Severe fever with thrombocytopenia syndrome complicated with aspergillus endocarditis and multiple organ infarctions after glucocorticoid treatment in an immunocompetent man: a cas... by Yuxi Zhao, Xiaoxin Wu, Xinyu Wang, Lanjuan Li

“…Previous studies have reported cases of SFTS complicated with invasive pulmonary aspergillosis (IPA) and central nervous system aspergillosis. Here, we present the first case of an immunocompetent patient with SFTS who progressed to IPA and Aspergillus endocarditis after glucocorticoid treatment, and embolism of the vegetations from the left ventricle led to multiple infarctions in the brain, kidney, and spleen. …”
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Self-Expandable Metal Stent Placement for Closure of a Leak after Total Gastrectomy for Gastric Cancer: Report on Three Cases and Review of the Literature by Dario Raimondo, Emanuele Sinagra, Tiziana Facella, Francesca Rossi, Marco Messina, Massimiliano Spada, Guido Martorana, Pier Enrico Marchesa, Rosario Squatrito, Giovanni Tomasello, Attilio Ignazio Lo Monte, Giancarlo Pompei, Ennio La Rocca

“…In the setting of the curative oncological surgery, the gastric surgery is exposed to complicated upper gastrointestinal leaks, and consequently the management of this problem has become more critically focused than was previously possible. We report here three cases of placement of a partially silicone-coated SEMS (Evolution Controlled Release Esophageal Stent System, Cook Medical, Winston-Salem, NC, USA) in patients who underwent total gastrectomy with Roux-en-Y end-to-side esophagojejunostomy for a gastric adenocarcinoma. …”
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Searching for More Effective Food Baits for Tephritid Fruit Flies (Diptera: Tephritidae): Performance of Newly Developed Vial-Lures Relative to Torula Yeast Borax by Walther Enkerlin, Emilio Arevalo, Jose Eduardo Caballero, Thomas Fezza, Esteban Garavelli, Diana Beatriz Martinez, Pedro Alexander Rodriguez, Todd Shelly, Milthon Edgardo Thomas, Antonio Villaseñor, Salvador Flores

“…However, the different formulations of these synthetic lures vary greatly in their attractiveness and longevity. Here, we present the results of field trapping in several Central and South American countries as well as Hawaii that compared captures of <i>Ceratitis capitata</i>, <i>Anastrepha</i> spp., and <i>Bactrocera dorsalis</i> in traps baited with torula yeast borax, which was replaced weekly, versus traps baited with newly developed vial-lures, which contained the same three components noted above and were not replaced over 6–10 weeks of trapping. …”
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Expression and localization of two β-carbonic anhydrases in Bienertia, a single-cell C4 plant by Tho Nguyen, Nakyoung Lee, Fabian J. Frömling, Toni L. Meister, Toni L. Meister, Toni L. Meister, Jung Sun Kim, Sascha Offermann, Inhwan Hwang

“…Higher plants contain many different isoforms of CAs that can be classified into α-, β- and γ-type subfamilies. β-type CAs play a key role in the CO2-concentrating mechanism, thereby contributing to efficient photosynthesis in the C4 plants in addition to many other biochemical reactions in plant metabolism. Here, we characterized at the molecular, cellular and biochemical levels two β-type CAs in Bienertia sinuspersici, a plant that operates a C4 carbon concentrating mechanism within individual cells without the Kranz anatomy. …”
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USP14 is crucial for proteostasis regulation and α-synuclein degradation in human SH-SY5Y dopaminergic cells by Vignesh Srinivasan, Rabah Soliymani, Larisa Ivanova, Ove Eriksson, Nina Peitsaro, Maciej Lalowski, Mati Karelson, Dan Lindholm

“…Ubiquitin specific protease-14 (USP14) is critical for controlling proteostasis disturbed in human disorders, including Parkinson's disease (PD). Here we investigated USP14 in the regulation of α-synuclein (α-syn) degradation via the proteasome and autophagy. α-Syn and pS129 α-syn were elevated in USP14 gene-deleted SH-SY5Y dopaminergic cells with decreased proteasome activity. …”
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ALCAM is an entry factor for severe community acquired Pneumonia-associated Human adenovirus species B by Yusang Xie, Hong Mei, Wei Wang, Xiao Li, Pengfei Hu, Xingui Tian, Rong Zhou, Jia Liu, Jieming Qu

