Increased vulnerability of Arctic potential ice roads under climate change by Yuanbiao Dong, Pengfeng Xiao, Xueliang Zhang, Daqing Ge, Junchuan Yu, Yangyang Chen, Qiong Wu, Yanni Ma, Rongyuan Liu, Wenbo Luan, Hao Liu, Jie Bai

“…In the context of the Arctic amplified warming, the vulnerability of potential ice roads under the influence of complex climate system remains unclear. Here, we construct a potential ice road assessment model that allows quantization of the climatic suitability of potential ice roads in the Arctic. …”
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Thermal and Aerodynamic Researches of Staggered Bundles for Choice of an Effective Spacing of Round-Finned Tubes by V. B. Kuntysh, A. B. Sukhotskii, G. S. Marshalova, V. V. Dudarev, V. N. Farafontov

“…The heat transfer rate of the last transverse row in the direction of air movement is 0–5 % lower than the heat transfer rate of the stabilized rows, and here new features of heat transfer variations in the insufficiently studied area of spacing changes S1 and S2 have been found. …”
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Camel milk is a neglected source of brucellosis among rural Arab communities by Peter Holloway, Matthew Gibson, Tanja Holloway, Iain Pickett, Brittany Crook, Jacqueline M. Cardwell, Stephen Nash, Imadidden Musallam, Bilal Al-Omari, Ahmad Al-Majali, Wail Hayajneh, Ehab Abu-Basha, Punam Mangtani, Javier Guitian

“…To investigate the potential public health impact of Brucella in camels we conduct a cross-sectional study in southern Jordan including 227 herds and 202 livestock-owning households. Here we show daily consumption of raw camel milk is associated with Brucella seropositive status among the study population, ORadj 2.19 (95%CI 1.23–3.94) on multivariable analysis, highlighting the need for socioculturally appropriate control measures; targeted interventions among the camel reservoir being crucial for effective control.…”
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The Effect of Lithium on Inflammation-Associated Genes in Lipopolysaccharide-Activated Raw 264.7 Macrophages by Raymond T. Makola, Vusi G. Mbazima, Matlou P. Mokgotho, Vincent S. Gallicchio, Thabe M. Matsebatlela

“…Lithium has been shown to lower the production of the chemokine RANTES; furthermore, this inhibitory action of lithium has been suggested to be independent of glycogen synthase kinase-3 β (GSK3β) activity. It is shown here that lithium modulates the expression of several inflammatory genes including IκB-α, TRAF3, Tollip, and NF-κB1/p50 which are regulators of the NF-κB pathway. …”
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The Shiism Dimension in Iran's Relations with Europe: The Example of Germany-France-United Kingdom by Orhan Karaoğlu

“…Its relationship with the Shiite communities here appears as an important element in Iran's relations with European countries in the context of foreign policy. …”
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H. Pylori‐Facilitated TERT/Wnt/β‐Catenin Triggers Spasmolytic Polypeptide‐Expressing Metaplasia and Oxyntic Atrophy by Lijiao He, Xiao Zhang, Shengwei Zhang, Yi Wang, Weichao Hu, Jie Li, Yunyi Liu, Yu Liao, Xue Peng, Jianjun Li, Haiyan Zhao, Liting Wang, Yang‐Fan Lv, Chang‐Jiang Hu, Shi‐Ming Yang

“…However, the mechanism underlying the initiation of SPEM in gastric tissues by H. pylori remains unclear. Here, an increase in telomerase reverse transcriptase (TERT) protein expression is observed in chief cells upon infection with cagA‐positive H. pylori. …”
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Declines in anthropogenic mercury emissions in the Global North and China offset by the Global South by Xinran Qiu, Maodian Liu, Yuanzheng Zhang, Qianru Zhang, Huiming Lin, Xingrui Cai, Jin Li, Rong Dai, Shuxiu Zheng, Jinghang Wang, Yaqi Zhu, Huizhong Shen, Guofeng Shen, Xuejun Wang, Shu Tao

