Self-reports map the landscape of task states derived from brain imaging by Brontë Mckeown, Ian Goodall-Halliwell, Raven Wallace, Louis Chitiz, Bridget Mulholland, Theodoros Karapanagiotidis, Samyogita Hardikar, Will Strawson, Adam Turnbull, Tamara Vanderwal, Nerissa Ho, Hao-Ting Wang, Ting Xu, Michael Milham, Xiuyi Wang, Meichao Zhang, Tirso RJ Gonzalez Alam, Reinder Vos de Wael, Boris Bernhardt, Daniel Margulies, Jeffrey Wammes, Elizabeth Jefferies, Robert Leech, Jonathan Smallwood

“…., those inferred from measures of brain activity). Here, we used machine learning to show that self-reported descriptions of experiences across tasks can reliably map the objective landscape of task states derived from brain activity. …”
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Early Pathologic Findings of Bronchiolitis Obliterans after Allogeneic Hematopoietic Stem Cell Transplantation: A Proposal from a Case by Rie Nakamoto-Matsubara, Hidekazu Nishikii, Kenji Yamada, Masafumi Ito, Yuichi Hasegawa, Naoki Kurita, Naoshi Obara, Yasushi Okoshi, Kazumi Suzukawa, Yasuhisa Yokoyama, Mamiko Sakata-Yanagimoto, Masayuki Noguchi, Shigeru Chiba

“…Therefore, the diagnosis of the disease is based on the pulmonary function test using the National Institute of Health consensus criteria. Here, we report a case of slowly progressive BO. …”
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Enhanced phosphorus weathering contributed to Late Miocene cooling by Yi Zhong, Zhiguo Li, Xuefa Shi, Terry Isson, Jimin Yu, Sev Kender, Zhou Liang, George E. A. Swann, Alex Pullen, Michael E. Weber, Jinlong Du, Juan C. Larrasoaña, Jingyu Zhang, Yafang Song, F. J. González, Stefanie Kaboth-Bahr, Hai Li, Qi Zhang, Debo Zhao, Wei Cao, Mingyu Zhao, Qingsong Liu

“…Despite its relevance for understanding the climate system, the driving mechanisms underlying profound climate and carbon cycle changes – including the enigmatic Late Miocene cooling from 7 to 5.4 million years ago – remain unclear. Here, we present magnetic and geochemical paleoceanographic proxies from a hydrogenetic ferromanganese crust retrieved in the northwestern Pacific Ocean. …”
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Structural insights into the activation mechanism of the human zinc-activated channel by Xuhang Lu, Dongmei Li, Yaojie Wang, Gaohua Zhang, Tianlei Wen, Yue Lu, Nan Jia, Xuedi Wang, Shenghai Chang, Xing Zhang, Jianping Lin, Yu-hang Chen, Xue Yang, Yuequan Shen

“…The molecular mechanism that ligands use to activate ZAC remains elusive. Here, we present three cryo-electron microscopy reconstructions of human ZAC (hZAC) under different conditions. …”
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Late Miocene Tapiridae from Vallès-Penedès Basin (NE Iberian Peninsula): taxonomic and paleoenvironmental implications by Luca Pandolfi, Sara G. Arranz, Sergio Almécija, Jordi Galindo, Àngel H. Luján, Marta Pina, Alessandro Urciuoli, Isaac Casanovas-Vilar, David M. Alba

“…Abstract European Miocene tapirs (Perissodactyla, Tapiridae) are mainly documented by isolated and fragmentary remains, and little is known about the morphological variability of the various recognized species, in particular concerning the deciduous dentition. Here, we describe new material from three Vallesian (Late Miocene) sites of the Vallès-Penedès Basin (NE Iberian Peninsula): Creu de Conill 20 (CCN20; earliest MN9, 11.2 Ma), Can Llobateres 1 (CLL1; earliest MN10, 9.8 Ma), and Can Gambús-Illeta 5 (CGS-I5; MN10, 9.7–9.1 Ma). …”
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Increases in the susceptibility of human endometrial CD4+ T cells to HIV-1 infection post-menopause are not dependent on greater viral receptor expression frequency by Landon G. vom Steeg, Zheng Shen, Jane Collins, Mickey V. Patel, Fiona D. Barr, Daniel C. Hopkins, Christina Ochsenbauer, Charles R. Wira

