Prenatal Silicon Dioxide Nanoparticles Exposure Reduces Female Offspring Fertility Without Affecting Males by Min Lei, Zhenye Zhu, Chenlu Wei, Huihui Xie, Ruizhi Guo, Yanqing Zhao, Keer Wang, Mengchen Wang, Wenhui Chen, Xiqiao Xu, Xinxin Zeng, Yining Xu, Wandi Zhang, Yizhe Chu, Yingpu Sun, Qingling Yang

“…However, their reproductive toxicity remains unclear. Here, it is found that prenatal SiO2 NPs exposure led to subfertility in female offspring, evidenced by decreased ovulation potential, ovarian reserve, and litter size. …”
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Palaeoproteomic identification of a whale bone tool from Bronze Age Heiloo, the Netherlands by Dekker, Joannes A. A., Mylopotamitaki, Dorothea, Verbaas, Annemieke, Sinet-Mathiot, Virginie, Presslee, Samantha, McCarthy, Morgan L., Olsen, Morten Tange, Olsen, Jesper V., van den Hurk, Youri, Brattinga, Joris, Welker, Frido

“…However, the taxonomic identification of bone tools is often unsuccessful based on morphology. Here we apply three palaeoproteomic techniques, ZooMS, SPIN-like data analysis and a targeted database search to narrow down the taxonomic identification of an unusually large Bronze Age bone tool from Heiloo, the Netherlands, to the North Atlantic right whale (Eubalaena glacialis). …”
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Genotyped cluster investigations versus standard contact tracing: comparative impact on latent tuberculosis infection cascade of care in a low-incidence region by Michael Asare-Baah, Marie Nancy Séraphin, LaTweika A.T. Salmon-Trejo, Lori Johnston, Lina Dominique, David Ashkin, Krishna Vaddiparti, Awewura Kwara, Anthony T. Maurelli, Michael Lauzardo

“…Although genotyped cluster investigations may be superior to contact investigations in generating additional epidemiological links, this may not necessarily translate into reducing infections. Here, we investigated the impact of genotyped cluster investigations compared to standard contact investigations on the LTBI care cascade in a low incidence setting. …”
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Severe pneumonia caused by Nocardia otitidiscaviarum in a patient with bronchiectasis and IgA nephropathy: a case report by Yi Lin, Zhao-Zhao Jiang, Xiao-Qian Chi, Jian-Sheng Chen, Chao Wen, Chao Zhang, Ying-Ying Wang, Guang-Liang Xie

“…BackgroundNocardia species are rare opportunistic pathogens in the clinic, with strong invasiveness and dissemination, that can cause serious pulmonary infection, especially in immunocompromised patients, chronic lung diseases and hormone use, and is easy to be missed and misdiagnosed, preventing patients from obtaining timely and effective treatment, resulting in a high mortality rate.Case presentationHere, we present a rare case of a patient with chronic bronchiectasis and IgA nephropathy who developed Nocardia otitidiscaviarum pneumonia shortly after hormone therapy. …”
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Development of the cultural tailoring score (CTS): a scoring instrument to assess cultural tailoring of health messaging by Claudia Parvanta, Kayleigh Murray, Samantha Boddupalli, Natalie Erasme, Rheese McNab, Vijay Prajapati, Arabel Severe, Aura Reyes, Richard Harner, Rhonda Holliday

“…It is based on research demonstrating the importance of: (1) Levels of engagement of the intended audience in the production, (2) use of understandable and culturally meaningful language, incorporation of (3) surface cultural cues and (4) deeper cultural constructs, (5) presence of a narrative to bind the information and cultural elements into a relatable story, and (6) factors associated with concrete psychological construal level (“now,” “here,” “you”).Methods We document a trial of the cultural tailoring score conducted by graduate students identifying as Filipino, Haitian, or Hispanic/Latinx reviewing 17 ads promoting COVID-19 vaccine that had been pretested during the pandemic for perceived effectiveness with convenience samples of these same ethnic groups.Results We achieved a combined Spearman’s Rank Correlation rho of 0.45 between the cultural tailoring score and perceived effectiveness ranking of all 17 ads (individual cultural groupings range from Spearman’s rho 0.45 to 0.90), suggesting that cultural components were moderately to strongly associated with perceived effectiveness. …”
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ARMTRAJ: a set of multipurpose trajectory datasets augmenting the Atmospheric Radiation Measurement (ARM) user facility measurements by I. Silber, J. M. Comstock, M. R. Kieburtz, L. M. Russell

