CD4 CAR-T cells targeting CD19 play a key role in exacerbating cytokine release syndrome, while maintaining long-term responses by Alice Bergamini, Barbara Camisa, Attilio Bondanza, Fabio Ciceri, Chiara Bonini, Monica Casucci, Beatrice Greco, Camilla Bove, Silvia Arcangeli, Laura Falcone, Rita El Khoury, Anna De Lucia

“…Therefore, the development of cell products with improved therapeutic indexes is highly demanded.Methods In this project, we investigated how CD4 and CD8 populations cooperate during CD19 CAR-T cell responses and what is their specific role in CRS development. …”
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Heterogeneity of motivations among crowdinvestors: Evidence from the football industry by Szczepan Kościółek

“…With the exception of the goal-oriented niche, crowdinvestors of football clubs are fans who are highly identified with the club and focused on supporting the cause of the campaign. …”
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Bioequivalence study of fluticasone propionate nebuliser suspensions in healthy Chinese subjects by Feng Cheng, Tao Shen, Fucheng Zhang, Chenghao Lei, Ye Zhu, GuoJun Luo, Dawei Xiao

“…BackgroundFluticasone propionate is a synthetic trifluoro-substituted glucocorticoid, a highly selective glucocorticoid receptor agonist. …”
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Correlation between Quantitative 13C-Urea Breath Test and Helicobacter pylori Treatment Success in a Population-Based Cohort by Doron Boltin, Zohar Levi, Tsachi Tsadok Perets, Hemda Schmilovitz-Weiss, Rachel Gingold-Belfer, Ram Dickman, Iris Dotan

“…There are continual efforts to identify factors which influence the success of first-line therapy for Helicobacter pylori (H. pylori) infection. …”
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Macro- and microscopic anatomy of the digestive tract in the red-eared slider (Emydidae: Trachemys scripta elegans). by Nonoha Miyai, Takuma Kozono, Tatsu Kuriki, Mai Todoroki, Tomoaki Murakami, Kyosuke Shinohara, Toshinori Yoshida, Tetsuhito Kigata

“…The red-eared sliders (Emydidae: Trachemys scripta) is characterised by a high adaptability to a variety of environment and threatens the habitat of Japanese native species. …”
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Determination of Internal Erosion and Permittivity of Biopolymer-Added Geosynthetic Clay Liners by Hakkı Oral Özhan

“…Geosynthetic clay liner (GCL) can be used as a lining material in freshwater reservoirs due to its very low hydraulic conductivity. …”
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A pan-cancer analysis: predictive role of ZNF32 in cancer prognosis and immunotherapy response by Minghan Li, Chang Su, Qianru Wang, Yuetong Chen, Di Jiang, Weijia Wang, Shunjin Chen, Xiangping Li, Ming Fu, Juan Lu

“…Abstract The zinc finger protein 32 (ZNF32) has been associated with high expression in various cancers, underscoring its significant function in both cancer biology and immune response. …”
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Analysis of Landslides Susceptibility of the Erzincan-Sivas Road and Its Surrounding Region by the AHP Method based on Geographic Information Systems (GIS) by Betül Güneş, Ali Ümran Kömüşcü

“…The findings of the analysis indicate that a nearly 6,39 ha area along the Erzincan-Sivas highway has an extremely high susceptibility to landslides while 120 ha has a high susceptibility to landslides. …”
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Evaluating the level of digitalization of the innovation process with artificial intelligence approach in the digital transformation of knowledge-based companies by ali Bagheri, reza radfar, sepehr ghazinoory

“…In this method, the number of membership functions is 5 functions representing very low, low, medium, high and very high. Research findings A number of 290 articles were selected among the whole, which had the citation higher than 1. …”
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Prevalence and determinants of nasal carriage of penicillin non-susceptible Streptococcus pneumoniae: a cross-sectional household survey in northern VietnamResearch in context by Costanza Tacoli, Hien Anh Thi Nguyen, Tu Cam Thi Nguyen, Bich Ngoc Thi Vu, Max van Wijk, Quynh Dieu Pham, Huong Kieu Thi Tran, Thuong Hong Thi Nguyen, Trang Thu Nguyen, Tung Son Trinh, Dung Tien Viet Vu, Hoang Huy Tran, Thai Duy Pham, Duc Anh Dang, Tien Dac Tran, Duong Thanh Nguyen, H. Rogier van Doorn, Thomas Kesteman, Sonia Lewycka

“…Summary: Background: Beta-lactams remain the first-line treatment of Streptococcus pneumoniae infections despite the increasing global prevalence of penicillin-resistant/non-susceptible strains. …”
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Assessing and predicting the value of ecosystem services in Sanya City, Hainan Island, China by Peihong Song, Qiu Yang, Wenyin Wu, Tianyan Su, Yamin Jiang, Jingli Lu, Zhongyi Sun, Jie Zhang, Rui Yu, Peng Wang, Lan Wu, Huai Yang, Wenjie Liu