“…However, the connection between SCAP-associated HAdV-B infection and host factor expression profile in patients has not been systematically investigated. Here, we perform a CRISPR genetic screen on HAdV-B using two generations of cell surface protein-focused CRISPR libraries and identify a series of host factors including the known receptor DSG-2 and an unknown factor, activated leukocyte cell adhesion molecule (ALCAM). …”
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Foreword

“…Their commitment to advancing Korean Studies globally has been fundamental to the scholarly efforts presented here. This issue highlights the vibrancy and interdisciplinarity of Korean Studies, offering fresh perspectives and fostering dialogue. …”
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Avolition Characterizes the Chronic Fatigue Experienced in Quiescent Inflammatory Bowel Disease by Tristan Gabriel-Segard, Margherita Boltri, Mathilde Barrau, Catherine Massoubre, Stéphane Paul, Xavier Roblin

“…Fatigue is a widespread complaint of patients suffering from inflammatory bowel disease (IBD), significantly impacting patients’ well-being, even during the quiescent stage of the disease. We here address the hypothesis that fatigue experienced by IBD patients is associated with motivational impairment. …”
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Glioblastoma drives protease-independent extracellular matrix invasion of microglia by Chia-Wen Chang, Ashwin Bale, Rohit Bhargava, Brendan A.C. Harley

“…Improved physicochemical understanding of microglia activation and invasion may provide novel GBM therapeutic strategies essential for improving long-term treatment efficacy. Here, we combine microfluidic systems with 3-D collagen hydrogels to systematically investigate microglia activation, invasion, contractility and cytokine secretion in response to GBM-microglia crosstalk. …”
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CHAMP1 premature termination codon mutations found in individuals with intellectual disability cause a homologous recombination defect through haploinsufficiency by Yujiro Yoshizaki, Yunosuke Ouchi, Dicky Kurniawan, Eisuke Yumoto, Yuki Yoneyama, Faiza Ramadhani Rizqullah, Hiyori Sato, Mirjam Hanako Sarholz, Toyoaki Natsume, Masato T. Kanemaki, Masanori Ikeda, Ayako Ui, Kenji Iemura, Kozo Tanaka

“…How these mutations affect the functions of CHAMP1 has not been clarified yet. Here we investigated the effects of the CHAMP1 mutations on HR. …”
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Extreme migratory connectivity and apparent mirroring of non-breeding grounds conditions in a severely declining breeding population of an Afro-Palearctic migratory bird by Máire Kirkland, Nathaniel N. D. Annorbah, Lee Barber, John Black, Jeremy Blackburn, Michael Colley, Gary Clewley, Colin Cross, Mike Drew, Oliver J. L. Fox, Vicky Gilson, Steffen Hahn, Chas Holt, Mark F. Hulme, John Jarjou, Dembo Jatta, Emmanuel Jatta, Kevin Leighton, Ernestina Mensah-Pebi, Chris Orsman, Naffie Sarr, Roger Walsh, Leo Zwarts, Robert J. Fuller, Philip W. Atkinson, Chris M. Hewson

“…These results support hypotheses that climatic and habitat-related deterioration of non-breeding grounds contributes to population declines in peripheral and high-connectivity breeding populations of long-distance migrants, including the one studied here.…”
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Application of artificial intelligence brain structure-based paradigm to predict the slip condition impact on magnetized thermal Casson viscoplastic fluid model under combined temp... by Umar Farooq, Shan Ali Khan, Haihu Liu, Muhammad Imran, Lotfi Ben Said, Aleena Ramzan, Taseer Muhammad

“…Results obtained for regression metrics, absolute error, MSE and error histogram plots through the LMT-ABPNN architecture do confirm the superior performance attained here. From the results, the study raises close concordance with respect to reference data. …”
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Daily Feeding of Fructooligosaccharide or Glucomannan Delays Onset of Senescence in SAMP8 Mice by Sadako Nakamura, Naoyuki Kondo, Yoshitake Yamaguchi, Michiru Hashiguchi, Kenichi Tanabe, Chihiro Ushiroda, Miho Kawahashi-Tokuhisa, Katsuyuki Yui, Mana Miyakoda, Tsuneyuki Oku