“…However, as with other ground-based datasets, the fixed (Eulerian) nature of these measurements often introduces a knowledge gap in relating those observations with air-mass hysteresis. Here, we describe ARMTRAJ (<span class="uri">https://doi.org/10.5439/2309851</span>, Silber, 2024a; <span class="uri">https://doi.org/10.5439/2309849</span>, Silber, 2024b; <span class="uri">https://doi.org/10.5439/2309850</span>, Silber, 2024c; <span class="uri">https://doi.org/10.5439/2309848</span>, Silber, 2024d), a set of multipurpose trajectory datasets that helps close this gap in ARM deployments. …”
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The probability of detecting host-specific microbial source tracking markers in surface waters was strongly associated with method and season by Claire M. Murphy, Daniel L. Weller, Tanzy M. T. Love, Michelle D. Danyluk, Laura K. Strawn

“…This highlights the need for standardization of methods for MST marker detection across studies but also suggests that other factors, beyond those non-methodological variables considered here, influenced variation in the likelihood of MST marker detection.IMPORTANCEThis study underscores complications associated with comparing findings from studies that used different methodologies to detect the same fecal targets and highlights the difficulties associated with using non-comparable data to generalize findings and develop science-based risk management plans. …”
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Anti-microbial cetylpyridinium chloride suppresses mast cell function by targeting tyrosine phosphorylation of Syk kinase by Bright Obeng, Lucas J. Bennett, Bailey E. West, Dylan J. Wagner, Patrick J. Fleming, Morgan N. Tasker, Madeleine K. Lorenger, Dorothy R. Smith, Tetiana Systuk, Sydni M. Plummer, Jeongwon Eom, Marissa D. Paine, Collin T. Frangos, Michael P. Wilczek, Juyoung K. Shim, Melissa S. Maginnis, Julie A. Gosse

“…Thus, a root mechanism for CPC effect might be electrostatic disruption of particular tyrosine phosphorylation events essential for signaling. This work presented here outlines biochemical mechanisms underlying the effects of CPC on immune signaling.…”
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Chronic inflammation in post-acute sequelae of COVID-19 modulates gut microbiome: a review of literature on COVID-19 sequelae and gut dysbiosis by Najeeha Talat Iqbal, Hana Khan, Aqsa Khalid, Syed Faisal Mahmood, Nosheen Nasir, Iffat Khanum, Isadora de Siqueira, Wes Van Voorhis

“…Two proposed mechanisms are discussed here. The first mechanism is related to the dysfunction of angiotensin-converting enzyme 2 receptor due to Severe Acute Respiratory Syndrome Corona Virus 2 infection, leading to impaired mTOR pathway activation, reduced AMP secretion, and causing dysbiotic changes in the gut. …”
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Performance and stability analysis of all-perovskite tandem photovoltaics in light-driven electrochemical water splitting by Junke Wang, Bruno Branco, Willemijn H. M. Remmerswaal, Shuaifeng Hu, Nick R. M. Schipper, Valerio Zardetto, Laura Bellini, Nicolas Daub, Martijn M. Wienk, Atsushi Wakamiya, Henry J. Snaith, René A. J. Janssen

“…However, their application is limited by deficits in open-circuit voltage and, more challengingly, poor operational stability of the photovoltaic cell. Here we report a laboratory-scale solar-assisted water-splitting system using an electrochemical flow cell and an all-perovskite tandem solar cell. …”
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miR-34a Regulates Multidrug Resistance via Positively Modulating OAZ2 Signaling in Colon Cancer Cells by Yong Li, Ping Gong, Ji-xue Hou, Wei Huang, Xiao-ping Ma, Yu-li Wang, Jing Li, Xiao-bin Cui, Na Li

“…Although aberrant expression of miR-34a, an essential tumor suppressor miRNA, has been frequently observed in colon cancer (CCa), whether miR-34a can regulate CCa progression by modulating other facets of this malignancy (such as multidrug resistance, MDR) remains unknown. Here, we report for the first time that miR-34a expression was significantly downregulated in clinical CCa samples from oxaliplatin-resistant patients and in experimentally established multidrug-resistant CCa cells. …”
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Photonic nanojet-regulated soft microalga-robot with controllable deformation and navigation capability by Jianyun Xiong, Ziyi He, Guoshuai Zhu, Xing Li, Yang Shi, Ting Pan, Shuhan Zhong, He Wang, Zihao Su, Liliang Ye, Baojun Li, Hongbao Xin

“…However, it is still challenging to precisely control the deformation and navigation of soft micro/nanorobots to better adapt to unstructured and complex surroundings. Here, we report a photonic nanojet (PNJ)-regulated soft microalga robot (saBOT) based on Euglena gracilis with controlled deformation and precise navigation capability. …”
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Exposure to high-temperature and high-humidity environments associated with cardiovascular mortality by Yalan Wu, Xiangrong Feng, Jinmei Li, Mengjun Li, Yao Wang, Weihui Lu, Huanhuan Luo

