Bioactivity and metabolic profiling of crude extracts from endophytic bacteria linked to Solanum mauritianum scope: Discovery of antibacterial and anticancer properties by Abraham Goodness Ogofure, Ezekiel Green

“…The anticancer activity of the metabolites was evaluated against A549 Lung carcinoma cells and U87MG Glioblastoma cells (ATCC culture cell lines). The result revealed a diversity of bacterial endophytes, including Pantoea species, Luteibacter sp. …”
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Vertical Shear Instability in Thermally Stratified Protoplanetary Disks. II. Hydrodynamic Simulations and Observability by Han-Gyeol Yun, Woong-Tae Kim, Jaehan Bae, Cheongho Han

“…The magnitude of the observed velocity residual increases with the optical depth of the tracer used, as optically thick lines probe the regions near the disk surfaces.…”
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Geoelectric Field Estimations During Geomagnetic Storm in North China From SinoProbe Magnetotelluric Impedances by Qihe Shao, Ying Liu, Yinhe Luo, Graham Heinson, Yixian Xu, Jinsong Du, Chao Chen

“…However, in relation to locations of major power transmission lines, only the central part of North China experienced induced voltages exceeding 100 V.…”
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Inhibition of RAD51 by siRNA and Resveratrol Sensitizes Cancer Stem Cells Derived from HeLa Cell Cultures to Apoptosis by Graciela Ruíz, Heriberto A. Valencia-González, Ismael León-Galicia, Enrique García-Villa, Alejandro García-Carrancá, Patricio Gariglio

“…We found that CSC, derived from cervical cancer cell lines, overexpress RAD51 and are less sensitive to Etoposide (VP16). …”
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A Novel Bacteriophage with the Potential to Inhibit <i>Fusobacterium nucleatum</i>-Induced Proliferation of Colorectal Cancer Cells by Ho Yin Pekkle Lam, Meng-Jiun Lai, Pin-Chun Wang, Wen-Jui Wu, Li-Kuang Chen, Hsiang-Wei Fan, Chun-Chieh Tseng, Shih-Yi Peng, Kai-Chih Chang

“…Currently, bacteriophage therapy has gained interest because of its high selectivity to bacterial hosts and may become a realistic approach in treating bacteria-associated cancers. …”
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Enhancing glioblastoma therapy: unveiling synergistic anticancer effects of Onalespib - radiotherapy combination therapy by Julia Uffenorde, Mehran Hariri, Eleftherios Papalanis, Annika Staffas, Josefine Berg, Bo Stenerlöw, Hanna Berglund, Christer Malmberg, Diana Spiegelberg, Diana Spiegelberg

“…BackgroundGlioblastoma (GBM) is the deadliest form of brain cancer, impacting both adults and children, marked by exceptionally high morbidity and mortality rates, even with current standard treatments such as surgery, radiation therapy, and chemotherapy. …”
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TRIM8 inhibits porcine epidemic diarrhoea virus replication by targeting and ubiquitinately degrading the nucleocapsid protein by Zhenbin Bi, Wei Wang, Shanshen Gu, Yajing Zhou, Zhengchang Wu, Wenbin Bao, Haifei Wang

“…We created TRIM8 knockout and overexpression cell lines and discovered that TRIM8 can inhibit PEDV replication within host cells. …”
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Revolutionizing radiotherapy: gold nanoparticles with polyphenol coating as novel enhancers in breast cancer cells—an in vitro study by Simona Tarantino, Annalisa Bianco, Mariafrancesca Cascione, Alessandra Carlà, Lia Fiamà, Riccardo Di Corato, Livia Giotta, Paolo Pellegrino, Anna Paola Caricato, Rosaria Rinaldi, Valeria De Matteis

“…Gold nanoparticles (AuNPs) are particularly notable due to their high atomic number, which enhances radiation damage through the photoelectric effect. …”
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Fault current handling in large-scale MMC-HVDC systems: an improved approach with DC circuit breaker and fault current limiter by Rashid Hussain Chandio, Madad Ali Shah, Abdul Aziz Memon, Khawaja Haider Ali, Jahangeer Badar Soomro, Basem Alamri, Ahmed Althobaiti, Mohammed Alqarni

“…Given the increased vulnerability of high-voltage DC (HVDC) lines to the faults, there is a dire need for enhanced protection equipment capable of effectively handling fault currents. …”
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Application of selection Index for enhancing resistance to Cryptocarya irritans and Vibrio alginolyticus in large yellow croaker by Jiaying Wang, Jiaying Wang, Ji Zhao, Ji Zhao, Bo Liu, Hongshu Chi, Pengxing Jiang, Pengxing Jiang, Junzu Xiao, Junzu Xiao, Zhou Jiang, Zhou Jiang, Lingwei Miao, Lingwei Miao, Qian He, Qian He, Junjia Zeng, Junjia Zeng, Qiaozhen Ke, Qiaozhen Ke, Tao Zhou, Tao Zhou, Peng Xu, Peng Xu