“…Considering the LUCC characteristics and land-use strategies in Sanya, the Synthetical Protection Scenario was identified as the optimal choice to balance the red line between farmland and the ecological development of civilization. …”
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Nitrogen uptake and remobilization from pre- and post-anthesis stages contribute towards grain yield and grain protein concentration in wheat grown in limited nitrogen conditions by Sandeep Sharma, Tarun Kumar, M. John Foulkes, Simon Orford, Anju Mahendru Singh, Luzie U. Wingen, Venkatesh Karnam, Lekshmy S. Nair, Pranab Kumar Mandal, Simon Griffiths, Malcolm J. Hawkesford, Peter R. Shewry, Alison R. Bentley, Renu Pandey

“…Several N-efficient lines also exhibited positive grain protein deviation (GPD), combining high grain yield and GPC. …”
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Knowledge, attitudes and practices of oral HIV pre-exposure prophylaxis (PrEP) among healthcare workers in the Ekurhuleni District, South Africa by E Mahlare, E Ramutshila, A Musekiwa, L Kuonza, T Mabuto

“…Despite HIV pre-exposure prophylaxis (PrEP) being one of the highly effective approaches to preventing HIV, and being freely available through primary healthcare clinics (PHCs), the uptake of HIV PrEP in South Africa (SA) is low. …”
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A New Unsaturated Aliphatic Anhydride from Aspergillus candidus T1219W1, an Endophytic Fungus, from Pittosporum mannii Hook f. by Gaëlle Talle Juidzou, Elodie Gisèle Mouafo Anoumedem, Denis Kehdinga Sema, Virginie Flaure Tsague Tankeu, Peron Bosco Leutcha, Larissa Yetendje Chimi, Jean Paul Dzoyem, Simeon Kouam Fogue, Norbert Sewald, M. Iqbal Choudhary, Alain Meli Lannang

“…However, no cytotoxic activity was observed against 3T3 cell lines.…”
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Three-Dimensional Point Cloud Displacement Analysis for Tunnel Deformation Detection Using Mobile Laser Scanning by Mahamadou Camara, Liying Wang, Ze You

“…Shield tunnels are increasingly monitored using 3D laser scanning technology to generate high-resolution point cloud data, which serve as a critical foundation for precise deformation analysis. …”
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Design of a Compact UWB MIMO Antenna without Decoupling Structure by Yanjie Wu, Kang Ding, Bing Zhang, Jianfeng Li, Duolong Wu, Kun Wang

“…A compact high isolation ultrawideband (UWB) multiple-input-multiple-output (MIMO) antenna is designed. …”
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Impact of the crosstalk between the PTEN and PAFR as well as PAFR and EGFR pathways in cancer by Anita Thyagarajan, Zaid Sirhan, Ravi P. Sahu

“…Thus, an impaired, mutated, or loss of PTEN is associated with low survival or high tumor recurrence rates in cancer patients. Importantly, high tumor expression of a G-protein coupled platelet-activating factor-receptor (PAFR) is associated with increased tumor progression as well as decreased overall survival and poor prognosis in malignancies such as non-small cell lung cancer (NSCLC). …”
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Characterising the change rule of freshness and inorganic anions in reconstituted tobacco pulp with oscillation time by Huayu Li, Shaohui Yan, Hongtao Xu, Xiaoyu Li, Runan Wang, Ying Yan, Pengyu Li, Litao Zhang, Yanqing Wang, Mengmeng Zu, Yibo Wang

“…Abstract In order to study the change rule of freshness and acid ions in reconstituted tobacco slurry, the content changes of 17 organic acids and 5 inorganic anions in reconstituted tobacco slurry with different residence times under confined condition were determined by on-line solid-phase extraction ion chromatography in this study. …”
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Candida Albicans Candidalysin ECE1 Gene − A Potent Virulence Factor for Oral Squamous Cell Carcinoma and Oral Potentially Malignant Disorders by Mani B. Subramani, Krishnan Mahalakshmi, Bharathy Jaya, Sankar Leena Sankari, Venkatesan N. Kumar

“…Future studies in characterizing their virulence on normal cell lines would clarify the importance of candidalysin in promoting oncogenesis.…”
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Ly6E on tumor cells impairs anti-tumor T-cell responses: a novel mechanism of tumor-induced immune exclusion by Lan Hailin, Chen Yiting, Wu Yue, Li Lijun, Zhang Renlu, Chen Yunhan, Zhu Yanyang, Zhang Qiuyu

“…After analyzing Ly6E expression levels in human breast cancer tissues and tumor cell lines, we generated Ly6E knockout (KO) and overexpression (OE) mouse cell lines. …”
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