“…Currently, consistent methodologies to evaluate long-term mercury emissions across countries and industries are scant, hindering efforts to prioritize emission controls. Here, we develop a high-spatiotemporal-resolution dataset to comprehensively analyze global anthropogenic mercury emission patterns. …”
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Geohazard features of the Northern Sardinia by Alessandro Conforti, Francesca Budillon, Giovanni De Falco, Giacomo Deiana, Valentino Demurtas, Gabriella Di Martino, Sara Innangi, Antonietta Meleddu, Paolo Emanuele Orrù, Enrico Pagliaga, Simone Simeone, Renato Tonielli

“…The maps of the geohazard-related features of the North Sardinia continental margin produced by the Magic project (MArine Geohazard along Italian Coasts) are here presented. The maps were created on the base of morphobathymetric data obtained by with multibeam echo sounders. …”
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Molecular identification and antibiotic clearance of Mycoplasma arginini and Mycoplasma orale from cell cultures infected with Rickettsia or Ehrlichia species by Michelle E. J. Allerdice, Savannah L. Shooter, Maria F. B. M. Galletti, Joy A. Hecht, Sandor E. Karpathy, Christopher D. Paddock

“…As such, the comprehensive strategy for Mycoplasma arginini and Mycoplasma orale elimination presented here can improve laboratory efficiency for in vitro research with intracellular bacteria.…”
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Endogenous endophthalmitis associated with autoimmune hepatitis: case report by D.F. Belov, V.G. Korotkov, P.A. Nikitin, I.V. Terekhova, Ya.S. Konenkova

“…After canceling steroids, AIH progressed to cirrhosis. Here, the development of EE was probably associated with secondary immunodeficiency in the setting of AIH. …”
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The Effect of Annealing in a Magnetic Field on the Microstructures and Magnetic Properties of (Nd_0.8RE_0.2)_2.2Fe₁₂Co₂B (RE = L... by Xiaohua Tan, Xuanbo Shi, Shiqi Zhang, Hui Xu

“…The development of high-performance and cost-effective Nd-Fe-B permanent magnets is crucial to meet the ever-growing requirements of renewable and clean energy applications. Here, we use low-cost and highly abundant La and Ce to partially substitute Nd and investigate the effect of annealing treatment with a 1 tesla (T) magnetic field on the microstructures and magnetic properties of (Nd_0.8RE_0.2)_2.2Fe₁₂Co₂B (RE = La, Ce) ribbons. …”
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Usefulness of Magnifying Endoscopy with Narrow-Band Imaging for Determining Tumor Invasion Depth in Early Gastric Cancer by Daisuke Kikuchi, Toshiro Iizuka, Shu Hoteya, Akihiro Yamada, Tsukasa Furuhata, Satoshi Yamashita, Kaoru Domon, Masanori Nakamura, Akira Matsui, Toshifumi Mitani, Osamu Ogawa, Sumio Watanabe, Mitsuru Kaise

“…Magnifying endoscopy with narrow-band imaging (ME-NBI) has become essential for determining tumor margin in early gastric cancer (EGC). Here, we investigated the usefulness of ME-NBI for assessment of invasion depth in EGC. …”
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Targeting of retrovirus-derived Rtl8a/8b causes late-onset obesity, reduced social response and increased apathy-like behaviour by Yoshifumi Fujioka, Hirosuke Shiura, Masayuki Ishii, Ryuichi Ono, Tsutomu Endo, Hiroshi Kiyonari, Yoshikazu Hirate, Hikaru Ito, Masami Kanai-Azuma, Takashi Kohda, Tomoko Kaneko-Ishino, Fumitoshi Ishino

“…They cluster as a triplet of genes on the X chromosome, but their function remains unknown. Here, we demonstrate that Rtl8a and Rtl8b play important roles in the brain: their double knockout (DKO) mice not only exhibit reduced social responses and increased apathy-like behaviour, but also become obese from young adulthood, similar to patients with late Prader–Willi syndrome (PWS), a neurodevelopmental genomic imprinting disorder. …”
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Mobilization and deposition of plastic along an estuarine bank during tidal cycles by Rosa Sawan, Périne Doyen, Guillaume Veillet, Florence Viudes, Céline Mahfouz, Rachid Amara

