Yushan Xu, Rongping Zhang

“…We constructed a high-lipid model of pancreatic carcinoma cell lines and knockdown and overexpressed enolase in pancreatic carcinoma cell lines and investigated whether high lipid regulates epithelial-mesenchymal transition (EMT) by upregulating enolase (ENO), thereby promoting the cells of pancreatic carcinoma to invade and migrate. …”
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Stochastic Risk Assessment with a Lagrangian Solution for the Optimal Cost Allocation in High-Speed Rail Networks by Jing Zuo, Jianwu Dang, Min Lyu

“…Inspired by the theoretical risk evaluation methods in the complex network, three major factors, including the local effects, global effects, and component self-effects are considered in the process of assessing the impact on the network components (nodes or lines). By introducing the component failure occurrence probability, which is considered to be an exponential function changing with the component maintenance costs, a feasible stochastic risk assessment model of the HSRNs together with the component impact assessment is proposed that can better unify the impact assessment of both the high-speed rail stations and railways. …”
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Rice Breeding for High Grain Yield under Drought: A Strategic Solution to a Complex Problem by Shalabh Dixit, Anshuman Singh, Arvind Kumar

“…These QTLs are being pyramided together to develop drought-tolerant versions of popular drought-susceptible varieties. The near-isogenic lines (NILs) developed can replace the popular, high-yielding but drought-susceptible varieties in rainfed areas prone to drought. …”
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New approach of recycling vanadium‐bearing slags as a binder in high‐alumina refractory castables application by Mathilda Derensy, Thomas Zanin, Jan‐Felix Bleck, Thorsten Tonnesen, Jesus Gonzalez‐Julian

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Decoding the mannose receptor-mAb interaction: the importance of high-mannose N-glycans and glycan-pairing by Julia Baumeister, Maximilian Meudt, Sybille Ebert, Frank Rosenau, Boris Mizaikoff, Michaela Blech, Kristina M. J. Aertker, Fabian Higel

“…The high-mannose N-glycan content of mAbs can be influenced during the cell culture process by factors such as cell lines, process conditions, and media. …”
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Fixed start method for repetitive project scheduling with simulated annealing by Francisco Moreno, Eric Forcael, Francisco Orozco, Felipe Baesler, Duzgun Agdas

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Generation and characterization of novel induced pluripotent stem cell (iPSC) lines derived from three symptomatic carriers of a pathogenic MYH11 variant and two non-carrier relati... by Aria Atash, Maarten Jan Cramer, Barend Mees, Pieter A. Doevendans, Joost P.G. Sluijter, Francesca Stillitano

“…The phenotype has proven highly variable with reduced penetrance. Here, we report human induced pluripotent stem cell (iPSC) lines, generated from peripheral blood mononuclear cells (PBMCs) of three variant carriers and two non-carrying family members. …”
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Emplois contemporains des adverbes d’intensité SO et TOTALLY by Lionel Dufaye, Lucie Gournay

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Short-term endoscopic alterations of early gastric cancer after successful eradication of Helicobacter pylori by Xiaohan Yan, Jingze Li, Zehua Zhang, Bensong Duan, Meidong Xu, Qinwei Xu

“…The endoscopic photographs were evaluated for the endoscopic features and confidence level of demarcation line (DL), invasion depth, and histopathological classification by three highly experienced endoscopists. …”
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Development and characterization of a line with substitution of chromosome 4B of wheat <i>Triticum aestivum</i> L. on chromosome 4H^<i>mar</i> of wild barley <i>Hordeum... by L. A. Pershina, N. V. Trubacheeva, V. K. Shumny, E. D. Badaeva

“…Cytogenetic stability and fertility of line 4Hmar(4B) indicated a high compensation ability of barley 4Hmar for wheat chromosome 4B and confirmed their homeology.…”
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Unified Compact Formulas of Output Characteristics for External Hydraulic Gear-motors by Liu Ping, Li Yulong, Hou Xinyu, Zhang Lihua

“…The results show that through the interval of the output characteristic meshing-line, the output speed and torque curve can be directly obtained from the speed and torque curve of meshing tooth-profile; under the symmetrical relief-groove type, the average output speed is the smallest, the average torque is the biggest, and the ripple coefficients of the output speed and torque are the smallest; the offset range of the relief-groove and the range of the output speed and torque regulating are larger under small backlash type than large backlash type; with small backlash and symmetrical relief-groove type, the average output speed is smaller, the average output torque is larger, and the ripple coefficient of the output speed and torque is smaller; the torque-ripple coefficient of the gear-motor is completely consistent with the flow-ripple coefficient of the gear-pump; the torque-ripple coefficient is slightly less than the speed-ripple coefficient, and can be approximately equal under the condition of large tooth-number; when high-speed is pursued, the type combination of large backlash and relief groove limit-offset shall be selected; with the pursuit of large torque or high output ripple-quality, the type combination of small backlash and symmetrical relief-groove shall be selected, etc. …”
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Temperatures and treeline elevation in the Sierra Nevada de Mérida of the Venezuelan Andes by Vicente Marcano, Rafael Navarro-González, Christopher P. McKay

“…At the tree line, the annual mean temperature at 10 cm depth was 6.66°C with an annual maximum temperature of 13°C and an annual minimum temperature of 1.4°C; the lowest maximum temperature for any day of the year was 6°C, so though there is not continuous growth, every day of the year the temperature gets high enough that some growth is possible. …”
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Evaluation of ground-based methods for monitoring neotectonic processes at geodynamic sites by B. Lysko, T. Hutsul

“…The authors used different methods, in particular geodetic measurements, which ensure high accuracy and reliability of the results; geophysical methods that help to detect subsurface structures and processes; and remote sensing of the Earth, which provides large-scale monitoring and analysis of the dynamics of neotectonic phenomena. …”
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First evidence of sinter and travertine in Cameroon: fault reactivation and geothermal implications by Tchouatcha, Milan Stafford, Kouske, Arnaud Patrice, Tamfuh, Primus Azinwi, Préat, Alain, Toyama, René, Feumba, Roger, Tiokeng Ngounfack, Vannelle, Madjingain, Vivant, Konglim, Yaya Berinyuy, Tchameni, Rigobert

“…The Laopanga hot spring deposits along the “Cameroon Volcanic Line” (CVL) are distinctive in being both siliceous sinter and travertine, made up of immature amorphous silica and mainly calcite, and associated with detrital deposits such as claystone, sandstone and conglomerate. …”
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Haploid biotechnology as a tool for creating a selection material for sugar beets by E. O. Kolesnikova, E. I. Donskikh, R. V. Berdnikov

“…The article considers the stages of obtaining the H and DH lines of Beta vulgaris L., as well as the main stages of biotechnological production of homozygous breeding material of this culture. …”
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