Molecular Mechanisms Underlying Neuroinflammation Intervention with Medicinal Plants: A Critical and Narrative Review of the Current Literature by Sandra Maria Barbalho, Beatriz Leme Boaro, Jéssica da Silva Camarinha Oliveira, Jiří Patočka, Caroline Barbalho Lamas, Masaru Tanaka, Lucas Fornari Laurindo

“…While the anti-inflammatory potential of these plants is significant, the variability in dosages and phytochemical compositions limits clinical translation. Here, we highlight that medicinal plants are effective modulators of neuroinflammation, underscoring their therapeutic potential. …”
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Global-optimized energy storage performance in multilayer ferroelectric ceramic capacitors by Da Li, Zhaobo Liu, Weichen Zhao, Yan Guo, Zhentao Wang, Diming Xu, Houbing Huang, Li-Xia Pang, Tao Zhou, Wen-Feng Liu, Di Zhou

“…An effective strategy for energy storage performance global optimization is put up here by constructing local polymorphic polarization configuration integrated with prototype device manufacturing. …”
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Uncovering novel functions of the enigmatic, abundant, and active Anaerolineae in a salt marsh ecosystem by Paige E. Payne, Loren N. Knobbe, Patricia Chanton, Julian Zaugg, Behzad Mortazavi, Olivia U. Mason

“…However, this class generally remains poorly understood, particularly in a salt marsh context. Here, novel Anaerolineae metagenome-assembled genomes (MAGs) were generated from the salt marsh rhizosphere representing Anaerolineales, Promineifilales, JAAYZQ01, B4-G1, JAFGEY01, UCB3, and Caldilineales orders. …”
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Three-dimensional diffractive acoustic tomography by Luca Menozzi, Tri Vu, Aidan J. Canning, Harshal Rawtani, Carlos Taboada, Marie Elise Abi Antoun, Chenshuo Ma, Jesse Delia, Van Tu Nguyen, Soon-Woo Cho, Jianing Chen, Theresa Charity, Yirui Xu, Phuong Tran, Jun Xia, Gregory M. Palmer, Tuan Vo-Dinh, Liping Feng, Junjie Yao

“…However, most photoacoustic and ultrasound imaging systems rely on linear-array transducers with elevational focusing and are limited to two-dimensional imaging with anisotropic resolutions. Here, we present three-dimensional diffractive acoustic tomography (3D-DAT), which uses an off-the-shelf linear-array transducer with single-slit acoustic diffraction. …”
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Molecular Network Associated with MITF in Skin Melanoma Development and Progression by Ichiro Yajima, Mayuko Y. Kumasaka, Nguyen Dinh Thang, Yuji Goto, Kozue Takeda, Machiko Iida, Nobutaka Ohgami, Haruka Tamura, Osamu Yamanoshita, Yoshiyuki Kawamoto, Keiko Furukawa, Masashi Kato

“…To find better approaches to molecular-based therapies for patients, understanding MITF function in skin melanoma development and progression is important. Here, we review the molecular networks associated with MITF in skin melanoma development and progression.…”
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An Overview of Hybrid DC–DC Converters: From Seeds to Leaves by Yan Lu, Junwei Huang, Zhiguo Tong, Tingxu Hu, Wen-Liang Zeng, Mo Huang, Xiangyu Mao, Guigang Cai

“…This article reviews the switched-capacitor-inductor (SCI) hybrid dc–dc buck converters from the topology “seeds” to their “leaves.” Here, we define six seeds, they are: 1) three-level buck; 2) double-step down buck; 3) inductor-first buck; 4) always-dual-path buck; 5) buck–buck; and 6) multiple-output hybrid buck. …”
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Strontium Promotes the Proliferation and Osteogenic Differentiation of Human Placental Decidual Basalis- and Bone Marrow-Derived MSCs in a Dose-Dependent Manner by Yi-Zhou Huang, Cheng-Guang Wu, Hui-Qi Xie, Zhao-Yang Li, Antonietta Silini, Ornella Parolini, Yi Wu, Li Deng, Yong-Can Huang

“…Strontium enhances the osteogenic differentiation of bone marrow-derived MSCs (BM-MSCs), but whether it exerts similar effects on placental decidual basalis-derived MSCs (PDB-MSCs) remains unknown. Here, we compared the influence of strontium on the proliferation and osteogenic differentiation of human PDB- and BM-MSCs in vitro. …”
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Feasibility of individualized home exercise programs for patients with head and neck cancer-study protocol and first results of a multicentre single-arm intervention trial (OSHO #9... by Sabine Felser, Julia Rogahn, Änne Glass, Lars Arne Bonke, Daniel Fabian Strüder, Jana Stolle, Susann Schulze, Markus Blaurock, Ursula Kriesen, Christian Junghanss, Christina Grosse-Thie