“…Limited studies have evaluated how these complex systems contribute to plastic pollution dynamics at this interface. Here, an in situ experimental study was conducted in the Slack estuary, a small macrotidal estuarine system in northern France, to investigate the mobilization and deposition of plastic debris on an estuarine bank at a daily basis during six complete tidal cycles. …”
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Tapinarof Improved Outcomes and Sleep for Patients and Families in Two Phase 3 Atopic Dermatitis Trials in Adults and Children by Eric L. Simpson, Adelaide A. Hebert, John Browning, Rocco T. Serrao, Howard Sofen, Philip M. Brown, Stephen C. Piscitelli, David S. Rubenstein, Anna M. Tallman

“…In two phase 3 trials (ADORING 1 and 2), tapinarof cream 1% once daily (QD) demonstrated significant efficacy and was well tolerated in patients down to age 2 years with AD. Here, we evaluate patient-reported outcomes (PROs), including family impact, with tapinarof in ADORING 1 and 2. …”
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Cardiovascular Development and the Colonizing Cardiac Neural Crest Lineage by Paige Snider, Michael Olaopa, Anthony B. Firulli, Simon J. Conway

“…Several groups have used the genetically defined Pax3 (splotch) mutant mice model to address the role of the cardiac neural crest lineage. Here we review the current literature, the neural crest-related role of the Pax3 transcription factor, and discuss potential function/s of cardiac neural crest-derived cells during cardiovascular developmental remodeling.…”
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Parametrization of the dying brain: A case report from ICU bed-side EEG monitoring by Sebastian Zinn, Srdjan Z. Dragovic, Jan A. Kloka, Laurent M. Willems, Sebastian Harder, Stephan Kratzer, Kai D. Zacharowski, Gerhard Schneider, Paul S. García, Matthias Kreuzer

“…Background: Cortical high-frequency activation immediately before death has been reported, raising questions about an enhanced conscious state at this critical time. Here, we analyzed an electroencephalogram (EEG) from a comatose patient during the dying process with a standard bedside monitor and spectral parameterization techniques. …”
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Annealing temperature modify of crystalline structure, magnetic properties and antibacterial performance in nickel substituted cobalt ferrite nanoparticles utilizing natural-fine-s... by Laksmita Farah Bestari, Lathifah Iqlimatussholihah, Nurdiyantoro Putra Prasetya, Kusumandari, Utari, Riyatun, Budi Purnama

“…In case of NiCFO-fs samples, magnetization saturation (MS) decreased with the increase of the Ta in contrast to NiCFO-pa samples. Here, the redistribution of two and three plus ions in the sub-lattice k1 and k2 locations should be encouraged by the Jahn-Teller phenomenon through strain-induced magnetism. …”
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Endothelial-Ercc1 DNA repair deficiency provokes blood-brain barrier dysfunction by Cathrin E. Hansen, Davide Vacondio, Lennart van der Molen, Annika A. Jüttner, Wing Ka Fung, Manon Karsten, Bert van het Hof, Ruud D. Fontijn, Gijs Kooij, Maarten E. Witte, Anton J. M. Roks, Helga E. de Vries, Inge Mulder, Nienke M. de Wit

“…Among other factors, DNA damage strongly promotes cellular aging, however, the role of genomic instability in brain endothelial cells (EC) and its potential effect on brain homeostasis is still largely unclear. We here investigated how endothelial aging impacts blood-brain barrier (BBB) function by using excision repair cross complementation group 1 (ERCC1)-deficient human brain ECs and an EC-specific Ercc1 knock out (EC-KO) mouse model. …”
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Cloned airway basal progenitor cells to repair fibrotic lung through re-epithelialization by Yu Zhao, Yueqing Zhou, Weipan Zhang, Mingzhe Liu, Jun Duan, Xiaopeng Zhang, Qiwang Ma, Yujia Wang, Yuzhen Zhang, Zhongliang Guo, Ting Zhang, Wei Zuo

“…Abstract Irreversible damage of the lung epithelium in idiopathic pulmonary fibrosis (IPF) patients causes high mortality worldwide, with no lung repair approaches available currently. Here we show that in murine and monkey models, the KRT5+ P63+ progenitor cells in airway basal layer can enter the alveolar area post fibrotic injury. …”
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