“…Epidemiological evidence suggests that post-menopausal women are more susceptible to HIV infection following sexual intercourse than are younger cohorts for reasons that remain unclear. Here, we evaluated how menopause-associated changes in CD4+ T cell numbers and subsets as well as HIV coreceptor expression, particularly CCR5, in the endometrium (EM), endocervix (CX), and ectocervix (ECX) may alter HIV infection susceptibility. …”
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Migrasomes derived from human umbilical cord mesenchymal stem cells: a new therapeutic agent for ovalbumin-induced asthma in mice by Weifeng Gu, Tingting Zheng, Wen Li, Xinkai Luo, Xiaowei Xu, Ying Wang, Chaoming Mao, Yongbin Ma, Liyang Dong

“…The therapeutic effects of migrasomes on airway inflammation in ovalbumin (OVA)-induced asthmatic mice were evaluated by hematoxylin-eosin (HE) and periodic-acid schiff (PAS) staining, and their mechanism were further testified by immunofluorescent staining, real-time PCR and flow cytometry. Results Here, we showed that inhibition of migrasomes’ production dramatically impaired the anti-inflammatory effects of hUCMSCs in OVA animals, as evidenced by a notable increase in both the infiltration of inflammatory cells and the number of epithelial goblet cells. …”
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Virtual Integration of Satellite and In-situ Observation Networks (VISION) v1.0: In-Situ Observations Simulator (ISO_simulator) by M. R. Russo, M. R. Russo, S. L. Bartholomew, S. L. Bartholomew, D. Hassell, D. Hassell, A. M. Mason, E. Neininger, A. J. Perman, D. A. J. Sproson, D. Watson-Parris, D. Watson-Parris, N. L. Abraham, N. L. Abraham

“…A standalone code, In-Situ Observations Simulator, or ISO_simulator for short, is described here: this software reads modelled variables and observational data files and outputs model data interpolated in space and time to match observations. …”
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PTOV1 exerts pro-oncogenic role in colorectal cancer by modulating SQSTM1-mediated autophagic degradation of p53 by Yongli Fan, Yuqin Li, Xia Luo, Shiqi Xiang, Jia Hu, Jingchun Zhan, Weilong Chang, Rui Deng, Xianwen Ran, Yize Zhang, Yudie Cai, Weiwei Zhu, Huifen Wang, Zhibo Liu, Di Wang

“…Immunofluorescence assay, western blot and transmission electron microscopy (TEM) analysis were used to evaluated the effects of PTOV1 on autophagy. Results Here, we revealed that PTOV1 was highly expressed in human CRC tissues, especially at advanced stages, and associated with reduced survival time among CRC patients. …”
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Exploring how graft length shapes root system architecture and morphology in grapevine rootstocks by Mathieu Larrey, Jean-Pascal Tandonnet, Clément Saint Cast, Sarah Jane Cookson, Philippe Vivin

“…The insights gathered here contribute to a deeper understanding of the mechanisms governing root development in grafted grapevines, thereby informing strategies to enhance grafting techniques and optimize grapevine cultivation. …”
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Intra-articular Glenoid Fracture Managed by Arthroscopic Fixation and Open Reduction and Internal Fixation Techniques: An Analytical Study by Prahalad K Singhi, Sivakumar Raju, Chidambaram Muthu, Gopi Kumarasamy, Vinoth Thangamani, Muthukishore Marichamy

“…Operative treatment has evolved from extensive open reduction to arthroscopic surgery. Here, we analyzed the intra-articular glenoid fractures, which were managed by conservative, open, or arthroscopic fixation (ARIF) to derive a treatment algorithm. …”
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A gut-derived Streptococcus salivarius produces the novel nisin variant designated nisin G and inhibits Fusobacterium nucleatum in a model of the human distal colon microbiome by Garreth W. Lawrence, Enriqueta Garcia-Gutierrez, A. Kate O’Mahony, Calum J. Walsh, Paula M. O'Connor, Máire Begley, Caitriona M. Guinane, Paul D. Cotter

