Exosomes Regulate the Transformation of Cancer Cells in Cancer Stem Cell Homeostasis by Jiasheng Xu, Kaili Liao, Weimin Zhou

“…However, a highly dynamic equilibrium was found between cancer stem cells and cancer cells, and this indicates that cancer stem cells are no more special target and blocking the transformation of cancer stem cells and cancer cells seem to be a more significant therapy strategy. …”
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Autofluorescence Imaging in the Long-Term Follow-Up of Scleral Buckling Surgery for Retinal Detachment by Panagiotis Salvanos, Helgi D. Björnsson, Valeria Vitelli, Ragnheiður Bragadόttir, Morten C. Moe, Tor P. Utheim

“…Buckle tightening produced alternating hyper-/hypofluorescent streaks, and demarcation lines showed a persistent rugged hyperfluorescent signal. …”
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Zein patterns as effective markers of valuable agronomic traits in maize by V. V. Sidorova, A. V. Konarev, Yu. A. Kerv

“…Specific examples show the effectiveness of using zein markers in the development of new inbred lines and improvement of the existing ones. On the examples of such agronomic traits as early maturity, explosiveness, and waxiness of maize grain, the possibility of controlling the “inclusion” of these traits in the breeding material with the help of zein markers has been demonstrated. …”
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Reconstruction of the Tibial Stump After Fibulectomy by Bezsmertnyi YO, Veremii OA, Shevchuk VI, Bezsmertnyi OY

“…The technique of the operation is described in detail, including petal decortication, two oblique corticotomies of the tibia, formation of bone and periosteum fragments, distraction. The result is a highly functional stump with the possibility of using end support and full prosthetics. …”
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Invasive Salmonella Typhimurium ST313 with naturally attenuated flagellin elicits reduced inflammation and replicates within macrophages. by Girish Ramachandran, Darren J Perkins, Patrick J Schmidlein, Mohan E Tulapurkar, Sharon M Tennant

“…Here, we show that strains of the ST313 genotype are phagocytosed more efficiently and are highly resistant to killing by macrophage cell lines and primary mouse and human macrophages compared to ST19 strains. …”
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The role of TASK-1 and TRPV1 channels in the male reproductive system by Dawon Kang, Eun-A Ko

“…The mammalian testis is a highly organized organ essential for male reproduction. …”
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Big Archive-Assisted Ensemble of Many-Objective Evolutionary Algorithms by Wen Zhong, Jian Xiong, Anping Lin, Lining Xing, Feilong Chen, Yingwu Chen

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GNG2 inhibits brain metastases from colorectal cancer via PI3K/AKT/mTOR signaling pathway by Chenhua Luo, ZhiMing Xiao, WenLong Yang

“…Abstract G-protein gamma subunit 2 (GNG2) plays a vital role in various cellular processes, yet its specific function in colorectal cancer (CRC), particularly in highly invasive cases and brain metastasis, remains unclear. …”
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Targeting the EZH2-PPAR Axis Is a Potential Therapeutic Pathway for Pancreatic Cancer by Jilong Hu, Zhinan Zheng, Jia Lei, Yuxin Cao, Qiyun Li, Zhi Zheng, Chuanjun Chen

“…Enhancer of zeste homolog 2 (EZH2) is abnormally highly expressed in pancreatic cancer (PC). However, it is not ideal to treat PC by inhibiting EZH2. …”
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An Assay System for Plate-based Detection of Endogenous Peptide:N-glycanase/NGLY1 Activity Using A Fluorescence-based Probe by Hiroto Hirayama, Tadashi Suzuki

“…Cytosolic peptide: N-glycanase (PNGase/NGLY1 in mammals), an amidase classified under EC:3.5.1.52, is a highly conserved enzyme across eukaryotes that catalyzes the removal of N-glycans from glycoproteins, converting N-glycosylated asparagine residues into aspartic acid. …”
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Tissue-specific resistance and susceptibility to the tomato brown rugose fruit virus (ToBRFV) conferred by Solanum pennellii loci by Edan Rochsar, Shai Torgeman, Kfir Bandel, Amnon Koren, Chen Klap, Aviv Dombrovsky, Dani Zamir