“…Despite the high cost of genotyping and the limited economic return per individual that restricts the use of genome selection technology in aquatic species breeding, integrating multiple traits in a selection index can reduce costs and present a promising direction for fish breeding. …”
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Loss of p53 impairs death receptor expression and confers resistance to CD19 CAR T-cell therapy in BCP-ALL by Willem P. J. Cox, Noël M. M. Dautzenberg, Linde Dekker, Tesa Klenovsek, Annelisa M. Cornel, Marliek van Hoesel, Dorette S. van Ingen Schenau, Reno S. Bladergroen, Roland P. Kuiper, Laurens T. van der Meer, Friso G. Calkoen, Stefan Nierkens, Frank N. van Leeuwen

“…Furthermore, these data underscore the need for alternative curative therapies for this very high-risk patient group.…”
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Optimization of cultivation parameters for bovine respiratory syncytial virus strain Vologda/2019 by V. V. Kirpichenko, S. V. Kononova, I. N. Shumilova, A. A. Nesterov, M. V. Turkova, Ye. A. Bukhon, D. V. Romenskaya, A. V. Sprygin, B. L. Manin, O. P. Byadovskaya

“…It was established that the continuous cell lines of fetal bovine trachea (FBT) and calf kidney (RBT) are the most sensitive cell systems for the reproduction of the bovine respiratory syncytial virus strain Vologda/2019, the maximum accumulation of the virus was observed in these cell cultures. …”
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Prosaposin – A plausible biomarker in head and neck squamous cell carcinoma by Avradeep Datta, Rajandeep Kaur, Anshika Chauhan, Geeta Singh Boora, Himanshu Garg, Debajyoti Chatterjee, Jaimanti Bakshi, Sushmita Ghoshal, Arnab Pal

“…Objectives: Head and Neck Squamous Cell Carcinoma (HNSCC) is one of the leading cancers in developing countries with very high morbidity and mortality. One of the important reasons for the poor outcome is late diagnosis, which is majorly attributed to the non-availability of suitable diagnostic and prognostic biomarkers. …”
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The Transcription Factor SOX18 Inhibitor Small Molecule 4 Is a Potential Treatment of Cancer‐Induced Lymphatic Metastasis and Lymphangiosarcoma by Katja K. Koll, Martin M. Zimmermann, Patrick A. Will, Ulrich Kneser, Christoph Hirche

“…Methods and Results Human dermal lymphatic endothelial cells (HDLECs), lymphangiosarcoma cells (MO‐LAS), and other endothelial cell lines were cultured. We found that Sox18 exhibited high mRNA expression levels in both HDLEC and MO‐LAS. …”
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Improved ChIP Sequencing for H3K27ac Profiling and Super-Enhancer Analysis Assisted by Fluorescence-Activated Sorting of Formalin-Fixed Paraffin-Embedded Tissues by Nenggang Jiang, Zhihao Wen, Huan Tao, Hongyan Liao

“…In addition, we also evaluated the protocol using cultured pure cell lines, and the results indicated that the sequencing data obtained through this protocol had high fidelity and reproducibility. …”
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Regulation of S100A8/A9 (Calprotectin) Binding to Tumor Cells by Zinc Ion and Its Implication for Apoptosis-Inducing Activity by Yuichi Nakatani, Masatoshi Yamazaki, Walter J. Chazin, Satoru Yui

“…In contrast, when MM46 cells were incubated with S100A8/A9 in the presence of high levels of zinc, binding to cells was the same at 1 and 3 h. …”
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Validation of devices for characterization of hybrid 3D printed embroidery TENG for energy harvesting by HASAN TAHIR, Benny Malengier, Carla Hertleer, Lieva Van Langenhove

“…These features make the thread especially suitable for high production quality. It could be used as needle thread or bobbin thread. …”
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Barriers and facilitators to the conduct of critical care research in low and lower-middle income countries: A scoping review. by Bharath Kumar Tirupakuzhi Vijayaraghavan, Ena Gupta, Nagarajan Ramakrishnan, Abi Beane, Rashan Haniffa, Nazir Lone, Nicolette de Keizer, Neill K J Adhikari

“…Barriers and facilitators were classified along the lines of a previous review and based on additional themes that emerged. …”
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Molecular Detection and Isolation of Lumpy Skin Disease Virus during an Outbreak in West Hararghe Zone, Eastern Ethiopia by Umer Seid Geletu, Ahmedin Abdurehman Musa, Munera Ahmednur Usmael, Melaku Sombo Keno

“…Lumpy skin disease (LSD) is a highly contagious viral disease that causes significant economic losses in cattle populations globally. …”
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Synthesis of Silver and Zinc Oxide Nanoparticles Using Polystichum lentum Extract for the Potential Antibacterial, Antioxidant, and Anticancer Activities by Deepak Kumar Shrestha, Akash Budha Magar, Manisha Bhusal, Rabina Baraili, Ishwor Pathak, Pusp Raj Joshi, Niranjan Parajuli, Khaga Raj Sharma

“…In conclusion, the findings of the present study demonstrate the high antioxidant, antibacterial, and anticancer activities in Ag and ZnO nanoparticles synthesized using an aqueous extract of Polystichum lentum.…”
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