Dynamically Cyclic Fe2+/Fe3+ Active Sites as Electron and Proton-Feeding Centers Boosting CO2 Photoreduction Powered by Benzyl Alcohol Oxidation by Ben Lei, Gaofeng Zhou, Zhongyou Gong, Chao Liu, Ying Zhou, Vitaliy P. Guro, Yanjuan Sun, Jianping Sheng, Fan Dong

“…Solar-driven CO2 photoreduction holds promise for sustainable fuel and chemical productions, but the complex proton-coupled multi-electron transfer processes and sluggish oxidation half-reaction kinetics substantially hinder its efficiency. Here, we devised a rational catalyst design to address these challenges by fabricating ferrocene carboxylic acid-functionalized Cs3Sb2Br9 nanocrystals (CSB-Fc NCs), which facilitate simultaneous benzyl alcohol oxidation and CO2 reduction reactions under visible-light irradiation. …”
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Climate change and the sustainable use of medicinal plants: a call for “new” research strategies by Olha Mykhailenko, Olha Mykhailenko, Banaz Jalil, Lyndy J. McGaw, Javier Echeverría, Marce Takubessi, Marce Takubessi, Michael Heinrich, Michael Heinrich

“…Their economic importance, combined with rising demands and specific risks of overexploitation, are also key factors considered here. The suggested framework for the sustainability of medicinal and other high-value plant-based products in the phytopharmaceutical industry emphasises strategies that promote conservation and sustainable resource use. …”
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Six Sigma Approach to Developing a Microgrid Station for Research and Teaching by Gabriel Nasser Doyle de Doile, Miguel Castilla, Pedro Paulo Balestrassi, Antonio Carlos Zambroni de Souza, Jaume Miret

“…As electrical grids are dynamic systems in constant evolution, a new IDDOV roadmap should be carried out in future studies, to enhance the test bed recommended here.…”
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Optimal Inflow Performance Relationship Equation for Horizontal and Deviated Wells in Low-Permeability Reservoirs by Liqiang Wang, Zhengke Li, Mingji Shao, Yinghuai Cui, Wenbo Jing, Wei Zhang, Maoxian Wang

“…The other types of IPR equations are the Wiggins-Russell-Jennings, Klins-Majcher, Vogel, Fetkovich, Bendakhlia-Aziz, and Harrison equations, listed here in order from good to poor in accuracy.…”
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On the measurement of microclimate by Ilya M. D. Maclean, James P. Duffy, Stef Haesen, Sanne Govaert, Pieter De Frenne, Thomas Vanneste, Jonathan Lenoir, Jonas J. Lembrechts, Marcus W. Rhodes, Koenraad Van Meerbeek

“…However, it is clear that there are many pitfalls when measuring temperature using these devices. Here we address the problem of measuring temperatures in these microenvironments accurately. …”
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The application of allelopathy in integrated pest management systems to control temperate European crop pests: a systematic map by Charlotte Kiely, Nicola Randall, Magda Kaczorowska-Dolowry

“…One source of biopesticides is allelochemicals, here defined as compounds released by an organism that have an inhibitory or stimulatory effect on neighbouring organisms. …”
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Impact of Improved Sanitation Standard Operating Procedures on Microbial Populations at Three Tree Fruit Packing Facilities by M. Laura Rolon, Marysabel Mendez Acevedo, Priscilla Sinclair, Dumitru Macarisin, Luke F. LaBorde, Jasna Kovac

“…Cleaning and sanitizing are of vital importance to control Listeria monocytogenes in food processing facilities. Here, we evaluated the effect of four cleaning and sanitation standard operating procedures (SSOPs; T1, T2, T3, T4) on the reduction of total aerobic mesophilic microorganisms, the occurrence of L. monocytogenes, and the microbiota composition in three tree fruit packing facilities (F1, F2, and F3) over two packing seasons (Y1 and Y2). …”
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Sir2 and Fun30 regulate ribosomal DNA replication timing via MCM helicase positioning and nucleosome occupancy by Carmina Lichauco, Eric J Foss, Tonibelle Gatbonton-Schwager, Nelson F Athow, Brandon Lofts, Robin Acob, Erin Taylor, James J Marquez, Uyen Lao, Shawna Miles, Antonio Bedalov

