CircTTC13 promotes sorafenib resistance in hepatocellular carcinoma through the inhibition of ferroptosis by targeting the miR-513a-5p/SLC7A11 axis by Ying Zhang, Ruiwei Yao, Mingyi Li, Chongkai Fang, Kunliang Feng, Xiuru Chen, Jinan Wang, Rui Luo, Hanqian Shi, Xinqiu Chen, Xilin Zhao, Hanlin Huang, Shuwei Liu, Bing Yin, Chong Zhong

“…Abstract The high mortality rate from hepatocellular carcinoma (HCC) is due primarily to challenges in early diagnosis and the development of drug resistance in advanced stages. …”
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Machine learning analysis of pathological images to predict 1-year progression-free survival of immunotherapy in patients with small-cell lung cancer by Hirotaka Matsumoto, Hiroaki Akamatsu, Nobuyuki Yamamoto, Yuki Sato, Daichi Fujimoto, Yoshihiko Taniguchi, Motohiro Tamiya, Yasuhiro Koh, Junya Fukuoka, Hisashi Tanaka, Naoki Furuya, Ryota Shibaki, Tsukasa Nozawa, Akira Sano, Yuka Kitamura, Takashi Kijima, Toshihide Yokoyama, Satoru Miura, Akito Hata, Jun Sugisaka

“…The PFS was longer in the high efficacy group than in the low efficacy group in all three models (patient information model, HR 0.468, 95% CI 0.287 to 0.762; pathological image model, HR 0.334, 95% CI 0.117 to 0.628; combined model, HR 0.353, 95% CI 0.195 to 0.637). …”
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A Single-Mode 852-nm Faraday Laser by Zhiyang Wang, Zijie Liu, Jianxiang Miao, Hangbo Shi, Xiaomin Qin, Xiaolei Guan, Jia Zhang, Pengyuan Chang, Tiantian Shi, Jingbiao Chen

“…Realizing always atomic translation frequency output, single-mode, high frequency stability, narrow linewidth semiconductor lasers, is one of the ultimate visions of areas related to quantums, such as quantum precision measurement and atomic physics. …”
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Differences in Optical Two-dimensional Morphological Characteristics of Downward Lightning Channels with Different Polarities by Mei Ji, Lü Weitao, Qi Qi, Xu Weiqun, Wu Bin, Ma Ying, Liu Hengyi, Chen Lüwen, Zhang Yang

“…Although the frequency of positive CG lightning is relatively low, these events are more likely to produce high current peaks compared to negative CG lightning. …”
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The chromosome-level genome provides insights into the adaptive evolution of the visual system in Oratosquilla oratoria by Daizhen Zhang, Xiaoli Sun, Lianfu Chen, Lianyu Lin, Chijie Yin, Wenqi Yang, Jun Liu, Qiuning Liu, Huabin Zhang, Senhao Jiang, Yongxin Li, Boping Tang, Gang Wang

“…Abstract Background The marine crustacean Oratosquilla oratoria is economically significant in seafood and aquaculture industries. However, the lack of high-quality genome assembly has hindered our understanding of O. oratoria, particularly the mechanisms underlying its developed visual system. …”
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Identification and expression analysis of c-type and g-type lysozymes genes after Aeromonas hydrophila infection in African catfish by Hasan Nasrullah, Yanti Inneke Nababan, Dwi Hany Yanti, Dian Hardiantho, Sri Nuryati, Muhammad Zairin Junior, Julie Ekasari, Alimuddin Alimuddin

“…ABSTRACT Lysozymes play an important role in the first line of defense in fish and potentially used as an immunity status biomarker and immune responses evaluation in fish, which often found in two types, i.e. chicken-type and goose-type (c- and g-type, respectively). …”
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Genome-wide CRISPR-based screen identifies E2F transcription factor 1 as a regulator and therapeutic target of aristolochic acid-induced nephrotoxicity by Ziqi Liu, Huan Gao, Guoliang Li, Yongjiang Yu, Mengxing Cui, Honghao Peng, Xinchao Guan, Xue Zhang, Zhihan Zhang, Xiaoyu Shen, Shen Chen, Daochuan Li, Liping Chen, Yongmei Xiao, Wen Chen, Lili Liu, Qing Wang