“…However, the combined effects of temperature and humidity on CVD-related mortality remain unclear. Here we used the Global Burden of Disease (GBD) database to analyze CVD burden and its impact on the incidence of CVD in individuals exposed to high-temperature and high-humidity (HTH) environments. …”
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EV‐Elute: A universal platform for the enrichment of functional surface marker‐defined extracellular vesicle subpopulations by Willemijn S. deVoogt, Rowan Frunt, Raul M. Leandro, Casper S. Triesscheijn, Bella Monica, Ioanna Paspali, Mark Tielemans, Jerney J. J. M. François, Cor W. Seinen, Olivier G. deJong, Sander A. A. Kooijmans

“…However, it has been technically challenging to examine such functional heterogeneity due to a lack of non‐destructive methods to separate EV subpopulations based on their surface markers. Here, we used the Design‐of‐Experiments (DoE) methodology to optimize a protocol, which we name ‘EV‐Elute’, to elute intact EVs from commercially available Protein G‐coated magnetic beads. …”
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Synergistic effect of porous structure and gradient structure in carbon foam to boost terahertz absorption by Xiao Sun, Lipeng Wu, Congli Zhou, Dun Lu, Shangzhi Chen, Mingduo Yang, Chaoyang Kuang, Wenjie Fu, Xuesong Li, Zhaoyun Duan, Qiye Wen

“…However, the synergistic effect of porous structure and gradient structure on THz absorption still remains less explored. Here, we took an almost non-conductive porous carbon foam as raw material, and fabricated an integrated gradient porous carbon foam (PCF) by microwave selective sintering. …”
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Alginate-based encapsulation of porcine placenta extract: Preparation, enteric sustained release, biological activities, and stability by Anukul Taweechaipaisankul, Nutthanit Thumrongsiri, Walailuk Chonniyom, Paweena Dana, Prattana Tanyapanyachon, Monthira Rattanatayarom, Wannapa Chinchoosak, Nattika Saengkrit

“…Microencapsulation represents a promising technique to increase the use of valuable biowaste, as well as to promote its bioavailability and stability. Here, alginate microbeads containing porcine placenta extracts (pPEs) were developed by the ionotropic gelation method under various conditions, and many of their properties were tested. …”
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The Effects of Digital eHealth Versus Onsite 2-Day Group-Based Education in 255 Patients With Irritable Bowel Syndrome: Cohort Study by Birgitte Berentsen, Camilla Thuen, Eline Margrete Randulff Hillestad, Elisabeth Kjelsvik Steinsvik, Trygve Hausken, Jan Gunnar Hatlebakk

“…Overall, patients categorized as intervention responders in both programs showed a significant reduction in symptom severity at 3 months. Here, 41% (29/71) of patients attending the eHealth program reported a mean IBS-SSS reduction of 103 (SD 72.0) points (PPPPP ConclusionsWe conclude that the digital multidisciplinary eHealth program has a significant effect on in a portion of patients; it is useful as a tool in disease self-management and does not result in worse symptom scores than an onsite multidisciplinary 2-day group-based education program after 3 months. …”
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Autophagy Contributes to Host Immunity and Protection against Zika Virus Infection via Type I IFN Signaling by Yuyi Huang, Yujie Wang, Shuhui Meng, Zhuohang Chen, Haifan Kong, Ting Pan, Gen Lu, Xuefeng Li

“…Recent studies have indicated that the Zika virus (ZIKV) has a significant impact on the fetal brain, and autophagy is contributing to host immune response and defense against virus infection. Here, we demonstrate that ZIKV infection triggered increased LC3 punctuation in mouse monocyte-macrophage cell line (RAW264.7), mouse microglial cell line (BV2), and hindbrain tissues, proving the occurrence of autophagy both in vitro and in vivo. …”
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Neuronal Multi Unit Activity Processing with Metal Oxide Memristive Devices by Caterina Sbandati, Xiongfei Jiang, Deepika Yadav, Spyros Stathopoulos, Dana Cohen, Alex Serb, Shiwei Wang, Themis Prodromakis

“…Initially tested on spikes and local field potentials, here MIS is adapted to process multi‐unit activity envelope (eMUA)—the envelope of entire spiking activity—which has recently been proposed as crucial input for real‐time neuro‐prosthetic control. …”
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القواعد الناظمة لشركة المضاربة بين النظرية والتطبيق القضائي: دراسة مقارنة بين القانونين الفلسطيني والأردني... by Anas Abu Musa Aloun

“… Speculative contract is one of the common contracts in practical reality, where a person who owns cash capital or other assets resorts to a merchant and delivers this capital to him for development and investment, and the reason for this contract is either that the owner of capital does not know trade and seeks to achieve profit and investment, or that he wants to increase his income without exerting effort, and we are here before a type of companies but this company has a special nature that does not comply with the rules stipulated in Decree-Law No. 42 of 2021 regarding companies, but rather complies with civil law rules. …”
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