Rhopalurus junceus scorpion venom induces G2/M cell cycle arrest and apoptotic cell death in human non-small lung cancer cell lines by Alexis Díaz-García, Ángel Garrido, Jenny Laura Ruiz-Fuentes, Tamara Hermosilla, Diego Varela

“…Methods: This study evaluated the effect of Rhopalurus junceus scorpion venom on cell viability, in non-cancerous (MRC-5, lung; CHO-K1, ovary) and NSCLC (A549; NCI-H460) cell lines. The effects on cell cycle, apoptosis, and cell signaling-related proteins were determined by flow cytometry and WB. …”
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Evaluation of change in emergency care knowledge and skills among front-line healthcare providers in Ukraine with the Basic Emergency Care course: a pretest/post-test study by Sean M Kivlehan, Amy Allen, Olha Viun, Dmitry A Makarov, Daniel Schnorr, Sonny Patel, Sergii A Ryzhenko, Phuong Pham, Timothy B Erickson

“…The most common positive feedback themes were high-quality teaching and useful skill sessions. …”
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In vitro and in vivo investigations of selected varieties of Areca catechu L - Phytochemical analysis, antiulcer, and wound healing activity by R. Deveswaran, D.J. Madhu Kumar, V. Madhavan, Soma Chaki, Misbah Khan, Govind R. Kadambi, B.V. Basavaraj, J. Anbu

“…Methods: Selected varieties of arecanut were subjected to phytochemical analysis, GC-MS, HPTLC analysis, cell line studies using human oral and intestinal cell lines, wound healing, and anti-ulcer activity studies. …”
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Comparison of plasma start-up with high Z and low Z first wall in WEST by C. Guillemaut, K. Afonin, G. Bodner, J. Bucalossi, Y. Corre, P. Devynck, A. Diallo, M. Diez, N. Fedorczak, A. Gallo, B. Guillermin, V. Lapleigne, R. Lunsford, P. Maget, J. Morales, Ph. Moreau, the WEST Team, the EUROfusion Tokamak Exploitation Team

“…Until 2019, WEST featured a full high Z first wall with all limiters exposing only W surfaces to the plasma. …”
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A network comparison on efficacy and safety profiling of PD-1/PD-L1 inhibitors in first-line treatment of advanced non-small cell lung cancer by Jie Fu, Jie Fu, Yi-Dan Yan, Xu Wan, Xiao-Fan Sun, Xiao-Fan Sun, Xiu-Mei Ma, Ying-Jie Su

“…ObjectivePD-1/PD-L1 inhibitors are novel immunotherapeutic agents that have been approved for first-line treatment in advanced non-small cell lung cancer (NSCLC). …”
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Modern economic prerequisites of development of the knowledge-intensive and high technology productions in Russia taking into account world tendencies by E. Belokonov

“…Relevance of development of the knowledge-intensive and high technology productions in Russia is proved and the structure of the Russian and world export of high-technology products is analyzed and competitive line items of Russia in high-technology sectors are determined. …”
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Research on formant estimation algorithm for high order optimal LPC root value screening by Hua LONG, Shumeng SU

“…Results: As can be seen from the algorithm structure, the speech signal is preprocessed, in which the low frequency information is reweighted to reduce the interference of fundamental frequency to formant detection.And the high frequency information is enhanced to increase the amplitude distinction of the third formant in the high spectrum line. …”
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Optimized for routine: highly sensitive fluorescent Telomeric Repeat Amplification Protocol (f-TRAP) by Silke Fähnrich, Anne Wedemann, Laura Steenpass, Wilhelm Gerhard Dirks

“…The present f-TRAP protocol, optimized for routine use, enables fast ad hoc application for single measurements up to a high throughput of mass samples using a triplicate approach of different lysate concentrations. …”
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Simultaneous Optimization of Train Timetabling and Platforming Problems for High-Speed Multiline Railway Network by Qin Zhang, Xiaoning Zhu, Li Wang, Shuai Wang

“…With the construction of high-speed railways, an increasing number of interactions between trains on multiple lines have led to resource assignment difficulties at hub stations. …”
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Energy Consumption Analysis of High-Speed Trains under Real Vehicle Test Conditions by Qing Zhang, Hongjun Yu, Xin Su, Yao Li

“…The energy consumption of CRH2 and CRH380A EMUs on flat and sloping lines was compared. Moreover, the start-up energy consumption of CRH2 and CRH380A EMUs was compared. …”
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Unsteady Seepage Analysis of Extra-high Core-wall Rockfill Dam During Impoundment by YANG Huigang, LIU Detan, SHANG Yongxi, WANG Junfeng, XU Liqun, HUANG Zhangxin

