Selected Abstracts of the 20th International Workshop on Neonatology and Pediatrics; Cagliari (Italy); October 23-26, 2024 by --- Various Authors

“…Itova (Ruse, Bulgaria) ABS 14. LYSOZYME IS HIGHLY EXPRESSED IN MATERNAL MILK STEM/PROGENITOR CELLS • G. …”
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Enhancement of anti‐sarcoma immunity by NK cells engineered with mRNA for expression of a EphA2‐targeted CAR by Pui Yeng Lam, Natacha Omer, Josh K. M. Wong, Cui Tu, Louisa Alim, Gustavo R. Rossi, Maria Victorova, Hannah Tompkins, Cheng‐Yu Lin, Ahmed M. Mehdi, Amos Choo, Melissa R. Elliott, Elaina Coleborn, Jane Sun, Timothy Mercer, Orazio Vittorio, Lachlan J. Dobson, Alexander D. McLellan, Andrew Brooks, Zewen Kelvin Tuong, Seth W. Cheetham, Wayne Nicholls, Fernando Souza‐Fonseca‐Guimaraes

“…These cancers share common challenges, including high rates of metastasis, recurrence or treatment resistance, leading to a 5‐year survival rate of approximately 20% for patients with advanced disease stages. …”
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Comparative Ethics of Modern Payment Models by Jacob Riegler

“…The volume-based incentive of fee-for-service is misaligned with patient care, while capitation is a relatively neutral and highly modifiable model. Value-based payments offer a unique benefit in improving patient agency and have a larger benefit of cost control. …”
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La gestion de l’eau à Bibracte (Saône-et-Loire), avant et après la Conquête romaine by Laetitia Borau

“…The stone-built sewer was 1,70 m high and 0,75 m wide. It evacuated the water from the basin and drained the entire quarter. …”
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Anther transcriptomes in cold-tolerant rice cultivars tend to show insensitive responses by Koichi Yamamori, Seiya Ishiguro, Kei Ogasawara, Kayyis Muayadah Lubba, Kaien Fujino, Kazumitsu Onishi, Yutaka Sato, Yuji Kishima

“…When examining the overall expression patterns in anthers at low temperature, the cold-tolerant lines tended to have relatively few highly expressed genes, and the expression levels of ribosome-related genes tended to be lower in cold-tolerant lines than in cold-sensitive lines. …”
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lncRNA HOTTIP Recruits EZH2 to Inhibit PTEN Expression and Participates in IM Resistance in Chronic Myeloid Leukemia by Jing Liu, Lin Yang, Xiaojun Liu, Lu Liu, Menghan Liu, Xuefeng Feng, Jianmin Luo

“…We confirmed that HOTTIP and EZH2 are highly expressed in IM-resistant patients and IM-resistant CML cell lines. …”
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Stability of a Rock Tunnel Passing through Talus-Like Formations: A Case Study in Southwestern China by Shaoqiang Zhang, Wenqiang Li, Jiashan Tan, Bokuan Li, Xiaochang Li, Shuaifeng Wang, Zixin Zhang

“…The in situ monitoring contents included the surrounding rock pressure on the primary lining, the primary lining deformation, and the stress of steel arches. …”
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Color Dependence on Thickness in Topaz Crystal from Brazil by Waldemar Bonventi Jr, Sadao Isotani, Antonio Roberto Pereira Albuquerque

“…The decomposition revealed several lines, whose assignment was made considering studies in spodumene and beryl crystals and highly accurate quantum mechanical calculations. …”
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Characterization of Genetic Diversity to Ecological Stripe Rust Resistance in Bread Wheat (Triticum aestivum L.) by Khan Mueen Alam, Iqbal Rashid

“…Traits under study like plant height, chlorophyll content index, grain per spike, thousand grain weight, grain filling period, peduncle length, and spike length had positive relation as depicted by correlation analysis. Lines 16, 22, 37, 27 and 51 were far away from other lines thus showed that these were highly diverse in respect to studied parameters.…”
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The Use of Trichostatin A during Pluripotent Stem Cell Generation Does Not Affect MHC Expression Level by Sara Farahi, Sara Hosseini, Hossein Ghanbarian, Seyed Mahmoud Hashemi, Mohammad Salehi, Samaneh Hosseini

“…Established PSC lines were characterized by alkaline phosphatase assay (ALP) and immunocytochemistry. …”
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Interspecific incompatibility in wide hybridization of plants and ways to overcome by L. A. Pershina, N. V. Trubacheeva