“…This work employed a new introgression population derived from Solanum pennellii (LA5240), a wild tomato native to Peru, composed of 1,900 genotyped backcross inbred lines (BILs_BC2S6) in the tomato inbreds LEA and TOP cultivated genetic backgrounds. …”
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Targeting Interleukin-4 Receptor Alpha by Hybrid Peptide for Novel Biliary Tract Cancer Therapy by Kahori Seto, Junichi Shoda, Tomohisa Horibe, Eiji Warabi, Masayuki Kohno, Toru Yanagawa, Hiroki Bukawa, Yasuni Nakanuma, Koji Kawakami

“…It is known that the interleukin-4 receptor α (IL-4Rα) is highly expressed on the surface of various human solid tumors. …”
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A Novel Bimodal Imaging Agent Targeting HER2 Molecule of Breast Cancer by Wei Lv, Yamei Shen, Hengli Yang, Rui Yang, Wenbin Cai, Jian Zhang, Lijun Yuan, Yunyou Duan, Li Zhang

“…IR783-NBs-Affibody was able to automatically accumulate on BT474 cells with a highly increased targeting rate of 85.4% compared with previous NBs-Affibody of 26.6%, while Affibody-guided HER2 binding was only found in HER2-positive cell lines (BT474 and T-47D). …”
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Integrative analysis of miRNA expression data reveals a minimal signature for tumour cells classification by Sabrina Napoletano, David Dannhauser, Paolo Antonio Netti, Filippo Causa

“…Our results demonstrate a highly significant differentiation of cancer types, achieving 100 % classification accuracy with minimal training time using a streamlined miRNA signature. …”
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Giant Hall Waves Launched by Superconducting Phase Transition in Pulsars by Ashley Bransgrove, Yuri Levin, Andrei M. Beloborodov

“…The transition to type-II superconductivity is associated with the bunching of magnetic field lines into discrete superconducting flux tubes which possess enormous tension. …”
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Self-healable and pH-responsive spermidine/ferrous ion complexed hydrogel Co-loaded with CA inhibitor and glucose oxidase for combined cancer immunotherapy through triple ferroptos... by Tianqi Nie, Yifei Fang, Ruhe Zhang, Yishui Cai, Xiaobo Wang, Yuenong Jiao, Jun Wu

“…Investigation on cancer cell lines (MOC-1) demonstrated ACZ/GOx@SPM-HA Gel may induce cellular oxidative stress and mitochondrial dysfunction through disrupting the cellular homeostasis. …”
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The Therapeutic Effect of Cytokine-Induced Killer Cells on Pancreatic Cancer Enhanced by Dendritic Cells Pulsed with K-Ras Mutant Peptide by Guang Tan, Xin Zhang, Hongbo Feng, Haifeng Luo, Zhongyu Wang

“…This study is to investigate the role of the CIKs cocultured with K-ras-DCs in killing of pancreatic cancer cell lines, PANC-1 (K-ras+) and SW1990 (K-ras−). Methods. …”
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D-loop mutations in mitochondrial DNA are a risk factor for chemotherapy resistance in esophageal cancer by Takashi Harino, Koji Tanaka, Daisuke Motooka, Yasunori Masuike, Tsuyoshi Takahashi, Kotaro Yamashita, Takuro Saito, Kazuyoshi Yamamoto, Tomoki Makino, Yukinori Kurokawa, Kiyokazu Nakajima, Hidetoshi Eguchi, Yuichiro Doki

“…Abstract Esophageal cancer is a highly aggressive disease, and acquired resistance to chemotherapy remains a significant hurdle in its treatment. mtDNA, crucial for cellular energy production, is prone to mutations at a higher rate than nuclear DNA. …”
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PROLIFERATION AND APOPTOSIS IN RAT MODELS OF ORAL SQUAMOUS CELL CARCINOMA INDUCED BY CAPSAICIN EXTRACT NANOPARTICLE GEL by Pratiwi Nur Widyaningsih, Fitri Aniowati, Cantika Nadrotan Naim, Nova Dwi Anggraeni

“…Background: Oral Squamous Cell Carcinoma (OSCC) is highly invasive neoplasm of oral epithelial tissue that is moderately differentiated and tends to metastasize rapidly. …”
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Localization of the quantitative trait loci related to lodging resistance in spring bread wheat (<i>Triticum aestivum</i> L.) by I. N. Leonova, E. V. Ageeva

“…Phenotypic screening of 97 spring varieties and breeding lines was carried out in the field conditions of the West Siberian region during 2017–2019. …”
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