“…The study includes a feasibility phase (proof of concept) in order to evaluate the acceptance. Here we present the study protocol as well as the feasibility results.…”
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11 Key Strategies in Using AI Chat GPT to Develop HOTS-Based Entrepreneurship Questionnaires by Almaida Vebibina, Rusijono Rusijono, Andi Mariono, Ahsan Muafa, Dydik Kurniawan, Ragil Sugeng Dewantoro, Dian Noer Asyari, Sussi Widiastuti, Jarot Suseno

“…Artificial intelligence such as Chat GPT is here to simplify the process. However, its use in creating HOTS-based questions in entrepreneurship still faces obstacles. …”
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Emergence of ferroelectricity in Sn-based perovskite semiconductor films by iminazole molecular reconfiguration by Yu Liu, Shuzhang Yang, Lina Hua, Xiaomin Yang, Enlong Li, Jincheng Wen, Yanqiu Wu, Liping Zhu, Yingguo Yang, Yan Zhao, Zhenghua An, Junhao Chu, Wenwu Li

“…However, it is difficult to prepare a Sn-based perovskite film with both robust ferroelectric and semiconductor properties. Here, by doping with 2-methylbenzimidazole, Sn-based perovskite [93.3 mol% (FA0.86Cs0.14)SnI3 and 6.7 mol% PEA2SnI4] semiconductor films are transformed into ferroelectric semiconductor films, owing to molecular reconfiguration. …”
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Redox-dependent purine degradation triggers postnatal loss of cardiac regeneration potential by Yuichi Saito, Yuki Sugiura, Akane Sakaguchi, Tai Sada, Chihiro Nishiyama, Rae Maeda, Mari Kaneko, Hiroshi Kiyonari, Wataru Kimura

“…Postnatal cardiomyocyte cell cycle withdrawal is a critical step wherein the mammalian heart loses regenerative potential after birth. Here, we conducted interspecies multi-omic comparisons between the mouse heart and that of the opossum, which have different postnatal time-windows for cardiomyocyte cell cycle withdrawal. …”
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Identification of Oil Vertical Migration Through Tectonic Fractures: A New Insight into the Oil Migration Process in the Central Ordos Basin, China by Yiwei Ren, Aiguo Wang, Yanjun Du, Chunyu Li, Bianyang Wang, Zilong Li, Jie Wang, Jinxiang Wei

“…Identifying oil migration through tectonic fractures in stable cratons is always challenging due to limited technical approaches. Here, we provide a case study showing that combined geochemical and geological analyses are a robust tool for identifying oil vertical migration through tectonic fractures. …”
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Autogenous Electron Acceleration by Ion Flow Vortex in Space Plasmas by C. M. Liu, J. B. Cao, Y. Y. Liu, E. A. Kronberg, X. N. Xing, B. N. Zhao, P. W. Daly

“…Plasma flow vortexes are ubiquitous in space and astrophysical settings and play a vital role in energy and mass transport, contributing to formation of stars and planets, launching and dissipation of astrophysical jets, and coupling between planetary magnetospheres and ionospheres. Here we present in situ observations showing that energetic electrons with energies up to 250 keV can be directly generated inside an ion flow vortex with finite spatial scale. …”
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Flavones enrich rhizosphere Pseudomonas to enhance nitrogen utilization and secondary root growth in Populus by Jiadong Wu, Sijia Liu, Haoyu Zhang, Sisi Chen, Jingna Si, Lin Liu, Yue Wang, Shuxian Tan, Yuxin Du, Zhelun Jin, Jianbo Xie, Deqiang Zhang

“…The importance of root microbiome variation driving plant functional traits is increasingly recognized, but the genetic mechanisms governing this variation are less studied. Here, we collect roots and rhizosphere soils from nine Populus species belonging to four sections (Leuce, Aigeiros, Tacamahaca, and Turanga), generate metabolite and transcription data for roots and microbiota data for rhizospheres, and conduct comprehensive multi-omics analyses. …”
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Effects of residential acaricide treatments on patterns of pathogen coinfection in blacklegged ticks by Richard S. Ostfeld, Sahar Adish, Stacy Mowry, William Bremer, Shannon Duerr, Andrew S. Evans, Ilya R. Fischhoff, Fiona Keating, Jennifer Pendleton, Ashley Pfister, Marissa Teator, Felicia Keesing, Ala Tabor

