A prognostic signature of Glutathione metabolism-associated long non-coding RNAs for lung adenocarcinoma with immune microenvironment insights by Junxi Hu, Junxi Hu, Shuyu Tian, Shuyu Tian, Qingwen Liu, Qingwen Liu, Jiaqi Hou, Jiaqi Hou, Jun wu, Jun wu, Xiaolin Wang, Xiaolin Wang, Yusheng Shu, Yusheng Shu

“…High-risk patients showed increased tumor mutation burden (TMB) and stemness, emphasizing the potential of personalized immunotherapy to improve survival outcomes.…”
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Lactoferrin Modulates Radiation Response Under Hypoxic Conditions, Possibly Through the Regulation of ROS Production in a Cell Type-Specific Manner by Daitoku Murakami, Takahiro Fukazawa, Michihito Kyo, Mutsumi Miyauchi, Shigehiro Ono, Tomonao Aikawa, Nobuyuki Hirohashi, Keiji Tanimoto

“…In this study, we focused on the molecular mechanisms of LF functions in cells under hypoxic conditions. High-dose LF treatment showed cytotoxic activity in a variety of cells, including both non-cancer and cancer cells. …”
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Autism common variants associated with white matter alterations at birth: cross-sectional fixel-based analyses of 221 European term-born neonates from the developing human connecto... by Hai Le, Alexandra F. Bonthrone, Alena Uus, Daphna Fenchel, Alexandra Lautarescu, Konstantina Dimitrakopoulou, A. David Edwards, Joseph V. Hajnal, Serena J. Counsell, Lucilio Cordero-Grande, Daan Christiaens, Dafnis Batalle, Maximilian Pietsch, Anthony N. Price, Hamel Patel, Charles Curtis, Harriet Cullen, Maria Deprez, Jacques-Donald Tournier

“…Abstract Increasing lines of evidence suggest white matter (WM) structural changes associated with autism can be detected in the first year of life. …”
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Efficacy and Safety of CART Cell Therapy in Aggressive B‐Cell Lymphomas Involving the Gastrointestinal Tract by Lixia Ma, Yimeng Dou, Rui Liu, Teng Xu, Fan Yang, Peihao Zheng, Shaomei Feng, Yuelu Guo, Hui Shi, Fei Xue, Biping Deng, Xiaoyan Ke, Kai Hu

“…ABSTRACT Objective Currently, chimeric antigen receptor T‐cell (CART) therapy represents a highly effective approach for relapsed/refractory B‐cell lymphomas. …”
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Biogeochemical evidence raises questions on the longevity of warming‐induced growth enhancements in wet boreal forests by Susan E. Ziegler, Sharon A. Billings, Frances A. Podrebarac, Kate A. Edwards, Andrea Skinner, Kate M. Buckeridge, Trevor C. VandenBoer

“…By assessing multiple soil N and P stocks, inputs, and stoichiometry, we observed three lines of evidence indicating that this greater P demand is met through a combination of plant tissue plasticity and adequate surface soil P supplies. …”
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Spindle-shaped efficient adsorbent NiCo2O4/MIL-53(Fe) for the removal of Congo red: Design, synthesis and performance studies by Bai Sun, Taoyou Zhou, Angang Hu, Yuxian Guo, Yun Wang, Lining Bao, Hao Huang, Mingjian Yi, Shuguang Zhu, Lingtao Kong

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Experimental study and model prediction of the influence of different factors on the mechanical properties of saline clay by Hui Cheng, Lingkai Zhang, Chong Shi, Pei Pei Fan

“…Canal water leakage exacerbates the salt expansion traits of such soil, damaging canal slope lining structures. To investigate the mechanical properties of saline clay, this study conducted indoor tests, including direct shear, compression, and permeation tests, and scanning electron microscopy (SEM) analysis of soil samples from typical sites. …”
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The Potential Proallergenic Activity of Tranzschelia pruni-spinosae and Phragmidium rubi-idaei in vitro Studies by Sztandera-Tymoczek M, Wdowiak-Wróbel S, Świderska U, Palusińska-Szysz M, Szuster-Ciesielska A