“…Additionally, using the high-throughput experiment- and reference-guided database of traditional Chinese medicine (HERB), cannabidiol (CBD) was identified as an inhibitor of E2F1 by suppressing the activity of NF-κB pathway. …”
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Early initiation of intravenous cyclophosphamide and one‐year outcome in super‐refractory cryptogenic‐new onset refractory status epilepticus by Yasufumi Yorichika, Shuichiro Neshige, Hideaki Sakahara, Narumi Ono, Megumi Nonaka, Yuichiro Tagane, Tomoaki Watanabe, Keisuke Tachiyama, Haruka Ishibashi, Masahiro Nakamori, Takeo Shishido, Shiro Aoki, Hiroki Ueno, Yu Yamazaki, Takahiro Iizuka, Hirofumi Maruyama

“…Despite initiating antiseizure medications (ASMs) and first‐line immunotherapy (intravenous‐methylprednisolone and immunoglobulins) within a median of 3 days from onset, SE persisted >5 days. …”
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Collagen prolyl 4-hydroxylase subunit α member-induced head and neck squamous cell carcinoma aggressiveness is antagonized by LLGL2 via redu... by Xu Miao, Shi Run, Yang Jie, Chen Heng, Liu Shihua, Yu Shupei, Li Sasa, He Wenqiang, Sy Man-Sun, Lu Mingjian, Zhang Huixia, Li Chaoyang

“…Silencing of LLGL2 in the human oral squamous cell line Cal-27 upregulates the expression of occludin and increases cancer cell invasion and migration. …”
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PREFERENSI PEMANFAATAN RUANG PUBLIK DI RUMAH SUSUN SEWA MARISO DI MAKASSAR by Ratriana Said Bunawardi, Burhanuddin Amin

“…Corridors that are designed as a connecting line between residential units are overloaded due to personal activity interventions. …”
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L’ensemble monumental du Pâtis à Vieillevigne (Loire-Atlantique) : un nouvel exemple de complexe sur cour laténien en Gaule by Yann Dufay-Garel, Marie Grall, Sandrine Paradis-Grenouillet, Rémy Wassong

“…The construction of the building’s load-bearing structure is homogeneous, with no signs of repair. It consists of three lines of posts along each wing, forming two naves, divided into nine bays by ten rows of three posts. …”
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Warm and humid environment induces gut microbiota dysbiosis and bacterial translocation leading to inflammatory state and promotes proliferation and biofilm formation of certain ba... by Yinrui Guo, Jianlang He, Shaojie Li, Shiqi Zou, Haiting Zhang, Xin Yang, Jian Wang

“…In the Lingnan region of China, high summer temperatures and humidity often cause symptoms like diminished appetite, sticky tongue coating, sticky stool, unsatisfactory defecation, lethargy, and joint heaviness. …”
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Vertical gradients of neutral winds observed by ICON and estimated by the Horizontal Wind Model during the geomagnetic storm on August 26−28, 2021 by JiaWei Wu, Chao Xiong, YuYang Huang, YunLiang Zhou

“…In this study, we used the red-line measurements of MIGHTI to compare with the results estimated by Horizontal Wind Model 14 (HWM14). …”
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Laser powder bed fusion processed LaCe(Fe, Mn, Si)₁₃ lattices for magnetic refrigeration: Process optimization, microstructure, and magnetocaloric performance by Kun Sun, Yuting Zhang, Sheng Li, Zhaohe Gao, Xue Cao, Ziling Peng, Pengyan Huang, Abd El-Moez A. Mohamed, Zhigang Zheng, Minki Jeong, Yu-Lung Chiu, Yang Lu, Moataz M. Attallah

“…The relationship between the defect fraction of the fabricated thin wall and the line energy density (EL) and hatch (h) is established. …”
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Resistome phylodynamics of multidrug-resistant Shigella isolated from diarrheal patients by Asaduzzaman Asad, Md. Abu Jaher Nayeem, Md. Golam Mostafa, Ruma Begum, Shah Nayeem Faruque, Suraia Nusrin, Israt Jahan, Shoma Hayat, Zhahirul Islam