“…The water level of an extra-high core-wall rockfill dam rises rapidly during the impoundment period.To ensure the seepage stability of key parts such as the core wall,this study determines the calculation conditions according to the actual monitoring data.Based on the unstable saturated-unsaturated seepage theory,the finite element method is applied to calculate the unsteady seepage field of the dam.The calculation results show that the anti-seepage effect of the core wall is good during impoundment.The equipotential lines in the dam body are concentrated on the upstream side surface of the core wall,and the maximum seepage gradient reaches 11.52.The value exceeds the average failure gradient of the core wall in the field test but does not reach the allowable seepage gradient under the protection of the filter layer.Therefore,the seepage stability meets the requirements.The calculation results can provide a reference for the subsequent impoundment of this project and other similar projects.…”
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Highly attenuating tracer fibers for fiber orientation determination in short-fiber-reinforced plastics by Mike Kornely, Marc Kreutzbruck

“…  Due to their high specific stiffness and strength by low production costs short fiber reinforced plastics (sFRP) replace increasingly common materials like steel or aluminum in technical devices. …”
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A data envelopment analysis approach for evaluating high-speed freight transportation efficiency by Paulo Chenrrim, Susana Relvas

“…This study addresses the need for support tools to assess the potential of rail freight transport on high-speed lines. Our motivation stems from the fact that this is still an under-explored topic and the importance it can have for the efficiency of the transport and logistics systems. …”
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Autonomous inverse encoding guides 4D nanoprinting for highly programmable shape morphing by Shuaiqi Ren, Zhiang Zhang, Ruokun He, Jiahao Fan, Guangming Wang, Hesheng Wang, Bing Han, Yong-Lai Zhang, Zhuo-Chen Ma

“…Highly programmable shape morphing of 4D-printed micro/nanostructures is urgently desired for applications in robotics and intelligent systems. …”
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Large-scale high uniform optoelectronic synapses array for artificial visual neural network by Fanqing Zhang, Chunyang Li, Zhicheng Chen, Haiqiu Tan, Zhongyi Li, Chengzhai Lv, Shuai Xiao, Lining Wu, Jing Zhao

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High-precision laser monitoring system with enhanced non-uniform scanning for railway safety by Yingying Yang, Cheng Wang, Xiaoqi Liu, Yu Liu, Weier Lu, Zhonglin Zhu, Hongye Yan, Guotang Zhao, Xuechun Lin

“…With China leading the world in high-speed rail mileage, ensuring railway security is paramount. …”
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Chemical Fingerprints of M Dwarfs: High-resolution Spectroscopy on 31 M Dwarfs with SPIRou by Farbod Jahandar, René Doyon, Étienne Artigau, Neil J. Cook, Charles Cadieux, Jean-François Donati, Nicolas B. Cowan, Ryan Cloutier, Stefan Pelletier, Alan Alves-Brito, Jorge H. C. Martins, Hsien Shang, Andrés Carmona

“…Taking the inherent uncertainties into account, we infer the T _eff values of our targets and find an excellent agreement with previous optical and near-infrared studies. Our high-resolution chemical analysis examines hundreds of absorption lines using χ ^2 minimization using PHOENIX-ACES stellar atmosphere models. …”
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Amplitude estimating algorithm for single channel mixing signals by RUI Guo-sheng 1, XU Bin 2, ZHANG Song2

“…Aimed at non-cooperative communication situations an amplitude estimating question for single channel MSK mixing signals with the same modulating parameters was studied.Based on the derivation of cyclic spectrum for MSK mixture,amplitudes of mixing signals were estimated by searching high-intensity spectral lines along cyclic frequency axis at zero frequency.The envelop of leakage spectrum introduced by fast cyclic spectrum calculation was applied to eliminate the illegibility of spectral line selection.The envelop values of leakage spectrum located at high-intensity spec-tral lines were used to correct the corresponding amplitudes of cyclic spectrum in order to improve estimating accuracy.Simulation results show its good performance for mixing signals without large power difference when the SNR is greater than ?…”
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Research on the privacy-preserving point-in-polygon protocol by Jing ZHANG, Shou-shan LUO, Yi-xian YANG, Yang XIN

“…First, an blivious point-line protocol was designed by extending the traditional point-line protocol, making the use of 1-out-n oblivious transfer and the geometric properties of the vector. …”
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Exploring the exoproteome of the parasitic nematode Anisakis simplex (s. s.) and its impact on the human host – an in vitro cross-talk proteomic approach by Robert Stryiński, Robert Stryiński, Ewa Fiedorowicz, Jesús Mateos, Aneta Andronowska, Elżbieta Łopieńska-Biernat, Mónica Carrera

“…In addition, a cross-talk proteomic approach was used to identify differentially regulated proteins (DRPs) in the proteome of the human intestinal epithelial cell line (Caco-2) co-cultured with L3 larvae of A. simplex (s. s.) or directly exposed to two concentrations (low or high) of Anis-EVs. …”
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