“…Immunofluorescence techniques were employed to assess cell integrity markers.Results: Extracts from T. pruni-spinosae and P. rubi-idaei significantly stimulated the production of proinflammatory cytokines IL-1β and GM-CSF in both cell lines, all of which are associated with the development of allergic responses. …”
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Dissection of the genetic basis and molecular mechanism of ovule number per ovary in oilseed rape (Brassica napus L.) by Muslim Qadir, Muslim Qadir, Muslim Qadir, Xinyi Lin, Farhan Nabi, Kishore Kumar Ashok, Xue-Rong Zhou, Qingbin Sun, Peiman Shi, Xinfa Wang, Jiaqin Shi, Hanzhong Wang

“…Phytohormone quantification of ovaries (at the ovule initiation stage) from two pools of high and low ONPO lines showed significant differences in the levels of nine sub-types of phytohormones, suggesting their important roles in regulating ovule number. …”
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A refined kidney tumor nephrometry system employed to screen pediatric patients who are eligible for nephron sparing surgery by Mingchuan Huang, Yingchun Fei, Zhihai Zhong, Hong Jiang, Longshan Liu, Juncheng Liu, Huanxi Zhang, Jun Li, Zhe Xu, Pengfei Gao, Pengfei Gao, Changxi Wang, Changxi Wang, Changxi Wang

“…According to the TUMORS nephrometry scoring system, there were 13, 34 and 23 kidney units classified as low, moderate and high complexity, respectively. Tumors that underwent RN or ex vivo removal exhibited higher complexity. …”
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Analysis of Polarized Dust Emission Using Data from the First Flight of SPIDER by P. A. R. Ade, M. Amiri, S. J. Benton, A. S. Bergman, R. Bihary, J. J. Bock, J. R. Bond, J. A. Bonetti, S. A. Bryan, H. C. Chiang, C. R. Contaldi, O. Doré, A. J. Duivenvoorden, H. K. Eriksen, J. P. Filippini, A. A. Fraisse, K. Freese, M. Galloway, A. E. Gambrel, N. N. Gandilo, K. Ganga, S. Gourapura, R. Gualtieri, J. E. Gudmundsson, M. Halpern, J. Hartley, M. Hasselfield, G. Hilton, W. Holmes, V. V. Hristov, Z. Huang, K. D. Irwin, W. C. Jones, A. Karakci, C. L. Kuo, Z. D. Kermish, J. S.-Y. Leung, S. Li, D. S. Y. Mak, P. V. Mason, K. Megerian, L. Moncelsi, T. A. Morford, J. M. Nagy, C. B. Netterfield, M. Nolta, R. O’Brient, B. Osherson, I. L. Padilla, B. Racine, A. S. Rahlin, C. Reintsema, J. E. Ruhl, M. C. Runyan, T. M. Ruud, J. A. Shariff, E. C. Shaw, C. Shiu, J. D. Soler, X. Song, A. Trangsrud, C. Tucker, R. S. Tucker, A. D. Turner, J. F. van der List, A. C. Weber, I. K. Wehus, D. V. Wiebe, E. Y. Young, Spider Collaboration

“…Using data from the first flight of Spider and from the Planck High Frequency Instrument, we probe the properties of polarized emission from interstellar dust in the Spider observing region. …”
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<i>In vitro</i> and <i>in vivo</i> tropism and biodistribution of recombinant simian adenovirus type 25 by Irina V. Vavilova, Tatiana A. Ozharovskaia, Olga V. Zubkova, Olga Popova, Daria V. Voronina, Polina P. Goldovskaya, Denis I. Zrelkin, Alina Sh. Dzharullaeva, Inna V. Dolzhikova, Dmitry V. Shcheblyakov, Denis Yu. Logunov, Alexander L. Gintsburg

“…The efficiency of in vitro transduction was evaluated on 15 different cell lines using recombinant adenovirus vectors expressing the enhanced green fluorescent protein (EGFP) reporter gene. …”
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Integration of single-cell transcriptomics and bulk transcriptomics to explore prognostic and immunotherapeutic characteristics of nucleotide metabolism in lung adenocarcinoma by Kai Zhang, Kai Zhang, Luyao Wang, Huili Chen, Lili Deng, Mengling Hu, Ziqiang Wang, Yiluo Xie, Chaoqun Lian, Xiaojing Wang, Xiaojing Wang, Jing Zhang