“…Acquisition of multiple zoonotic pathogens by immature blacklegged ticks (Ixodes scapularis) is facilitated when they feed on small mammals, which are the most competent reservoir hosts for Anaplasma phagocytophilum (which causes anaplasmosis in humans), Babesia microti (babesiosis) and Borrelia burgdorferi (Lyme disease). Here, we used data from a large-scale, long-term experiment to ask whether patterns of single and multiple infections in questing nymphal I. scapularis ticks from residential neighbourhoods differed from those predicted by independent assortment of pathogens, and whether patterns of coinfection were affected by residential application of commercial acaricidal products. …”
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Deletion of ESX-3 and ESX-4 secretion systems in Mycobacterium abscessus results in highly impaired pathogenicity by Wassim Daher, Vincent Le Moigne, Yara Tasrini, Shweta Parmar, Danielle L. Sexton, John Jairo Aguilera-Correa, Valentin Berdal, Elitza I. Tocheva, Jean-Louis Herrmann, Laurent Kremer

“…Mycobacterium abscessus, encodes only ESX-3 and ESX-4. Here, single and double M. abscessus mutants lacking the main ATPases EccC3 and EccC4 were used to define ESX-3 and ESX-4 contributions to substrate secretion and virulence. …”
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Targeting the Vasculature of Colorectal Carcinoma with a Fused Protein of (RGD)3-tTF by Zheng-jie Huang, Yilin Zhao, Wei-yuan Luo, Jun You, Shui-wen Li, Wen-cheng Yi, Sheng-yu Wang, Jiang-hua Yan, Qi Luo

“…Truncated tissue factor (tTF) fusion protein targeting tumor vasculature can induce tumor vascular thrombosis and necrosis. Here, we generated (RGD)3-tTF in which three arginine-glycine-aspartic (RGD) targeting integrin αvβ3 and tTF induce blood coagulation in tumor vessels. …”
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Healthcare utilisation by pregnant patients with asthma in South Korea: a cohort study using nationwide claims data by Deog Kyeom Kim, Chang-Hoon Lee, Ho Il Yoon, Jae-Joon Yim, Eun Jin Jang, Jimin Kim, Yun Jung Kim, Seongmi Choi, Joon-Ho Lee

“…Objectives Few nationwide population-based studies have examined the burden of asthma during pregnancy. Here, we investigated the burden and medical treatment of asthma during pregnancy requiring healthcare utilisation in South Korea.Design Cohort study.Setting Nationwide insurance claims database.Participants A total of 1 306 281 pregnant women who delivered in South Korea in 2009–2011.Outcomes The prevalence and exacerbation rates of asthma requiring healthcare utilisation, and the prescription of antiasthmatic drugs during pregnancy.Results The prevalence of asthma requiring healthcare utilisation was 0.43% among pregnant women. …”
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House Dust Mite and Cat Dander Extract Induce Asthma-Like Histopathology with an Increase of Mucosal Mast Cells in a Guinea Pig Model by Patricia Ramos-Ramírez, Jielu Liu, Sofia Mogren, Joshua Gregory, Malin Noreby, Anne Petrén, Ying Lei, Henric Olsson, Marianne van Hage, Jukka Kervinen, Lars Hellman, Cecilia Andersson, Gunnar Nilsson, Mikael Adner

“…This increase was primarily due to mast cells expressing tryptase, but not chymase, thus indicating mucosal mast cells. Conclusions. We here show that exposure to HDM and CDE elicits asthma-like histopathology in guinea pigs with infiltration of inflammatory cells, airway remodelling, and accumulation of primarily mucosal mast cells. …”
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G-quadruplex-forming small RNA inhibits coronavirus and influenza A virus replication by Ryoya Sekine, Kouki Takeda, Tsukasa Suenaga, Satsuki Tsuno, Takumi Kaiya, Maki Kiso, Seiya Yamayoshi, Yoshihide Takaku, Shiho Ohno, Yoshiki Yamaguchi, Seiichi Nishizawa, Kazuhiro Sumitomo, Kazufumi Ikuta, Teru Kanda, Yoshihiro Kawaoka, Hidekazu Nishimura, Shusuke Kuge

“…Abstract Future pandemic threats may be caused by novel coronaviruses and influenza A viruses. Here we show that when directly added to a cell culture, 12mer guanine RNA (G12) and its phosphorothioate-linked derivatives (G12(S)), rapidly entered cytoplasm and suppressed the propagation of human coronaviruses and influenza A viruses to between 1/100 and nearly 1/1000 of normal virus infectivity without cellular toxicity and induction of innate immunity. …”
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