“…Postzygotic incompatibility may be associated with a highly pronounced genetic and epigenetic variability induced by wide crossings. …”
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Tumoral Prostate Shows Different Expression Pattern of Somatostatin Receptor 2 (SSTR2) and Phosphotyrosine Phosphatase SHP-1 (PTPN6) According to Tumor Progression by Ariel Ernesto Cariaga-Martinez, María Angelica Lorenzati, Mario Alejandro Riera, Marisa Angelica Cubilla, Andrés De La Rossa, Ernesto Martín Giorgio, María Mercedes Tiscornia, Esteban Mariano Gimenez, María Eugenia Rojas, Bárbara Julieta Chaneton, Dora Isabel Rodríguez, Pedro Darío Zapata

“…Many studies on SHP-1 revealed that the expression of this protein was diminished or abolished in several of the cancer cell lines and tissues examined. However, it is necessary to confront the cell lines data with real situation in cancer cases. …”
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An Objective Study of Anatomic Shifts in Intracranial Hypotension Using Four Anatomic Planes by Shamar J. Young, Ronald G. Quisling, Sharatchandra Bidari, Tina S. Sanghvi

“…This project aims to demonstrate that central incisural herniation is highly effective in helping to make this diagnosis. …”
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Precise intracellular uptake and endosomal release of diverse functional mRNA payloads via glutathione-responsive nanogels by Rupali Dabas, Naveenan Navaratnam, Haruki Iino, Saidbakhrom Saidjalolov, Stefan Matile, David Carling, David S. Rueda, Nazila Kamaly

“…We present a novel, highly customizable glutathione-responsive nanogel (NG) platform for efficient mRNA delivery with precise mRNA payload release control. …”
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PRAF2 as a novel biomarker for breast cancer with machine learning and experimentation validation by Zheng Wang, Zilin Bi, Hongguang Bo, Junyi Xu, Rui Sha, Zhaocai Yin, Changsheng Yu, Yufa Xu, Xiaomeng Shi, Wenbo Song, Bin Chen, Yabing Wang, Qian Zhang, Jianping Chen

“…Results PRAF2 was highly expressed in various cancers, including BC, and in most BC cell lines. …”
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Gasdermin D regulates the activation of EGFR in colorectal cancer by Ying Li, Jiayao Chen, Huijun Liang, Qindan Du, Jingjie Shen, Xiaoying Wang

“…Exogenous addition of Gefitinib was used to evaluate the effect of GSDMD on autophosphorylation of EGFR at the Tyr1068 site. Results GSDMD was highly expressed in clinical CRC tissues and human-derived CRC cell lines. …”
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New bispecific antibodies in diffuse large B-cell lymphoma by Adrian G. Minson, Michael J. Dickinson

“… The CD20xCD3 T-cell-engaging bispecific antibodies are a highly active new treatment option for patients with relapsed or refractory diffuse large B-cell lymphoma (DLBCL). …”
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The BES1/BZR1 transcriptional factor SlBES2 regulates photosynthetic apparatus in tomato fruit by Ming Huang, Wenjing Liu, Deding Su, Ghassen Abid, Baowen Huang, Zhengguo Li

“…Down-regulation of SlBES2 resulted in fruits showing paler fruit than wild type at MG stage, in contrast, SlBES2-overexpressing tomato lines bore deeper green fruits. Notably, chlorophyll content and number of thylakoids per chloroplast in fruit was substantially increased in SlBES2-overexpressing lines, while markedly decreased in SlBES2-suppressing lines. …”
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Legal and Safety Aspects of the Application of Automated and Autonomous Vehicles in the Republic of Croatia by Melita Milenković, Davor Sumpor, Sandro Tokić

“…The stages of road liability for traffic accidents were also investigated, with recommendations of strict (default) liability of manufacturers for fully autonomous vehicles as well as presumed liability of all road traffic participants for highly automated vehicles. The safety and traffic benefits of possible infrastructure upgrades for highly automated and fully autonomous vehicles were discussed, mostly in the segment of dedicated lines.…”
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Near-Infrared Optical Imaging of Ovarian Cancer Xenografts with Novel α3-Integrin Binding Peptide “OA02” by Olulanu H. Aina, Jan Marik, Regina Gandour-Edwards, Kit S. Lam

“…Through screening of random one-bead one-compound (OBOC) libraries, we previously identified cyclic peptides with the cDGXGXXc motif that bind to α3 integrin subunit on ovarian adenocarcinoma cell lines ES-2, SKOV-3, and CaOV-3. We subsequently synthesized two secondary libraries based on this motif and identified new peptides that bound with a higher affinity to these cell lines. …”
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