“…BackgroundLung adenocarcinoma (LUAD) is a highly aggressive tumor with one of the highest morbidity and mortality rates in the world. …”
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NALCN expression is down-regulated and associated with immune infiltration in gastric cancer by Xuewei Li, Xuewei Li, Na Wu, Chen Wang, Beibei Pei, Xiaoyan Ma, Jun Xie, Jun Xie, Wenhui Yang

“…Immunofluorescence staining confirmed that B cells and CD8 T cells were more abundant in GC tumor tissues with high NALCN expression, whereas Th17 and Th2 cells were less prevalent. …”
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Identification and validation of a prognostic signature of drug resistance and mitochondrial energy metabolism-related differentially expressed genes for breast cancer by Tiankai Xu, Chu Chu, Shuyu Xue, Tongchao Jiang, Ying Wang, Wen Xia, Huanxin Lin

“…Furthermore, we examined immune infiltration and tumor mutation burden of the genes within our model and scrutinized divergences in the immune microenvironment between high- and low-risk groups. Small hairpin RNA and lentiviral plasmids were designed for stable transfection of breast cancer cell lines MDA-MB-231 and HCC1806. …”
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Method for assessing the theoretical characteristics of small axial hydraulic turbines by D. V. Mylkin, A. V. Volkov, B. M. Orakhelashvili, A. A. Druzhinin, V. Yu. Lyapin

“…Construction of transmission lines to provide electricity to such areas is expensive and not always possible. …”
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Evaluation of in-vitro and in-silico antidiabetic potential, glucose metabolism, antioxidant, cytotoxicity and phytochemical content of Ipomoea bolusiana Schinz and Ipomoea crassip... by Garland Kgosi More, Nolitha Nkobole, Charmy Twala, Sechaba Machedi, Tebogo Amos Moswetsa, Ramakwala Christinah Chokwe

“…Background: Diabetes Mellitus is a chronic metabolic disorder caused by genetic disorders and other factors such as the use of certain medications, pancreatic injury, and autoimmune diseases such as rheumatoid arthritis and high blood pressure. However, several therapeutic agents are currently used to manage blood sugar levels, thus reducing the risk of complications. …”
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Targeting MYCN upregulates L1CAM tumor antigen in MYCN-dysregulated neuroblastoma to increase CAR T cell efficacy by Laura Grunewald, Lena Andersch, Konstantin Helmsauer, Silke Schwiebert, Anika Klaus, Anton G. Henssen, Teresa Straka, Marco Lodrini, Sebastian G. Wicha, Steffen Fuchs, Falk Hertwig, Frank Westermann, Alice Vitali, Carlotta Caramel, Gabriele Büchel, Martin Eilers, Kathy Astrahantseff, Angelika Eggert, Uta E. Höpken, Johannes H. Schulte, Thomas Blankenstein, Kathleen Anders, Annette Künkele

“…Primary neuroblastomas possessing high MYCN levels expressed lower levels of both the L1CAM transcript and L1CAM tumor antigen. …”
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Relationship of the gene pool of the Khants with the peoples of Western Siberia, Cis-Urals and the Altai-Sayan Region according to the data on the polymorphism of autosomic locus a... by V. N. Kharkov, N. A. Kolesnikov, L. V. Valikhova, A. A. Zarubin, M. G. Svarovskaya, A. V. Marusin, I. Yu. Khitrinskaya, V. A. Stepanov

“…Variants of different haplogroups of the Y-chromosome in the Khanty, Khakas and Tuvans go back to their common ancestral lines. The results of a comparative analysis of male samples indicate a close genetic relationship between the Khanty and Nenets, Komi, Udmurts and Kets. …”
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Outcomes of Idecabtagene Vicleucel Therapy in Patients with Relapsed/Refractory Multiple Myeloma: A Single-Institution Experience by Aaron Trando, Farid Ghamsari, Philip Yeung, Caitlin Costello, Ila Saunders, Ah-Reum Jeong

“…Six patients (24%) had high-risk cytogenetics while ten patients (40%) had extramedullary disease. …”
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