“…By developing a method that can distinguish activation of closely spaced MCM complexes, here we show that the displaced MCMs at rDNA origins have increased firing propensity compared to the nondisplaced MCMs. …”
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Validation of a Novel Immunoline Assay for Patient Stratification according to Virulence of the Infecting Helicobacter pylori Strain and Eradication Status by Luca Formichella, Laura Romberg, Hannelore Meyer, Christian Bolz, Michael Vieth, Michael Geppert, Gereon Göttner, Christina Nölting, Wolfgang Schepp, Arne Schneider, Kurt Ulm, Petra Wolf, Ingrid Lisanne Holster, Ernst J. Kuipers, Bernd Birkner, Erwin Soutschek, Markus Gerhard

“…The presence of H. pylori virulence factors, such as CagA and VacA, has been associated with disease development, but assessment of virulence factor presence requires gastric biopsies. Here, we evaluate the H. pylori recomLine test for risk stratification of infected patients by comparing the test score and immune recognition of type I or type II strains defined by the virulence factors CagA, VacA, GroEL, UreA, HcpC, and gGT with patient’s disease status according to histology. …”
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Plant-nanoparticles enhance anti-PD-L1 efficacy by shaping human commensal microbiota metabolites by Yun Teng, Chao Luo, Xiaolan Qiu, Jingyao Mu, Mukesh K. Sriwastva, Qingbo Xu, Minmin Liu, Xin Hu, Fangyi Xu, Lifeng Zhang, Juw Won Park, Jae Yeon Hwang, Maiying Kong, Zhanxu Liu, Xiang Zhang, Raobo Xu, Jun Yan, Michael L. Merchant, Craig J. McClain, Huang-Ge Zhang

“…However, the complexity of dietary components makes it difficult to predict specific outcomes. Here we investigate the impact of plant-derived nanoparticles (PNP) on gut microbiota and metabolites in context of cancer immunotherapy with the humanized gnotobiotic mouse model. …”
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A nanocarrier containing carboxylic and histamine groups with dual action: acetylcholine hydrolysis and antidote atropine delivery by Elina E. Mansurova, Andrey A. Maslennikov, Anna P. Lyubina, Alexandra D. Voloshina, Irek R. Nizameev, Marsil K. Kadirov, Anzhela A. Mikhailova, Polina V. Mikshina, Albina Y. Ziganshina, Igor S. Antipin

“…This approach will ensure timely delivery of the antidote and minimize side effects associated with uncontrolled drug release. Here, we describe the creation of a new smart system that serves as a carrier for delivering an antidote (i.e., atropine) and functions as a synthetic esterase to hydrolyze acetylcholine. …”
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Analog parallel processor for broadband multifunctional integrated system based on silicon photonic platform by Na Qian, Defu Zhou, Haowen Shu, Ming Zhang, Xingjun Wang, Daoxin Dai, Xiao Deng, Weiwen Zou

“…However, broadband multifunctional integrated systems with large operating frequency ranges are challenging due to the bandwidth and computing speed restrictions of electronic circuitry. Here, we report an analog parallel processor (APP) based on the silicon photonic platform that directly discretizes and parallelizes the broadband signal in the analog domain. …”
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Therapeutic drug monitoring and neutralizing anti-drug antibody detection to optimize TNF-alpha inhibitor treatment for uveitis by Howard C. Chen, Jenny Shunyakova, Amit K. Reddy, Srujay Pandiri, Lynn Hassman

“…Patients who have a suboptimal response to this treatment may suffer from recurrent inflammation and vision loss. Here, we investigated the use of therapeutic drug monitoring and neutralizing anti-drug antibody detection as a strategy to optimize tumor necrosis factor (TNF)-alpha inhibitor treatment in patients who have a suboptimal response to the initial dosing of adalimumab.MethodRetrospective cohort study performed in two tertiary referral uveitis services in the United States between 2015 to 2023. …”
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Dynamic transitions of initiator binding coordinate the replication of the two chromosomes in Vibrio cholerae by Théophile Niault, Ariel Talavera, Eric Le Cam, Sonia Baconnais, Ole Skovgaard, Florian Fournes, Léa Wagner, Hedvig Tamman, Andrew Thompson, Dannele Echemendia-Blanco, Noa Guzzi, Abel Garcia-Pino, Didier Mazel, Marie-Eve Val

“…Replication of crtS on the primary chromosome (Chr1) triggers replication of the secondary chromosome (Chr2), but the details are poorly understood. Here, we analyze RctB binding patterns in the V. cholerae genome across various cell cycle stages. …”
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Shaping the human gut microbiota: The role of canine companionship, lifestyle choices, and Blastocystis sp. by Zuzana Pavlíčková, Barbora Pafčo, Vladislav Ilík, Lee O'Brien Andersen, Milan Jirků, Kristýna Brožová, David Modrý, Oldřiška Kadlecová, Christen Rune Stensvold, Kateřina Jirků