“…Notably, two conjugative MDR plasmids included nearly all potential ARGs, conferring resistance to first-line drugs for shigellosis. Two third-generation cephalosporin-resistant [wubC-blaCTX-M-15-ISEcp1 and blaTEM-1] and two macrolide-resistant mobile genomic islands (GIs) [mphA-mrx-mph(R)A-IS6100 and mphE-msrE-IS482-IS6] had emerged in Shigella in Bangladesh. …”
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Co-isolation of human donor eye cells and development of oncogene-mutated melanocytes to study uveal melanoma by Yunxi Chen, Eva Jin, Mohamed Abdouh, Éric Bonneil, Daniel Alexander Jimenez Cruz, Thupten Tsering, Qianqian Zhou, Aurélie Fuentes-Rodriguez, Alexandra Bartolomucci, Alicia Goyeneche, Solange Landreville, Miguel N. Burnier, Julia V. Burnier

“…However, there are no commercially available NCM cell lines, nor is there a detailed protocol for developing an oncogene-mutated CM line (MutCM) to study UM development. …”
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Prognostic Value of TRPM7 Expression and Factor XIIIa-Expressing Tumor-Associated Macrophages in Gastric Cancer by Muhammet Calik, Ilknur Calik, Gokhan Artas, Ibrahim Hanifi Ozercan

“…TRPM7 overexpression was closely related to high depth of tumor invasion (p<0.001, ANOVA), increased lymph node metastasis (p<0.001, ANOVA), and high distant metastasis rate (p<0.001, Mann-Whitney U). …”
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The Heisenberg-RIXS instrument at the European XFEL by Justine Schlappa, Giacomo Ghiringhelli, Benjamin E. Van Kuiken, Martin Teichmann, Piter S. Miedema, Jan Torben Delitz, Natalia Gerasimova, Serguei Molodtsov, Luigi Adriano, Bernard Baranasic, Carsten Broers, Robert Carley, Patrick Gessler, Nahid Ghodrati, David Hickin, Le Phuong Hoang, Manuel Izquierdo, Laurent Mercadier, Giuseppe Mercurio, Sergii Parchenko, Marijan Stupar, Zhong Yin, Leonardo Martinelli, Giacomo Merzoni, Ying Ying Peng, Torben Reuss, Sreeju Sreekantan Nair Lalithambika, Simone Techert, Tim Laarmann, Simo Huotari, Christian Schroeter, Burkhard Langer, Tatjana Giessel, Jana Buchheim, Grzegorz Gwalt, Andrey Sokolov, Frank Siewert, Robby Buechner, Vinicius Vaz da Cruz, Sebastian Eckert, Chun-Yu Liu, Christian Sohrt, Christian Weniger, Annette Pietzsch, Stefan Neppl, Friedmar Senf, Andreas Scherz, Alexander Föhlisch

“…It is based on a spherical grating with variable line spacing and a position-sensitive 2D detector. …”
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Pageblug Jawa Kuna: Menggagas Folklor di Jawa Tengah sebagai Upaya Mitigasi Bencana Wabah Melalui Kartun Bergambar by Fitri Nur Lita Indriana, Yogi Aji Pangestu, Bintang Amanda, Anita Damar Ranti, Rabith Jihan Amaruli

“…Incorporating cultural values rooted in local wisdom can be a highly effective approach to disaster mitigation, particularly among the younger generation. …”
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A Rapid Biochemical and Radiological Response to the Concomitant Therapy with Temozolomide and Radiotherapy in an Aggressive ACTH Pituitary Adenoma by Ana Misir Krpan, Tina Dusek, Zoran Rakusic, Mirsala Solak, Ivana Kraljevic, Vesna Bisof, David Ozretic, Darko Kastelan

“…In the last eight years temozolomide (TMZ) has been used as the last-line treatment modality for aggressive pituitary tumors to be applied after the failure of surgery, medical therapy, and radiotherapy. …”
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