“…Nisin G-producing S. salivarius DPC6487 demonstrated the ability to control an infection of F. nucleatum in a simulated model of the human distal colon while exerting minimal impact on the surrounding microbiota. Here, we describe this nisin variant produced by S. salivarius, a species that is frequently a focus for probiotic development. …”
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Odpowiedź na pracę dr. Pawła E. Tomaszewskiego pt. „Komentarz do artykułu Mariusza W. Majewskiego opublikowanego w Studia Historiae Scientiarum 17 (2018), ss. 89–117” by Mariusz W. Majewski

“…However, the problem arises when an author of a future publication has only few sources at his disposal, or even only one, which was the case here. The article answers the doubts bothering Paweł E. …”
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Gaps in our understanding of ice-nucleating particle sources exposed by global simulation of the UK Earth System Model by R. J. Herbert, A. Sanchez-Marroquin, A. Sanchez-Marroquin, D. P. Grosvenor, D. P. Grosvenor, K. J. Pringle, S. R. Arnold, B. J. Murray, K. S. Carslaw

“…Despite very large spatial and temporal variability in INP properties, many climate models do not currently represent the link between (i) the global distribution of aerosols and INPs and (ii) primary ice production in clouds. Here we use the UK Earth System Model to simulate the global distribution of dust, marine-sourced, and black carbon INPs suitable for immersion-mode freezing of liquid cloud droplets over an annual cycle. …”
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Dimorphos’s Material Properties and Estimates of Crater Size from the DART Impact by Angela M. Stickle, Kathryn M. Kumamoto, Dawn M. Graninger, Mallory E. DeCoster, Wendy K. Caldwell, Jason M. Pearl, J. Michael Owen, Olivier Barnouin, Gareth S. Collins, R. Terik Daly, Isabel Herreros, Jens Ormö, Jessica Sunshine, Carolyn M. Ernst, Toshi Hirabayashi, Simone Marchi, Laura Parro, Harrison Agrusa, Megan Bruck Syal, Nancy L. Chabot, Andy F. Cheng, Thomas M. Davison, Elisabetta Dotto, Eugene G. Fahenstock, Fabio Ferrari, Martin Jutzi, Alice Lucchetti, Robert Luther, Nilanjan Mitra, Maurizio Pajola, Sabina Raducan, KT Ramesh, Andrew S. Rivkin, Alessandro Rossi, Paul Sánchez, Stephen R. Schwartz, Stefania Soldini, Jordan K. Steckloff, Filippo Tusberti, Kai Wünnemann, Yun Zhang

“…Approach observations and those following the DART impact have provided crucial knowledge that narrows the parameter space relevant to modeling the impact into Dimorphos. Here we present the results of a suite of hydrocode simulations of the DART impact on Dimorphos. …”
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Dépôts et pratiques symboliques dans l’établissement aristocratique gaulois de Varennes-sur-Seine, la Justice (Seine-et-Marne) by Jean-Marc Séguier, Ginette Auxiette, Fabien Pilon

“…Their orientation favors an eastern axis for the upper portion of the body (cranial fragments, scapula, humeral diaphysis) and the opposite, western side for the lower limbs (femoral diaphyses). Here, as elsewhere, the handling and exhibition of skeletal human remains, extracted from burials or collected from excarnation platforms, are part of rituals that sit at the crossroads between beliefs and systems of social representation. …”
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Vibration Energy Color Doppler Imaging (VECDI) in Evaluating the Effect of Screw Fixation on Sacroiliac Joint Stiffness: A Prospective Pilot Study by Caleb Gottlich, Thomas Githens, Alex Drusch, Neil Jain, Cyrus Caroom, Phillip S. Sizer

“…Prior to this study, the mainstay of evaluation was subjective indexes, such as the ODI. Here we propose VECDI as a potentially objective tool in SIJ assessment. …”
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Exploring perinatal mesenchymal stromal cells as a potential therapeutic strategy for rheumatoid arthritis by Stefano Alivernini, Alice Masserdotti, Marta Magatti, Anna Cargnoni, Andrea Papait, Antonietta R. Silini, Jacopo Romoli, Sara Ficai, Clara Di Mario, Elisa Gremese, Barbara Tolusso, Ornella Parolini

“…Specifically, in experimental models of RA, treatment with perinatal MSC resulted in a strong reduction of articular damage, which was associated with the modulation of both inflammation and activation of stromal resident cells in the synovial tissue. Here, we present in vitro and in vivo evidence supporting the use of perinatal MSC in RA. …”
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