“…The Czech Republic, known for one of the highest rates of dog ownership in Europe, provides an ideal setting for studying such relationships.Here, we investigated the impact of dog ownership and lifestyle factors (residing in cities versus villages) on the gut microbiota (specifically bacteriome). …”
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An intein-split transactivator for intersectional neural imaging and optogenetic manipulation by Hao-Shan Chen, Xiao-Long Zhang, Rong-Rong Yang, Guang-Ling Wang, Xin-Yue Zhu, Yuan-Fang Xu, Dan-Yang Wang, Na Zhang, Shou Qiu, Li-Jie Zhan, Zhi-Ming Shen, Xiao-Hong Xu, Gang Long, Chun Xu

“…Abstract The cell-type-specific recording and manipulation is instrumental to disentangle causal neural mechanisms in physiology and behavior and increasingly requires intersectional control; however, current approaches are largely limited by the number of intersectional features, incompatibility of common effectors and insufficient gene expression. Here, we utilized the protein-splicing technique mediated by intervening sequences (intein) and devised an intein-based intersectional synthesis of transactivator (IBIST) to selectively control gene expression of common effectors in multiple-feature defined cell types in mice. …”
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Intrinsically stretchable fully π-conjugated polymers with inter-aggregate capillary interaction for deep-blue flexible inkjet-printed light-emitting diodes by Mingjian Ni, Zhiqiang Zhuo, Bin Liu, Xu Han, Jing Yang, Lili Sun, Yuekuan Yang, Jiangli Cai, Xiang An, Lubing Bai, Man Xu, Jinyi Lin, Quanyou Feng, Guohua Xie, Yutong Wu, Wei Huang

“…However, obtaining high-performance conjugated polymers with an excellent intrinsically flexible and printable capacity is a great challenge due to their inherent coffee-ring effect and brittle properties. Here, we report an asymmetric substitution strategy to improve the printable and stretchable properties of deep-blue light-emitting conjugated polymers with a strong inter-aggregate capillary interaction for flexible printed polymer light-emitting diodes. …”
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Genome-Wide Identification and Expression Analysis of PkNRT Gene Family in Korean Pine (<i>Pinus koraiensis</i>) by Xinyu Zhao, Haibo Wu, Boyang Li, Pengyang Wang, Peng Zhang, Hailong Shen, Jianfei Yang

“…Therefore, exploration of the role of NRTs in response to various NO₃⁻ conditions is crucial for improving N utilization efficiency (NUE). Here, we present a comprehensive genome-wide analysis and characterization of the NRT gene family in Korean pine, an invaluable tree species cultivated extensively in northeastern China. …”
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Fusobacterium nucleatum upregulates the immune inhibitory receptor PD-L1 in colorectal cancer cells via the activation of ALPK1 by Coco Duizer, Moniek Salomons, Merel van Gogh, Sanne Gräve, Freke A. Schaafsma, Maaike J. Stok, Merel Sijbranda, Raghuvandhanan Kumarasamy Sivasamy, Rob J. L. Willems, Marcel R. de Zoete

“…However, the exact manner in which F. nucleatum promotes inflammation in the tumor microenvironment and subsequent tumor promotion remains underexplored. Here, we show that both living F. nucleatum and sterile F. nucleatum-conditioned medium promote CXCL8 release from the intestinal adenocarcinoma HT-29 cell line. …”
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Caudate Nucleus Volume Mediates the Link between Cardiorespiratory Fitness and Cognitive Flexibility in Older Adults by Timothy D. Verstynen, Brighid Lynch, Destiny L. Miller, Michelle W. Voss, Ruchika Shaurya Prakash, Laura Chaddock, Chandramallika Basak, Amanda Szabo, Erin A. Olson, Thomas R. Wojcicki, Jason Fanning, Neha P. Gothe, Edward McAuley, Arthur F. Kramer, Kirk I. Erickson

“…In neocortical areas, higher cardiorespiratory fitness levels are associated with increased gray matter volume, and these volumetric differences mediate enhanced cognitive performance in a variety of tasks. Here we examine whether cardiorespiratory fitness correlates with the volume of the subcortical nuclei that make up the basal ganglia and whether this relationship predicts cognitive flexibility in older adults. …”
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