“…We hypothesized that daily intake of nondigestible saccharides delays senescence onset through the improvement of intestinal microflora. Here, we raised senescence accelerated mice prone 8 (SAMP8) on the AIN93 diet (CONT), with sucrose being substituted for 5% of fructooligosaccharide (FOS) or 5% of glucomannan (GM), 15 mice per group. …”
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Cultural aspects of organizational agility affecting digital innovation by Dulce Goncalves, Magnus Bergquist, Richard Bunk, Sverker Alänge

“…The most successful startups were even able to create a combination of Clan and Adhocracy cultures — a concept we here term ‘Agile culture.’ This culture allowed them to reach a beneficial state of digital innovation growth. …”
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A flexible catheter-based sensor array for upper airway soft tissues pressure monitoring by Jiang Shang, Xiaoxiao Ma, Peikai Zou, Chenxiao Huang, Zhechen Lao, Junhan Wang, Tingshu Jiang, Yanzhe Fu, Jiebo Li, Shaoxing Zhang, Ruya Li, Yubo Fan

“…Accurate detection and localization of airway obstructions are crucial for effective diagnosis and treatment, which remains a challenge for traditional sleep monitoring methods. Here, we report a catheter-based flexible pressure sensor array that continuously monitors soft tissue pressure in the upper airway and facilitates at the millimeter level. …”
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Machine learning model and nomogram to predict the risk of heart failure hospitalization in peritoneal dialysis patients by Liping Xu, Fang Cao, Lian Wang, Weihua Liu, Meizhu Gao, Li Zhang, Fuyuan Hong, Miao Lin

“…Introduction The study presented here aimed to establish a predictive model for heart failure (HF) and all-cause mortality in peritoneal dialysis (PD) patients with machine learning (ML) algorithm.Methods We retrospectively included 1006 patients who initiated PD from 2010 to 2016. …”
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Insight into the codon usage patterns and adaptation of Tembusu Virus by Fucheng Guo, Huiming Tan, Jinjin Yang, Rumin Jia, Ruichen Wang, Lie Wu, Fengzhi Pan, Kai Kang, Weitian Xie, Youquan Li, Kewei Fan

“…Since its emergence in 2010, Tembusu virus (TMUV) has rapidly spread across poultry populations in Asia, leading to substantial economic losses in these areas. Here, we investigate the codon usage patterns (CUPs) underlying TMUV's adaptation and evolutionary dynamics within host environments. …”
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Role of Vigilin and RACK1 in dengue virus-Aedes aegypti-Wolbachia interactions by Guijie Wang, Mazhar Hussain, Zhi Qi, Sassan Asgari

“…Both proteins are associated with the endoplasmic reticulum. Here, we investigated the significance of Vigilin and RACK1 homologs in Aedes aegypti mosquitoes concerning DENV replication and Wolbachia infection. …”
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A Novel Approach for In Vitro Testing and Hazard Evaluation of Nanoformulated RyR2-Targeting siRNA Drugs Using Human PBMCs by Valeria Bettinsoli, Gloria Melzi, Angelica Crea, Lorenzo Degli Esposti, Michele Iafisco, Daniele Catalucci, Paolo Ciana, Emanuela Corsini

“…Beyond efficacy, addressing safety concerns—particularly those specific to this class of drugs—is crucial. Here, we propose an in vitro approach to screen for potential adverse off-target effects of NA-based drugs. …”
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OsBBX2 Delays Flowering by Repressing <i>Hd3a</i> Expression Under Long-Day Conditions in Rice by Yusi Yang, Jiaming Wei, Xiaojie Tian, Changhua Liu, Xiufeng Li, Qingyun Bu

“…Members of the B-Box (BBX) family of proteins play crucial roles in the growth and development of rice. Here, we identified a rice BBX protein, Oryza sativa BBX2 (OsBBX2), which exhibits the highest expression in the root. …”
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